TXNRD3NB Gene
protein-coding GIFtS: 22
GCID: GC03M126291
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thioredoxin reductase 3 neighbor(Previous name: thioredoxin reductase 3 intronic transcript 1 )
(Previous symbol: TXNRD3IT1)
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Aliases
for TXNRD3NB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Thioredoxin Reductase 3 Neighbor1 2 | | Thioredoxin Reductase 2 Intronic Transcript 12 3 | | Thioredoxin Reductase 3 Intronic Transcript 11 2 3 | | Thioredoxin Reductase 3 Neighbor Gene Protein2 3 | | TR2IT11 2 3 | | Thioredoxin Reductase 3 New Transcript 12 3 | | TXNRD3IT11 2 3 | | TXNRD3 Neighbor Gene Protein2 3 | | TXNRD3NT11 2 3 | | Protein TXNRD3NB2 |
Export aliases for TXNRD3NB gene to outside databases |
Summaries
for TXNRD3NB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TXNRD3NB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TXNRD3NB
Other transcription factors
Search SABiosciences Chromatin IP Primers for TXNRD3NB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TXNRD3NB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q21.3 Ensembl cytogenetic band: 3q21.3 HGNC cytogenetic band: 3q21.3TXNRD3NB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M126291: view genomic region
(about GC identifiers)
Start:
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126,290,622 bp from pter |
End:
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126,327,398 bp from pter |
Size:
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36,777 bases |
Orientation:
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minus strand |
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Proteins
for TXNRD3NB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TR3N_HUMAN, Q6F5E7 (See
protein sequence)Recommended Name: Protein TXNRD3NB Size: 133 amino acids; 14331 Da
Miscellaneous: The gene encoding this protein shares overlapping exons with TXNRD3. The initiation codon is found inexon 3 of the TXNRD3IT1 geneExplore the universe of human proteins at neXtProt for TXNRD3NB: NX_Q6F5E7
TXNRD3NB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001034872.1
ENSEMBL proteins: ENSP00000384071 ENSP00000373066
Human Recombinant Protein Products:
TXNRD3NB Antibody Products:
Assay Products for TXNRD3NB: |
Protein
Domains /
Families
for TXNRD3NB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6F5E7 |
Function
for TXNRD3NB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TXNRD3NB
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TXNRD3NB
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for TXNRD3NB | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TXNRD3NB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TXNRD3NB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNRD3NB |
|
Pathways & Interactions
for TXNRD3NB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TXNRD3NB
|
Drugs & Compounds
for TXNRD3NB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TXNRD3NB
Search CenterWatch for drugs/clinical trials and news about TXNRD3NB / TR3N
|
Transcripts
for TXNRD3NB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TXNRD3NB gene: NM_001039783.1 2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000404489 ENST00000383572
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TXNRD3NB
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TXNRD3NB
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for TXNRD3NB | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TXNRD3NB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TXNRD3NB |
GeneLoc Exon Structure
|
Expression
for TXNRD3NB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TXNRD3NB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See TXNRD3NB Protein Expression from SPIRE MOPED and PaxDBUniProtKB/Swiss-Prot: TR3N_HUMAN, Q6F5E7Tissue specificity: Expressed in pancreas, esophagus, bone marrow and keratinocytes
SABiosciences Custom PCR Arrays for TXNRD3NB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TXNRD3NB
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TXNRD3NB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TXNRD3NB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TXNRD3NB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNRD3NB |
Orthologs
for TXNRD3NB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
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ENSEMBL Gene Tree for TXNRD3NB (if available)
TreeFam Gene Tree for TXNRD3NB (if available) |
Paralogs
for TXNRD3NB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TXNRD3NB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for TXNRD3NB (126290622 - 126327398 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TXNRD3NB: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TXNRD3NB |
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Disorders
/ Diseases
for TXNRD3NB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TXNRD3NB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TXNRD3NB gene integrated from 9 sources:
(articles sorted by number of sources associating them with TXNRD3NB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of novel variants of the thioredoxin reductase 3 new transcript 1 TXNRD3NT1. (PubMed id 15674732)1, 2, 3 Matsuzaka Y.... Inoko H. (2005)
- Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine- rich regions. (PubMed id 15588584)1 Matsuzaka Y.... Inoko H. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for TXNRD3NB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing TXNRD3NB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TXNRD3NB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TXNRD3NB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TXNRD3NB | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for TXNRD3NB gene:
Search GeneIP for patents involving TXNRD3NB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TXNRD3NB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TXNRD3NB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TXNRD3NB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TXNRD3NB | | | OriGene Protein Over-expression Lysate for TXNRD3NB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TXNRD3NB | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TXNRD3NB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TXNRD3NB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TXNRD3NB | | OriGene Custom Protein Services for TXNRD3NB | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TXNRD3NB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TXNRD3NB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TXNRD3NB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TXNRD3NB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TXNRD3NB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TXNRD3NB |
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 | | | TXNRD3NB Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNRD3NB |
|  |  |  | | | | Search ThermoFisher Antibodies for TXNRD3NB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TXNRD3NB |
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