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UBA7 Gene

protein-coding GIFtS: 54

GC03M049818

ubiquitin-like modifier activating enzyme 7
(Previous name: ubiquitin-activating enzyme E1-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: UBE1L)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
D8 ^¹, ², ³
MGC12713 ^²
UBA1B ^¹, ²
UBE1L ^², ³
UBE2 ^¹, ², ³

Descriptions
UBA1, ubiquitin-activating enzyme E1 homolog B ^²
UBA7, ubiquitin-activating enzyme E1 ^²
Ubiquitin-activating enzyme 7 ^³
Ubiquitin-activating enzyme E1 homolog ^³
ubiquitin-activating enzyme E1-like ^¹, ²
ubiquitin-activating enzyme E1-related protein ^²
ubiquitin-activating enzyme-2 ^²
ubiquitin-like modifier activating enzyme 7 ^²

External Ids
HGNC: 12471¹
Entrez Gene: 7318²
UniProtKB: P41226³
Ensembl: ENSG00000182179⁷

Search outside databases for aliases for UBA7 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for UBA7:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting

abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes

of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and

ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating

enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia

(PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic

leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene

15 protein. [provided by RefSeq]

UniProtKB/Swiss-Prot: UBA7_HUMAN, P41226

Function: Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and

thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an

ubiquitin-E1 thioester and free AMP

Gene Wiki entry for UBA7 (UBE1L)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21 Ensembl cytogenetic band: 3p21.31 HGNC cytogenetic band: 3p21

UBA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M049818: (about GC identifiers)

Start:	49,817,642 bp from pter
End:	49,826,395 bp from pter
Size:	8,754 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000003.10 NT_022517.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: UBA7_HUMAN, P41226 (See protein sequence)

Recommended Name: Ubiquitin-like modifier-activating enzyme 7

Size: 1012 amino acids; 111694 Da

Subunit: Monomer (By similarity). Binds and is involved in the conjugation of G1P2/ISG15

Miscellaneous: There are two active sites within the E1 molecule, allowing it to accommodate two

ubiquitin moieties at a time, with a new ubiquitin forming an adenylate intermediate as the

previous one is transferred to the thiol site

Secondary accessions: Q9BRB2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_003326.2

ENSEMBL proteins:

ENSP00000333266

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Ube1L)
	Human Recombinant Proteins from Abnova (UBE1L)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

Antibodies for UBA7:

	Invitrogen Antibodies for UBA7
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for UBA7
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Ube1L), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (UBE1L)
	Novus Biologicals Antibodies for UBA7

Assays for UBA7:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P41226

ProtoNet protein and cluster: P41226

2 Blocks protein families:

IPB000011 Ubiquitin-activating enzyme

IPB000594 UBA/THIF-type NAD/FAD binding fold

UniProtKB/Swiss-Prot: UBA7_HUMAN, P41226

Similarity: Belongs to the ubiquitin-activating E1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBA7)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE1L)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003335

Applied Biosystems Silencer® siRNAs for UBA7

Sigma-Aldrich siRNA and siRNA Panels for UBA7

Sigma-Aldrich shRNA Panels and shRNA for UBA7

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for UBA7
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003335
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003335
untagged cDNA clone in CMV expression vector: NM_003335

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003335

UniProtKB/Swiss-Prot: UBA7_HUMAN, P41226

Function: Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and

thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an

ubiquitin-E1 thioester and free AMP

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Uba7):

cellular

normal

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016874	ligase activity	IEA	--
GO:0019782	ISG15 activating enzyme activity	IDA	16428300

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: UBA7_HUMAN, P41226

Pathway: Protein modification; protein ubiquitination

Gene Network Central^TM Interacting Genes and Proteins Network for UBA7

5/9 Interacting proteins for UBA7 (ENSP00000333266³ P41226²) via UniProtKB, MINT, and/or STRING (see all 9 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ISG15	P05161²	STRING (score=.997) MINT-68321
HERC5	ENSP00000264350³	STRING (score=.928)
CCND1	ENSP00000227507³	STRING (score=.867)
UBC	ENSP00000344818³	STRING (score=.842)
UBE2A	ENSP00000360624³	STRING (score=.753)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006464	protein modification process	IDA	16428300
GO:0008152	metabolic process	IEA	--
GO:0019941	modification-dependent protein catabolic process	IEA	--
GO:0032020	ISG15-protein conjugation	IDA	16428300

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for UBA7

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBA7)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE1L)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003335

Sigma-Aldrich siRNA and siRNA Panels for UBA7

Sigma-Aldrich shRNA Panels and shRNA for UBA7

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003335

REFSEQ mRNAs for UBA7 gene:

