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Aliases for TXNRD3NB Gene

Aliases for TXNRD3NB Gene

  • Thioredoxin Reductase 3 Neighbor 2 3
  • Thioredoxin Reductase 3 Intronic Transcript 1 2 3 4
  • Thioredoxin Reductase 3 New Transcript 1 2 3 4
  • Thioredoxin Reductase 2 Intronic Transcript 1 3 4
  • Thioredoxin Reductase 3 Neighbor Gene Protein 3 4
  • TXNRD3 Neighbor Gene Protein 3 4
  • TXNRD3IT1 3 4
  • TXNRD3NT1 3 4
  • TR2IT1 3 4
  • Protein TXNRD3NB 3

External Ids for TXNRD3NB Gene

Previous HGNC Symbols for TXNRD3NB Gene

  • TXNRD3IT1

Previous GeneCards Identifiers for TXNRD3NB Gene

  • GC03M126291

Summaries for TXNRD3NB Gene

GeneCards Summary for TXNRD3NB Gene

TXNRD3NB (Thioredoxin Reductase 3 Neighbor) is a Protein Coding gene. Among its related pathways are Selenium Metabolism and Selenoproteins and Selenium Pathway.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TXNRD3NB Gene

Genomics for TXNRD3NB Gene

Genomic Location for TXNRD3NB Gene

Start:
126,571,779 bp from pter
End:
126,608,555 bp from pter
Size:
36,777 bases
Orientation:
Minus strand

Genomic View for TXNRD3NB Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TXNRD3NB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TXNRD3NB Gene

No data available for Regulatory Elements for TXNRD3NB Gene

Proteins for TXNRD3NB Gene

  • Protein details for TXNRD3NB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6F5E7-TR3N_HUMAN
    Recommended name:
    Protein TXNRD3NB
    Protein Accession:
    Q6F5E7
    Secondary Accessions:

    Protein attributes for TXNRD3NB Gene

    Size:
    133 amino acids
    Molecular mass:
    14331 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The gene encoding this protein shares overlapping exons with TXNRD3. The initiation codon is found in exon 3 of the TXNRD3IT1 gene

neXtProt entry for TXNRD3NB Gene

Proteomics data for TXNRD3NB Gene at MOPED

Post-translational modifications for TXNRD3NB Gene

No Post-translational modifications

Other Protein References for TXNRD3NB Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TXNRD3NB Gene

Domains for TXNRD3NB Gene

Protein Domains for TXNRD3NB Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TXNRD3NB Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TXNRD3NB: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TXNRD3NB Gene

Function for TXNRD3NB Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TXNRD3NB

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TXNRD3NB Gene

Localization for TXNRD3NB Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TXNRD3NB Gene

Pathways for TXNRD3NB Gene

genes like me logo Genes that share pathways with TXNRD3NB: view

Pathways by source for TXNRD3NB Gene

2 BioSystems pathways for TXNRD3NB Gene

Interacting Proteins for TXNRD3NB Gene

Gene Ontology (GO) - Biological Process for TXNRD3NB Gene

None

Transcripts for TXNRD3NB Gene

mRNA/cDNA for TXNRD3NB Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TXNRD3NB

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TXNRD3NB
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TXNRD3NB Gene

No ASD Table

Relevant External Links for TXNRD3NB Gene

GeneLoc Exon Structure for
TXNRD3NB
ECgene alternative splicing isoforms for
TXNRD3NB

Expression for TXNRD3NB Gene

mRNA expression in normal human tissues for TXNRD3NB Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TXNRD3NB Gene

mRNA Expression by UniProt/SwissProt for TXNRD3NB Gene

Q6F5E7-TR3N_HUMAN
Tissue specificity: Expressed in pancreas, esophagus, bone marrow and keratinocytes.
genes like me logo Genes that share expressions with TXNRD3NB: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for TXNRD3NB Gene

Orthologs for TXNRD3NB Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TXNRD3NB Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TXNRD3NB 36
  • 96 (a)
OneToOne
Species with no ortholog for TXNRD3NB:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TXNRD3NB Gene

ENSEMBL:
Gene Tree for TXNRD3NB (if available)
TreeFam:
Gene Tree for TXNRD3NB (if available)

Paralogs for TXNRD3NB Gene

No data available for Paralogs for TXNRD3NB Gene

Variants for TXNRD3NB Gene

Sequence variations from dbSNP and Humsavar for TXNRD3NB Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs708908 -- 126,602,703(+) aagta(C/T)caaac intron-variant
rs777213 -- 126,582,628(-) CTATC(C/T)TCACT intron-variant
rs777214 -- 126,582,580(+) GCATG(C/G)TCTTT intron-variant
rs777215 -- 126,581,597(-) tttca(A/G)ttttt intron-variant
rs777216 -- 126,580,914(-) CAGTT(G/T)TAGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TXNRD3NB Gene

Variant ID Type Subtype PubMed ID
nsv877432 CNV Loss 21882294
nsv829717 CNV Loss 17160897
dgv5246n71 CNV Loss 21882294

Relevant External Links for TXNRD3NB Gene

HapMap Linkage Disequilibrium report
TXNRD3NB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TXNRD3NB Gene

Disorders for TXNRD3NB Gene

No disorders were found for TXNRD3NB Gene.

No data available for UniProtKB/Swiss-Prot for TXNRD3NB Gene

Publications for TXNRD3NB Gene

  1. Identification and characterization of novel variants of the thioredoxin reductase 3 new transcript 1 TXNRD3NT1. (PMID: 15674732) Matsuzaka Y. … Inoko H. (Mamm. Genome 2005) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine- rich regions. (PMID: 15588584) Matsuzaka Y. … Inoko H. (Gene 2004) 3

Products for TXNRD3NB Gene

Sources for TXNRD3NB Gene

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