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TUBGCP2 Gene

protein-coding   GIFtS: 56
GCID: GC10M135094

Tubulin, Gamma Complex Associated Protein 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tubulin, Gamma Complex Associated Protein 21 2     hGrip1032 3
Gamma-Ring Complex Protein 103 KDa2 3     hSpc972 3
Spindle Pole Body Protein Spc97 Homolog2 3     Grip1032
GCP-22 3     SPBC972
GCP22 3     Spc97p2
h103p2 3     Gamma-Tubulin Complex Component 22
hGCP22 3     

External Ids:    HGNC: 185991   Entrez Gene: 108442   Ensembl: ENSG000001306407   UniProtKB: Q9BSJ23   

Export aliases for TUBGCP2 gene to outside databases

Previous GC identifers: GC10M134007 GC10M134223 GC10M135009 GC10M134566 GC10M134982 GC10M134943 GC10M128639


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TUBGCP2 Gene:
TUBGCP2 (tubulin, gamma complex associated protein 2) is a protein-coding gene. Diseases associated with TUBGCP2 include cholera, and parkinson's disease. An important paralog of this gene is TUBGCP4.

UniProtKB/Swiss-Prot: GCP2_HUMAN, Q9BSJ2
Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome

Gene Wiki entry for TUBGCP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TUBGCP2 gene promoter:
         ER-alpha   RFX1   USF1   AP-2alpha isoform 3   AP-2alpha isoform 2   USF-1   STAT3   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTUBGCP2 promoter sequence
   Search Chromatin IP Primers for TUBGCP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TUBGCP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.3   Ensembl cytogenetic band:  10q26.3   HGNC cytogenetic band: 10q26.3

TUBGCP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TUBGCP2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M135094:  view genomic region     (about GC identifiers)

Start:
135,093,135 bp from pter      End:
135,125,841 bp from pter
Size:
32,707 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: GCP2_HUMAN, Q9BSJ2 (See protein sequence)
Recommended Name: Gamma-tubulin complex component 2  
Size: 902 amino acids; 102534 Da
Subunit: Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6
Sequence caution: Sequence=BC005011; Type=Frameshift; Positions=513;
Secondary accessions: B4DM18 B7ZKL8 F5H4E0 F5H4L0 O43632 Q5VWX7
Alternative splicing: 3 isoforms:  Q9BSJ2-1   Q9BSJ2-3   Q9BSJ2-4   (No experimental confirmation available. Ref.4 (AAI43248) sequence is in conflict in position: 209:R->G)

Explore the universe of human proteins at neXtProt for TUBGCP2: NX_Q9BSJ2

Explore proteomics data for TUBGCP2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys157, Lys455
  • Modification sites at PhosphoSitePlus

  • See TUBGCP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001243546.1  NP_001243547.1  NP_006650.1  

    ENSEMBL proteins: 
     ENSP00000252936   ENSP00000357550   ENSP00000436438   ENSP00000473262   ENSP00000357551  
     ENSP00000446093   ENSP00000395666  
    Reactome Protein details: Q9BSJ2

    TUBGCP2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007259 TUBGCP

    Graphical View of Domain Structure for InterPro Entry Q9BSJ2

    ProtoNet protein and cluster: Q9BSJ2

    1 Blocks protein domain: IPB007259 Spc97/Spc98

    UniProtKB/Swiss-Prot: GCP2_HUMAN, Q9BSJ2
    Similarity: Belongs to the TUBGCP family


    TUBGCP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GCP2_HUMAN, Q9BSJ2
    Function: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16980960
         
    TUBGCP2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TUBGCP2:
     Decreased viability with pacli 

    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target TUBGCP2:
    hsa-let-7b-5p (MIRT032408), hsa-mir-24-3p (MIRT030509), hsa-mir-320a (MIRT044719), hsa-mir-92a-3p (MIRT049523), hsa-mir-16-5p (MIRT051231)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GCP2_HUMAN, Q9BSJ2: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol4
    nucleus4
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000922spindle pole IEA--
    GO:0005634nucleus ----
    GO:0005813centrosome IDA--
    GO:0005815microtubule organizing center TAS9566967
    GO:0005829cytosol TAS--

    TUBGCP2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TUBGCP2 About    
    See pathways by source

    SuperPathContained pathways About
    1Regulation of PLK1 Activity at G2/M Transition
    Recruitment of mitotic centrosome proteins and complexes0.86
    Mitotic G2-G2/M phases0.69
    Centrosome maturation0.86
    Recruitment of NuMA to mitotic centrosomes0.00
    G2/M Transition0.70
    2Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    Cell Cycle0.90
    3Nanog in Mammalian ESC Pluripotency
    14-3-3 Induced Intracellular Signaling0.59
    4G-Beta Gamma Signaling
    Hedgehog Signaling in Mammals0.32
    5CDK-mediated phosphorylation and removal of Cdc6
    Parkinson's Disease Pathway0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for TUBGCP2
        14-3-3 Induced Intracellular Signaling
    Hedgehog Signaling in Mammals
    Parkinson's Disease Pathway

