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TUBGCP3 Gene

protein-coding   GIFtS: 57
GCID: GC13M113139

Tubulin, Gamma Complex Associated Protein 3

  Search for TUBGCP3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tubulin, Gamma Complex Associated Protein 31 2     Spc982
Gamma-Ring Complex Protein 104 KDa2 3     Spc98p2
Spindle Pole Body Protein Spc98 Homolog2 3     Gamma-Tubulin Complex Component 32
GCP32 3     GCP-33
Spindle Pole Body Protein1     h104p3
104p2     hGCP33
Grip1042     hGrip1043
SPBC982     hSpc983

External Ids:    HGNC: 185981   Entrez Gene: 104262   Ensembl: ENSG000001262167   UniProtKB: Q96CW53   

Export aliases for TUBGCP3 gene to outside databases

Previous GC identifers: GC13M111749 GC13M107776 GC13M112225 GC13M111087 GC13M112187 GC13M093580


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TUBGCP3 Gene:
TUBGCP3 (tubulin, gamma complex associated protein 3) is a protein-coding gene. GO annotations related to this gene include gamma-tubulin binding and structural molecule activity. An important paralog of this gene is TUBGCP4.

UniProtKB/Swiss-Prot: GCP3_HUMAN, Q96CW5
Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome

Gene Wiki entry for TUBGCP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000013.10  NT_027140.7  NC_018924.2  NT_187592.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the TUBGCP3 gene promoter:
         GR   PPAR-alpha   GR-alpha   YY1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTUBGCP3 promoter sequence
   Search Chromatin IP Primers for TUBGCP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TUBGCP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q34   Ensembl cytogenetic band:  13q34   HGNC cytogenetic band: 13q34

TUBGCP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TUBGCP3 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M113139:  view genomic region     (about GC identifiers)

Start:
113,139,325 bp from pter      End:
113,242,481 bp from pter
Size:
103,157 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: GCP3_HUMAN, Q96CW5 (See protein sequence)
Recommended Name: Gamma-tubulin complex component 3  
Size: 907 amino acids; 103571 Da
Subunit: Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.
Interacts with CDK5RAP2; the interaction is leading to centrosomal localization of TUBGCP3 and CDK5RAP2
Secondary accessions: O43631 O60852 O60853 Q5T8L2 Q7Z4K1 Q96I79
Alternative splicing: 3 isoforms:  Q96CW5-1   Q96CW5-2   Q96CW5-3   

Explore the universe of human proteins at neXtProt for TUBGCP3: NX_Q96CW5

Explore proteomics data for TUBGCP3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys220, Lys276, Lys280, Lys303, Lys379
  • Modification sites at PhosphoSitePlus

  • See TUBGCP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001273206.1  NP_001273207.1  NP_001273208.1  NP_006313.1  

    ENSEMBL proteins: 
     ENSP00000261965   ENSP00000364821  
    Reactome Protein details: Q96CW5

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR015697 GCP3
     IPR007259 TUBGCP

    Graphical View of Domain Structure for InterPro Entry Q96CW5

    ProtoNet protein and cluster: Q96CW5

    1 Blocks protein domain: IPB007259 Spc97/Spc98

    UniProtKB/Swiss-Prot: GCP3_HUMAN, Q96CW5
    Similarity: Belongs to the TUBGCP family


    Find genes that share domains with TUBGCP3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GCP3_HUMAN, Q96CW5
    Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198structural molecule activity NAS9566967
    GO:0005200structural constituent of cytoskeleton NAS9566969
    GO:0005515protein binding IPI17959831
    GO:0043015gamma-tubulin binding IDA9566969
         
    Find genes that share ontologies with TUBGCP3           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for TUBGCP3:
     Decreased viability of wild-ty  Decreased viability with pacli  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 
     Synthetic lethal with c-Myc af 

    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target TUBGCP3:
    hsa-mir-192-5p (MIRT026904), hsa-mir-215-5p (MIRT024502), hsa-let-7b-5p (MIRT052063), hsa-mir-18a-3p (MIRT040911)

    Block miRNA regulation of human, mouse, rat TUBGCP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TUBGCP3 (see all 16):
    hsa-miR-30c hsa-miR-495 hsa-miR-520d-5p hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-30d hsa-miR-410
    SwitchGear 3'UTR luciferase reporter plasmidTUBGCP3 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBGCP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GCP3_HUMAN, Q96CW5: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol4

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000922spindle pole ----
    GO:0005737cytoplasm IDA9566969
    GO:0005813centrosome NAS11694571
    GO:0005814centriole IDA9566969
    GO:0005815microtubule organizing center ----

