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TULP3 Gene

protein-coding   GIFtS: 56
GCID: GC12P002989

Tubby Like Protein 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tubby Like Protein 31 2
Tubby-Like Protein 32 3
TUBL32 3
Tubby-Related Protein 32

External Ids:    HGNC: 124251   Entrez Gene: 72892   Ensembl: ENSG000000782467   OMIM: 6047305   UniProtKB: O753863   

Export aliases for TULP3 gene to outside databases

Previous GC identifers: GC12P002872 GC12P002870 GC12P003000 GC12P002987


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TULP3 Gene:
This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family
have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal
transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region.
The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably
functions as a membrane-bound transcription regulator that translocates to the nucleus in response to
phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important
role in neuronal development and function. Two transcript variants encoding distinct isoforms have been
identified for this gene. (provided by RefSeq, May 2009)

GeneCards Summary for TULP3 Gene:
TULP3 (tubby like protein 3) is a protein-coding gene. GO annotations related to this gene include phosphatidylinositol-4,5-bisphosphate binding and phosphatidylinositol binding. An important paralog of this gene is TULP2.

UniProtKB/Swiss-Prot: TULP3_HUMAN, O75386
Function: Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association
with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a
promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide
(phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G
protein-coupled receptor trafficking. Not involved in ciliogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_009759.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TULP3 gene promoter:
         CREB   E2F   deltaCREB   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTULP3 promoter sequence
   Search Chromatin IP Primers for TULP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TULP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.3   Ensembl cytogenetic band:  12p13.33   HGNC cytogenetic band: 12p13

TULP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TULP3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P002989:  view genomic region     (about GC identifiers)

Start:
2,986,389 bp from pter      End:
3,050,306 bp from pter
Size:
63,918 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TULP3_HUMAN, O75386 (See protein sequence)
Recommended Name: Tubby-related protein 3  
Size: 442 amino acids; 49642 Da
Subunit: Associates with the IFT complex A (IFT-A)
Secondary accessions: B3KNB7 D3DUQ4 Q8N5B0

Explore the universe of human proteins at neXtProt for TULP3: NX_O75386

Explore proteomics data for TULP3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys245, Lys277, Lys316
  • Modification sites at PhosphoSitePlus

  • See TULP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001153880.1  NP_003315.2  

    ENSEMBL proteins: 
     ENSP00000444110   ENSP00000442631   ENSP00000437899   ENSP00000441599   ENSP00000410051  
     ENSP00000380321   ENSP00000441319   ENSP00000440364  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IFT: Intraflagellar transport homologs

    4 InterPro protein domains:
     IPR025659 Tubby_C-like
     IPR018066 Tubby_C_CS
     IPR005398 Tubby_N
     IPR000007 Tubby_C

    Graphical View of Domain Structure for InterPro Entry O75386

    ProtoNet protein and cluster: O75386

    1 Blocks protein domain: IPB000007 Tubby

    UniProtKB/Swiss-Prot: TULP3_HUMAN, O75386
    Similarity: Belongs to the TUB family


    Find genes that share domains with TULP3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TULP3_HUMAN, O75386
    Function: Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association
    with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a
    promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide
    (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G
    protein-coupled receptor trafficking. Not involved in ciliogenesis

         Genatlas biochemistry entry for TULP3:
    tubby-like protein 3,expressed in testis,ovary,thyroid,spinal cord,brain,and in retina,at a moderate level,only in
    the inner nuclear and ganglion cell layers

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0005546phosphatidylinositol-4,5-bisphosphate binding NAS11375483
    GO:0035091phosphatidylinositol binding IDA--
         
    Find genes that share ontologies with TULP3           About GenesLikeMe


    Phenotypes:
         12 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Tulp3):
     cardiovascular system  cellular  craniofacial  embryogenesis  hematopoietic system 
     homeostasis/metabolism  integument  limbs/digits/tail  mortality/aging  nervous system 
     skeleton  vision/eye 

    Find genes that share phenotypes with TULP3           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TULP3

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    miRTarBase miRNAs that target TULP3:
    hsa-mir-93-3p (MIRT038740), hsa-mir-335-5p (MIRT017823)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TULP3_HUMAN, O75386: Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm (By similarity). Secreted (By
    similarity). Note=Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By
    similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding
    protein G(q) subunit alpha
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane5
    cytosol2
    extracellular2

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005634nucleus NAS11375483
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane NAS11375483

    Find genes that share ontologies with TULP3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TULP3
    Interactions:

        Search GeneGlobe Interaction Network for TULP3

    3 Interacting proteins for TULP3 (O753861, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KBTBD7Q8WVZ93I2D: score=1 
    NEBP209291EBI-5357290,EBI-1049657
    vprP125201EBI-5357290,EBI-6164519
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 19):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development ----
    GO:0001843neural tube closure ----
    GO:0006355regulation of transcription, DNA-templated NAS11375483
    GO:0007186G-protein coupled receptor signaling pathway NAS11375483
    GO:0007275multicellular organismal development IEA--

    Find genes that share ontologies with TULP3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Tocris compounds for TULP3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TULP3 gene (2 alternative transcripts): 
    NM_001160408.1  NM_003324.4  

    Unigene Cluster for TULP3:

    Tubby like protein 3
    Hs.655333  [show with all ESTs]
    Unigene Representative Sequence: NM_003324
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000540184 ENST00000544943 ENST00000538354 ENST00000545331 ENST00000448120(uc001qlj.2 uc010seh.1 uc010sei.1)
    ENST00000397132 ENST00000541678 ENST00000538704
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    Additional mRNA sequence: 

