UBD Gene
protein-coding GIFtS : 57
GCID: GC06 M029525
ubiquitin D
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Aliasesfor UBD gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Ubiquitin D 1 2 UBD-32 FAT101 2 3 5 Diubiquitin3 Ubiquitin-Like Protein FAT102 3 Diubiquitin3 GABBR12
Export aliases for UBD gene to outside databases Previous GC identifers: GC06M029580 GC06M029294 GC06M029632 GC06M029633 GC06M029634 GC06Mc29667 GC06M029330
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Summariesfor UBD gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: UBD_HUMAN, O15205 Function : Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads totheir degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) summary
for UBD : GABAB receptors are metabotropic G-protein-coupled receptors responsible for mediating the inhibitoryeffects of GABA alongside ionotropic GABAA and GABAC receptors. They exist as heterodimers of GABAB1 andGABAB2 subunits and the presence of both subunits is required for receptor function. When GABAB1 isexpressed alone it is non-functional and is not transported to the cell membrane. The GABAB1 subunit isresponsible for binding GABA while the GABAB2 subunit interacts with the G protein. The two subunitsinteract allosterically, GABA increases coupling of GABAB2 to G proteins and GABAB2 increases agonistbinding to GABAB1. GABAB receptors are coupled to Ca2+ and K+ channels. Gene Wiki entry for UBD (Ubiquitin D)
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Genomic Viewsfor UBD gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the UBD gene promoter: Nkx3-1 SREBP-1c Egr-1 E47 SREBP-1b Egr-2 Max SREBP-1a Hand1 c-Myc Other transcription factors Search SABiosciences Chromatin IP Primers for UBD Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBD
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p22.1 HGNC cytogenetic band: 6p21.3 UBD Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 6 GeneLoc Exon Structure
GeneLoc location for GC06M029525: view genomic region
(about GC identifiers )
Start:
29,523,292 bp from pter
End:
29,527,702 bp from pter
Size:
4,411 bases
Orientation:
minus strand
6 alternative locations : Chr 6-,ALT_REF_LOCI_5 29,438,024-29,442,337 Chr 6-,ALT_REF_LOCI_3 29,523,343-29,538,694 Chr 6-,ALT_REF_LOCI_2 29,519,995-29,563,496 Chr 6-,ALT_REF_LOCI_4 29,446,050-29,450,364 Chr 6-,ALT_REF_LOCI_1 29,523,504-29,536,118 Chr 6-,ALT_REF_LOCI_6 29,523,310-29,563,205
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Proteinsfor UBD gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: UBD_HUMAN, O15205 (See
protein sequence )Recommended Name: Ubiquitin D Size : 165 amino acids; 18473 Da
Subunit : Interact directly with the 26S proteasome. The interaction with NUB1L vie the N-terminal ubiquitin domainfacilitates the linking of UBD-conjugated target protein to the proteasome complex and accelerates its own degradation and that of its conjugates. Interacts with the spindle checkpoint protein MAD2L1 during mitosis. Present in aggresomes of proteasome inhibited cells. Interacts with HDAC6 under proteasome impairment conditions. Forms a thioester with UBA6 in cells stimulated with tumor necrosis factor-alpha (TNFa) and interferon-gamma (IFNg)
Subcellular location : Nucleus. Cytoplasm (By similarity). Note=Accumulates in aggresomes under proteasome inhibitionconditions
Miscellaneous : Common types of chronic kidney disease are associated with tubulointerstitial up-regulation of FAT10.FAT10 may mediate NF-kappa-B activation and may promote tubulointerstitial inflammation in chronic kidney diseases
Secondary accessions : B0UZT6 Q5STL2 Q5SUK2 Q96EC7Explore the universe of human proteins at neXtProt for UBD: NX_O15205 Post-translational modifications:
Can be acetylated1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_O15205 UBD Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_006389.2 ENSEMBL proteins: ENSP00000366249 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
UBD for ontologies About GeneDecksing UBD Antibody Products: Assay Products for UBD:
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Protein
Domains / Familiesfor UBD gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
UBD for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry O15205 ProtoNet protein and cluster: O15205
1 Blocks protein family : IPB000626 Ubiquitin domain UniProtKB/Swiss-Prot: UBD_HUMAN, O15205 Similarity : Contains 2 ubiquitin-like domains
