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Aliases for TUG1 Gene

Subcategory (RNA class) for TUG1 Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for TUG1 Gene

  • Taurine Up-Regulated 1 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 80 2 3
  • Taurine Upregulated 1 (Non-Protein Coding) 2
  • Taurine Upregulated Gene 1 3
  • Non-Protein Coding RNA 80 2
  • TUG1 Noncoding RNA 3
  • NCRNA00080 3
  • LINC00080 3
  • TI-227H 3

External Ids for TUG1 Gene

ORGUL Members for TUG1 Gene

Previous GeneCards Identifiers for TUG1 Gene

  • GC22P029692
  • GC22P031365
  • GC22P014327

Summaries for TUG1 Gene

GeneCards Summary for TUG1 Gene

TUG1 (Taurine Up-Regulated 1 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the lncRNA class.

Gene Wiki entry for TUG1 Gene

fRNAdb sequence ontologies for TUG1 Gene - the ORGUL cluster for this gene includes several descriptions:

  • mature_transcript: A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Taurine upregulated gene 1 conserved region 3: TUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in retina and brain. It was first identified in a screen for genes upregulated by in developing retinal cells in response to taurine. It is required for the normal development of photoreceptors in the retina [1].

  • Taurine upregulated gene 1 conserved region 3: TUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in retina and brain. It was first identified in a screen for genes upregulated by in developing retinal cells in response to taurine. It is required for the normal development of photoreceptors in the retina [1].

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary and piRNA Summary for TUG1 Gene

Genomics for TUG1 Gene

Regulatory Elements for TUG1 Gene

Genomic Location for TUG1 Gene

Start:
30,969,648 bp from pter
End:
30,979,395 bp from pter
Size:
9,748 bases
Orientation:
Plus strand

Genomic View for TUG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TUG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TUG1 Gene

Proteins for TUG1 Gene

Post-translational modifications for TUG1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TUG1 Gene

Domains for TUG1 Gene

Gene Families for TUG1 Gene

HGNC:
  • LNCRNA :Long non-coding RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TUG1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TUG1 Gene

Function for TUG1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TUG1 Gene

Localization for TUG1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TUG1 Gene COMPARTMENTS Subcellular localization image for TUG1 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TUG1 Gene

Pathways for TUG1 Gene

SuperPathways for TUG1 Gene

No Data Available

Interacting Proteins for TUG1 Gene

Gene Ontology (GO) - Biological Process for TUG1 Gene

None

No data available for Pathways by source for TUG1 Gene

Transcripts for TUG1 Gene

Unigene Clusters for TUG1 Gene

Taurine upregulated 1 (non-protein coding):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TUG1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TUG1
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TUG1 Gene

No ASD Table

Relevant External Links for TUG1 Gene

GeneLoc Exon Structure for
TUG1
ECgene alternative splicing isoforms for
TUG1

Expression for TUG1 Gene

mRNA expression in normal human tissues for TUG1 Gene

SOURCE GeneReport for Unigene cluster for TUG1 Gene Hs.554829

genes like me logo Genes that share expressions with TUG1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TUG1 Gene

Orthologs for TUG1 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for TUG1 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Tug1 16
Species with no ortholog for TUG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TUG1 Gene

ENSEMBL:
Gene Tree for TUG1 (if available)
TreeFam:
Gene Tree for TUG1 (if available)

Paralogs for TUG1 Gene

No data available for Paralogs for TUG1 Gene

Variants for TUG1 Gene

Sequence variations from dbSNP and Humsavar for TUG1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs9363 -- 30,977,737(+) GTGAG(A/T)CTAAT nc-transcript-variant
rs12290 -- 30,977,665(+) CCTTT(C/T)TGAAG nc-transcript-variant
rs15211 -- 30,978,506(-) GAAGA(G/T)GTGGT nc-transcript-variant
rs886471 -- 30,970,689(+) TCTAG(G/T)CTGTG nc-transcript-variant
rs1048071 -- 30,973,521(+) GAGTC(A/C)CCTTA nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for TUG1 Gene

Variant ID Type Subtype PubMed ID
nsv9896 CNV Gain 18304495

Relevant External Links for TUG1 Gene

HapMap Linkage Disequilibrium report
TUG1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TUG1 Gene

Disorders for TUG1 Gene

Relevant External Links for TUG1

Genetic Association Database (GAD)
TUG1
genes like me logo Genes that share disorders with TUG1: view

No data available for UniProtKB/Swiss-Prot for TUG1 Gene

Publications for TUG1 Gene

  1. The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. (PMID: 15797018) Young T.L. … Cepko C.L. (Curr. Biol. 2005) 2 3
  2. Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder. (PMID: 22961206) Han Y. … Cai Z. (J Surg Oncol 2013) 2 3
  3. Analysis of long non-coding RNA expression profiles in gastric cancer. (PMID: 23801869) Cao W.J. … Zhang Z.Y. (World J. Gastroenterol. 2013) 2 3
  4. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. (PMID: 24381249) Sauvageau M. … Rinn J.L. (Elife 2013) 2 3
  5. Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. (PMID: 24393600) van Heesch S. … Simonis M. (Genome Biol. 2014) 3

Products for TUG1 Gene

Sources for TUG1 Gene

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