NM_003335.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003335

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003335
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003335
                                 untagged cDNA clone in CMV expression vector: NM_003335

Additional cDNA sequence:

BC006378.2 BT007026.1 L13852.1

11 DOTS entries:

DT.445469 DT.92430180 DT.95243263 DT.40108845 DT.95113689 DT.100787258 DT.40194929 DT.100787255

DT.95113692 DT.97844492 DT.97864605

24/213 AceView cDNA sequences (see all 213 ):

AL044030 BT007026 AL547566 AW576378 BQ073643 BF917672 BQ215515 CD364579

CA866495 CD516564 CA866761 CA422452 BF848533 BF935874 AL044026 CK430594

CA426107 CD370845 CF453713 BF847898 BM671696 BC006378 BX482902 BQ214509

Unigene Cluster for UBA7:

Ubiquitin-like modifier activating enzyme 7

Hs.16695 [show with all ESTs]

Unigene Representative Sequence: NM_003335

GeneLoc Exon Structure

5/14 Alternative Splicing Database (ASD) splice patterns (SP) for UBA7 (see all 14 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14a	·	14b	^	15a	·	15b	^	16a	·	16b	·	16c	^	17	^
SP1:																													-														-
SP2:
SP3:																																									-		-		-		-		-		-
SP4:																			-
SP5:

ExUns:	18	^	19a	·	19b	·	19c	·	19d	^	20	^	21a	·	21b	^	22	^	23a	·	23b	^	24	^	25	^	26	^	27
SP1:
SP2:
SP3:	-		-		-		-		-		-		-
SP4:
SP5:											-

About this scheme

ECgene alternative splicing isoforms for UBA7

1 Ensembl transcript including schematic representation:

ENST00000333486

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

UBA7 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for UBA7

¹ / ²

5 probe-sets matching UBA7 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1294_at²	U95-A	1	1.00	1.00	1.00	1.00	--	--	--	--	--
203281_s_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
1294_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
203281_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1294_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks UBA7 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGGACTTTGT

SOURCE GeneReport for Unigene cluster: Hs.16695
UniProtKB/Swiss-Prot: UBA7_HUMAN, P41226
Tissue specificity: Expressed in a variety of normal and tumor cell types, but is reduced in lung
cancer cell lines

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for UBA7 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	UBA7¹	--	ubiquitin-like modifier activating enzyme 7	84.06(n) 81.25(a)	608118 XM_845452.1 XP_850545.1
chimpanzee (Pan troglodytes)	UBA7¹	--	ubiquitin-like modifier activating enzyme 7	99.56(n) 99.19(a)	744322 XM_001166289.1 XP_001166289.1
cow (Bos taurus)	UBA7¹	--	ubiquitin-like modifier activating enzyme 7	82.7(n) 77.96(a)	497204 NM_001012284.1 NP_001012284.1
rat (Rattus norvegicus)	Uba7¹	--	ubiquitin-like modifier activating enzyme 7	79.96(n) 74.8(a)	301000 XM_217252.4 XP_217252.3
mouse (Mus musculus)	Uba7⁵ Ube1l¹	9 (60.00 cM)⁵	ubiquitin-like modifier activating enzyme 7⁵ ubiquitin-activating enzyme E1-like¹	80.96(n)¹ 75.79(a)¹	74153¹ NM_023738.3¹ NP_076227.1¹ AF288694⁵ AI894313⁵ (see all 19)

About this table Species with no ortholog for UBA7

ENSEMBL Gene Tree for UBA7

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for UBA7 gene

UBA6² UBA1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/52 NCBI SNPs in UBA7 are shown (see all 52 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 30)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2230149^1,2	C,F,H	49820530(-)	`CTTCCA/GTGTGG`	1	H/R	mis¹		10		MN EU EA WA NA	956
	rs13071187^1,2	C,H	49824429(+)	`GGGCTG/AGAGCA`	1	X/Q	non¹ ese³		4		EU EA WA	416
	rs12486358^1,2	C,H	49823840(+)	`CTGTCC/TGCTTC`	1	R/Q	mis¹ ese³		4		EU EA WA	406
	rs2234386^1,2	H	49820846(-)	`CTCCCC/GTGAAG`	1	L/V	mis¹ ese³		4		EU EA WA	416
--	rs6775384^1,2	C	49828077(+)	`tcccaA/Gagtgc`	1	--	ng3¹		0	--	--	--	--
--	rs11928913^1,2	H	49821856(+)	`CTGGGG/AACACT`	1	S/P	mis¹ ese³		4		EU EA WA	406
	rs2234379^1,2	H	49824324(-)	`GGCCAC/GCCCAG`	1	P/A	mis¹ ese³		4		EU EA WA	412
	rs1799845^1,2	A,C,F,H	49822627(-)	`CTCCCT/CTGCCA`	1	--	int¹		4		EU EA WA	406
	rs1799843^1,2	A,C,F	49824727(-)	`AAGGTC/G/TTGGGA`	1	--	int¹		2		NA	182
--	rs3819325^1,2	A,C	49818727(-)	`CCCCCA/GCCCCC`	1	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for UBA7 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 191325

