UBALD1 Gene
protein-coding GIFtS: 34
GCID: GC16M004656
|
|
UBA-Like Domain Containing 1(Previous names: family with sequence similarity 100, member A)
(Previous symbol: FAM100A)
| |
Aliases
for UBALD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
TryGeneCards Plus |
| Aliases |
|---|
| UBA-Like Domain Containing 11 2 | | FAM100A1 2 3 | | Family With Sequence Similarity 100, Member A1 2 | | Protein FAM100A2 | | UBA-Like Domain-Containing Protein 12 |
Export aliases for UBALD1 gene to outside databases |
Summaries
for UBALD1 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
TryGeneCards Plus |
GeneCards Summary for UBALD1 Gene:
UBALD1 (UBA-like domain containing 1) is a protein-coding gene. An important paralog of this gene is UBALD2.
|
Genomic Views
for UBALD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | RefSeq DNA sequence:- NC_000016.10 NC_018927.2 NT_010393.17
Regulatory elements:
 Search for regulatory transcription factor binding sites for UBALD1
Other transcription factors
Search Chromatin IP Primers for UBALD1
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBALD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3UBALD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M004656: view genomic region
(about GC identifiers)
Start:
|
4,658,884 bp from pter |
End:
|
4,665,028 bp from pter |
Size:
|
6,145 bases |
Orientation:
|
minus strand |
|
Proteins
for UBALD1 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
TryGeneCards Plus |
UniProtKB/Swiss-Prot: UBAD1_HUMAN, Q8TB05 (See
protein sequence)Recommended Name: UBA-like domain-containing protein 1 Size: 177 amino acids; 18954 Da
Secondary accessions: Q71MF6Alternative splicing: 2 isoforms: Q8TB05-1 Q8TB05-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBALD1: NX_Q8TB05
Explore proteomics data for UBALD1 at MOPED
See UBALD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB
REFSEQ proteins: NP_660296.1
ENSEMBL proteins: ENSP00000465706 ENSP00000466361 ENSP00000467671 ENSP00000283474 ENSP00000464725 ENSP00000465041 ENSP00000466404 ENSP00000465745 ENSP00000465847
UBALD1 Human Recombinant
Protein Products:UBALD1 Antibody
Products:UBALD1 Assay Products: |
Domains /
Families
for UBALD1 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | 1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q8TB05 ProtoNet protein and cluster: Q8TB05 UniProtKB/Swiss-Prot: UBAD1_HUMAN, Q8TB05Similarity: Belongs to the UBALD family
UBALD1 for domains About GeneDecksing
|
Function
for UBALD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
TryGeneCards Plus |
Gene Ontology (GO): 1 molecular function term: About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
UBALD1 for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for UBALD1:
Animal Models:
Inhib. RNA
Products: |  | OriGene RNAi products in human, mouse, rat for UBALD1
| | | Predesigned siRNA for gene silencing in human, mouse, rat UBALD1 |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for UBALD1 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for UBALD1  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBALD1 |
Localization
for UBALD1 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
About This Section
TryGeneCards Plus | -- |
Pathways & Interactions
for UBALD1 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
About This Section
TryGeneCards Plus |
Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UBALD1
Interactions:
Search GeneGlobe Interaction Network for UBALD1
5 Interacting proteins for UBALD1 (Q8TB053) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for UBALD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
TryGeneCards Plus |
 Browse compounds at ApexBio
 Browse Tocris compounds for UBALD1 (UBAD1)
|
Transcripts
for UBALD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
About This Section
TryGeneCards Plus |
REFSEQ mRNAs for UBALD1 gene: NM_145253.2 Unigene Cluster for UBALD1: UBA-like domain containing 1 Hs.513313 [show with all ESTs]Unigene Representative Sequence: AK1236369 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000590891 ENST00000590965 ENST00000591401 ENST00000283474(uc002cwx.2)
ENST00000591897 ENST00000588691 ENST00000587615 ENST00000587649 ENST00000591113
Inhib. RNA
Products: | | OriGene RNAi products in human, mouse, rat for UBALD1
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat UBALD1 |
Additional mRNA sequence: AF370434.1 AK055785.1 AK056747.1 AK123636.1 BC008681.1 BC012018.1 BC025327.1 BC040160.1 BC062534.1 8 DOTS entries: DT.91979584 DT.91702998 DT.95269094 DT.95320502 DT.100693593 DT.102824868 DT.102824870 DT.75154845 Selected AceView cDNA sequences (see all 121): BM673763 AI926801 AW015675 BQ669438 CR608937 BE856719 F37812 AI801861 BM785544 AA679059 AA701309 AA482549 AI961676 BM677675 NM_145253 BQ061245 BQ887900 AI417947 BM765099 AA285012 BQ962361 BI962821 BC025327 AF447881
GeneLoc Exon Structure
Selected Alternative Splicing Database (ASD) splice patterns (SP) for UBALD1 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
|
| SP1: | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UBALD1
|
Expression
for UBALD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
TryGeneCards Plus |
UBALD1 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image UBALD1 Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  About this image
SOURCE GeneReport for Unigene cluster: Hs.513313
Custom PCR Arrays for UBALD1
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for UBALD1
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat UBALD1 | | | QuantiTect SYBR Green Assays in human, mouse, rat UBALD1 | | | QuantiFast Probe-based Assays in human, mouse, rat UBALD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBALD1 |
Orthologs
for UBALD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
TryGeneCards Plus |
This gene was present in the common ancestor of chordates.
