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Aliases for UAP1L1 Gene

Aliases for UAP1L1 Gene

  • UDP-N-Acetylglucosamine Pyrophosphorylase 1 Like 1 2 3
  • EC 2.7.7.23 63
  • EC 2.7.7.27 63
  • EC 2.7.7.- 4
  • EC 2.7.7 63

External Ids for UAP1L1 Gene

Previous GeneCards Identifiers for UAP1L1 Gene

  • GC09P135329
  • GC09P137248
  • GC09P139091
  • GC09P139971
  • GC09P109431

Summaries for UAP1L1 Gene

GeneCards Summary for UAP1L1 Gene

UAP1L1 (UDP-N-Acetylglucosamine Pyrophosphorylase 1 Like 1) is a Protein Coding gene. Among its related pathways are Metabolism and Amino sugar and nucleotide sugar metabolism. GO annotations related to this gene include nucleotidyltransferase activity. An important paralog of this gene is UAP1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UAP1L1 Gene

Genomics for UAP1L1 Gene

Regulatory Elements for UAP1L1 Gene

Genomic Location for UAP1L1 Gene

Start:
137,077,492 bp from pter
End:
137,084,539 bp from pter
Size:
7,048 bases
Orientation:
Plus strand

Genomic View for UAP1L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UAP1L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UAP1L1 Gene

Proteins for UAP1L1 Gene

  • Protein details for UAP1L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3KQV9-UAP1L_HUMAN
    Recommended name:
    UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
    Protein Accession:
    Q3KQV9
    Secondary Accessions:
    • A2AMJ8
    • Q5SPZ2
    • Q69YQ3
    • Q6ZR38

    Protein attributes for UAP1L1 Gene

    Size:
    507 amino acids
    Molecular mass:
    57030 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI06036.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAH10651.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=EAW88343.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for UAP1L1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UAP1L1 Gene

Proteomics data for UAP1L1 Gene at MOPED

Post-translational modifications for UAP1L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UAP1L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains for UAP1L1 Gene

Protein Domains for UAP1L1 Gene

Graphical View of Domain Structure for InterPro Entry

Q3KQV9

UniProtKB/Swiss-Prot:

UAP1L_HUMAN :
  • Q3KQV9
Family:
  • Belongs to the UDPGP type 1 family.
genes like me logo Genes that share domains with UAP1L1: view

No data available for Gene Families for UAP1L1 Gene

Function for UAP1L1 Gene

Enzyme Numbers (IUBMB) for UAP1L1 Gene

Gene Ontology (GO) - Molecular Function for UAP1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070569 uridylyltransferase activity IEA --
genes like me logo Genes that share ontologies with UAP1L1: view

Phenotypes for UAP1L1 Gene

GenomeRNAi human phenotypes for UAP1L1:
genes like me logo Genes that share phenotypes with UAP1L1: view

No data available for Molecular function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for UAP1L1 Gene

Localization for UAP1L1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UAP1L1 Gene COMPARTMENTS Subcellular localization image for UAP1L1 gene
Compartment Confidence
cytosol 3
nucleus 2
cytoskeleton 1
extracellular 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for UAP1L1 Gene

Pathways for UAP1L1 Gene

genes like me logo Genes that share pathways with UAP1L1: view

Pathways by source for UAP1L1 Gene

Interacting Proteins for UAP1L1 Gene

Gene Ontology (GO) - Biological Process for UAP1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with UAP1L1: view

Transcripts for UAP1L1 Gene

Unigene Clusters for UAP1L1 Gene

UDP-N-acteylglucosamine pyrophosphorylase 1-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UAP1L1 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1:
SP2:
SP3:
SP4: -

Relevant External Links for UAP1L1 Gene

GeneLoc Exon Structure for
UAP1L1
ECgene alternative splicing isoforms for
UAP1L1

Expression for UAP1L1 Gene

mRNA expression in normal human tissues for UAP1L1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UAP1L1 Gene

SOURCE GeneReport for Unigene cluster for UAP1L1 Gene Hs.142076

genes like me logo Genes that share expressions with UAP1L1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for UAP1L1 Gene

