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UBA52 Gene

protein-coding   GIFtS: 56

GC19P018548
ubiquitin A-52 residue ribosomal protein fusion product 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for UBA52

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CEP52 1, 2, 3
HUBCEP52 1, 2
MGC126879 1, 2
MGC126881 1, 2
MGC57125 1, 2
RPL40 1, 2
UBA80 3
UBCEP1 3
UBCEP2 3
ubiquitin-CEP52 2
Descriptions
60S ribosomal protein L40 2
ribosomal protein L40 2
ubiquitin A-52 residue ribosomal protein fusion product 1 2
ubiquitin and ribosomal protein L40 2
ubiquitin carboxyl extension protein 52 2
ubiquitin-52 amino acid fusion protein 2
External Ids
HGNC: 124581
Entrez Gene: 73112
UniProtKB: P629873
UniProtKB: P629883
Ensembl: ENSG000002219837
Search outside databases for aliases for UBA52 gene

Previous GC identifers: GC19P019176 GC19P019074 GC19P018527 GC19P018545 GC19P018546

Summaries
for UBA52

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for UBA52:
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting
cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of
chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is
synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin
moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin
at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein
(CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided
by RefSeq]

UniProtKB/Swiss-Prot: UBIQ_HUMAN, P62988
Function: Protein modifier which can be covalently attached to target lysines either as a monomer
or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to
their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked
polymer does not lead to proteasomal degradation and may be required for numerous functions,
including maintenance of chromatin structure, regulation of gene expression, stress response,
ribosome biogenesis and DNA repair

Gene Wiki entry for UBA52 (Ubiquitin_A-52_residue_ribosomal_protein_fusion_product_1)

Genomic Location
for UBA52

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the UBA52 gene  

Entrez Gene cytogenetic band: 19p13.1-p12   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.1-p12

UBA52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P018548:     (about GC identifiers)

Start:
 18,543,614 bp from pter
End:
 18,549,270 bp from pter
Size:
 5,657 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000019.8  NT_011295.10  

Proteins
for UBA52

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: RL40_HUMAN, P62987 (See protein sequence)
Recommended Name: 60S ribosomal protein L40  
Size: 52 amino acids; 6181 Da
Miscellaneous: This ribosomal protein is synthesized as a C-terminal extension protein (CEP) of
ubiquitin
Secondary accessions: P14793 Q9BX98 Q9UPK7

UniProtKB/Swiss-Prot: UBIQ_HUMAN, P62988 (See protein sequence)

Recommended Name: Ubiquitin  
Size: 76 amino acids; 8565 Da
Subcellular location: Cytoplasm. Nucleus
Miscellaneous: Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail
repeats, the number of repeats differ between species and strains. In some species there is a
final amino-acid after the last repeat, here in human a Val. Some ubiquitin genes contain a single
copy of ubiquitin fused to a ribosomal protein (either L40 or S27a)
PDB structures from and Proteopedia :
1C3T (3D)    1CMX (3D)    1D3Z (3D)    1F9J (3D)    1FXT (3D)    1G6J (3D)    1GJZ (3D)    1NBF (3D)    
1OGW (3D)    1Q5W (3D)    1S1Q (3D)    1SIF (3D)    1TBE (3D)    1UBI (3D)    1UBQ (3D)    1XD3 (3D)    
1XQQ (3D)    1YX5 (3D)    1YX6 (3D)    1ZGU (3D)    1ZO6 (3D)    2AYO (3D)    2BGF (3D)    2DEN (3D)    
2FUH (3D)    2G45 (3D)    2GBJ (3D)    2GBK (3D)    2GBM (3D)    2GBN (3D)    2GBR (3D)    2HTH (3D)    
2IBI (3D)    2J7Q (3D)    2JF5 (3D)    2JRI (3D)    2JY6 (3D)    2JZZ (3D)    2K25 (3D)    2K6D (3D)    
2K8B (3D)    2K8C (3D)    2NR2 (3D)    2O6V (3D)    2OJR (3D)    2PE9 (3D)    2PEA (3D)    2W9N (3D)    
2Z59 (3D)    2ZCB (3D)    2ZVN (3D)    2ZVO (3D)    3BY4 (3D)    3C0R (3D)    3DVG (3D)    3DVN (3D)    
3EEC (3D)    3EFU (3D)    3EHV (3D)    
Secondary accessions: P02248 P02249 P02250 Q29120 Q6LBL4 Q6LDU5 Q8WYN8 Q91887 Q91888 Q9BWD6 Q9BX98
Q9UEF2 Q9UEG1 Q9UEK8 Q9UPK7