    2 Reactome Pathways for TUBGCP2
        Recruitment of mitotic centrosome proteins and complexes
    Recruitment of NuMA to mitotic centrosomes



    TUBGCP2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TUBGCP2
    Interactions:

        GeneGlobe Interaction Network for TUBGCP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TUBGCP2 (Q9BSJ22, 3 ENSP000002529364) via UniProtKB, MINT, STRING, and/or I2D (see all 909)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCNTO956132, 3, ENSP000003525724MINT-7947479 I2D: score=3 STRING: ENSP00000352572
    SRP68Q9UHB92, 3MINT-7945693 MINT-7947479 I2D: score=2 
    TUBG1P232582, 3, ENSP000002514134MINT-7945693 MINT-7947479 MINT-7263751 I2D: score=3 STRING: ENSP00000251413
    TUBGCP3Q96CW52, 3, ENSP000002619654MINT-7945693 MINT-7947479 I2D: score=3 STRING: ENSP00000261965
    DYNC1H1Q142042, ENSP000003489654MINT-7945693 MINT-7947479 STRING: ENSP00000348965
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle TAS--
    GO:0000226microtubule cytoskeleton organization ----
    GO:0000278mitotic cell cycle TAS--
    GO:0006461protein complex assembly TAS9566967
    GO:0007020microtubule nucleation TAS9566967

    TUBGCP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TUBGCP2 (GCP2)

    1 Novoseek inferred chemical compound relationship for TUBGCP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sucrose 29.6 1 9566967 (1)



    TUBGCP2 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TUBGCP2 gene (3 alternative transcripts): 
    NM_001256617.1  NM_001256618.1  NM_006659.3  

    Unigene Cluster for TUBGCP2:

    Tubulin, gamma complex associated protein 2
    Hs.523370  [show with all ESTs]
    Unigene Representative Sequence: NR_046330
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000252936 ENST00000477923 ENST00000368562(uc001lmf.1) ENST00000482278(uc001lmh.1)
    ENST00000487796 ENST00000470829 ENST00000480198 ENST00000368563(uc001lmg.1 uc010qvc.1 uc010qvd.1 uc009ybk.1)
    ENST00000543663 ENST00000417178
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      QuantiFast Probe-based Assays in human, mouse, rat TUBGCP2

    Additional mRNA sequence: 

    AF042379.1 AK092113.1 AK096087.1 AK223586.1 AK297251.1 AK299564.1 AK314520.1 BC005011.1 
    BC093770.1 BC111957.1 BC143247.1 NR_046330.1 

    23 DOTS entries:

    DT.100650692  DT.451655  DT.99943877  DT.100650690  DT.97759918  DT.95255018  DT.70103866  DT.100650694 
    DT.121285626  DT.438974  DT.97759917  DT.100029369  DT.121285513  DT.40126676  DT.91750445  DT.95254999 
    DT.95255003  DT.121285564  DT.121285600  DT.121285620  DT.95255002  DT.121285606  DT.91680333 

    Selected AceView cDNA sequences (see all 296):

    CB130528 BQ945272 CD364860 AU147676 BQ921261 BM893530 BQ285999 BQ217003 
    BP379526 BM979345 BE302810 AA873754 BM558092 BM966742 AI264414 BU552419 
    AW027727 NM_006659 AI033688 AI560879 AI571327 BM973814 BM705507 BI768697 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TUBGCP2 (see all 21)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12a ·
    SP1:                    -     -     -     -                                                           -     -     -     -                       -               
    SP2:                                                                                                                                                            
    SP3:                    -     -     -     -                                                                                                                     
    SP4:                    -     -     -     -     -     -                                                                                                         
    SP5:              -     -     -     -     -                                                                                                                     

    ExUns: 12b · 12c ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b · 18c ^ 19a · 19b ^ 20a · 20b ^ 21a · 21b ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25a · 25b
    SP1:        -           -     -                                                           -           -     -                                   -               
    SP2:                                                                                      -           -     -                                   -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for TUBGCP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TUBGCP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCAGCGTCA
    TUBGCP2 Expression
    About this image

    TUBGCP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TUBGCP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.523370

    UniProtKB/Swiss-Prot: GCP2_HUMAN, Q9BSJ2
    Tissue specificity: Ubiquitously expressed