Orthologs for UAP1L1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UAP1L1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UAP1L1 35
  • 99.74 (n)
  • 99.8 (a)
UAP1L1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UAP1L1 35
  • 85.43 (n)
  • 84.03 (a)
UAP1L1 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 82 (a)
OneToMany
-- 36
  • 83 (a)
OneToMany
-- 36
  • 85 (a)
OneToMany
UAP1L1 35
  • 85.02 (n)
  • 84.69 (a)
mouse
(Mus musculus)
Mammalia Uap1l1 35
  • 83 (n)
  • 83.4 (a)
Uap1l1 16
Uap1l1 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UAP1L1 36
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Uap1l1 35
  • 83 (n)
  • 83.4 (a)
chicken
(Gallus gallus)
Aves UAP1L1 35
  • 72.87 (n)
  • 70.85 (a)
UAP1L1 36
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UAP1L1 36
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia uap1l1 35
  • 69.82 (n)
  • 67.2 (a)
zebrafish
(Danio rerio)
Actinopterygii uap1l1 35
  • 66.2 (n)
  • 65.86 (a)
uap1l1 36
  • 65 (a)
OneToOne
zgc56509 35
fruit fly
(Drosophila melanogaster)
Insecta mmy 36
  • 47 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C36A4.4 36
  • 35 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes QRI1 36
  • 38 (a)
OneToMany
Species with no ortholog for UAP1L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UAP1L1 Gene

ENSEMBL:
Gene Tree for UAP1L1 (if available)
TreeFam:
Gene Tree for UAP1L1 (if available)

Paralogs for UAP1L1 Gene

Paralogs for UAP1L1 Gene

Selected SIMAP similar genes for UAP1L1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with UAP1L1: view

Variants for UAP1L1 Gene

Sequence variations from dbSNP and Humsavar for UAP1L1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1105834 -- 137,077,096(+) GGGAT(C/T)TCTCG upstream-variant-2KB
rs1122444 - 137,080,081(+) TAAAG(C/T)CGCTA reference, missense
rs1141177 -- 137,084,360(+) tagta(A/G)agatg utr-variant-3-prime
rs1962024 -- 137,081,303(-) AATGG(C/T)GGAAA intron-variant
rs2049039 -- 137,081,050(+) GTGAC(C/T)GTCGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UAP1L1 Gene

Variant ID Type Subtype PubMed ID
nsv469918 CNV Loss 18288195
nsv894387 CNV Gain 21882294
esv2422220 CNV Deletion 17116639
dgv8412n71 CNV Loss 21882294
dgv8415n71 CNV Loss 21882294
dgv8416n71 CNV Loss 21882294
nsv524322 CNV Loss 19592680
nsv894469 CNV Loss 21882294
dgv8423n71 CNV Loss 21882294
nsv894502 CNV Loss 21882294
nsv894503 CNV Loss 21882294
nsv894506 CNV Gain 21882294
dgv8425n71 CNV Loss 21882294
dgv8428n71 CNV Loss 21882294
nsv894521 CNV Loss 21882294
nsv894550 CNV Gain 21882294
dgv8437n71 CNV Gain 21882294
dgv8438n71 CNV Loss 21882294
dgv8439n71 CNV Loss 21882294
dgv8440n71 CNV Loss 21882294
nsv894570 CNV Loss 21882294
dgv8441n71 CNV Loss 21882294
dgv8442n71 CNV Loss 21882294
dgv8443n71 CNV Loss 21882294
nsv831761 CNV Loss 17160897
dgv8445n71 CNV Loss 21882294
dgv8446n71 CNV Loss 21882294
nsv894589 CNV Loss 21882294
esv1002686 CNV Gain 20482838
nsv527575 CNV Loss 19592680
nsv825183 CNV Gain 20364138

Relevant External Links for UAP1L1 Gene

HapMap Linkage Disequilibrium report
UAP1L1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UAP1L1 Gene

Disorders for UAP1L1 Gene

No disorders were found for UAP1L1 Gene.

No data available for UniProtKB/Swiss-Prot for UAP1L1 Gene

Publications for UAP1L1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4
  5. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 4

Products for UAP1L1 Gene

Sources for UAP1L1 Gene

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