Aliases for TXN2 Gene
External Ids for TXN2 Gene
Previous GeneCards Identifiers for TXN2 Gene
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]
GeneCards Summary for TXN2 Gene
TXN2 (Thioredoxin 2) is a Protein Coding gene. Diseases associated with TXN2 include Penile Cancer and Ocular Hypertension. Among its related pathways are Glucose / Energy Metabolism and Oxidative Stress. GO annotations related to this gene include protein complex binding and oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor.
UniProtKB/Swiss-Prot for TXN2 Gene
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.