Aliases for TXN2 Gene
External Ids for TXN2 Gene
Previous GeneCards Identifiers for TXN2 Gene
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]
GeneCards Summary for TXN2 Gene
TXN2 (Thioredoxin 2) is a Protein Coding gene. Diseases associated with TXN2 include Combined Oxidative Phosphorylation Deficiency 29 and Ocular Hypertension. Among its related pathways are Cellular Senescence (REACTOME) and Fluid shear stress and atherosclerosis. GO annotations related to this gene include protein complex binding and oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor.
UniProtKB/Swiss-Prot for TXN2 Gene
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.