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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TYSND1 Gene

protein-coding   GIFtS: 52
GCID: GC10M071897

Trypsin Domain Containing 1

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Trypsin Domain Containing 11 2
Trypsin Domain-Containing Protein 12 3
NET412
Peroxisomal Leader Peptide-Processing Protease2
EC 3.4.21.-3

External Ids:    HGNC: 285311   Entrez Gene: 2197432   Ensembl: ENSG000001565217   OMIM: 6110175   UniProtKB: Q2T9J03   
ORGUL members:         
NONCODE14:n340059      

Export aliases for TYSND1 gene to outside databases

Previous GC identifers: GC10M071244 GC10M071567 GC10M065890


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TYSND1 Gene:
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins
produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also
capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix.
The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative
splicing results in multiple transcript variants for this gene. (provided by RefSeq, Jan 2013)

GeneCards Summary for TYSND1 Gene: 
TYSND1 (trypsin domain containing 1) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with TYSND1 include alzheimer's disease, and retinitis. GO annotations related to this gene include protease binding and identical protein binding.

UniProtKB/Swiss-Prot: TYSD1_HUMAN, Q2T9J0
Function: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a
PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins
involved in the peroxisomal beta-oxidation of fatty acids




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TYSND1 gene promoter:
         AhR   AML1a   Pax-5   AP-1   Arnt   FOXL1   CREB   GATA-6   FOXO4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTYSND1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TYSND1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TYSND1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.1   HGNC cytogenetic band: 10q22.1

TYSND1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TYSND1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M071897:  view genomic region     (about GC identifiers)

Start:
71,897,733 bp from pter      End:
71,906,496 bp from pter
Size:
8,764 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TYSD1_HUMAN, Q2T9J0 (See protein sequence)
Recommended Name: Peroxisomal leader peptide-processing protease  
Size: 566 amino acids; 59309 Da
Subunit: Homodimer. Forms a heterodimer with the C-terminal cleavage product (45 kDa form). Forms a heterodimer
with the N-terminal cleavage product (15 kDa form). Interacts with PEX5. Interacts with LONP2
Subcellular location: Peroxisome
Secondary accessions: Q5SQT4 Q5SQU1 Q8N6H2 Q96AR5
Alternative splicing: 2 isoforms:  Q2T9J0-1   Q2T9J0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TYSND1: NX_Q2T9J0

Explore proteomics data for TYSND1 at MOPED 

Post-translational modifications:

  • UniProtKB: Self-cleavage gives rise to an N-terminal 15-kDa fragment and C-terminal 45-kDa fragment upon import into the
    peroxisomes. The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in
    self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q2T9J0

  • TYSND1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TYSND1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001035363.1  NP_775826.2  

    ENSEMBL proteins: 
     ENSP00000287078   ENSP00000335673  

    Human Recombinant Protein Products for TYSND1: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TYSND1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome IDA--

    TYSND1 for ontologies           About GeneDecksing



    TYSND1 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR009003 Trypsin-like_Pept_dom
     IPR017345 Pept_S1A_Tysnd1
     IPR001254 Peptidase_S1

    Graphical View of Domain Structure for InterPro Entry Q2T9J0

    ProtoNet protein and cluster: Q2T9J0

    UniProtKB/Swiss-Prot: TYSD1_HUMAN, Q2T9J0
    Similarity: Belongs to the peptidase S1B family


    TYSND1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TYSD1_HUMAN, Q2T9J0
    Function: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a
    PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins
    involved in the peroxisomal beta-oxidation of fatty acids

         Enzyme Number (IUBMB): EC 3.4.21.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002020protease binding IPI--
    GO:0003824catalytic activity ----
    GO:0004252serine-type endopeptidase activity IMP--
    GO:0042802identical protein binding IPI--
         
    TYSND1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TYSND1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TYSND1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TYSND1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TYSND1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TYSND1 

    miRNA
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    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate TYSND1 (see all 12):
    hsa-miR-3938 hsa-miR-125a-5p hsa-miR-875-3p hsa-miR-330-5p hsa-miR-627 hsa-miR-1291 hsa-miR-124 hsa-miR-670
    SwitchGear 3'UTR luciferase reporter plasmidTYSND1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TYSND1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TYSND1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/10 Interacting proteins for TYSND1 (Q2T9J03 ENSP000002870784) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATG16L1Q676U53I2D: score=1 
    JOSD2Q8TAC23I2D: score=1 
    ACOX1ENSP000002932174STRING: ENSP00000293217
    CATENSP000002410524STRING: ENSP00000241052
    ECI2ENSP000003547374STRING: ENSP00000354737
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IMP--
    GO:0016485protein processing IMP--
    GO:0031998regulation of fatty acid beta-oxidation IMP--
    GO:0051260protein homooligomerization IDA--

    TYSND1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TYSND1 (TYSD1)

    Search CenterWatch for drugs/clinical trials and news about TYSND1 / TYSD1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TYSND1 gene (2 alternative transcripts): 
    NM_001040273.2  NM_173555.3  

    Unigene Cluster for TYSND1:

    Trypsin domain containing 1
    Hs.533655  [show with all ESTs]
    Unigene Representative Sequence: NM_173555
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000494143 ENST00000287078(uc001jqr.3) ENST00000335494(uc001jqs.3)
    ENST00000479086(uc001jqq.3 uc001jqt.3)

    miRNA
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    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate TYSND1 (see all 12):
    hsa-miR-3938 hsa-miR-125a-5p hsa-miR-875-3p hsa-miR-330-5p hsa-miR-627 hsa-miR-1291 hsa-miR-124 hsa-miR-670
    SwitchGear 3'UTR luciferase reporter plasmidTYSND1 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TYSND1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TYSND1

