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U2AF2 Gene

protein-coding GIFtS: 53

GC19P060858

U2 small nuclear RNA auxiliary factor 2
(Previous name: U2 (RNU2) small nuclear RNA auxiliary factor 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
U2AF65 ^¹, ², ³
hU2AF(65) ^³
hU2AF65 ^³

Descriptions
U2 (RNU2) small nuclear RNA auxiliary factor 2 ^¹, ²
U2 auxiliary factor 65 kDa subunit ^³
U2 small nuclear RNA auxiliary factor 2 ^²
U2 small nuclear ribonucleoprotein auxiliary factor (65kD) ^²
U2 snRNP auxiliary factor large subunit ^², ³
splicing factor U2AF 65 kD subunit ^²

External Ids
HGNC: 23156¹
Entrez Gene: 11338²
UniProtKB: P26368³
Ensembl: ENSG00000063244⁷

Search outside databases for aliases for U2AF2 gene

Previous GC identifer: GC19P060857

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for U2AF2:

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein

required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large

subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an

Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of

introns early during spliceosome assembly. Multiple transcript variants have been detected for

this gene, but the full-length natures of only two have been determined to date. [provided by

RefSeq]

UniProtKB/Swiss-Prot: U2AF2_HUMAN, P26368

Function: Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns

early during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the

mRNA is encoded by an intron-less gene

Gene Wiki entry for U2AF2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the U2AF2 gene

Entrez Gene cytogenetic band: 19q13.42 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.43

U2AF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P060858: (about GC identifiers)

Start:	60,857,228 bp from pter
End:	60,877,894 bp from pter
Size:	20,667 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000019.8 NT_011109.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: U2AF2_HUMAN, P26368 (See protein sequence)

Recommended Name: Splicing factor U2AF 65 kDa subunit

Size: 475 amino acids; 53501 Da

Subunit: Interacts with U2AF1L4 (By similarity). Heterodimer with U2AF1. Binds unphosphorylated

SF1. Interacts with SFRS2IP

Subcellular location: Nucleus

PDB structures from and Proteopedia :

1JMT (3D)

1O0P (3D)

1OPI (3D)

1U2F (3D)

2G4B (3D)

2HZC (3D)

2U2F (3D)

Secondary accessions: Q96HC5

Alternative splicing: 2 isoforms: P26368-1 P26368-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001012496.1 NP_009210.1

ENSEMBL proteins:

ENSP00000307863

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (U2AF65)
	Human Recombinant Proteins from Abnova (U2AF2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005681	spliceosome	IDA	9731529

About this table

Antibodies for U2AF2:

	Invitrogen Antibodies for U2AF2
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibody Arrays and Antibodies for U2AF2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (U2AF65), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for U2AF2

Assays for U2AF2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P26368

ProtoNet protein and cluster: P26368

1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

UniProtKB/Swiss-Prot: U2AF2_HUMAN, P26368

Similarity: Belongs to the splicing factor SR family

Similarity: Contains 3 RRM (RNA recognition motif) domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (U2AF2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (U2AF2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001012478

Applied Biosystems Silencer® siRNAs for U2AF2

Sigma-Aldrich siRNA for U2AF2

Sigma-Aldrich shRNA for U2AF2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001012478
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001012478
untagged cDNA clones in CMV expression vector (see all 3): BC008740

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_007279

UniProtKB/Swiss-Prot: U2AF2_HUMAN, P26368

Function: Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns

early during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the

mRNA is encoded by an intron-less gene

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003723	RNA binding	IEA	--
GO:0005515	protein binding	IPI	9447963

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for U2AF2

5/9 Interacting proteins for U2AF2 (P26368^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 9 )
Interactant Interaction Details
GeneCard External ID(s)
ATXN1 P54253¹^,² EBI-742339, EBI-930964 MINT-2869849 MINT-2869830 MINT-2855372 EBI-742339, EBI-930964 MINT-2869849 MINT-2869830 MINT-2855372
PUF60 Q9UHX1¹ EBI-742339, EBI-1053259
RNPS1 Q15287¹ EBI-742339, EBI-395959
U2AF1 Q01081¹ EBI-742339, EBI-632461
ATXN1 P54253¹^,² EBI-742339, EBI-930964 MINT-2869849 MINT-2869830 MINT-2855372 EBI-742339, EBI-930964 MINT-2869849 MINT-2869830 MINT-2855372
About this table
2 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 nuclear mRNA splicing, via spliceosome IC 9731529
GO:0008380 RNA splicing IEA --
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for U2AF2
4 Novoseek chemical compound relationships for U2AF2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
poly u	56.93	3	17188295 (1), 8990179 (1)
pyrimidine	22.61	2	16809543 (2)
atp	1.04	2	1398075 (1), 16376933 (1)
zinc	0.00	1	10606272 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (U2AF2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (U2AF2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001012478

