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Aliases for TXNRD3NB Gene

Aliases for TXNRD3NB Gene

  • Thioredoxin Reductase 3 Neighbor 2 3 5
  • Thioredoxin Reductase 3 Intronic Transcript 1 2 3 4
  • Thioredoxin Reductase 3 New Transcript 1 2 3 4
  • Thioredoxin Reductase 2 Intronic Transcript 1 3 4
  • Thioredoxin Reductase 3 Neighbor Gene Protein 3 4
  • TXNRD3 Neighbor Gene Protein 3 4
  • TXNRD3IT1 3 4
  • TXNRD3NT1 3 4
  • TR2IT1 3 4
  • Protein TXNRD3NB 3

External Ids for TXNRD3NB Gene

Previous HGNC Symbols for TXNRD3NB Gene

  • TXNRD3IT1

Previous GeneCards Identifiers for TXNRD3NB Gene

  • GC03M126291

Summaries for TXNRD3NB Gene

GeneCards Summary for TXNRD3NB Gene

TXNRD3NB (Thioredoxin Reductase 3 Neighbor) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TXNRD3NB Gene

Genomics for TXNRD3NB Gene

Regulatory Elements for TXNRD3NB Gene

Enhancers for TXNRD3NB Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G126522 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +81.4 81439 8.6 FOXA2 MLX ARID4B DMAP1 ZNF48 YY1 SLC30A9 GLIS2 ZNF143 PAF1 CHST13 TXNRD3NB TXNRD3 NUP210P1 OR7E29P C3orf22 ZXDC UROC1
GH03G126606 1 Ensembl ENCODE 0.7 +1.3 1251 1.0 JUN BACH1 FOSL1 ZNF316 NFE2 FOS MAFK NFE2L2 BHLHE40 MAFG TXNRD3NB PIR61824
GH03G126620 0.4 ENCODE 0.4 -12.7 -12683 0.7 JUND MAX NUP210P1 TXNRD3 LOC100419878 TXNRD3NB
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TXNRD3NB on UCSC Golden Path with GeneCards custom track

Genomic Location for TXNRD3NB Gene

Chromosome:
3
Start:
126,571,779 bp from pter
End:
126,608,555 bp from pter
Size:
36,777 bases
Orientation:
Minus strand

Genomic View for TXNRD3NB Gene

Genes around TXNRD3NB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TXNRD3NB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TXNRD3NB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TXNRD3NB Gene

Proteins for TXNRD3NB Gene

  • Protein details for TXNRD3NB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6F5E7-TR3N_HUMAN
    Recommended name:
    Protein TXNRD3NB
    Protein Accession:
    Q6F5E7

    Protein attributes for TXNRD3NB Gene

    Size:
    133 amino acids
    Molecular mass:
    14331 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The gene encoding this protein shares overlapping exons with TXNRD3. The initiation codon is found in exon 3 of the TXNRD3IT1 gene.

neXtProt entry for TXNRD3NB Gene

Post-translational modifications for TXNRD3NB Gene

No Post-translational modifications

Other Protein References for TXNRD3NB Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TXNRD3NB Gene

Domains & Families for TXNRD3NB Gene

Protein Domains for TXNRD3NB Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TXNRD3NB Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TXNRD3NB: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TXNRD3NB Gene

Function for TXNRD3NB Gene

Phenotypes for TXNRD3NB Gene

GenomeRNAi human phenotypes for TXNRD3NB:
genes like me logo Genes that share phenotypes with TXNRD3NB: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TXNRD3NB Gene

Localization for TXNRD3NB Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TXNRD3NB gene
Compartment Confidence
extracellular 3
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TXNRD3NB Gene

Pathways & Interactions for TXNRD3NB Gene

SuperPathways for TXNRD3NB Gene

No Data Available

Interacting Proteins for TXNRD3NB Gene

Gene Ontology (GO) - Biological Process for TXNRD3NB Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TXNRD3NB Gene

Drugs & Compounds for TXNRD3NB Gene

No Compound Related Data Available

Transcripts for TXNRD3NB Gene

mRNA/cDNA for TXNRD3NB Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TXNRD3NB Gene

No ASD Table

Relevant External Links for TXNRD3NB Gene

GeneLoc Exon Structure for
TXNRD3NB
ECgene alternative splicing isoforms for
TXNRD3NB

Expression for TXNRD3NB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TXNRD3NB Gene

Protein differential expression in normal tissues from HIPED for TXNRD3NB Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TXNRD3NB Gene



Protein tissue co-expression partners for TXNRD3NB Gene

NURSA nuclear receptor signaling pathways regulating expression of TXNRD3NB Gene:

TXNRD3NB

mRNA Expression by UniProt/SwissProt for TXNRD3NB Gene:

Q6F5E7-TR3N_HUMAN
Tissue specificity: Expressed in pancreas, esophagus, bone marrow and keratinocytes.
genes like me logo Genes that share expression patterns with TXNRD3NB: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TXNRD3NB Gene

Orthologs for TXNRD3NB Gene

Evolution for TXNRD3NB Gene

ENSEMBL:
Gene Tree for TXNRD3NB (if available)
TreeFam:
Gene Tree for TXNRD3NB (if available)

No data available for Orthologs for TXNRD3NB Gene

Paralogs for TXNRD3NB Gene

No data available for Paralogs for TXNRD3NB Gene

Variants for TXNRD3NB Gene

Sequence variations from dbSNP and Humsavar for TXNRD3NB Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000077958 -- 126,593,807(+) ATTTG(A/G)TCTTC intron-variant
rs1000114597 -- 126,579,923(+) TACCA(C/T)AAAAC intron-variant
rs1000128879 -- 126,592,385(+) TTAAA(A/T)TTGTT intron-variant
rs1000152491 -- 126,594,061(+) CTTCC(C/T)TTCCT intron-variant
rs1000167124 -- 126,580,301(+) AACAG(A/T)CTGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TXNRD3NB Gene

Variant ID Type Subtype PubMed ID
dgv4852n100 CNV gain 25217958
nsv829717 CNV loss 17160897

Variation tolerance for TXNRD3NB Gene

Residual Variation Intolerance Score: 44.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.61; 56.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TXNRD3NB Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TXNRD3NB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TXNRD3NB Gene

Disorders for TXNRD3NB Gene

Relevant External Links for TXNRD3NB

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TXNRD3NB

No disorders were found for TXNRD3NB Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TXNRD3NB Gene

Publications for TXNRD3NB Gene

  1. Identification and characterization of novel variants of the thioredoxin reductase 3 new transcript 1 TXNRD3NT1. (PMID: 15674732) Matsuzaka Y. … Inoko H. (Mamm. Genome 2005) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  3. Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine- rich regions. (PMID: 15588584) Matsuzaka Y. … Inoko H. (Gene 2004) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TXNRD3NB Gene

Sources for TXNRD3NB Gene

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