    AF045583.1 AK024246.1 AK293285.1 AK307434.1 

    13 DOTS entries:

    DT.111226  DT.100848584  DT.95261985  DT.427274  DT.97842742  DT.121115192  DT.91880485  DT.121115291 
    DT.121115143  DT.91681990  DT.100782300  DT.121115302  DT.102827716 

    Selected AceView cDNA sequences (see all 103):

    BU677224 CD514227 AU130490 AI014684 BX338932 BM682836 AA669058 NM_003324 
    AI652257 AA936526 BM692638 BU733320 AI918733 AI028290 AL556370 CR598112 
    BM663855 BU683007 BQ018476 BM707825 AW069863 AI341445 AI638667 BM465141 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TULP3    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13
    SP1:                                                  -                                                               
    SP2:                                -                 -                                                               
    SP3:                    -     -     -     -     -     -     -     -                                                   
    SP4:                                                                                                                  
    SP5:                                                                                                        -         


    ECgene alternative splicing isoforms for TULP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TULP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGGGAAGGA
    TULP3 Expression
    About this image


    TULP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)
             Testis Somatic Cells Primitive Gonad
     
     Gonad (Reproductive System)
             Testis Somatic Cells Primitive Gonad
    TULP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TULP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655333

    UniProtKB/Swiss-Prot: TULP3_HUMAN, O75386
    Tissue specificity: Expressed at high levels in testis, ovaries, thyroid, and spinal chord

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TULP3 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tulp31 , 5 tubby-like protein 31, 5 74.17(n)1
    72.73(a)1
      6 (62.96 cM)5
    221581  NM_011657.21  NP_035787.11 
     1283211405 
    chicken
    (Gallus gallus)
    Aves TULP31 tubby like protein 3 69.09(n)
    66.59(a)
      426085  XM_423762.4  XP_423762.3 
    lizard
    (Anolis carolinensis)
    Reptilia TULP36
    tubby like protein 3
    60(a)
    1 ↔ 1
    5(80672199-80704456)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tulp31 tubby like protein 3 63.79(n)
    62.7(a)
      100144732  NM_001123481.1  NP_001116953.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5662211 tubby-related protein 3-like 62.77(n)
    62.84(a)
      566221  XM_005164458.1  XP_005164515.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tulp3
    king-tubby1
    king tubby1 50(a)3
    53.61(n)1
    49.01(a)1
      374001  NM_206189.11  NP_995911.11 
    worm
    (Caenorhabditis elegans)
    Secernentea tub-13 Tub family protein tub-1 48(a)   II(8154693-8156859)   --
    corn
    (Zea mays)
    Liliopsida Zm.33782 Zea mays CL768_1 mRNA sequence 72.18(n)    AY109994.1 


    ENSEMBL Gene Tree for TULP3 (if available)
    TreeFam Gene Tree for TULP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TULP3 gene
    TULP22  TULP42  TUB2  TULP12  WDR352  
    3 SIMAP similar genes for TULP3 using alignment to 7 protein entries:     TULP3_HUMAN (see all proteins):
    TULP1    TUB    TULP2

    Find genes that share paralogs with TULP3           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for TULP3
    PGOHUM00000258716


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TULP3 (see all 1357)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs610131941,2
    C--2860641(+) GGGGG-/GGAAATCA 2 -- int11Minor allele frequency- GGA:0.00NA 2
    rs1903843691,2
    --2999341(+) GTTGCA/GGTGAG 2 -- us2k10--------
    rs1828032151,2
    --2999372(+) TGCAGA/TCTGGG 2 -- us2k10--------
    rs1874903721,2
    --2999383(+) CGAGAC/GAGAAA 2 -- us2k10--------
    rs1473715711,2
    --2999392(+) AACCCC/TGTCTC 2 -- us2k10--------
    rs1395758321,2
    --2999527(+) GCCAGC/TCTATG 2 -- us2k10--------
    rs1451920841,2
    --2999590(+) GGTCCA/CCGAAG 2 -- us2k10--------
    rs1932450491,2
    --2999660(+) AGGGCA/TGACCT 2 -- us2k10--------
    rs1471931401,2
    --2999675(+) AAGCGC/TTCTGG 2 -- us2k10--------
    rs3693017871,2
    C--3000063(+) CTCTAC/GCGACG 2 -- ut510--------

    HapMap Linkage Disequilibrium report for TULP3 (2986389 - 3050306 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TULP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2648236CNV Deletion19546169
    nsv579CNV Insertion18451855
    nsv832311CNV Loss17160897
    nsv470261CNV Loss18288195
    dgv19n68CNV Loss17160897

    Human Gene Mutation Database (HGMD): TULP3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TULP3
    DNA2.0 Custom Variant and Variant Library Synthesis for TULP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 604730    OMIM disorders: --


    Find genes that share disorders with TULP3           About GenesLikeMe

    Genetic Association Database (GAD): TULP3
    Human Genome Epidemiology (HuGE) Navigator: TULP3 (2 documents)

    Export disorders for TULP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TULP3 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with TULP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. (PubMed id 9828123)1, 2, 3, 9 Nishina P.M.... Naggert J.K. (Genomics 1998)
    2. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1, 4 Jugessur A....Murray J.C. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. G-protein signaling through tubby proteins. (PubMed id 11375483)1, 2 Santagata S.... Shapiro L. (Science 2001)
    6. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. (PubMed id 23382074)1 Armour S.M....Sinclair D.A. (Mol. Cell. Biol. 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7289 HGNC: 12425 AceView: TULP3 Ensembl:ENSG00000078246 euGenes: HUgn7289
    ECgene: TULP3 H-InvDB: TULP3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TULP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TULP3 gene:
    Search GeneIP for patents involving TULP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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