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Functionfor UBD gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: UBD_HUMAN, O15205 Function : Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads totheir degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) Induction : Rapidly degraded by the proteasome. Cell-cycle regulation with highest expression during the S-phase (atprotein level). Induced during dendritic cell maturation. Negatively regulated by p53/TP53. High levels in various gastrointestinal and gynecological cancer cells. Induced in RTECs in common renal diseases including diabetic nephropathy (DN), IgA nephropathy (IgAN), and hypertensive nephrosclerosis (HN), as well as in hepatocellular carcinoma (HCC) and during HIVAN. Inducible by the proinflammatory cytokines IFNG/IFN-gamma and TNF in cancers of liver and colon. Repressed by NUB1L (at protein level)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UBD (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UBDOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: UBD (NM_006398 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBD Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UBD
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBD
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
UBD for ontologies About GeneDecksing Animal Models: Mouse knock-out Ubd tm1Smwe for UBD 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ubd) :
UBD for phenotypes About GeneDecksing
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Pathways & Interactionsfor UBD gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways  - 5/18 super-pathways (see all 18 ) About this table See pathways by source Super-pathway contained gene-specific pathways 1 BRCA1 Pathway 2 WNT Signaling 3 Ubiquitin-Proteasome Dependent Proteolysis 4 TRAF Pathway 5 Remodeling of Adherens Junctions
Pathway sources See GeneCards unified pathways Show all pathways 1 EMD Millipore Pathway for UBD 5/17 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for UBD (see all 17 )
UBD for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UBD STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)5/16 Interacting proteins for UBD (O15205 3 ENSP00000366249 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 16 )About this table Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12 ): About this table
UBD for ontologies About GeneDecksing
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Drugs & Compoundsfor UBD gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Compounds for UBD available from Tocris Bioscience About this table Compound Action
CAS
# 2-Hydroxysaclofen Selective GABAB antagonist, more potent than saclofen (Cat. No. 0246) [117354-64-0] CGP 55845 hydrochloride Potent, selective GABAB antagonist [149184-22-5] SCH 50911 Selective, competitive, orally active GABAB antagonist [160415-07-6] CGP 52432 Potent, selective GABAB antagonist [139667-74-6]
Search CenterWatch for drugs/clinical trials and news about UBD
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Transcriptsfor UBD gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for UBD gene: NM_006398.3 Unigene Cluster for UBD:
Ubiquitin D Hs.44532 [show with all ESTs ] Unigene Representative Sequence: NM_006398 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000377050 (uc003nmo.3 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UBD (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UBDOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: UBD (NM_006398 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBD Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UBD
Additional cDNA sequence: AF123050.1 AK311914.1 BC012472.1 Y12653.1
6 DOTS entries : DT.100645165 DT.112373
DT.121390472 DT.95359346 DT.92324520 DT.95368176 24/255 AceView cDNA sequences (see all 255 ):
BX111922 AJ012185 AJ012186 AU280038 W07715 BX107545 AL119755 BX090421 BX280913 NM_021904 CF552729 BG818076 AW090617 AW264022 BM680931 BM661640 AL602784 BM710330 AJ225028 BF476724 CB054344 BM726324 NM_021903 AJ012288 GeneLoc Exon Structure
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Expression for UBD gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section UBD expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ATTTTTACTA
About this image UBD expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See UBD Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for UBD SOURCE GeneReport for Unigene cluster: Hs.44532 UniProtKB/Swiss-Prot: UBD_HUMAN, O15205 Tissue specificity : Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in thereticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland SABiosciences Custom PCR Arrays for UBD Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for UBDBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat UBD QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat UBD QIAGEN QuantiFast Probe-based Assays in human , mouse , rat UBD In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBD
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Orthologsfor UBD gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBD gene from 2/13 species (see all 13 ) About this table
ENSEMBL Gene Tree for UBD (if available)TreeFam Gene Tree for UBD (if available)
