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Aliases for UBAP2L Gene

Aliases for UBAP2L Gene

  • Ubiquitin Associated Protein 2-Like 2 3
  • Protein NICE-4 3 4
  • Ubiquitin-Associated Protein 2-Like 3
  • KIAA0144 4
  • NICE-4 3
  • NICE4 4

External Ids for UBAP2L Gene

Summaries for UBAP2L Gene

GeneCards Summary for UBAP2L Gene

UBAP2L (Ubiquitin Associated Protein 2-Like) is a Protein Coding gene. An important paralog of this gene is UBAP2.

Gene Wiki entry for UBAP2L Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBAP2L Gene

Genomics for UBAP2L Gene

Genomic Location for UBAP2L Gene

Start:
154,220,172 bp from pter
End:
154,271,510 bp from pter
Size:
51,339 bases
Orientation:
Plus strand

Genomic View for UBAP2L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBAP2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBAP2L Gene

Regulatory Elements for UBAP2L Gene

Proteins for UBAP2L Gene

  • Protein details for UBAP2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14157-UBP2L_HUMAN
    Recommended name:
    Ubiquitin-associated protein 2-like
    Protein Accession:
    Q14157
    Secondary Accessions:
    • B4E0U8
    • Q5VU75
    • Q5VU76
    • Q9BTU3
    • Q9UGL2
    • Q9UGL3
    • Q9UGL4
    • Q9UGL5

    Protein attributes for UBAP2L Gene

    Size:
    1087 amino acids
    Molecular mass:
    114535 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAB65100.2; Type=Frameshift; Positions=1085; Evidence={ECO:0000305};

    Alternative splice isoforms for UBAP2L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UBAP2L Gene

Proteomics data for UBAP2L Gene at MOPED

Post-translational modifications for UBAP2L Gene

No data available for DME Specific Peptides for UBAP2L Gene

Domains for UBAP2L Gene

Protein Domains for UBAP2L Gene

UniProtKB/Swiss-Prot:

UBP2L_HUMAN
Domain:
  • Contains 1 UBA domain.:
    • Q14157
genes like me logo Genes that share domains with UBAP2L: view

No data available for Gene Families for UBAP2L Gene

Function for UBAP2L Gene

Gene Ontology (GO) - Molecular Function for UBAP2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 19945174
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with UBAP2L: view

Phenotypes for UBAP2L Gene

MGI mutant phenotypes for UBAP2L:
inferred from 1 alleles
GenomeRNAi human phenotypes for UBAP2L:
genes like me logo Genes that share phenotypes with UBAP2L: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for UBAP2L Gene

Localization for UBAP2L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UBAP2L Gene COMPARTMENTS Subcellular localization image for UBAP2L gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for UBAP2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005671 colocalizes_with Ada2/Gcn5/Ada3 transcription activator complex IDA 18838386
GO:0031519 PcG protein complex IDA 25185265
genes like me logo Genes that share ontologies with UBAP2L: view

Pathways for UBAP2L Gene

SuperPathways for UBAP2L Gene

No Data Available

Gene Ontology (GO) - Biological Process for UBAP2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007339 binding of sperm to zona pellucida IMP 19945174
GO:0061484 hematopoietic stem cell homeostasis IGI 25185265
genes like me logo Genes that share ontologies with UBAP2L: view

No data available for Pathways by source for UBAP2L Gene

Transcripts for UBAP2L Gene

Unigene Clusters for UBAP2L Gene

Ubiquitin associated protein 2-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UBAP2L Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20a ·
SP1: - - -
SP2: - - - -
SP3:
SP4:
SP5: - -
SP6: -
SP7:
SP8: -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:

ExUns: 20b · 20c ^ 21a · 21b · 21c · 21d ^ 22a · 22b · 22c ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c ^ 26 ^ 27a · 27b ^ 28a · 28b · 28c ^ 29 ^ 30 ^ 31a · 31b
SP1: - - - - - - - - -
SP2: - - - - -
SP3: - - - - - - - - - -
SP4: - - - - - - - -
SP5:
SP6:
SP7: - - - - - - -
SP8:
SP9: - - -
SP10: - -
SP11: - - - -
SP12:
SP13:
SP14: - - - - -
SP15:
SP16: -
SP17:

Relevant External Links for UBAP2L Gene

GeneLoc Exon Structure for
UBAP2L
ECgene alternative splicing isoforms for
UBAP2L

Expression for UBAP2L Gene

mRNA expression in normal human tissues for UBAP2L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UBAP2L Gene

SOURCE GeneReport for Unigene cluster for UBAP2L Gene Hs.490551

mRNA Expression by UniProt/SwissProt for UBAP2L Gene

Q14157-UBP2L_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expressions with UBAP2L: view

Orthologs for UBAP2L Gene

This gene was present in the common ancestor of animals.

Orthologs for UBAP2L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBAP2L 36
  • 99.82 (n)
  • 99.91 (a)
UBAP2L 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UBAP2L 36
  • 96.18 (n)
  • 98.66 (a)
UBAP2L 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UBAP2L 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ubap2l 16
Ubap2l 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia UBAP2L 37
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Atp8b2 36
  • 94.44 (n)
  • 98.11 (a)
chicken
(Gallus gallus)
Aves UBAP2L 37
  • 88 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UBAP2L 37
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.5318 36
ubap2l 36
  • 71.46 (n)
  • 77.12 (a)
zebrafish
(Danio rerio)
Actinopterygii ubap2l 37
  • 61 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta lig 37
  • 17 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 28 (a)
ManyToMany
CSA.1157 37
  • 36 (a)
ManyToMany
Species with no ortholog for UBAP2L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UBAP2L Gene

ENSEMBL:
Gene Tree for UBAP2L (if available)
TreeFam:
Gene Tree for UBAP2L (if available)

Paralogs for UBAP2L Gene

Paralogs for UBAP2L Gene

Selected SIMAP similar genes for UBAP2L Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with UBAP2L: view

Variants for UBAP2L Gene

Sequence variations from dbSNP and Humsavar for UBAP2L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs715737 -- 154,264,094(-) GAGAT(A/G)TCTGA intron-variant
rs1194580 -- 154,247,009(-) GATGT(A/C)GTTAA intron-variant
rs1194581 -- 154,243,605(-) cacac(A/G)cctgt intron-variant
rs1194595 -- 154,267,944(-) ccatt(A/G)cactc intron-variant
rs1194596 -- 154,265,907(+) ACTAG(A/G)CCTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UBAP2L Gene

Variant ID Type Subtype PubMed ID
nsv2954 CNV Insertion 18451855
esv2672763 CNV Deletion 23128226
nsv521887 CNV Gain 19592680

Relevant External Links for UBAP2L Gene

HapMap Linkage Disequilibrium report
UBAP2L

Disorders for UBAP2L Gene

Relevant External Links for UBAP2L

Human Genome Epidemiology (HuGE) Navigator
UBAP2L
genes like me logo Genes that share disorders with UBAP2L: view

No data available for UniProtKB/Swiss-Prot for UBAP2L Gene

Publications for UBAP2L Gene

  1. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8590280) Nagase T. … Nomura N. (DNA Res. 1995) 2 3 4
  2. Identification of human epidermal differentiation complex (EDC)- encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. (PMID: 11230159) Marenholz I. … Mischke D. (Genome Res. 2001) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3 4
  5. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PMID: 15144186) Brill L.M. … Peters E.C. (Anal. Chem. 2004) 3 4

Products for UBAP2L Gene

  • antibodies-online peptides for UBAP2L
  • antibodies-online antibodies for UBAP2L
  • antibodies-online kits for UBAP2L

Sources for UBAP2L Gene

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