Post-translational modifications:

  • Several types of polymeric chains can be formed, depending on the lysine used for the assembly1


    • REFSEQ proteins (2 alternative transcripts): 
    NP_001029102.1  NP_003324.1  


    ENSEMBL proteins: 
    ENSP00000386142 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant UBA52 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Ubiquitin +1, Ubiquitin)
    Human Recombinant Proteins from Abnova (UBA52)
                  OriGene Purified Recombinant Human Protein: UBA52 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular IEA--
    GO:0005829 cytosol EXP14567916
    GO:0005840 ribosome IEA--
    About this table

    Antibodies for UBA52: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of UBA52
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for UBA52  (Ubiquitin)
    Antibodies from Abcam (Ubiquitin +1, Ubiquitin), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (UBA52)
    Novus Biologicals Antibody for UBA52

    Assays for UBA52: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for UBA52

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5 InterPro domains/families:
     IPR001975 Ribosomal_L40e
     IPR019954 Ubiquitin_CS
     IPR000626 Ubiquitin
     IPR019955 Ubiquitin_supergroup
     IPR019956 Ubiquitin_subgroup


       GeneDecks  UBA52 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P62987
    Graphical View of Domain Structure for InterPro Entry P62988

    ProtoNet protein and cluster: P62987

    UniProtKB/Swiss-Prot: RL40_HUMAN, P62987
    Similarity: Belongs to the ribosomal protein L40e family

    UniProtKB/Swiss-Prot: UBIQ_HUMAN, P62988
    Similarity: Belongs to the ubiquitin family

    Gene Function
    for UBA52

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (UBA52)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (UBA52)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001033930

                  Applied Biosystems Silencer® siRNAs for UBA52

                  Sigma-Aldrich siRNA and siRNA Panels for UBA52  
                         Sigma-Aldrich shRNA for UBA52  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001033930
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001033930
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001033930 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001033930

    UniProtKB/Swiss-Prot: UBIQ_HUMAN, P62988
    Function: Protein modifier which can be covalently attached to target lysines either as a monomer
    or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to
    their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked
    polymer does not lead to proteasomal degradation and may be required for numerous functions,
    including maintenance of chromatin structure, regulation of gene expression, stress response,
    ribosome biogenesis and DNA repair

    Genatlas biochemistry entry for UBA52:
    ubiquitin-ribosomal protein fusion

    1 Gene Ontology (GO) molecular function term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735 structural constituent of ribosome IEA--
    About this table

    Pathways & Interactions
    for UBA52

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    5/19 Millipore Pathways for UBA52 (see all 19 )
     DNA damage ATM/ATR regulation of G1/S checkpoint
     Meiosis
     Proteolysis Putative SUMO-1 pathway
     Proteolysis Putative ubiquitin pathway
     Immune response IL-1 signaling pathway

       GeneDecks  UBA52 for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for UBA52):
     hsa03010 Ribosome