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Paralogsfor UBD gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for UBD gene UBB 2 ISG15 2 UBC 2 UBBP4 2 5 SIMAP similar genes for UBD using alignment to 2 protein entries: UBD_HUMAN (see all proteins ):UBC DKFZp434K0435 UBB UBBP4 FAU
UBD for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for UBD PGOHUM00000243119
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Genomic Variantsfor UBD gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 6 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for UBD (29523292 - 29527702 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for UBD 2 CNVs : 3598 36504 Human Gene Mutation Database (HGMD) : UBD SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing UBD
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Disorders
/ Diseasesfor UBD gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
UBD for disorders About GeneDecksing
OMIM gene information: 606050
OMIM disorders : --20/26 diseases for UBD (see all 26 ): About MalaCards severe acute respiratory syndrome systemic lupus erythematosus polycystic kidney disease lupus erythematosus inflammatory bowel disease nephrosclerosis multiple sclerosis intrahepatic cholangiocarcinoma kidney disease nephropathy celiac disease cystitis cholangiocarcinoma hepatitis b hepatocellular carcinoma gastric cancer colorectal cancer adenoma hepatitis hypertension 2 Novoseek disease relationships for UBD gene About this table
Human Genome Epidemiology (HuGE) Navigator: UBD (7 documents) Export disorders for UBD gene to outside databases
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Publicationsfor UBD gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for UBD gene, integrated from 9 sources (see all 92 ): (articles sorted by number of sources associating them with UBD) Utopia : connect your pdf to the dynamic world of online information
Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells. (PubMed id 9368598) 1 , 2 , 3 Bates E.E.M.... Lebecque S. (1997) Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers. (PubMed id 12730673) 1 , 2 , 9 Lee C.G....Lee L.A. (2003) A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. (PubMed id 10200259) 1 , 2 , 9 Liu Y.-C....Weissman S.M. (1999) FAT10 plays a role in the regulation of chromosomal stability. (PubMed id 16495226) 1 , 2 , 9 Ren J....Lee C.G. (2006) The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition. (PubMed id 19033385) 1 , 2 , 9 Kalveram B....Groettrup M. (2008) Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. (PubMed id 16495380) 1 , 2 , 9 Ross M.J....Klotman P.E. (2006) The ubiquitin-like protein FAT10 mediates NF-kappaB a ctivation. (PubMed id 19959714) 1 , 2 Gong P....Ross M.J. (2010) Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. (PubMed id 19028597) 1 , 2 Ebstein F....Kloetzel P.M. (2009) FAT10: a novel mediator of Vpr-induced apoptosis in h uman immunodeficiency virus-associated nephropathy. (PubMed id 19726511) 1 , 2 Snyder A....Ross M.J. (2009) FAT10 level in human gastric cancer and its relation with mutant p53 level, lymph node metastasis and TNM staging. (PubMed id 19437562) 1 , 2 Ji F....Chen Y.L. (2009)
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Specialized Databases showing UBD gene (According to PharmGKB ,
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PharmGKB entry for UBD Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for UBD gene: Search GeneIP for patents involving UBD GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor UBD gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for UBD OriGene shRNA RFP for UBD OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for UBD OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for UBD OriGene Protein Over-expression Lysate for UBD Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for UBD OriGene 3'-UTR Clone for UBD OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UBD OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UBD Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for UBD OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for UBD OriGene Custom Protein Services for UBD OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBD QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing UBD QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBD QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat UBD QIAGEN QuantiFast Probe-based Assays in human , mouse , rat UBD QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat UBD
Tocris compounds for UBD
Recombinant Protein for UBD
UBD Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBD
Search ThermoFisher Antibodies for UBD
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UBD
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