Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TXNDC9 Gene

protein-coding   GIFtS: 53
GCID: GC02M099921

thioredoxin domain containing 9
 Explore 9 diseases affiliated with
TXNDC9 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TXNDC9    

Aliases
for TXNDC9 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Thioredoxin Domain Containing 91 2     PHLP32 5
APACD1 2 3     ATP Binding Protein Associated With Cell Differentiation2
Protein 1-42 3     Thioredoxin Domain-Containing Protein 92
ATP-Binding Protein Associated With Cell Differentiation2 3     

External Ids:    HGNC: 241101   Entrez Gene: 101902   Ensembl: ENSG000001155147   OMIM: 6125645   UniProtKB: O145303   

Export aliases for TXNDC9 gene to outside databases

Previous GC identifers: GC02M099557 GC02M099394 GC02M099301 GC02M099935 GC02M093700


Summaries
for TXNDC9 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TXNDC9:
The protein encoded by this gene is a member of the thioredoxin family. The exact function of this protein is not known
but it is associated with cell differentiation. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TXND9_HUMAN, O14530
Function: Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein
folding, including that of actin or tubulin

Gene Wiki entry for TXNDC9


Genomic Views
for TXNDC9 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022171.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TXNDC9 gene promoter:
         Elk-1   NF-YA   AREB6   NF-YB   IRF-2   CBF-A   CBF-B   CP1A   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TXNDC9 promoter sequence
   Search SABiosciences Chromatin IP Primers for TXNDC9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TXNDC9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

TXNDC9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TXNDC9 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M099921:  view genomic region     (about GC identifiers)

Start:
 99,935,445 bp from pter      End:
 99,957,165 bp from pter
Size:
 21,721 bases      Orientation:
 minus strand

Proteins
for TXNDC9 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TXND9_HUMAN, O14530 (See protein sequence)
Recommended Name: Thioredoxin domain-containing protein 9  
Size: 226 amino acids; 26534 Da
Subunit: Forms ternary complexes with the chaperonin TCP1 complex, spanning the cylindrical chaperonin cavity and
contacting at least 2 subunits
Secondary accessions: B2R9G8 D3DVI4 Q53HG4 Q53RV8 Q6NSF5 Q9BRU6

Explore the universe of human proteins at neXtProt for TXNDC9: NX_O14530

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O14530

    • TXNDC9 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005774.2  
    ENSEMBL proteins: 
     ENSP00000264255   ENSP00000391046   ENSP00000387275   ENSP00000402827   ENSP00000406388  
     ENSP00000386889  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: TXNDC9
    OriGene Protein Over-expression Lysate: TXNDC9
    OriGene Custom Protein Services for TXNDC9 
    GenScript Custom Purified and Recombinant Proteins Services for TXNDC9
    Novus Biologicals TXNDC9 Protein
    Novus Biologicals TXNDC9 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TXNDC9

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IEA--
    GO:0030496midbody IEA--


    TXNDC9 for ontologies           About GeneDecksing



    TXNDC9 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TXNDC9 
    GenScript Custom Superior Antibodies Services for TXNDC9
    Novus Biologicals TXNDC9 Antibodies
    Abcam antibodies for TXNDC9 
    Uscn Antibodies for TXNDC9
    ThermoFisher Antibodies for TXNDC9

    Assay Products for TXNDC9: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TXNDC9
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TXNDC9

    Protein Domains /
    Families
    for TXNDC9 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TXNDC9 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR013766 Thioredoxin_domain
     IPR012336 Thioredoxin-like_fold

    Graphical View of Domain Structure for InterPro Entry O14530

    ProtoNet protein and cluster: O14530

    1 Blocks protein family: IPB006662 Thioredoxin type domain

    UniProtKB/Swiss-Prot: TXND9_HUMAN, O14530
    Similarity: Contains 1 thioredoxin domain


    Function
    for TXNDC9 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TXND9_HUMAN, O14530
    Function: Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein
    folding, including that of actin or tubulin

    miRNA
    Products:            		 OriGene 3'-UTR Clone: TXNDC9
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TXNDC9
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate TXNDC9 (see all 11):
    hsa-miR-3910 hsa-miR-3163 hsa-miR-520d-5p hsa-miR-548e hsa-miR-373* hsa-miR-548a-3p hsa-miR-124 hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmid: TXNDC9 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TXNDC9 (see all 7)
    OriGene shRNA RFP: TXNDC9
    OriGene siRNA: TXNDC9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TXNDC9

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TXNDC9

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TXNDC9 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TXNDC9
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TXNDC9 (NM_005783)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TXNDC9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TXNDC9 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for TXNDC9
    Search LifeMap BioReagents cell lines for TXNDC9

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNDC9

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16169070


    TXNDC9 for ontologies           About GeneDecksing



    Pathways & Interactions
    for TXNDC9 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TXNDC9

