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UBE2A Gene

protein-coding GIFtS: 68

GC0XP118592

ubiquitin-conjugating enzyme E2A (RAD6 homolog)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 6.3.2.19 ^³
HHR6A ^¹, ²
HR6A ^³
OTTHUMP00000023901 ^²
RAD6A ^², ³, ⁵
UBC2 ^¹, ²
hHR6A ^³

Descriptions
Ubiquitin carrier protein A ^², ³
Ubiquitin-protein ligase A ^², ³
ubiquitin-conjugating enzyme E2A ^²
ubiquitin-conjugating enzyme E2A (RAD6 homolog) ^²

External Ids
HGNC: 12472¹
Entrez Gene: 7319²
UniProtKB: P49459³
Ensembl: ENSG00000077721⁷

Search outside databases for aliases for UBE2A gene

Previous GC identifers: GC0XP113526 GC0XP115694 GC0XP116683 GC0XP117462 GC0XP118490

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for UBE2A:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting

abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes

of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and

ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating

enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple

alternatively spliced transcript variants have been found for this gene and they encode distinct

isoforms. [provided by RefSeq]

UniProtKB/Swiss-Prot: UBE2A_HUMAN, P49459

Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Required for

postreplication repair of UV-damaged DNA

Gene Wiki entry for UBE2A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the UBE2A gene

Entrez Gene cytogenetic band: Xq24-q25 Ensembl cytogenetic band: Xq24 HGNC cytogenetic band: Xq24

UBE2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XP118592: (about GC identifiers)

Start:	118,592,527 bp from pter
End:	118,602,409 bp from pter
Size:	9,883 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000023.9 NT_011786.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: UBE2A_HUMAN, P49459 (See protein sequence)

Recommended Name: Ubiquitin-conjugating enzyme E2 A

Size: 152 amino acids; 17315 Da

Subunit: Interacts with RAD18

Secondary accessions: A6NMF5 B2R7R9 Q4TTG1 Q96FX4

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_003327.2 NP_861427.1 NP_861442.1

ENSEMBL proteins:

ENSP00000360624 ENSP00000384285 ENSP00000360613 ENSP00000335027

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant UBE2A Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Enzo Life Sciences proteins for UBE2A
	Recombinant Proteins from Abcam (Rad6)
	Human Recombinant Proteins from Abnova (UBE2A)

OriGene Purified Recombinant Human Proteins (see all 2): UBE2A

Antibodies for UBE2A:

	Invitrogen Antibodies for UBE2A
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for UBE2A
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Rad6), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (UBE2A)
	Novus Biologicals Antibodies for UBE2A

Assays for UBE2A:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Enzo Life Sciences assays for UBE2A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P49459

ProtoNet protein and cluster: P49459

1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes

UniProtKB/Swiss-Prot: UBE2A_HUMAN, P49459

Similarity: Belongs to the ubiquitin-conjugating enzyme family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE2A)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE2A)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_003336

Applied Biosystems Silencer® siRNAs for UBE2A

Sigma-Aldrich siRNA and siRNA Panels for UBE2A

Sigma-Aldrich shRNA Panels and shRNA for UBE2A

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_003336
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_003336
untagged cDNA clones in CMV expression vector (see all 3): NM_003336

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003336

UniProtKB/Swiss-Prot: UBE2A_HUMAN, P49459

Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Required for

postreplication repair of UV-damaged DNA

Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein

N-ubiquityllysine

Enzyme Number (IUBMB): EC 6.3.2.19

Genatlas biochemistry entry for UBE2A:

ubiquitin conjugating enzyme E2A,involved in post replication repair

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ube2a):

growth/size

lethality-prenatal/perinatal

reproductive system

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004842	ubiquitin-protein ligase activity	IEA	--
GO:0016874	ligase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for UBE2A (Your Favorite Gene powered by Ingenuity)

Hypoxia Signaling in the Cardiovascular System
Protein Ubiquitination Pathway

GeneDecks UBE2A for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: UBE2A_HUMAN, P49459

Pathway: Protein modification; protein ubiquitination

Gene Network Central^TM Interacting Genes and Proteins Network for UBE2A

5/21 Interacting proteins for UBE2A (ENSP00000360624³) via UniProtKB, MINT, and/or STRING (see all 21 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TP53	ENSP00000269305³	STRING (score=.969)
MDM2	ENSP00000258149³	STRING (score=.961)
UBA1	ENSP00000338413³	STRING (score=.958)
CDC2	ENSP00000362917³	STRING (score=.955)
UBE3A	ENSP00000232165³	STRING (score=.951)

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006301	postreplication repair	TAS	1559696
GO:0006511	ubiquitin-dependent protein catabolic process	TAS	1559696
GO:0006974	response to DNA damage stimulus	IEA	--
GO:0043687	post-translational protein modification	IEA	--
GO:0051246	regulation of protein metabolic process	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for UBE2A

