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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TULP4 Gene

protein-coding   GIFtS: 49
GCID: GC06P158733

Tubby Like Protein 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tubby Like Protein 41 2     Tubby Super-Family Protein2
Tubby Superfamily Protein2 3     Tubby-Related Protein 42
Tubby-Like Protein 42 3     KIAA13973
TUSP2 3     TUBL43

External Ids:    HGNC: 155301   Entrez Gene: 569952   Ensembl: ENSG000001303387   UniProtKB: Q9NRJ43   

Export aliases for TULP4 gene to outside databases

Previous GC identifers: GC06P158567 GC06P158642 GC06P158704 GC06P158653 GC06P156205


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TULP4 Gene: 
TULP4 (tubby like protein 4) is a protein-coding gene. Diseases associated with TULP4 include sensenbrenner syndrome, and craniosynostosis. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is TULP2.

UniProtKB/Swiss-Prot: TULP4_HUMAN, Q9NRJ4
Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target
proteins (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_025741.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TULP4 gene promoter:
         ER-alpha   AML1a   MEF-2   MIF-1   Roaz   MEF-2A   POU2F1   POU2F1a   COMP1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TULP4 promoter sequence
   Search SABiosciences Chromatin IP Primers for TULP4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TULP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25-q26   Ensembl cytogenetic band:  6q25.3   HGNC cytogenetic band: 6q25-q26

TULP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TULP4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P158733:  view genomic region     (about GC identifiers)

Start:
158,733,692 bp from pter      End:
158,932,860 bp from pter
Size:
199,169 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TULP4_HUMAN, Q9NRJ4 (See protein sequence)
Recommended Name: Tubby-related protein 4  
Size: 1543 amino acids; 169000 Da
Subcellular location: Cytoplasm
Sequence caution: Sequence=AAF87975.1; Type=Frameshift; Positions=740, 744; Sequence=BAA92635.1; Type=Erroneous
initiation;
Secondary accessions: Q5T3M2 Q5T3M3 Q9HD22 Q9P2F0
Alternative splicing: 2 isoforms:  Q9NRJ4-1   Q9NRJ4-2   

Explore the universe of human proteins at neXtProt for TULP4: NX_Q9NRJ4

Explore proteomics data for TULP4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NRJ4

  • TULP4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TULP4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001007467.1  NP_064630.2  

    ENSEMBL proteins: 
     ENSP00000356061   ENSP00000356064  

    Human Recombinant Protein Products for TULP4: 
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    Novus Biologicals TULP4 Lysates
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TULP4 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA11595174

    TULP4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5/7 InterPro protein domains (see all 7):
     IPR025659 Tubby_C-like
     IPR001680 WD40_repeat
     IPR001496 SOCS_C
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR017986 WD40_repeat_dom

    Graphical View of Domain Structure for InterPro Entry Q9NRJ4

    ProtoNet protein and cluster: Q9NRJ4

    1 Blocks protein domain: IPB001496 SOCS protein

    UniProtKB/Swiss-Prot: TULP4_HUMAN, Q9NRJ4
    Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different
    E3 ubiquitin ligase complexes (By similarity)
    Similarity: Belongs to the TUB family
    Similarity: Contains 1 SOCS box domain
    Similarity: Contains 3 WD repeats


    TULP4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TULP4_HUMAN, Q9NRJ4
    Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
    ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target
    proteins (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity NAS11595174
    GO:0005515protein binding ----
         
    TULP4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TULP4:
     Increased cell death HMECs cel 

    Animal Models:
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    8/79 QIAGEN miScript miRNA Assays for microRNAs that regulate TULP4 (see all 79):
    hsa-miR-549 hsa-miR-607 hsa-miR-199a-3p hsa-miR-30d hsa-miR-502-3p hsa-miR-1273d hsa-miR-30a hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: TULP4_HUMAN, Q9NRJ4
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TULP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for TULP4 (Q9NRJ43 ENSP000003560644) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005193, ENSP000003614234I2D: score=1 STRING: ENSP00000361423
    FYNP062413, ENSP000003576564I2D: score=1 STRING: ENSP00000357656
    PIK3R1P279863, ENSP000002743354I2D: score=1 STRING: ENSP00000274335
    SRCP129313, ENSP000003509414I2D: score=1 STRING: ENSP00000350941
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent NAS11595174
    GO:0007584response to nutrient TAS8612280
    GO:0016567protein ubiquitination IEA--
    GO:0035556intracellular signal transduction IEA--

    TULP4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TULP4

    Search CenterWatch for drugs/clinical trials and news about TULP4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TULP4 gene (2 alternative transcripts): 
    NM_001007466.2  NM_020245.4  

    Unigene Cluster for TULP4:

    Tubby like protein 4
    Hs.486993  [show with all ESTs]
    Unigene Representative Sequence: AF219946
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367094(uc011efo.2) ENST00000367097(uc003qrf.3 uc003qrg.3)

    miRNA
    Products:
         
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    8/79 QIAGEN miScript miRNA Assays for microRNAs that regulate TULP4 (see all 79):
    hsa-miR-549 hsa-miR-607 hsa-miR-199a-3p hsa-miR-30d hsa-miR-502-3p hsa-miR-1273d hsa-miR-30a hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TULP4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TULP4