Orthologs for UBALD1 gene from Selected species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ubald11 , 5 |
family with sequence similarity 100, member A5
UBA-like domain containing 11 |
90.67(n)1
93.14(a)1 |
|
16 (2.48 cM)5
2077401 NM_145359.21 NP_663334.11
48747785 |
chicken
(Gallus gallus) |
Aves |
FAM100A1 |
family with sequence similarity 100, member A |
68.14(n)
66.18(a) |
|
416661 XM_414958.4 XP_414958.4 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.147522 |
Transcribed sequences |
74.14(n) |
|
CF998871.1 |
ENSEMBL Gene Tree for UBALD1 (if available)
TreeFam Gene Tree for UBALD1 (if available) |
Paralogs
for UBALD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | Paralogs for UBALD1 gene
- UBALD22
2 SIMAP similar genes for UBALD1 using alignment to 6 protein entries: UBAD1_HUMAN (see all proteins):FAM100A UBALD2
UBALD1 for paralogs About GeneDecksing
|
Genomic Variants
for UBALD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
TryGeneCards Plus |
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBALD1 (4658884 - 4665028 bp)
Structural Variations
Database of Genomic Variants (DGV) variations for UBALD1: --
| | Site Specific Mutation Identification with PCR Assays |
| | SeqTarget long-range PCR primers for resequencing UBALD1 |
|
Disorders
/ Diseases
for UBALD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
TryGeneCards Plus | -- |
Publications
for UBALD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
TryGeneCards Plus |
PubMed articles for UBALD1 gene integrated from 10 sources:
(articles sorted by number of sources associating them with UBALD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
|
External Searches for UBALD1 gene (in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
TryGeneCards Plus |
|
Genome Databases showing UBALD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
TryGeneCards Plus |
|
Other Databases showing UBALD1 gene
(According to HUGE)
About This Section
TryGeneCards Plus | -- |
Specialized Databases showing UBALD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section
TryGeneCards Plus |
| Name | Description |
| PharmGKB entry for UBALD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
TryGeneCards Plus | Patent Information for UBALD1 gene:
Search GeneIP for patents involving UBALD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBALD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
TryGeneCards Plus |
 | |
 |
| | | | |
 |
 |
|  | Block miRNA regulation of human, mouse, rat UBALD1 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing UBALD1 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBALD1 | | Predesigned siRNA for gene silencing in human, mouse, rat UBALD1 | | | QuantiFast Probe-based Assays in human, mouse, rat UBALD1 | | QuantiTect SYBR Green Assays in human, mouse, rat UBALD1 | | | Custom PCR Arrays for UBALD1 | | Search Chromatin IP Primers for UBALD1 | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat UBALD1 | | Search GeneGlobe Interaction Network for UBALD1 | | | Search Regulatory tfbs for UBALD1 |
| |
 |  |  |  | |
| | | |  |  |  |
 | | | | |
 |
 |
 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBALD1 |
| |  |  |  |  | | | Search ThermoFisher Antibodies for UBALD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBALD1 |
| | |  |  | | |
|
|
|
GeneCards Homepage -
Last full update: 7 May 2014 -
Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014
View Random Gene
|
Category
|
|
|
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2014
, Weizmann Institute of Science. All Rights Reserved.
Version: 3.12.142 28 July 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4
|
