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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TUBD1 Gene

protein-coding GIFtS: 50
GCID: GC17M057936

tubulin, delta 1

Explore 5 diseases affiliated with
TUBD1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tubulin, Delta 1¹ ²
TUBD¹ ² ³ ⁵
FLJ12709¹
Delta-Tubulin¹
Tubulin Delta Chain²
Delta-Tubulin¹

External Ids:	HGNC: 16811¹	Entrez Gene: 51174²	Ensembl: ENSG00000108423⁷	OMIM: 607344⁵	UniProtKB: Q9UJT1³

Export aliases for TUBD1 gene to outside databases

Previous GC identifers: GC17M057786 GC17M060386 GC17M058278 GC17M058412 GC17M055291 GC17M053309

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TBD_HUMAN, Q9UJT1

Function: In the elongating spermatid it is associated with the manchette, a specialized microtubule system present

during reshaping of the sperm head (By similarity)

summary for TUBD1:

Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in

turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits

are exposed (-) and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine

cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires

motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end

of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the

spindle fibers for separating chromosomes during mitosis.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010783.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TUBD1 gene promoter:
NF-1/L NF-1 POU3F2 (N-Oct-5a) POU3F2 Evi-1 YY1 CREB E2F E2F-1 deltaCREB
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TUBD1 promoter sequence

Search SABiosciences Chromatin IP Primers for TUBD1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TUBD1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.1 Ensembl cytogenetic band: 17q23.1 HGNC cytogenetic band: 17q23.1

TUBD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TUBD1 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M057936: view genomic region (about GC identifiers)

Start:	57,936,840 bp from pter	End:	57,970,306 bp from pter
Size:	33,467 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TBD_HUMAN, Q9UJT1 (See protein sequence)

Recommended Name: Tubulin delta chain

Size: 453 amino acids; 51034 Da

Subcellular location: Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm. Nucleus. Note=Associated with

centrioles. Both cytoplasmic and nuclear

Secondary accessions: B4DW01 D3DU02 Q9BWG9 Q9H7Z8

Alternative splicing: 4 isoforms: Q9UJT1-1 Q9UJT1-2 Q9UJT1-3 Q9UJT1-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TUBD1: NX_Q9UJT1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UJT1

TUBD1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (6 alternative transcripts):

NP_001180538.1 NP_001180539.1 NP_001180540.1 NP_001180541.1 NP_001180542.1 NP_057345.2

ENSEMBL proteins:

ENSP00000342561 ENSP00000342399 ENSP00000377785 ENSP00000365262 ENSP00000468518

ENSP00000441757 ENSP00000467915 ENSP00000466681 ENSP00000465579 ENSP00000467480

ENSP00000320797

Human Recombinant Protein Products:

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	Novus Biologicals TUBD1 Proteins Novus Biologicals TUBD1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0005794	Golgi apparatus	IDA	--
GO:0005814	centriole	IEA	--

TUBD1 for ontologies About GeneDecksing

TUBD1 Antibody Products:

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Assay Products for TUBD1:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for TUBD1
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TUBD1 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR000217 Tubulin

IPR003008 Tubulin_FtsZ_GTPase

IPR023123 Tubulin_C

IPR008280 Tub_FtsZ_C

IPR002967 Delta_tubulin

Graphical View of Domain Structure for InterPro Entry Q9UJT1

ProtoNet protein and cluster: Q9UJT1

1 Blocks protein family: IPB002967 Delta tubulin signature

UniProtKB/Swiss-Prot: TBD_HUMAN, Q9UJT1

Similarity: Belongs to the tubulin family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TBD_HUMAN, Q9UJT1

Function: In the elongating spermatid it is associated with the manchette, a specialized microtubule system present

during reshaping of the sperm head (By similarity)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TUBD1
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate TUBD1 (see all 10):
		hsa-miR-549 hsa-miR-600 hsa-miR-561 hsa-miR-545 hsa-miR-1179 hsa-miR-570 hsa-miR-514 hsa-miR-4310

		SwitchGear 3'UTR luciferase reporter plasmid: TUBD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TUBD1 (see all 7) OriGene shRNA RFP: TUBD1 OriGene siRNA: TUBD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TUBD1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for TUBD1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TUBD1 (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TUBD1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 6): TUBD1 (NM_001193612)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TUBD1
		Search LifeMap BioReagents cell lines for TUBD1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBD1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003924	GTPase activity	IEA	--
GO:0005198	structural molecule activity	IEA	--
GO:0005525	GTP binding	IEA	--

TUBD1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Sertoli-Sertoli Cell Junction Dynamics

