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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TXNDC2 Gene

protein-coding   GIFtS: 49
GCID: GC18P009875

Thioredoxin Domain Containing 2 (Spermatozoa)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Thioredoxin Domain Containing 2 (Spermatozoa)1 2     sptrx-12
Sperm-Specific Thioredoxin 11 2     Thioredoxin Domain-Containing 2 (Spermatozoa)2
Spermatid-Specific Thioredoxin-12 3     Thioredoxin Domain-Containing Protein 22
SPTRX2 3     Sptrx-13
SPTRX12 3     

External Ids:    HGNC: 164701   Entrez Gene: 842032   Ensembl: ENSG000001684547   UniProtKB: Q86VQ33   

Export aliases for TXNDC2 gene to outside databases

Previous GC identifer: GC18P010019


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TXNDC2 Gene: 
TXNDC2 (thioredoxin domain containing 2 (spermatozoa)) is a protein-coding gene. Diseases associated with TXNDC2 include primary ciliary dyskinesia, and tuberculosis. GO annotations related to this gene include electron carrier activity and thioredoxin-disulfide reductase activity. An important paralog of this gene is TXNDC8.

UniProtKB/Swiss-Prot: TXND2_HUMAN, Q86VQ3
Function: Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath
(FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be
required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can
reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase

Gene Wiki entry for TXNDC2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_010859.14  NC_018929.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TXNDC2 gene promoter:
         CBF-A   CBF-B   NF-YC   CP1A   CBF(2)   CBF-C   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTXNDC2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TXNDC2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TXNDC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  18p11.22   HGNC cytogenetic band: 18p11.31-p11.2

TXNDC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TXNDC2 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P009875:  view genomic region     (about GC identifiers)

Start:
9,885,723 bp from pter      End:
9,889,272 bp from pter
Size:
3,550 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TXND2_HUMAN, Q86VQ3 (See protein sequence)
Recommended Name: Thioredoxin domain-containing protein 2  
Size: 553 amino acids; 60404 Da
Subcellular location: Cytoplasm. Note=In ejaculated spermatozoa, it localizes in the caudal region of the head to
the end of the principal piece
Secondary accessions: Q8N7U4 Q96RX3 Q9H0L8
Alternative splicing: 2 isoforms:  Q86VQ3-1   Q86VQ3-2   

Explore the universe of human proteins at neXtProt for TXNDC2: NX_Q86VQ3

Explore proteomics data for TXNDC2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86VQ3

  • TXNDC2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TXNDC2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001091999.1  NP_115619.4  

    ENSEMBL proteins: 
     ENSP00000437393   ENSP00000464677   ENSP00000350419   ENSP00000304908   ENSP00000400846  

    Human Recombinant Protein Products for TXNDC2: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001520outer dense fiber IEA--
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm ISS--
    GO:0031514motile cilium IEA--

    TXNDC2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR013766 Thioredoxin_domain
     IPR001419 Glutenin
     IPR005746 Thioredoxin
     IPR012336 Thioredoxin-like_fold

    Graphical View of Domain Structure for InterPro Entry Q86VQ3

    ProtoNet protein and cluster: Q86VQ3

    1 Blocks protein domain: IPB006662 Thioredoxin type domain

    UniProtKB/Swiss-Prot: TXND2_HUMAN, Q86VQ3
    Similarity: Contains 1 thioredoxin domain


    TXNDC2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TXND2_HUMAN, Q86VQ3
    Function: Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath
    (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be
    required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can
    reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003756protein disulfide isomerase activity IEA--
    GO:0004791thioredoxin-disulfide reductase activity ISS--
    GO:0009055electron carrier activity IEA--
    GO:0015035protein disulfide oxidoreductase activity IEA--
    GO:0045735nutrient reservoir activity IEA--
         
    TXNDC2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TXNDC2:
     Big cells 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Txndc2):
     growth/size  homeostasis/metabolism  immune system 

    TXNDC2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Txndc2tm1Lex for TXNDC2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TXNDC2 
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    GenScript: all cDNA clones in your preferred vector (see all 2): TXNDC2 (NM_032243)
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                         Customized lentivirus expression plasmids for stable overexpression of TXNDC2 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNDC2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TXNDC2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TXNDC2 (Q86VQ33 ENSP000003049084) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APOA1P026473, ENSP000002368504I2D: score=1 STRING: ENSP00000236850
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding ----
    GO:0006662glycerol ether metabolic process IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis NAS11399755
    GO:0030154cell differentiation IEA--

    TXNDC2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TXNDC2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TXNDC2 (TXND2)

    1 HMDB Compound for TXNDC2    About this table
    CompoundSynonyms CAS #PubMed Ids
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--

    1 Novoseek inferred chemical compound relationship for TXNDC2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nadph 47.1 2 11399755 (1), 12149401 (1)

    Search CenterWatch for drugs/clinical trials and news about TXNDC2 / TXND2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TXNDC2 gene (2 alternative transcripts): 
    NM_001098529.1  NM_032243.5  

    Unigene Cluster for TXNDC2:

    Thioredoxin domain containing 2 (spermatozoa)
    Hs.98712  [show with all ESTs]
    Unigene Representative Sequence: NM_001098529
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000536353 ENST00000584255 ENST00000357775(uc002koh.4) ENST00000306084(uc002koi.4)
    ENST00000426718 ENST00000577697(uc021ugx.1)
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TXNDC2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TXNDC2

