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Aliases for TVP23B Gene

Aliases for TVP23B Gene

  • Trans-Golgi Network Vesicle Protein 23 Homolog B (S. Cerevisiae) 2 3
  • Family With Sequence Similarity 18, Member B1 2 3
  • Family With Sequence Similarity 18, Member B 2 3
  • FAM18B1 3 4
  • FAM18B 3 4
  • Golgi Apparatus Membrane Protein TVP23 Homolog B 3
  • Protein FAM18B1 3
  • CGI-148 3
  • YDR084C 3
  • NPD008 3

External Ids for TVP23B Gene

Previous HGNC Symbols for TVP23B Gene

  • FAM18B
  • FAM18B1

Previous GeneCards Identifiers for TVP23B Gene

  • GC17P018690

Summaries for TVP23B Gene

GeneCards Summary for TVP23B Gene

TVP23B (Trans-Golgi Network Vesicle Protein 23 Homolog B (S. Cerevisiae)) is a Protein Coding gene. An important paralog of this gene is TVP23C-CDRT4.

Gene Wiki entry for TVP23B Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TVP23B Gene

Genomics for TVP23B Gene

Genomic Location for TVP23B Gene

Start:
18,780,995 bp from pter
End:
18,806,714 bp from pter
Size:
25,720 bases
Orientation:
Plus strand

Genomic View for TVP23B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TVP23B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TVP23B Gene

No data available for Regulatory Elements for TVP23B Gene

Proteins for TVP23B Gene

  • Protein details for TVP23B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NYZ1-TV23B_HUMAN
    Recommended name:
    Golgi apparatus membrane protein TVP23 homolog B
    Protein Accession:
    Q9NYZ1
    Secondary Accessions:
    • A8K448
    • Q96HK5
    • Q9Y3E6

    Protein attributes for TVP23B Gene

    Size:
    205 amino acids
    Molecular mass:
    23576 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD34143.1; Type=Frameshift; Positions=178; Evidence={ECO:0000305};

neXtProt entry for TVP23B Gene

Proteomics data for TVP23B Gene at MOPED

Post-translational modifications for TVP23B Gene

  • Ubiquitination at Lys192
  • Modification sites at PhosphoSitePlus

Other Protein References for TVP23B Gene

No data available for DME Specific Peptides for TVP23B Gene

Domains for TVP23B Gene

Protein Domains for TVP23B Gene

Graphical View of Domain Structure for InterPro Entry

Q9NYZ1

UniProtKB/Swiss-Prot:

TV23B_HUMAN :
  • Q9NYZ1
Family:
  • Belongs to the TVP23 family.
genes like me logo Genes that share domains with TVP23B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TVP23B Gene

Function for TVP23B Gene

Animal Model Products

CRISPR Products

miRNA for TVP23B Gene

miRTarBase miRNAs that target TVP23B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TVP23B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TVP23B Gene

Localization for TVP23B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TVP23B Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TVP23B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TVP23B: view

No data available for Subcellular locations from COMPARTMENTS for TVP23B Gene

Pathways for TVP23B Gene

SuperPathways for TVP23B Gene

No Data Available

Interacting Proteins for TVP23B Gene

Gene Ontology (GO) - Biological Process for TVP23B Gene

None

No data available for Pathways by source for TVP23B Gene

Transcripts for TVP23B Gene

Unigene Clusters for TVP23B Gene

Trans-golgi network vesicle protein 23 homolog B (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TVP23B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TVP23B Gene

No ASD Table

Relevant External Links for TVP23B Gene

GeneLoc Exon Structure for
TVP23B
ECgene alternative splicing isoforms for
TVP23B

Expression for TVP23B Gene

mRNA expression in normal human tissues for TVP23B Gene

SOURCE GeneReport for Unigene cluster for TVP23B Gene Hs.87295

genes like me logo Genes that share expressions with TVP23B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TVP23B Gene

Orthologs for TVP23B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TVP23B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TVP23B 35
  • 87.64 (n)
  • 91.22 (a)
TVP23B 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TVP23B 35
  • 89.76 (n)
  • 92.2 (a)
TVP23B 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tvp23b 35
  • 85.04 (n)
  • 92.2 (a)
Tvp23b 16
Tvp23b 36
  • 92 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC455050 35
  • 98.86 (n)
  • 97.56 (a)
TVP23B 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tvp23b 35
  • 84.88 (n)
  • 89.76 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 82 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 80 (a)
OneToMany
chicken
(Gallus gallus)
Aves FAM18B1 35
  • 75.12 (n)
  • 80 (a)
FAM18B1 36
  • 78 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 79 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.7026 35
tvp23b 35
  • 70.77 (n)
  • 77.44 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.18457 35
tvp23b 35
  • 67.53 (n)
  • 73.58 (a)
tvp23b 36
  • 69 (a)
ManyToMany
zgc:112148 36
  • 60 (a)
ManyToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4385 35
fruit fly
(Drosophila melanogaster)
Insecta CG5021 36
  • 40 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea CELE_C34D4.4 35
  • 52.1 (n)
  • 43.71 (a)
C34D4.4 36
  • 29 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TVP23 36
  • 26 (a)
OneToMany
TVP23 38
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4306 36
  • 51 (a)
OneToMany
Species with no ortholog for TVP23B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TVP23B Gene

ENSEMBL:
Gene Tree for TVP23B (if available)
TreeFam:
Gene Tree for TVP23B (if available)

Paralogs for TVP23B Gene

Paralogs for TVP23B Gene

Selected SIMAP similar genes for TVP23B Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for TVP23B Gene

genes like me logo Genes that share paralogs with TVP23B: view

Variants for TVP23B Gene

Sequence variations from dbSNP and Humsavar for TVP23B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1043628 -- 18,805,889(+) ATAGG(C/T)AATGG utr-variant-3-prime
rs1838498 -- 18,805,765(+) AGTAT(A/G)TGTTG utr-variant-3-prime
rs1838499 -- 18,805,787(+) ATTGT(C/T)AAGAT utr-variant-3-prime
rs2270139 -- 18,798,781(+) TCACA(A/G)CATGA intron-variant
rs2386405 -- 18,802,529(-) TAATT(A/G)CCATC intron-variant

Relevant External Links for TVP23B Gene

HapMap Linkage Disequilibrium report
TVP23B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TVP23B Gene

Disorders for TVP23B Gene

No disorders were found for TVP23B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TVP23B Gene

Publications for TVP23B Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for TVP23B Gene

Sources for TVP23B Gene

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