    Additional mRNA sequence: 

    AK074968.1 BC016840.1 BC030242.1 BC042629.1 BC047424.1 BC111501.1 NR_073580.1 NR_073581.1 
    NR_073582.1 NR_073591.1 NR_073592.1 NR_073593.1 NR_073594.1 NR_073595.1 

    16 DOTS entries:

    DT.95171726  DT.455072  DT.95171724  DT.100776127  DT.75110654  DT.95171723  DT.92422395  DT.121261108 
    DT.121261164  DT.121261040  DT.92001575  DT.100776128  DT.100776130  DT.121261117  DT.91740825  DT.75171099 

    24/150 AceView cDNA sequences (see all 150):

    AA860182 AW188353 CA442516 AI563945 BM553590 BU183732 AA918067 BX340786 
    BM693889 BX282686 BM664638 BM703137 BI829894 AK097697 AI024441 AI377960 
    BI766480 AL713282 BM670951 BM975929 AA953270 BC016840 BF724663 CD671353 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TYSND1 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g
    SP1:                    -     -     -     -           -                                                   
    SP2:                    -     -     -     -                                                               
    SP3:                          -     -     -                 -                                             
    SP4:                          -     -     -                                                               
    SP5:                                -     -                                                               


    ECgene alternative splicing isoforms for TYSND1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TYSND1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCTATTGAA
    TYSND1 Expression
    About this image


    See TYSND1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TYSND1

    SOURCE GeneReport for Unigene cluster: Hs.533655
        SABiosciences Custom PCR Arrays for TYSND1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TYSND1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TYSND1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tysnd11 , 5 trypsin domain containing 11, 5 80.53(n)1
    80(a)1
      10 (32.26 cM)5
    717671  NM_027912.11  NP_082188.11 
     616955145 
    chicken
    (Gallus gallus)
    Aves TYSND11 trypsin domain containing 1 60.42(n)
    49.47(a)
      769373  XM_001232632.2  XP_001232633.2 
    lizard
    (Anolis carolinensis)
    Reptilia TYSND16
    Uncharacterized protein
    45(a)
    1 ↔ 1
    3(51302552-51316471)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.40782 Xenopus laevis transcribed sequences 71.43(n)    48045536 
    zebrafish
    (Danio rerio)
    Actinopterygii tysnd11 trypsin domain containing 1 47.72(n)
    42.97(a)
      561667  NM_001128710.1  NP_001122182.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG35896
    --
    25(a)
    1 ↔ 1
    2R(20671095-20673065)


    ENSEMBL Gene Tree for TYSND1 (if available)
    TreeFam Gene Tree for TYSND1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/277 SNPs in TYSND1 are shown (see all 277)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1145244881,2
    F--71897285(+) ATTAAC/TTTACT 10 -- ds50011Minor allele frequency- T:0.03WA 118
    rs109991551,2
    C,F--71897293(+) ACTGTA/TGAACT 10 -- ds500113Minor allele frequency- N:0.00EA NA CSA WA 576
    rs1930667161,2
    --71897353(+) AGGAAC/TAACCA 10 -- ds50010--------
    rs1854386701,2
    --71897365(+) CCCAGG/TAGTGT 10 -- ds50010--------
    rs354890981,2
    C,F--71897385(+) GCCCCG/ATGTTT 10 -- ds50014Minor allele frequency- A:0.03NA WA 242
    rs1883566051,2
    --71897514(+) TCAGCC/TGGGTG 10 -- ds50010--------
    rs42930191,2
    C,F,A--71897517(+) GCCGGG/TTGTCC 10 -- ds50017Minor allele frequency- T:0.38WA NA CSA EA 366
    rs1157599691,2
    C,F--71897748(+) TTACCG/AGTTTA 10 -- ut31 nc-transcript-variant3Minor allele frequency- A:0.05WA NA EA 358
    rs761477161,2
    C,F--71897823(+) GGAAGG/CAGTGC 10 -- ut31 nc-transcript-variant3Minor allele frequency- C:0.08WA NA EA 358
    rs1917910401,2
    --71897871(+) GGAAGC/TGCCAG 10 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for TYSND1 (71897733 - 71906496 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TYSND1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv7054CNV Insertion18451855
    esv32737CNV Gain+Loss17666407

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611017    OMIM disorders: --

    2 diseases for TYSND1:    About MalaCards
    alzheimer's disease    retinitis

    1 disease from the University of Copenhagen DISEASES database for TYSND1:
    Zellweger syndrome

    TYSND1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): TYSND1
    Human Genome Epidemiology (HuGE) Navigator: TYSND1 (2 documents)

    Export disorders for TYSND1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TYSND1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with TYSND1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix. (PubMed id 22002062)1, 2 Okumoto K.... Fujiki Y. (2011)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Novel peroxisomal protease Tysnd1 processes PTS1- and PTS2-containing enzymes involved in beta-oxidation of fatty acids. (PubMed id 17255948)1, 3 Kurochkin I.V....Okazaki Y. (2007)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    5. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    6. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. Sequence-based discovery of the human and rodent perox isomal proteome. (PubMed id 16128611)1 Kurochkin I.V....Schonbach C. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 219743 HGNC: 28531 AceView: TYSND1 Ensembl:ENSG00000156521 euGenes: HUgn219743
    ECgene: TYSND1 H-InvDB: TYSND1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TYSND1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TYSND1 gene:
    Search GeneIP for patents involving TYSND1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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