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TUBGCP2 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tubgcp21 , 5 tubulin, gamma complex associated protein 21, 5 86.4(n)1
    91.24(a)1
      7 (84.98 cM)5
    742371  NM_001286007.11  NP_001272936.11 
     1399959555 
    chicken
    (Gallus gallus)
    Aves TUBGCP21 tubulin, gamma complex associated protein 2 76.29(n)
    85.17(a)
      423673  NM_001006496.1  NP_001006496.1 
    lizard
    (Anolis carolinensis)
    Reptilia TUBGCP26
    tubulin, gamma complex associated protein 2
    75(a)
    1 ↔ 1
    GL344009.1(61964-80941)
    African clawed frog
    (Xenopus laevis)
    Amphibia BM180501.12   -- 78.45(n)    BM180501.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC054908.12   -- 77.9(n)   386975  BC054908.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Grip841 gamma-tubulin ring protein 84 53.15(n)
    38.71(a)
      32946  NM_167663.1  NP_728265.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPC97(YHR172W)4 Component of the microtubule-nucleating Tub4p (gamma-tubulin) more   --   8(448335-450806) 856577  NP_012042.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G174101 AT5G17410 47.39(n)
    41.67(a)
      831607  NM_121747.3  NP_568346.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g05017001 Os04g0501700 46.45(n)
    38.75(a)
      4336312  NM_001059766.1  NP_001053231.1 


    ENSEMBL Gene Tree for TUBGCP2 (if available)
    TreeFam Gene Tree for TUBGCP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TUBGCP2 gene
    TUBGCP42  TUBGCP32  

    TUBGCP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TUBGCP2 (see all 972)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1818574731,2
    C--135092567(+) GGGGAC/TTGGGT 4 -- ut31 nc-transcript-variant0--------
    rs1863674181,2
    --135092573(+) TGGGTC/GTCAGT 4 -- ut31 nc-transcript-variant0--------
    rs30083281,2
    C,F,H--135092590(+) AGTAAC/GTTCTA 4 -- ut31 nc-transcript-variant29Minor allele frequency- G:0.11NS EA NA WA CSA 2780
    rs1413214671,2
    C--135092612(+) GGTACC/TGGATA 4 -- ut31 nc-transcript-variant0--------
    rs1912158151,2
    --135093033(+) GGTGAC/TAGTGT 4 -- ut31 nc-transcript-variant0--------
    rs733926591,2
    C--135093209(+) AATTCT/CGGACC 4 -- ut31 nc-transcript-variant2Minor allele frequency- C:0.05WA 120
    rs2019076091,2
    --135093263(+) CACAGC/GCAGGG 4 -- ut31 nc-transcript-variant0--------
    rs1161226131,2
    C,F--135093287(+) GACTGC/TGACCC 7 T A mis11Minor allele frequency- T:0.03WA 118
    rs2011286701,2
    --135093288(+) ACTGCA/GACCCT 7 V syn10--------
    rs1822521791,2
    --135093294(+) ACCCTA/GGGTGC 7 P syn10--------

    HapMap Linkage Disequilibrium report for TUBGCP2 (135093135 - 135125841 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TUBGCP2 (see all 37):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2894CNV Deletion18987735
    esv2536519CNV Deletion19546169
    dgv2e196CNV Duplication17116639
    dgv3e196CNV Duplication17116639
    esv988628CNV Insertion20482838
    nsv509381CNV Insertion20534489
    nsv512195CNV Loss21212237
    nsv819663CNV Loss19587683
    esv7552CNV Loss19470904
    nsv896312CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TUBGCP2
    DNA2.0 Custom Variant and Variant Library Synthesis for TUBGCP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for TUBGCP2:    
    About MalaCards
    cholera    parkinson's disease    neuroblastoma    malaria


    TUBGCP2 for disorders           About GeneDecksing


    Export disorders for TUBGCP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TUBGCP2 gene, integrated from 10 sources (see all 43):
    (articles sorted by number of sources associating them with TUBGCP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p. (PubMed id 9566967)1, 2, 3, 9 Murphy S.M.... Stearns T. (J. Cell Biol. 1998)
    2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (Genome Biol. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus. (PubMed id 19299467)1, 9 Fant X....Merdes A. (J. Cell. Sci. 2009)
    7. GCP5 and GCP6: two new members of the human gamma-tubulin complex. (PubMed id 11694571)1, 9 Murphy S.M.... Stearns T. (Mol. Biol. Cell 2001)
    8. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1 Cloutier P.... Coulombe B. (PLoS Genet. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10844 HGNC: 18599 AceView: TUBGCP2 Ensembl:ENSG00000130640 euGenes: HUgn10844
    ECgene: TUBGCP2 H-InvDB: TUBGCP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TUBGCP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TUBGCP2 gene:
    Search GeneIP for patents involving TUBGCP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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