Sigma-Aldrich siRNA for U2AF2

Sigma-Aldrich shRNA for U2AF2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001012478 NM_007279

REFSEQ mRNAs for U2AF2 gene (2 alternative transcripts):

NM_001012478.1 NM_007279.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001012478 NM_007279

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001012478
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001012478
                                 untagged cDNA clones in CMV expression vector (see all 3): BC008740

Additional cDNA sequence:

AB451261.1 AB451387.1 AK311672.1 BC008740.2 BC030574.2 CR609498.1 X64044.1

19 DOTS entries:

DT.316064 DT.102824787 DT.100787781 DT.121432600 DT.86847492 DT.97858884 DT.100015615 DT.100036921

DT.102824788 DT.121432571 DT.121432611 DT.99985196 DT.100036922 DT.121432584 DT.92438055 DT.95071809

DT.121432551 DT.92061826 DT.95130294

24/266 AceView cDNA sequences (see all 266 ):

BX461321 AI056452 BF115888 BE857957 BM768292 BE646566 BC008740 AI915105

AI161317 AA404408 BM720557 AA640188 BF063339 AI743821 BE466369 BE466493

BG333194 BF732390 AI127369 AI762438 AI807465 BC030574 AA620672 AI082328

highest scoring ESTs for U2AF2:

X64044 AA226292 AA228879 AA309119 AA368773 AA417934 AA418112 AA468878 AA505414 AA640188

Unigene Cluster for U2AF2:

U2 small nuclear RNA auxiliary factor 2

Hs.528007 [show with all ESTs]

Unigene Representative Sequence: NM_007279

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for U2AF2

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b
SP1:																							-
SP2:

About this scheme

ECgene alternative splicing isoforms for U2AF2

1 Ensembl transcript including schematic representation:

ENST00000308924

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

U2AF2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for U2AF2

¹ / ² / ³

9 probe-sets matching U2AF2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
77029_at²^{, 3}	U95-E	1	1.00	1.00	0.41	0.21	AW007068	0.80	1.00	0.91	1
32556_at²^{, 3}	U95-A	1	1.00	1.00	0.91	0.76	X64044	1.00	1.00	1.00	1
54740_at²^{, 3}	U95-B	1	0.81	1.00	0.91	1.24	AI590777	0.80	1.00	0.91	1
218381_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_007279	0.60	1.00	0.82	1
218382_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_007279	0.60	1.00	0.82	1
229508_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BF434828	0.60	1.00	0.82	1
218381_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
218382_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
229508_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks U2AF2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CAGGGCCTGA

SOURCE GeneReport for Unigene cluster: Hs.528007
Expression variation in blood from EXPOLDB for U2AF2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for U2AF2 gene from 5/18 species (see all 18 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
cow (Bos taurus)	U2AF2¹	--	U2 small nuclear RNA auxiliary factor 2	93.56(n) 99.79(a)	507895 NM_001075336.1 NP_001068804.1
rat (Rattus norvegicus)	LOC690372¹	--	similar to U2 (RNU2) small nuclear RNA auxiliary factor more	91.79(n) 100(a)	690372 XM_218195.4 XP_218195.3
mouse (Mus musculus)	U2af2⁵	7	U2 small nuclear ribonucleoprotein auxiliary factor more	--	X64587
zebrafish (Danio rerio)	wufb73g02²	--	wufb73g02	78.86(n)	322805 CF347908.1
fruit fly (Drosophila melanogaster)	U2af50¹	--	U2 small nuclear riboprotein auxiliary factor 50	67.49(n) 74.26(a)	32602 NM_057543.3 NP_476891.1

About this table Species with no ortholog for U2AF2

ENSEMBL Gene Tree for U2AF2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for U2AF2 gene