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/15 Interacting proteins for TXNDC9 (O145301, 2, 3 ENSP000002642554) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FEZ1Q996891, 2, 3EBI-707554,EBI-396435 MINT-63059 I2D: score=5 
    CHD3Q128732, 3MINT-63062 I2D: score=5 
    GIT1Q9Y2X72, 3MINT-63061 I2D: score=5 
    IMMTQ168912, 3MINT-63057 I2D: score=5 
    KIAA1377Q9P2H02, 3MINT-63060 I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0045454cell redox homeostasis IEA--


    TXNDC9 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TXNDC9 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TXNDC9
    Search CenterWatch for drugs/clinical trials and news about TXNDC9 / TXND9 

    Transcripts
    for TXNDC9 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TXNDC9 gene: 
    NM_005783.3  

    Unigene Cluster for TXNDC9:

    Thioredoxin domain containing 9
    Hs.536122  [show with all ESTs]
    Unigene Representative Sequence: BC070183
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264255(uc002szz.3) ENST00000422767 ENST00000409434(uc002taa.1)
    ENST00000463385 ENST00000438680(uc010yvp.1) ENST00000434323 ENST00000409705
    ENST00000465183 ENST00000477337

    miRNA
    Products:             		 OriGene 3'-UTR Clone: TXNDC9
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TXNDC9
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate TXNDC9 (see all 11):
    hsa-miR-3910 hsa-miR-3163 hsa-miR-520d-5p hsa-miR-548e hsa-miR-373* hsa-miR-548a-3p hsa-miR-124 hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmid: TXNDC9 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TXNDC9 (see all 7)
    OriGene shRNA RFP: TXNDC9
    OriGene siRNA: TXNDC9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TXNDC9
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TXNDC9 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TXNDC9
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TXNDC9 (NM_005783)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TXNDC9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TXNDC9 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TXNDC9
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TXNDC9
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TXNDC9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TXNDC9

    Additional cDNA sequence: 

    AB006679.1 AB451403.1 AK222616.1 AK301722.1 AK313777.1 BC005968.1 BC022864.1 BC024223.2 
    BC070183.1 CR456935.1 

    16 DOTS entries:

    DT.316243  DT.97862008  DT.91772191  DT.100822256  DT.91966541  DT.95172200  DT.100019039  DT.91772187 
    DT.121273261  DT.91772195  DT.100822258  DT.120952270  DT.91698388  DT.95172197  DT.120952358  DT.91966931 

    24/351 AceView cDNA sequences (see all 351):

    BU676257 BQ015141 AA160253 BC070183 CB152411 BQ441198 BG610729 BU675486 
    BC024223 BM454793 CR615367 AA573751 CA411636 AA947866 AL549337 AW235332 
    CR601039 CB242036 AA159916 BU171568 AA731306 BQ014175 BU186390 AU118298 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TXNDC9 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b ^ 6
    SP1:                                            -     -     -                           
    SP2:                                            -     -     -           -     -         
    SP3:                                                  -     -                           
    SP4:                                            -     -     -                           
    SP5:                                            -     -                                 


    ECgene alternative splicing isoforms for TXNDC9

    Expression
    for TXNDC9 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TXNDC9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTGATGTTGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TXNDC9 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FolliclePrimary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TXNDC9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TXNDC9

    SOURCE GeneReport for Unigene cluster: Hs.536122
        SABiosciences Custom PCR Arrays for TXNDC9
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TXNDC9
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TXNDC9
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TXNDC9
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TXNDC9
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNDC9

    Orthologs
    for TXNDC9 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TXNDC9 gene from 9/30 species (see all 30)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Txndc91 , 5 thioredoxin domain containing 91, 5 85.55(n)1
    89.82(a)1    		   1 (16.37 cM)5
    982581  NM_172054.41  NP_742051.11 
     379838675 
    chicken
    (Gallus gallus)    		 Aves TXNDC91 thioredoxin domain containing 9 80.68(n)
    82.74(a)    		   418702  XM_001232594.2  XP_001232595.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TXNDC96
    		 --
    		 78(a)
    		 1 ↔ 1
    		 GL343456.1(13284-22432)
    African clawed frog
    (Xenopus laevis)    		 Amphibia apacd-prov2 ATP binding protein associated with cell differentiation 79.91(n)    BC045061.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufb15e072 wufb15e07 75.73(n)   336625  BC045369.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG45111 CG4511 56.67(n)
    54.29(a)    		   41305  NM_141769.3  NP_650026.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea tag-1701 Protein TAG-170 52.58(n)
    44.85(a)    		   182257  NM_066009.3  NP_498410.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G255801 thioredoxin family protein 55.56(n)
    48.53(a)    		   822145  NM_113455.3  NP_566772.1 
    rice
    (Oryza sativa)    		 Liliopsida Os08g02507001 hypothetical protein 50.08(n)
    46.8(a)    		   4345081  NM_001067910.1  NP_001061375.1 