    Find genes that share ontologies with TUBGCP3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TUBGCP3 About    
    See pathways by source

    SuperPathContained pathways About
    1Regulation of PLK1 Activity at G2/M Transition
    Recruitment of mitotic centrosome proteins and complexes0.86
    Mitotic G2-G2/M phases0.69
    Centrosome maturation0.86
    Recruitment of NuMA to mitotic centrosomes0.00
    G2/M Transition0.70
    2Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    Cell Cycle0.90
    3Nanog in Mammalian ESC Pluripotency
    14-3-3 Induced Intracellular Signaling0.59
    4G-Beta Gamma Signaling
    Hedgehog Signaling in Mammals0.32
    5CDK-mediated phosphorylation and removal of Cdc6
    Parkinson's Disease Pathway0.31


    Find genes that share SuperPaths with TUBGCP3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for TUBGCP3
        14-3-3 Induced Intracellular Signaling
    Hedgehog Signaling in Mammals
    Parkinson's Disease Pathway


    2 Reactome Pathways for TUBGCP3
        Recruitment of mitotic centrosome proteins and complexes
    Recruitment of NuMA to mitotic centrosomes


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TUBGCP3
    Interactions:

        GeneGlobe Interaction Network for TUBGCP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TUBGCP3 (Q96CW52, 3 ENSP000002619654) via UniProtKB, MINT, STRING, and/or I2D (see all 901)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCNTO956132, 3, ENSP000003525724MINT-7947479 I2D: score=3 STRING: ENSP00000352572
    IMMTQ168912, 3, ENSP000003872624MINT-8276031 I2D: score=2 STRING: ENSP00000387262
    TUBG1P232582, 3, ENSP000002514134MINT-7945693 MINT-7947479 I2D: score=5 STRING: ENSP00000251413
    TUBGCP2Q9BSJ22, 3, ENSP000002529364MINT-7945693 MINT-7947479 I2D: score=3 STRING: ENSP00000252936
    DYNC1H1Q142042, ENSP000003489654MINT-7945693 MINT-7947479 STRING: ENSP00000348965
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle TAS--
    GO:0000226microtubule cytoskeleton organization ----
    GO:0000278mitotic cell cycle TAS--
    GO:0007020microtubule nucleation NAS11694571
    GO:0007338single fertilization NAS9138452

    Find genes that share ontologies with TUBGCP3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TUBGCP3 (GCP3)

    1 Novoseek inferred chemical compound relationship for TUBGCP3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sucrose 36.2 1 9566967 (1)



    Find genes that share compounds with TUBGCP3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TUBGCP3 gene (4 alternative transcripts): 
    NM_001286277.1  NM_001286278.1  NM_001286279.1  NM_006322.5  

    Unigene Cluster for TUBGCP3:

    Tubulin, gamma complex associated protein 3
    Hs.224152  [show with all ESTs]
    Unigene Representative Sequence: BC046634
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261965(uc001vse.1 uc010tjq.1) ENST00000469302 ENST00000375669(uc001vsf.3)
    ENST00000462580 ENST00000464139(uc001vsg.1) ENST00000483532
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    hsa-miR-30c hsa-miR-495 hsa-miR-520d-5p hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-30d hsa-miR-410
    SwitchGear 3'UTR luciferase reporter plasmidTUBGCP3 3' UTR sequence
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    Additional mRNA sequence: 

    AF042378.1 AJ003061.1 AJ003062.1 AK302537.1 AK314785.1 BC007763.2 BC013781.1 BC046634.2 
    BT009772.1 L13800.1 L13801.1 

    11 DOTS entries:

    DT.113239  DT.100788660  DT.100788666  DT.40121013  DT.95179955  DT.95214519  DT.100788662  DT.120763339 
    DT.91886396  DT.95179958  DT.95363972 

    Selected AceView cDNA sequences (see all 154):

    AF042378 BC013781 BU623732 BU527799 CK818925 BQ223303 BM474805 AA720688 
    AA233670 CA392672 AI821622 BQ438247 AI268652 BU630764 CD676051 Z45067 
    BT009772 CR616288 BM479981 L13801 BU742889 AL703466 AI190420 L13800 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TUBGCP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAATGAAG
    TUBGCP3 Expression
    About this image


    TUBGCP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    TUBGCP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TUBGCP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.224152

