Aliases for UAP1 Gene
External Ids for UAP1 Gene
Previous HGNC Symbols for UAP1 Gene
Previous GeneCards Identifiers for UAP1 Gene
GeneCards Summary for UAP1 Gene
UAP1 (UDP-N-Acetylglucosamine Pyrophosphorylase 1) is a Protein Coding gene. Diseases associated with UAP1 include hepadnavirus infection. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include carbohydrate binding and UDP-N-acetylglucosamine diphosphorylase activity. An important paralog of this gene is UAP1L1.
UniProtKB/Swiss-Prot for UAP1 Gene
Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P