    Additional mRNA sequence: 

    AF080095.1 AK097656.1 AK303045.1 BC050132.1 EF560747.1 

    3 DOTS entries:

    DT.75107258  DT.100017816  DT.121083918 

    21 AceView cDNA sequences:

    BM554364 AF080095 BI829219 NM_032243 BI826592 BI831969 BC050132 BM553904 
    BI828938 BM559733 CD557557 AI125222 BI463874 AL136742 AK097656 BI828141 
    BI832369 BI831948 BI831646 BI562175 BI460141 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TXNDC2    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c
    SP1:              -                 -     -                     
    SP2:                                -     -                     
    SP3:                                      -                     
    SP4:                                                            


    ECgene alternative splicing isoforms for TXNDC2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TXNDC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTCTGAAA
    TXNDC2 Expression
    About this image


    See TXNDC2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TXNDC2

    SOURCE GeneReport for Unigene cluster: Hs.98712

    UniProtKB/Swiss-Prot: TXND2_HUMAN, Q86VQ3
    Tissue specificity: Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating
    spermatids

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TXNDC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TXNDC2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Txndc21 , 5 thioredoxin domain containing 2 (spermatozoa)1, 5 68.17(n)1
    47.47(a)1
      17 (34.99 cM)5
    2132721  NM_001146002.11  NP_001139474.11 
     656375055 
    chicken
    (Gallus gallus)
    Aves TXN6
    Thioredoxin
    57(a)
    1 → many
    Z(66343849-66349205)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Thioredoxin
    52(a)
    1 → many
    GL343476.1(264630-273279)
    zebrafish
    (Danio rerio)
    Actinopterygii txn6
    zgc:564936
    zgc:56493
    50(a)
    44(a)
    many ↔ many
    many ↔ many
    7(25524322-25531917)
    1(40656189-40663079)
    worm
    (Caenorhabditis elegans)
    Secernentea trx-16
    Thioredoxin-1
    27(a)
    possible ortholog
    II(7752632-7753607)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRX26
    TRX16
    (see all 3)
    Cytoplasmic thioredoxin isoenzyme of the thioredox...
    Cytoplasmic thioredoxin isoenzyme of the thioredox...
    (see all 3)
    32(a)
    28(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    VII(912913-913227)
    XII(231702-232013)


    ENSEMBL Gene Tree for TXNDC2 (if available)
    TreeFam Gene Tree for TXNDC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TXNDC2 gene
    TXNDC82  TXN2  TXNL12  
    1 SIMAP similar gene for TXNDC2 using alignment to 5 protein entries:     TXND2_HUMAN (see all proteins):
    TXN

    TXNDC2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/219 SNPs in TXNDC2 are shown (see all 219)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1880822371,2
    --9883729(+) TCTTGA/CTCTGT 2 -- us2k10--------
    rs1909391611,2
    --9883773(+) CTCACG/TGCAAC 2 -- us2k10--------
    rs1389167411,2
    --9883816(+) CTCAGA/CCTCCT 2 -- us2k10--------
    rs99464201,2
    C--9883864(+) GCTAAC/GTTTCG 2 -- us2k13Minor allele frequency- G:0.14WA EA 240
    rs1827663481,2
    --9883884(+) TAGAGA/TTCTAA 2 -- us2k10--------
    rs1888856031,2
    --9883894(+) AAATCA/GCATTT 2 -- us2k10--------
    rs1424470421,2
    --9883933(+) CTGTGC/TTGGCA 2 -- us2k10--------
    rs1925905281,2
    --9883987(+) TTGCCC/TCCACA 2 -- us2k10--------
    rs1845650761,2
    --9884162(+) TTGTGC/TTAATA 2 -- us2k10--------
    rs1398031131,2
    --9884170(+) ATAAAA/GTCTGC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TXNDC2 (9885723 - 9889272 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TXNDC2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2716778CNV Deletion23290073
    esv2716777CNV Deletion23290073
    nsv833586CNV Loss17160897
    nsv527829CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TXNDC2:    About MalaCards
    primary ciliary dyskinesia    tuberculosis

    1 disease from the University of Copenhagen DISEASES database for TXNDC2:
    Primary ciliary dyskinesia

    TXNDC2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TXNDC2

    Export disorders for TXNDC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TXNDC2 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with TXNDC2)
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    world of online information

    1. Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa. (PubMed id 11399755)1, 2, 3, 9 Miranda-Vizuete A.... Spyrou G. (2001)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    3. Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity. (PubMed id 12387870)1, 2, 9 Jimenez A.... Miranda-Vizuete A. (2002)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Genome-wide joint meta-analysis of SNP and SNP-by-smok ing interaction identifies novel loci for pulmonary function. (PubMed id 23284291)1 Hancock D.B....London S.J. (2012)
    7. Is serum thioredoxin-1 a useful clinical marker for m alignant pleural mesothelioma? (PubMed id 21375472)1 Maeda R....Nakano T. (2011)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (2007)
    10. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)4 Hwang S.J....Fox C.S. (2007)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84203 HGNC: 16470 AceView: TXNDC2 Ensembl:ENSG00000168454 euGenes: HUgn84203
    ECgene: TXNDC2 H-InvDB: TXNDC2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TXNDC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TXNDC2 gene:
    Search GeneIP for patents involving TXNDC2

    GeneCards and IP:
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