    UniProtKB/Swiss-Prot: GCP3_HUMAN, Q96CW5
    Tissue specificity: Ubiquitously expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBGCP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TUBGCP3 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tubgcp31 , 5 tubulin, gamma complex associated protein 31, 5 85.08(n)1
    92.49(a)1
      8 (5.73 cM)5
    2592791  NM_198031.11  NP_932148.11 
     126142775 
    chicken
    (Gallus gallus)
    Aves TUBGCP31 tubulin, gamma complex associated protein 3 81.24(n)
    91.5(a)
      418750  XM_416949.4  XP_416949.2 
    lizard
    (Anolis carolinensis)
    Reptilia TUBGCP36
    tubulin, gamma complex associated protein 3
    86(a)
    1 ↔ 1
    3(105515703-105584701)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC691342 hypothetical protein MGC69134 78.75(n)    BC057755.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc09h082 Transcribed sequence with moderate similarity to protein more 75.97(n)    BI476157.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(1)dd41 lethal (1) discs degenerate 4 46.57(n)
    37.58(a)
      48481  NM_080180.4  NP_524919.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPC98(YNL126W)4 Component of the microtubule-nucleating Tub4p (gamma-tubulin) more   --   14(387227-389767) 855597  NP_014273.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SPC981 SPC98 48.11(n)
    39.2(a)
      830557  NM_120751.3  NP_196286.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g04462001 Os09g0446200 46.57(n)
    37.43(a)
      4347202  NM_001069843.2  NP_001063308.2 


    ENSEMBL Gene Tree for TUBGCP3 (if available)
    TreeFam Gene Tree for TUBGCP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TUBGCP3 gene
    TUBGCP42  TUBGCP22  

    Find genes that share paralogs with TUBGCP3           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for TUBGCP3
    PGOHUM00000248685


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TUBGCP3 (see all 2249)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs95501161,2
    C,A--94077588(+) CTCTCC/TGAATA 1 -- int14Minor allele frequency- T:0.12NA 8
    rs735645911,2
    C,F--94077643(+) CTCTCG/ATGGAG 1 -- int12Minor allele frequency- A:0.04WA 120
    rs1837539381,2
    --94077655(+) TAAACA/GATATG 1 -- int10--------
    rs1174357841,2
    F--94077718(+) TTTATG/CAACTT 1 -- int11Minor allele frequency- C:0.02EA 120
    rs1883892221,2
    --94077723(+) GAACTG/TCAAAA 1 -- int10--------
    rs802407451,2
    F--94077876(+) GACCTG/AAGCGG 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1419920671,2
    --94077881(+) GAGCGA/GTGACA 1 -- int10--------
    rs118401571,2
    H--94077899(+) TGCTTC/GTATAC 1 -- int10--------
    rs1509016531,2
    --94077901(+) CTTCTA/GTACCA 1 -- int10--------
    rs784137981,2
    C,F--94078051(+) CGAATG/ACATCT 1 -- int11Minor allele frequency- A:0.02NA 120

    HapMap Linkage Disequilibrium report for TUBGCP3 (113139325 - 113242481 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TUBGCP3 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2748159CNV Deletion23290073
    esv2222613CNV Deletion18987734
    esv2433291CNV Deletion19546169
    esv2748160CNV Deletion23290073
    esv2748157CNV Deletion23290073
    esv2748156CNV Deletion23290073
    esv2748158CNV Deletion23290073
    nsv820877CNV Duplication20802225
    esv1008083CNV Loss20482838
    esv23229CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TUBGCP3           About GenesLikeMe

    Genetic Association Database (GAD): TUBGCP3
    Human Genome Epidemiology (HuGE) Navigator: TUBGCP3 (2 documents)

    Export disorders for TUBGCP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TUBGCP3 gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with TUBGCP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin. (PubMed id 9566969)1, 2, 3, 9 Tassin A.-M.... Bornens M. (J. Cell Biol. 1998)
    2. The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p. (PubMed id 9566967)1, 2, 3, 9 Murphy S.M.... Stearns T. (J. Cell Biol. 1998)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex. (PubMed id 17959831)1, 2 Fong K.W.... Qi R.Z. (Mol. Biol. Cell 2008)
    5. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus. (PubMed id 19299467)1, 9 Fant X....Merdes A. (J. Cell. Sci. 2009)
    8. GCP5 and GCP6: two new members of the human gamma-tubulin complex. (PubMed id 11694571)1, 9 Murphy S.M.... Stearns T. (Mol. Biol. Cell 2001)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. Functional replacement of fission yeast I^-tubulin small complex proteins Alp4 and Alp6 by human GCP2 and GCP3. (PubMed id 23886939)1 Riehlman T.D....Paluh J.L. (J. Cell. Sci. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10426 HGNC: 18598 AceView: TUBGCP3 Ensembl:ENSG00000126216 euGenes: HUgn10426
    ECgene: TUBGCP3 H-InvDB: TUBGCP3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TUBGCP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TUBGCP3 gene:
    Search GeneIP for patents involving TUBGCP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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