RBM23² RBM39² PUF60²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/98 NCBI SNPs in U2AF2 are shown (see all 98 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 68)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs504850^1,2	A,C,F,H	60857287(-)	`AAGCCA/GCGGGT`	2	--	ut5¹ ese³		9		MN EU EA WA	1016
	rs504003^1,2	A,C,F,H	60857356(-)	`GAGGGG/ATGAAG`	2	--	ut5¹ ese³		4		MN EU EA	482
	rs2280255^1,2	C	60857733(-)	`CGGCTC/TTTTCC`	2	--	ut5¹ ese³		0	--	--	--	--
	rs617073^1,2	A,C,F,H	60872780(-)	`CGCACA/GTCCTC`	2	D/D	syn¹		8		EU EA WA	830
	rs310441^1,2	A,C,F,H,O	60867327(-)	`GAATAA/CCCAGG`	2	--	int¹		7		EU EA WA NA	562
	rs310445^1,2	A,C,F,H,O	60865363(-)	`CAGAGA/GGCATG`	2	--	int¹		11		EU EA WA NA	980
	rs310437^1,2	A,C,F,H,O	60869508(-)	`CTGCAA/GCGGCT`	2	--	int¹		11		EU EA WA NA	982
	rs310442^1,2	A,C,F,H,O	60867226(-)	`CGCAAA/CGCAGG`	2	--	int¹		8		MN EU EA WA NA	744
	rs310443^1,2	A,C,F,H	60867057(-)	`TAGGGT/GAAGCA`	2	--	int¹		4		EU EA WA	418
	rs10420401^1,2	A,C,F,H	60865324(+)	`CTCTTG/CTGTTT`	2	--	int¹		8		EU EA WA NA	636

About this table

HapMap Linkage Disequilibrium images for U2AF2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 191318

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/119 PubMed articles for U2AF2 gene (see all 119 ):

Cloning and domain structure of the mammalian splicing factor U2AF. (PubMed id 1538748)^{1, 2, 3, 4} Zamore P.D.... Green M.R. (1992)
A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer. (PubMed id 11551507)^{1, 3, 4} Kielkopf C.L.... Burley S.K. (2001)
Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)). (PubMed id 10449418)^{1, 3, 4} Ito T.... Yokoyama S. (1999)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. (PubMed id 16097034)^{3, 4} Gevaert K.... Vandekerckhove J. (2005)
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP. (PubMed id 12718882)^{3, 4} Selenko P.... Sattler M. (2003)
Large-scale proteomic analysis of the human spliceosome. (PubMed id 12176931)^{3, 4} Rappsilber J.... Mann M. (2002)
Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly. (PubMed id 10449420)^{3, 4} Wang X....Robinson P.J. (1999)
Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. (PubMed id 9447963)^{3, 4} Zhang W.J. and Wu J.Y. (1998)
Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65. (PubMed id 18842594)^{1, 3} Jenkins J.L....Kielkopf C.L. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 11338	HGNC: 23156	AceView: U2AF2	Ensembl:ENSG00000063244	euGenes: HUgn11338
ECgene: U2AF2	H-InvDB: U2AF2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for U2AF2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for U2AF2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for U2AF2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for U2AF2		Antibodies for U2AF2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for U2AF2		Browse small molecules at Sigma-Aldrich
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U2AF2 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for U2AF2

Summaries
for U2AF2

Genomic Location
for U2AF2

Proteins
for U2AF2

Protein Domains/
Families
for U2AF2

Gene Function
for U2AF2

Pathways & Interactions
for U2AF2

Drugs & Compounds
for U2AF2

Transcripts
for U2AF2

Expression
for U2AF2

Orthologs
for U2AF2

Paralogs
for U2AF2

SNPs/Variants
for U2AF2

Disorders & Mutations
for U2AF2

Medical News
for U2AF2

Publications
for U2AF2

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Genome Databases showing U2AF2

Other Databases showing U2AF2

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Licensable Technologies
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Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

U2AF2 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor U2AF2

Summariesfor U2AF2

Genomic Locationfor U2AF2

Proteinsfor U2AF2

Protein Domains/Familiesfor U2AF2

Gene Functionfor U2AF2

Pathways & Interactionsfor U2AF2

Drugs & Compoundsfor U2AF2

Transcriptsfor U2AF2

Expression for U2AF2

Orthologsfor U2AF2

Paralogsfor U2AF2

SNPs/Variantsfor U2AF2

Disorders & Mutationsfor U2AF2

Medical Newsfor U2AF2

Publicationsfor U2AF2

Search for U2AF2

Genome Databases showing U2AF2

Other Databases showing U2AF2

Specialized Databases showing U2AF2

Licensable Technologiesfor U2AF2

Servicesfor U2AF2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for U2AF2

Summaries
for U2AF2

Genomic Location
for U2AF2

Proteins
for U2AF2

Protein Domains/
Families
for U2AF2

Gene Function
for U2AF2

Pathways & Interactions
for U2AF2

Drugs & Compounds
for U2AF2

Transcripts
for U2AF2

Expression
for U2AF2

Orthologs
for U2AF2

Paralogs
for U2AF2

SNPs/Variants
for U2AF2

Disorders & Mutations
for U2AF2

Medical News
for U2AF2

Publications
for U2AF2

Licensable Technologies
for U2AF2

Services
for U2AF2