       GeneDecks  UBA52 for the pathways selected above  
    About GeneDecksing

    5/485 Interacting proteins for UBA52 (P629881, 2 P629871, 2) via UniProtKB, MINT, and/or STRING (see all 485 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K3Q997592MINT-48457 MINT-48457
    RNF11Q9Y3C52MINT-60882 MINT-60882
    TNFRSF1AP194382MINT-49342 MINT-49342
    TP53P046371, 2EBI-413034, EBI-366083 MINT-4051326 MINT-4304004 MINT-4054804 MINT-4304143 MINT-6801380 MINT-6615153 MINT-6541035 MINT-6799774 MINT-7013815 MINT-4052207 MINT-5114741 EBI-413034, EBI-366083 MINT-4051326 MINT-4304004 MINT-4054804 MINT-4304143 MINT-6801380 MINT-6615153 MINT-6541035 MINT-6799774 MINT-7013815 MINT-4052207 MINT-5114741
    MDM2Q009871, 2EBI-413034, EBI-389668 MINT-6801380 MINT-6823761 MINT-6801709 MINT-7013831 MINT-4304119 MINT-6799770 EBI-413034, EBI-389668 MINT-6801380 MINT-6823761 MINT-6801709 MINT-7013831 MINT-4304119 MINT-6799770
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006414 translational elongation EXP15189156
    GO:0006464 protein modification process TAS2581967
    About this table

    Drugs & Compounds
    for UBA52

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for UBA52

    Transcripts
    for UBA52

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (UBA52)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (UBA52)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001033930

                  Sigma-Aldrich siRNA and siRNA Panels for UBA52  
                         Sigma-Aldrich shRNA for UBA52  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001033930  NM_003333  

    REFSEQ mRNAs for UBA52 gene (2 alternative transcripts): 

    NM_001033930.1   NM_003333.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001033930  NM_003333  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001033930
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001033930
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001033930 

    Additional cDNA sequence: 

    AF348700.1 AF545864.1 AK057790.1 AK314717.1 BC101830.1 BC101832.1 BC143668.1 CR604171.1 
    CR605557.1 CR624915.1 X56998.1 X56999.1 Y00361.1 

    24/54 DOTS entries (see all 54 ):

    DT.100834067  DT.100701381  DT.91674003  DT.91770700  DT.91786700  DT.100045216  DT.100701383  DT.100701386 
    DT.95085246  DT.99955604  DT.453583  DT.95159168  DT.91770707  DT.95159231  DT.97775328  DT.401373 
    DT.121499143  DT.95211950  DT.100771856  DT.121499141  DT.121499113  DT.121499107  DT.95159124  DT.100701390 

    24/1424 AceView cDNA sequences (see all 1424 ):

    H13978 BM852498 AA304272 AJ711859 F28571 BG105455 BU192119 BX438962 
    BQ674407 CB134727 BF971004 BE670402 CA946856 F23551 CB137602 CB124676 
    BM463452 AA331302 BQ677516 F29553 AA360211 AJ713557 F29931 F27349 

    highest scoring ESTs for UBA52:

    AA244240 AA292179 AA311225 AA344926 AA457207 AA470556 AA480532 AA482878 AA488095 AA526839 

    Unigene Cluster for UBA52:

    Ubiquitin A-52 residue ribosomal protein fusion product 1
    Hs.5308  [show with all ESTs]
    Unigene Representative Sequence: NM_001033930


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000408928  

    Expression
    for UBA52

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    UBA52 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for UBA52

    1 / 2 / 3

    4 probe-sets matching UBA52 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    58604_s_at2, 3 U95-B 1 1.00 1.00 0.78 0.58 AI302762 0.80 1.00 0.91 1

    		57828_at2, 3 U95-C 2 0.81 0.89 0.25 1.43 AI857945 0.60 1.00 0.82 1

    		221700_s_at2, 3 U133-A 2 1.00 0.95 -- -- AF348700 0.80 1.00 0.91 1

    		221700_s_at2 U133Plus2 2 1.00 0.95 -- -- -- -- -- -- --
    GeneDecks  UBA52 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: CAGATCTTTG