4 Novoseek disease relationships for UBA7 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
leukemia promyelocytic acute	67.79	2	11891284 (1), 14976209 (1)
cancer lung	36.30	10	19074853 (3), 15520223 (3), 10709110 (2)
cancer	13.83	3	10709110 (1), 14976209 (1)
tumors	0.00	4	19074853 (1), 15520223 (1), 10709110 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/32 PubMed articles for UBA7 gene (see all 32 ):

A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme. (PubMed id 8327486)^{2, 3, 4} Kok K.... Carritt B. (1993)
Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo. (PubMed id 16254333)^{3, 4} Lenschow D.J.... Virgin H.W. IV (2005)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{3, 4} Gevaert K.... Vandekerckhove J. (2003)
Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein. (PubMed id 11157743)^{3, 4} Yuan W. and Krug R.M. (2001)
The genomic structure of the human UBE1L gene. (PubMed id 7734949)^{3, 4} Kok K....Buys C.H.C.M. (1995)
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia. (PubMed id 11891284)^{1, 3} Kitareewan S....Dmitrovsky E. (2002)
Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia. (PubMed id 14976209)^{1, 3} Pitha-Rowe I....Dmitrovsky E. (2004)
UBE1L causes lung cancer growth suppression by targeting cyclin D1. (PubMed id 19074853)^{1, 3} Feng Q....Dmitrovsky E. (2008)
The basis for selective E1-E2 interactions in the ISG15 conjugation system. (PubMed id 18583345)^{1, 3} Durfee L.A....Huibregtse J.M. (2008)
The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines. (PubMed id 10709110)^{1, 3} McLaughlin P.M....Buys C.H. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 7318	HGNC: 12471	AceView: UBE1L	Ensembl:ENSG00000182179	euGenes: HUgn7318
ECgene: UBA7	H-InvDB: UBA7

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for UBA7
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for UBA7:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for UBA7-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for UBA7		Antibodies for UBA7
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for UBA7		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Antibodies for UBA7

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UBA7 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for UBA7

Summaries
for UBA7

Genomic Location
for UBA7

Proteins
for UBA7

Protein Domains/
Families
for UBA7

Gene Function
for UBA7

Pathways & Interactions
for UBA7

Drugs & Compounds
for UBA7

Transcripts
for UBA7

Expression
for UBA7

Orthologs
for UBA7

Paralogs
for UBA7

SNPs/Variants
for UBA7

Disorders & Mutations
for UBA7

Medical News
for UBA7

Publications
for UBA7

Search for UBA7

Genome Databases showing UBA7

Other Databases showing UBA7

Specialized Databases showing UBA7

Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

UBA7 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor UBA7

Summariesfor UBA7

Genomic Locationfor UBA7

Proteinsfor UBA7

Protein Domains/Familiesfor UBA7

Gene Functionfor UBA7

Pathways & Interactionsfor UBA7

Drugs & Compoundsfor UBA7

Transcriptsfor UBA7

Expression for UBA7

Orthologsfor UBA7

Paralogsfor UBA7

SNPs/Variantsfor UBA7

Disorders & Mutationsfor UBA7

Medical Newsfor UBA7

Publicationsfor UBA7

Search for UBA7

Genome Databases showing UBA7

Other Databases showing UBA7

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Licensable Technologiesfor UBA7

Servicesfor UBA7

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for UBA7

Summaries
for UBA7

Genomic Location
for UBA7

Proteins
for UBA7

Protein Domains/
Families
for UBA7

Gene Function
for UBA7

Pathways & Interactions
for UBA7

Drugs & Compounds
for UBA7

Transcripts
for UBA7

Expression
for UBA7

Orthologs
for UBA7

Paralogs
for UBA7

SNPs/Variants
for UBA7

Disorders & Mutations
for UBA7

Medical News
for UBA7

Publications
for UBA7

Licensable Technologies
for UBA7

Services
for UBA7