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE2A)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE2A)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_003336

Sigma-Aldrich siRNA and siRNA Panels for UBE2A

Sigma-Aldrich shRNA Panels and shRNA for UBE2A

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003336 NM_181762 NM_181777

REFSEQ mRNAs for UBE2A gene (3 alternative transcripts):

NM_003336.2 NM_181762.1 NM_181777.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003336 NM_181762 NM_181777

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_003336
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_003336
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_003336

Additional cDNA sequence:

AK223045.1 AK223064.1 AK297696.1 AK301675.1 AK313092.1 BC010175.2 BC042021.1 CR592668.1

CR595604.1 CR598158.1 CR598456.1 CR600075.1 CR603049.1 CR608682.1 CR614387.1 CR614696.1

CR616784.1 CR618296.1 CR621348.1 CR622728.1 D28459.1 M74524.1

20 DOTS entries:

DT.452059 DT.92407072 DT.91959936 DT.100795889 DT.40121076 DT.75112169 DT.121299908 DT.121299914

DT.91789984 DT.95324926 DT.100795884 DT.100795886 DT.100795888 DT.121299884 DT.121299910 DT.91813739

DT.97824937 DT.100758018 DT.91999652 DT.97791444

24/408 AceView cDNA sequences (see all 408 ):

CA424516 AI300485 BE349961 AA594270 AA825629 CB127128 D20353 BM671147

AW205767 AI609766 CR608682 BQ717080 AA747564 CR600075 CR616784 AA804394

CR618296 BQ006384 BM127839 CR592668 CR614696 BM128046 BQ576081 AI087376

highest scoring ESTs for UBE2A:

M74524 AA000982 AA015815 AA029245 AA032037 AA034264 AA043941 AA044203 AA045750 AA045751

Unigene Cluster for UBE2A:

Ubiquitin-conjugating enzyme E2A (RAD6 homolog)

Hs.379466 [show with all ESTs]

Unigene Representative Sequence: BC042021

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2A (see all 7 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3a	·	3b	^	4	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	·	7c	·	7d
SP1:																	-		-				-
SP2:									-								-		-				-
SP3:																	-						-
SP4:																	-		-		-		-
SP5:													-		-		-		-				-

About this scheme

ECgene alternative splicing isoforms for UBE2A

4 Ensembl transcripts including schematic representations:

ENST00000371569 ENST00000404672 ENST00000371558 ENST00000346330

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

UBE2A expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for UBE2A

¹ / ² / ³

5 probe-sets matching UBE2A gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
890_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M74524	1.00	1.00	1.00	1
201898_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI126625	0.80	1.00	0.91	1
201899_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003336	0.60	1.00	0.82	1
201898_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201899_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CGGGACTTCA

SOURCE GeneReport for Unigene cluster: Hs.379466
Expression variation in blood from EXPOLDB for UBE2A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for UBE2A gene from 5/17 species (see all 17 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	UBE2A¹	--	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	95.61(n) 100(a)	492095 XM_549217.2 XP_549217.2
chimpanzee (Pan troglodytes)	UBE2A¹	--	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	99.78(n) 100(a)	737175 XM_001137388.1 XP_001137388.1
rat (Rattus norvegicus)	Ube2a¹	--	ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. more	93.2(n) 100(a)	298317 NM_001013933.1 NP_001013955.1
mouse (Mus musculus)	Ube2a^{1, 5}	X⁵	ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. more^{1, 5}	93.42(n)¹ 100(a)¹	22209¹ NM_019668.3¹ NP_062642.1¹ AF089812⁵ AF383148⁵ (see all 19)
chicken (Gallus gallus)	UBE2A¹	--	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	89.04(n) 100(a)	395672 NM_204865.1 NP_990196.1

About this table Species with no ortholog for UBE2A

ENSEMBL Gene Tree for UBE2A

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for UBE2A gene

UBE2B² UBE2C²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/76 NCBI SNPs in UBE2A are shown (see all 76 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 42)