    ENSEMBL Gene Tree for TXNDC9 (if available)
    TreeFam Gene Tree for TXNDC9 (if available) 

    Paralogs
    for TXNDC9 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TXNDC9 gene

    TXNDC9 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TXNDC9
    PGOHUM00000245540


    Genomic Variants
    for TXNDC9 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/216 NCBI SNPs in TXNDC9 are shown (see all 216)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs121623671,2
    		C,F,A,H,--99935002(+) AGCTAG/CGGGTG 1 -- ds500117Minor allele frequency- C:0.13NS EA NA WA CSA 794
    rs1829039771,2
    		--99935050(+) GTCTAC/TAAGGG 1 -- ds50010--------
    rs1451720941,2
    		--99935098(+) CATCTC/TCTTGC 1 -- ds50010--------
    rs1389542201,2
    		--99935106(+) TGCATA/GGAACC 1 -- ds50010--------
    rs1880118321,2
    		--99935125(+) ACGTAC/TGAGTA 1 -- ds50010--------
    rs746683241,2
    		C,--99935245(+) AGGAAG/AGAGTG 1 -- ds50012Minor allele frequency- A:0.03NA 122
    rs1501137271,2
    		--99935425(+) AAAGAC/TTGACT 1 -- ds50010--------
    rs1385545491,2
    		--99935434(+) CTTTCC/TTGAAA 1 -- ds50010--------
    rs1896822741,2
    		--99935476(+) CAATTG/TCCACA 1 -- ds50010--------
    rs1834494171,2
    		--99935548(+) TCAAAA/CGTGTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TXNDC9 (99935445 - 99957165 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TXNDC9: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TXNDC9
    DNA2.0 Custom Variant and Variant Library Synthesis for TXNDC9

    Disorders / Diseases
    for TXNDC9 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TXNDC9 for disorders           About GeneDecksing

    OMIM gene information: 612564    OMIM disorders: --

    9 diseases for TXNDC9:    About MalaCards
    akinetic mutism    pellagra    mutism    prion disease
    hepatitis b    migraine    hepatitis    malaria
    neuronitis

    3 diseases from the University of Copenhagen DISEASES database for TXNDC9:
    Akinetic mutism     Prion disease     Pellagra

    Export disorders for TXNDC9 gene to outside databases

    Publications
    for TXNDC9 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TXNDC9 gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with TXNDC9)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates. (PubMed id 16415341)1, 2 Stirling P.C.... Leroux M.R. (2006)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner. (PubMed id 22174782)1 Hayes N.V....Carden M.J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    External Searches for TXNDC9 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TXNDC9 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10190 HGNC: 24110 AceView: TXNDC9 Ensembl:ENSG00000115514 euGenes: HUgn10190
    ECgene: TXNDC9 H-InvDB: TXNDC9

    Other Databases showing TXNDC9 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TXNDC9 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TXNDC9 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TXNDC9 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TXNDC9 gene:
    Search GeneIP for patents involving TXNDC9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for TXNDC9 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for TXNDC9  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TXNDC9   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TXNDC9  
     OriGene Protein Over-expression Lysate for TXNDC9   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for TXNDC9   OriGene 3'-UTR Clone for TXNDC9  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TXNDC9   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TXNDC9  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for TXNDC9   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TXNDC9   OriGene Custom Protein Services for TXNDC9  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TXNDC9
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TXNDC9
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TXNDC9
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TXNDC9
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TXNDC9
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TXNDC9
     GenScript Custom Purified and Recombinant Proteins Services for TXNDC9 GenScript cDNA clones with any tag delivered in your preferred vector for TXNDC9
     GenScript Custom Assay Services for TXNDC9 GenScript Custom Superior Antibodies Services for TXNDC9
     GenScript Custom overexpressing Cell Line Services for TXNDC9 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TXNDC9 promoter
     Search Chromatin IP Primers for TXNDC9
     RT2 qPCR Primer Assay in human, mouse, rat TXNDC9
     Search GNC Networks for TXNDC9
     SABiosciences Custom PCR Arrays for TXNDC9
     Search Tocris compounds for TXNDC9
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TXNDC9 antibodies
     TXNDC9 proteins
     TXNDC9 lysates
     Antibodies for TXNDC9
     See all of Abcam's Antibodies, Kits and Proteins for TXNDC9
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     TXNDC9 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TXNDC9
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNDC9
     SwitchGear 3'UTR luciferase reporter plasmids for TXNDC9
     SwitchGear Promoter luciferase reporter plasmids for TXNDC9
     ThermoFisher Antibodies for TXNDC9
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TXNDC9
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      TXNDC9 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4