UBALD1 Gene
protein-coding GIFtS: 35
GCID: GC16M004656
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UBA-Like Domain Containing 1(Previous names: family with sequence similarity 100, member A)
(Previous symbol: FAM100A)
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Aliases
for UBALD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| UBA-Like Domain Containing 11 2 | | FAM100A1 2 3 | | Family With Sequence Similarity 100, Member A1 2 | | Protein FAM100A2 | | UBA-Like Domain-Containing Protein 12 |
Export aliases for UBALD1 gene to outside databases |
Summaries
for UBALD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for UBALD1 Gene: 
UBALD1 (UBA-like domain containing 1) is a protein-coding gene. An important paralog of this gene is UBALD2.
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Genomic Views
for UBALD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.2 NT_010393.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for UBALD1
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBALD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBALD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3UBALD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M004656: view genomic region
(about GC identifiers)
Start:
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4,658,884 bp from pter |
End:
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4,665,028 bp from pter |
Size:
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6,145 bases |
Orientation:
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minus strand |
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Proteins
for UBALD1 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
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UniProtKB/Swiss-Prot: UBAD1_HUMAN, Q8TB05 (See
protein sequence)Recommended Name: UBA-like domain-containing protein 1 Size: 177 amino acids; 18954 Da
Secondary accessions: Q71MF6Alternative splicing: 2 isoforms: Q8TB05-1 Q8TB05-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBALD1: NX_Q8TB05
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q8TB05
UBALD1 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : --
REFSEQ proteins: NP_660296.1
ENSEMBL proteins: ENSP00000465706 ENSP00000466361 ENSP00000467671 ENSP00000283474 ENSP00000464725 ENSP00000465041 ENSP00000466404 ENSP00000465745 ENSP00000465847
Human Recombinant Protein Products for UBALD1:
UBALD1 Antibody Products:
Assay Products for UBALD1: |
Protein
Domains /
Families
for UBALD1 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| 1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q8TB05 ProtoNet protein and cluster: Q8TB05 UniProtKB/Swiss-Prot: UBAD1_HUMAN, Q8TB05Similarity: Belongs to the UBALD family
UBALD1 for domains About GeneDecksing
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Function
for UBALD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
UBALD1 for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for UBALD1:
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for UBALD1 | |  | Search LifeMap BioReagents cell lines for UBALD1 | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBALD1 |
Pathways & Interactions
for UBALD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBALD1
5 Interacting proteins for UBALD1 (Q8TB053) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for UBALD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBALD1 (UBAD1)
Search CenterWatch for drugs/clinical trials and news about UBALD1 / UBAD1
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Transcripts
for UBALD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for UBALD1 gene: NM_145253.2 Unigene Cluster for UBALD1: UBA-like domain containing 1 Hs.513313 [show with all ESTs]Unigene Representative Sequence: AK1236369 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000590891 ENST00000590965 ENST00000591401 ENST00000283474(uc002cwx.2)
ENST00000591897 ENST00000588691 ENST00000587615 ENST00000587649 ENST00000591113
Additional mRNA sequence: AF370434.1 AK055785.1 AK056747.1 AK123636.1 BC008681.1 BC012018.1 BC025327.1 BC040160.1 BC062534.1 8 DOTS entries: DT.91979584 DT.91702998 DT.95269094 DT.95320502 DT.100693593 DT.102824868 DT.102824870 DT.75154845 24/121 AceView cDNA sequences (see all 121): AA701309 AI801861 AA679059 AI926801 BM785544 F37812 BQ669438 BE856719 CR608937 BM673763 AW015675 BC008681 CB044437 BE777940 BM555223 BQ777776 AI417947 AA932365 BC012018 BQ962361 BC062534 BM465955 BM765099 BM743754
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for UBALD1 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
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| SP1: | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UBALD1
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Expression
for UBALD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBALD1 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image
Genevestigator expression for UBALD1
SOURCE GeneReport for Unigene cluster: Hs.513313
SABiosciences Custom PCR Arrays for UBALD1
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for UBALD1
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat UBALD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBALD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBALD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBALD1 |
Orthologs
for UBALD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for UBALD1 gene from 3/8 species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ubald15
Fam100a1 |
family with sequence similarity 100, member A1, 5 |
90.67(n)1
93.14(a)1 |
|
16 (2.48 cM)5
2077401 NM_145359.21 NP_663334.11
48747785 |
chicken
(Gallus gallus) |
Aves |
FAM100A1 |
family with sequence similarity 100, member A |
68.47(n)
64.19(a) |
|
416661 XM_414958.3 XP_414958.3 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.147522 |
Transcribed sequences |
74.14(n) |
|
CF998871.1 |
ENSEMBL Gene Tree for UBALD1 (if available)
TreeFam Gene Tree for UBALD1 (if available) |
Paralogs
for UBALD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBALD1 gene
- UBALD22
2 SIMAP similar genes for UBALD1 using alignment to 6 protein entries: UBAD1_HUMAN (see all proteins):FAM100A UBALD2
UBALD1 for paralogs About GeneDecksing
|
Genomic Variants
for UBALD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBALD1 (4658884 - 4665028 bp)
Structural Variations
Database of Genomic Variants (DGV) variations for UBALD1: --
| | SABiosciences Cancer Mutation PCR Assays |
| | SeqTarget long-range PCR primers for resequencing UBALD1 |
|
Disorders
/ Diseases
for UBALD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for UBALD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBALD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with UBALD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for UBALD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing UBALD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBALD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBALD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBALD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBALD1 gene:
Search GeneIP for patents involving UBALD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBALD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBALD1 | | | QIAGEN SeqTarget long-range PCR primers for resequencing UBALD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBALD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBALD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBALD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBALD1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBALD1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for UBALD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBALD1 |
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