    Additional mRNA sequence: 

    AB037818.1 AF087973.1 AF219946.2 AF288480.1 AK092091.1 AK304056.1 AK311671.1 BC152476.1 

    7 DOTS entries:

    DT.214505  DT.406280  DT.91861656  DT.121341511  DT.121341516  DT.91646846  DT.121341536 

    24/158 AceView cDNA sequences (see all 158):

    AI479209 BU431073 CK429824 BQ421966 BE465645 BX646714 BI857972 AA931666 
    AI539431 AI539775 CK429667 BX486408 AA547993 BQ071963 AI268331 BG615282 
    AA630774 AA846369 AW769565 N73107 BF915064 BU501516 BG504243 AA063166 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TULP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCAGACCTC
    TULP4 Expression
    About this image


    See TULP4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TULP4

    SOURCE GeneReport for Unigene cluster: Hs.486993

    UniProtKB/Swiss-Prot: TULP4_HUMAN, Q9NRJ4
    Tissue specificity: Expressed mainly in the brain, skeletal muscle, testis and kidney

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TULP4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TULP4 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tulp41 , 5 tubby like protein 41, 5 87.56(n)1
    94.49(a)1
      17 (3.72 cM)5
    688421  NM_054040.31  NP_473381.11 
     61064375 
    chicken
    (Gallus gallus)
    Aves TULP41 tubby like protein 4 77.92(n)
    85.01(a)
      421658  XM_419697.2  XP_419697.2 
    lizard
    (Anolis carolinensis)
    Reptilia TULP46
    Uncharacterized protein
    82(a)
    1 ↔ 1
    1(212838425-212909956)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.182252 Xenopus laevis transcribed sequence with moderate similarity more 79.64(n)    BX852371.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tulp41 tubby like protein 4 69.06(n)
    73.57(a)
      557730  NM_001044838.2  NP_001038303.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tusp6
    Tusp
    35(a)
    1 ↔ 1
    3R(23433986-23460654)
    worm
    (Caenorhabditis elegans)
    Secernentea tub-21 Protein TUB-2 46.95(n)
    39.3(a)
      171758  NM_058512.3  NP_490913.2 


    ENSEMBL Gene Tree for TULP4 (if available)
    TreeFam Gene Tree for TULP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TULP4 gene
    TULP22  TUB2  TULP12  WDR352  TULP32  

    TULP4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4551 SNPs in TULP4 are shown (see all 4551)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs8281451,2
    C,A,H--156285764(+) tatttT/Aaaaaa 2 -- int1 trp31Minor allele frequency- A:0.00NA 2
    rs1456705521,2
    C--158731733(+) TGAGA-/TTTGGA 2 -- us2k10--------
    rs784529291,2
    F--158731757(+) CAAACC/TATGTC 2 -- us2k11Minor allele frequency- T:0.02EA 120
    rs42578801,2
    C,F,A,H--158731839(+) ggactG/Accatg 2 -- us2k1 tfbs315Minor allele frequency- A:0.05NS EA WA NA CSA 776
    rs1918567291,2
    --158731922(+) TACTCA/CAGGGC 2 -- us2k10--------
    rs774639681,2
    C--158731949(+) TAATAA/TTTTTT 2 -- us2k10--------
    rs1824373421,2
    --158732017(+) TAATCG/TATGAC 2 -- us2k10--------
    rs1423523121,2
    --158732050(+) ACCTTA/GATTAG 2 -- us2k10--------
    rs1445824221,2
    --158732147(+) TATTAG/TGATGA 2 -- us2k10--------
    rs1122971721,2
    F--158732168(+) TTTTGG/CTGGGA 2 -- us2k11Minor allele frequency- C:0.50CSA 2

    HapMap Linkage Disequilibrium report for TULP4 (158733692 - 158932860 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/19 variations for TULP4 (see all 19):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2732996CNV Deletion23290073
    dgv1074e201CNV Deletion23290073
    esv4303CNV Deletion18987735
    esv5051CNV Deletion18987735
    esv2235507CNV Deletion18987734
    esv2605411CNV Deletion19546169
    esv2658826CNV Deletion23128226
    esv2116186CNV Deletion18987734
    esv2732994CNV Deletion23290073
    esv2390619CNV Deletion18987734

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for TULP4:    About MalaCards
    sensenbrenner syndrome    craniosynostosis    obesity

    1 disease from the University of Copenhagen DISEASES database for TULP4:
    Sensenbrenner syndrome

    TULP4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TULP4
    Human Genome Epidemiology (HuGE) Navigator: TULP4 (1 document)

    Export disorders for TULP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TULP4 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with TULP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily. (PubMed id 11595174)1, 2, 3, 9 Li Q.-Z.... She J.-X. (2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
    4. Hundreds of variants clustered in genomic loci and bi ological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (2010)
    5. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (2007)
    9. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56995 HGNC: 15530 AceView: TULP4 Ensembl:ENSG00000130338 euGenes: HUgn56995
    ECgene: TULP4 H-InvDB: TULP4

    (According to HUGE)
    About This Section
    HUGE: KIAA1397

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TULP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TULP4 gene:
    Search GeneIP for patents involving TULP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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