    SOURCE GeneReport for Unigene cluster: Hs.5308

    Orthologs
    for UBA52

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for UBA52 gene from 5/27 species (see all 27 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 UBA521   -- ubiquitin A-52 residue ribosomal protein fusion product more 92.71(n)
    100(a)    		 403722  XM_533870.2  XP_533870.2 
    chimpanzee
    (Pan troglodytes)    		 UBA521   -- ubiquitin A-52 residue ribosomal protein fusion product more 99.48(n)
    100(a)    		 735674  XM_001135183.1  XP_001135183.1 
    cow
    (Bos taurus)    		 UBA521   -- ubiquitin A-52 residue ribosomal protein fusion product more 92.19(n)
    100(a)    		 615199  NM_001076363.1  NP_001069831.1 
    rat
    (Rattus norvegicus)    		 Uba521   -- ubiquitin A-52 residue ribosomal protein fusion product more 89.58(n)
    100(a)    		 64156  NM_031687.2  NP_113875.1 
    mouse
    (Mus musculus)    		 Uba525
    OTTMUSG000000044111    		 8 (33.50 cM)5
    		 ubiquitin A-52 residue ribosomal protein fusion product more5
    predicted gene, OTTMUSG000000044111    		 90.36(n)1
    100(a)1    		 6665861  XM_984767.21  XP_989861.11 
     AF1184025  AK0187265  (see all 14)
    About this table        Species with no ortholog for UBA52

    ENSEMBL Gene Tree for UBA52

    Paralogs
    for UBA52

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for UBA52 gene
    UBB2  ENSG000001892512  UBC2  

    SNPs/Variants
    for UBA52

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/97 NCBI SNPs in UBA52 are shown (see all 97 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 29)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 19 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs22836161,2
    		A,C,F,H18543495(+) CCACAC/ACCGGA 2 -- ng5112Minor allele frequency- A:0.32EA MN EU WA NS 1942
    rs65541,2
    		A,C,F,H18546964(+) AAGGTT/GGTTCT 2 -- ut3124Minor allele frequency- G:0.32MN EA CSAM NA EU WA NS 3170
    --
    rs72585731,2
    		A,C,F18547587(+) agtctC/Tgctct 2 -- ut315Minor allele frequency- T:0.47NS 186
    --
    rs72540041,2
    		A,C,F18547621(+) gcgcaA/Gtctcg 2 -- ut315Minor allele frequency- G:0.49NS 186
    --
    rs116722971,2
    		C,F,H18547810(+) CTTGGC/TCTCCC 2 -- ut319Minor allele frequency- T:0.15EU EA WA NS 604
    rs104250181,2
    		A,C,F18548175(+) AATCAC/TAAGGT 2 -- ut315Minor allele frequency- T:0.33NS 176
    --
    rs104126961,2
    		A,C,F18548997(+) GTTGGC/TGGGAC 2 -- ut315Minor allele frequency- T:0.02NS 184
    --
    rs126089251,2
    		C,F18548533(+) gtggcG/Tcagtc 2 -- ut315Minor allele frequency- T:0.47NS 176
    rs284854481,2
    		C,F18549115(+) TGAAGG/AAAGAA 2 -- ut315Minor allele frequency- A:0.01NS 182
    --
    rs104124581,2
    		C,F18548849(+) ttgcaC/Gtgggt 2 -- ut315Minor allele frequency- G:0.02NS 172
    About this table

    HapMap Linkage Disequilibrium images for UBA52 (up to first 250kb)

    Disorders & Mutations
    for UBA52

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 191321

    Medical News
    for UBA52

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for UBA52

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/59 PubMed articles for UBA52 gene (see all 59 ):

    Search for UBA52

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing UBA52

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 7311 HGNC: 12458 AceView: UBA52 Ensembl:ENSG00000221983 euGenes: HUgn7311
    ECgene: UBA52 H-InvDB: UBA52

    Other Databases showing UBA52

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing UBA52

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    		   --

    Licensable Technologies
    for UBA52

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for UBA52

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for UBA52:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for UBA52-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for UBA52 Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for UBA52 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (UBA52)
     Antibodies (UBA52)
     Chimera RNAi (UBA52)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Antibodies & Assays for UBA52  (Ubiquitin)

     Recombinant Proteins
    (Ubiquitin +1, Ubiquitin)
     Antibodies (Ubiquitin +1, Ubiquitin)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for UBA52




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for UBA52

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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