AB	SNP ID	Valid	Chr X pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2239005^1,2	C,F,H	118597504(+)	`ATATTT/CCTctc`	3	--	ng5¹ int¹		9		EU EA WA NS	606
	rs5910619^1,2	A,C,F	118591854(+)	`TACTCT/CGCCTG`	2	--	ng5¹		5		NS	139
--	rs5909640^1,2	A,C	118602656(+)	`agtggC/Ttcacg`	3	--	ng3¹		0	--	--	--	--
	rs34138874^1,2	C,F	118599448(+)	`ACTACT/CGAACA`	3	--	int¹ ut5¹		5		NS	137
	rs14982^1,2	C	118602293(+)	`TGTCTA/GATGTT`	3	--	ut3¹ ese³		1		MN	184
	rs12863747^1,2	H	118592080(+)	`CCGAAG/AGGGTT`	2	--	ng5¹		4		EU EA WA	418
	rs35570533^1,2	F	118601770(+)	`AAGATC/ATCAGT`	3	--	ut3¹		5		NS	143
	rs34228798^1,2	F	118597969(+)	`GAAGAA/TCTGTG`	3	--	int¹ ng5¹		5		NS	186
	rs35068848^1,2	F	118601826(+)	`GAAGGA/TCTCAG`	3	--	ut3¹		5		NS	143
	rs35826268^1,2	F	118592083(+)	`AAGGGG/ATTGTG`	2	--	ng5¹		5		NS	146

About this table

HapMap Linkage Disequilibrium images for UBE2A (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 312180

1 PharmGKB disease relationship for UBE2A gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872 12730115

About this table

Human Gene Mutation Database: UBE2A

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/23 PubMed articles for UBE2A gene (see all 23 ):

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31. (PubMed id 1559696)^{1, 2, 3} Koken M.H....Hoeijmakers J.H. (1992)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6. (PubMed id 1717990)^{3, 4} Koken M.H.M.... Hoeijmakers J.H.J. (1991)
Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation. (PubMed id 11953320)^{1, 3} Sarcevic B....Sutherland R.L. (2002)
The human RAD18 gene product interacts with HHR6A and HHR6B. (PubMed id 10908344)^{1, 3} Xin H....Wang Z. (2000)
UBE2A, which encodes a ubiquitin-conjugating enzyme, is mutated in a novel X-linked mental retardation syndrome. (PubMed id 16909393)³ Nascimento R.M....Vianna-Morgante A.M. (2006)
The DNA sequence of the human X chromosome. (PubMed id 15772651)⁴ Ross M.T.... Bentley D.R. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)⁴ Ota T....Sugano S. (2004)
Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response. (PubMed id 12640129)³ Lyakhovich A. and Shekhar M.P. (2003)
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. (PubMed id 12730115)⁷ Ross M.E....Downing J.R. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 7319	HGNC: 12472	AceView: UBE2A	Ensembl:ENSG00000077721	euGenes: HUgn7319
ECgene: UBE2A	H-InvDB: UBE2A

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for UBE2A	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/ube2a/

Licensable Technologies for UBE2A
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for UBE2A:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for UBE2A-related products

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	Millipore Preclinical / Clinical Development Services
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	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
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	"Your Favorite Gene" Pathways		feedback

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	Recombinant Proteins (Rad6)
	Antibodies (Rad6)

	Tagged/untagged cDNA clones
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	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for UBE2A

	Assays/Proteins for UBE2A
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for UBE2A

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UBE2A Gene

protein-coding GIFtS: 68

Aliases &
Descriptions
for UBE2A

Summaries
for UBE2A

Genomic Location
for UBE2A

Proteins
for UBE2A

Protein Domains/
Families
for UBE2A

Gene Function
for UBE2A

Pathways & Interactions
for UBE2A

Drugs & Compounds
for UBE2A

Transcripts
for UBE2A

Expression
for UBE2A

Orthologs
for UBE2A

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for UBE2A

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Medical News
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Services
for UBE2A

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

UBE2A Gene

protein-coding GIFtS: 68

Aliases & Descriptionsfor UBE2A

Summariesfor UBE2A

Genomic Locationfor UBE2A

Proteinsfor UBE2A

Protein Domains/Familiesfor UBE2A

Gene Functionfor UBE2A

Pathways & Interactionsfor UBE2A

Drugs & Compoundsfor UBE2A

Transcriptsfor UBE2A

Expression for UBE2A

Orthologsfor UBE2A

Paralogsfor UBE2A

SNPs/Variantsfor UBE2A

Disorders & Mutationsfor UBE2A

Medical Newsfor UBE2A

Publicationsfor UBE2A

Search for UBE2A

Genome Databases showing UBE2A

Other Databases showing UBE2A

Specialized Databases showing UBE2A

Licensable Technologiesfor UBE2A

Servicesfor UBE2A

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for UBE2A

Summaries
for UBE2A

Genomic Location
for UBE2A

Proteins
for UBE2A

Protein Domains/
Families
for UBE2A

Gene Function
for UBE2A

Pathways & Interactions
for UBE2A

Drugs & Compounds
for UBE2A

Transcripts
for UBE2A

Expression
for UBE2A

Orthologs
for UBE2A

Paralogs
for UBE2A

SNPs/Variants
for UBE2A

Disorders & Mutations
for UBE2A

Medical News
for UBE2A

Publications
for UBE2A

Licensable Technologies
for UBE2A

Services
for UBE2A