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Aliases for UBAP1L Gene

Aliases for UBAP1L Gene

  • Ubiquitin Associated Protein 1-Like 2 3
  • UBAP-1L 3 4

External Ids for UBAP1L Gene

Previous GeneCards Identifiers for UBAP1L Gene

  • GC15M065387

Summaries for UBAP1L Gene

GeneCards Summary for UBAP1L Gene

UBAP1L (Ubiquitin Associated Protein 1-Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBAP1L Gene

Genomics for UBAP1L Gene

Genomic Location for UBAP1L Gene

Chromosome:
15
Start:
65,092,760 bp from pter
End:
65,115,197 bp from pter
Size:
22,438 bases
Orientation:
Minus strand

Genomic View for UBAP1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBAP1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBAP1L Gene

No data available for Regulatory Elements for UBAP1L Gene

Proteins for UBAP1L Gene

  • Protein details for UBAP1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F5GYI3-UBA1L_HUMAN
    Recommended name:
    Ubiquitin-associated protein 1-like
    Protein Accession:
    F5GYI3

    Protein attributes for UBAP1L Gene

    Size:
    381 amino acids
    Molecular mass:
    40592 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBAP1L Gene

Proteomics data for UBAP1L Gene at MOPED

Post-translational modifications for UBAP1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UBAP1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBAP1L Gene

Domains & Families for UBAP1L Gene

Protein Domains for UBAP1L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

F5GYI3

UniProtKB/Swiss-Prot:

UBA1L_HUMAN :
  • Contains 1 UMA domain.
Domain:
  • Contains 1 UMA domain.
genes like me logo Genes that share domains with UBAP1L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for UBAP1L Gene

Function for UBAP1L Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBAP1L Gene

Localization for UBAP1L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for UBAP1L Gene

Pathways & Interactions for UBAP1L Gene

SuperPathways for UBAP1L Gene

No Data Available

Interacting Proteins for UBAP1L Gene

Gene Ontology (GO) - Biological Process for UBAP1L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for UBAP1L Gene

Drugs & Compounds for UBAP1L Gene

No Compound Related Data Available

Transcripts for UBAP1L Gene

Unigene Clusters for UBAP1L Gene

Ubiquitin associated protein 1-like:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBAP1L Gene

No ASD Table

Relevant External Links for UBAP1L Gene

GeneLoc Exon Structure for
UBAP1L
ECgene alternative splicing isoforms for
UBAP1L

Expression for UBAP1L Gene

mRNA expression in normal human tissues for UBAP1L Gene

mRNA differential expression in normal tissues according to GTEx for UBAP1L Gene

This gene is overexpressed in Brain - Cerebellum (x5.0) and Brain - Cerebellar Hemisphere (x4.7).

Protein differential expression in normal tissues from HIPED for UBAP1L Gene

This gene is overexpressed in Ovary (28.7), Adrenal (15.7), and Gallbladder (13.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for UBAP1L Gene



SOURCE GeneReport for Unigene cluster for UBAP1L Gene Hs.659256

genes like me logo Genes that share expression patterns with UBAP1L: view

Protein tissue co-expression partners for UBAP1L Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for UBAP1L Gene

Orthologs for UBAP1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for UBAP1L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia UBAP1L 35
  • 79.95 (n)
  • 76.25 (a)
dog
(Canis familiaris)
Mammalia UBAP1L 35
  • 83.02 (n)
  • 79.25 (a)
UBAP1L 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm514 35
  • 75.57 (n)
  • 71.12 (a)
Gm514 16
Gm514 36
  • 61 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia UBAP1L 35
  • 99.13 (n)
  • 99.74 (a)
UBAP1L 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ubap1l 35
  • 78.08 (n)
  • 74.12 (a)
oppossum
(Monodelphis domestica)
Mammalia UBAP1L 36
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 13 (a)
ManyToMany
chicken
(Gallus gallus)
Aves PDCD7 35
  • 60.43 (n)
  • 53.54 (a)
UBAP1L 36
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UBAP1L 36
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ubap1l 35
  • 53.19 (n)
  • 45.98 (a)
zebrafish
(Danio rerio)
Actinopterygii CABZ01068819.1 36
  • 29 (a)
OneToMany
UBAP1L (1 of 2) 36
  • 29 (a)
OneToMany
Species with no ortholog for UBAP1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UBAP1L Gene

ENSEMBL:
Gene Tree for UBAP1L (if available)
TreeFam:
Gene Tree for UBAP1L (if available)

Paralogs for UBAP1L Gene

No data available for Paralogs for UBAP1L Gene

Variants for UBAP1L Gene

Sequence variations from dbSNP and Humsavar for UBAP1L Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs2289437 -- 65,094,740(+) GGGGA(C/T)AGAGG intron-variant, nc-transcript-variant
rs2414875 -- 65,097,915(+) ATCAG(C/T)GATGA intron-variant, nc-transcript-variant
rs2919337 -- 65,093,374(+) GGGCC(A/C/G)CACCT intron-variant
rs2919338 -- 65,105,010(+) caaat(A/G)aaaaa intron-variant
rs2919339 -- 65,106,282(+) AGAGT(C/T)GAGTC utr-variant-5-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for UBAP1L Gene

Variant ID Type Subtype PubMed ID
nsv904308 CNV Loss 21882294
nsv1570 CNV Insertion 18451855

Variation tolerance for UBAP1L Gene

Gene Damage Index Score: 2.42; 42.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for UBAP1L Gene

HapMap Linkage Disequilibrium report
UBAP1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBAP1L Gene

Disorders for UBAP1L Gene

Relevant External Links for UBAP1L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UBAP1L
genes like me logo Genes that share disorders with UBAP1L: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBAP1L Gene

Publications for UBAP1L Gene

  1. UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes. (PMID: 20448139) de Souza R.F. … Aravind L. (Bioinformatics 2010) 67
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for UBAP1L Gene

Sources for UBAP1L Gene

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