	Sertoli-Sertoli Cell Junction Dynamics	1.00			Epithelial Tight Junctions	0.36
	Germ Cell-Sertoli Cell Junction Dynamics	0.38

Remodeling of Adherens Junctions

Remodeling of Adherens Junctions

1.00

Rho Family GTPases

Molecular Mechanisms of Cancer

0.51

PAK Pathway

Epithelial Adherens Junctions

0.36

G-Beta Gamma Signaling

Hedgehog Signaling in Mammals

0.22

5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TUBD1 (see all 7)

	Sertoli-Sertoli Cell Junction Dynamics
	Remodeling of Adherens Junctions
	Molecular Mechanisms of Cancer
	Epithelial Tight Junctions
	Germ Cell-Sertoli Cell Junction Dynamics

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TUBD1

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

4 Interacting proteins for TUBD1 (Q9UJT1³ ENSP00000320797⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SOCS6	O14544³	I2D: score=1
UBC	ENSP00000344818⁴	STRING: ENSP00000344818
BMPR2	ENSP00000363708⁴	STRING: ENSP00000363708
--	ENSP00000306939⁴	STRING: ENSP00000306939

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007018	microtubule-based movement	IEA	--
GO:0007275	multicellular organismal development	IEA	--
GO:0007283	spermatogenesis	IEA	--
GO:0030154	cell differentiation	IEA	--
GO:0051258	protein polymerization	IEA	--

TUBD1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for TUBD1 available from Tocris Bioscience About this table

Compound	Action	CAS #
XRP44X	Ras-Net pathway inhibitor	[729605-21-4]
Taxol	Promotes assembly and inhibits disassembly of microtubules	[33069-62-4]
Vincristine sulfate	Disrupts microtubules	[2068-78-2]
Vinblastine sulfate	Disrupts microtubules	[143-67-9]
Nocodazole	Microtubule inhibitor	[31430-18-9]

1 DrugBank Compound for TUBD1 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Vinblastine	--	865-21-4	target	adduct	14619954 9664292 1818332 15579115 18220533

Search CenterWatch for drugs/clinical trials and news about TUBD1 / TBD

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TUBD1 gene (6 alternative transcripts):

NM_001193609.1 NM_001193610.1 NM_001193611.1 NM_001193612.1 NM_001193613.1 NM_016261.3

Unigene Cluster for TUBD1:

Tubulin, delta 1

Hs.463638 [show with all ESTs]

Unigene Representative Sequence: NM_016261

15 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000346141(uc010ddi.2) ENST00000340993(uc010ddh.2 uc002ixx.2 uc010ddf.2)

ENST00000394239 ENST00000376094 ENST00000592426 ENST00000539018 ENST00000591548

ENST00000588009 ENST00000593110 ENST00000587476 ENST00000591611 ENST00000590498

ENST00000588706 ENST00000592145 ENST00000325752(uc002ixw.2 uc010wok.2 uc010wol.2 uc010ddg.2)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TUBD1
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate TUBD1 (see all 10):
		hsa-miR-549 hsa-miR-600 hsa-miR-561 hsa-miR-545 hsa-miR-1179 hsa-miR-570 hsa-miR-514 hsa-miR-4310

		SwitchGear 3'UTR luciferase reporter plasmid: TUBD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TUBD1 (see all 7) OriGene shRNA RFP: TUBD1 OriGene siRNA: TUBD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TUBD1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TUBD1 (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TUBD1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TUBD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TUBD1

Additional cDNA sequence:

AB030837.1 AB031044.1 AB031045.1 AF201333.1 AK022771.1 AK024096.1 AK024741.1 AK298492.1

AK301312.1 AK315172.1 BC000258.1

12 DOTS entries:

DT.95362917 DT.100751359 DT.92425648 DT.100024805 DT.100770870 DT.120922374 DT.120922382 DT.100751360

DT.40282483 DT.99981059 DT.100672679 DT.100690674

24/83 AceView cDNA sequences (see all 83):

BX119803 AA370137 BU860436 BU787499 NM_016261 BU782895 BE254093 BU070953

CD358419 BC000258 BQ128350 BP375734 BM972896 BQ549318 AA848060 AL524265

BQ416682 BX459984 BU856950 AI918799 W33134 AF201333 BU782928 AB030837

GeneLoc Exon Structure

5/14 Alternative Splicing Database (ASD) splice patterns (SP) for TUBD1 (see all 14) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7a	·	7b	^	8a	·	8b	^	9	^	10a	·	10b	^	11a	·	11b	·	11c
SP1:																	-		-
SP2:																	-		-												-		-
SP3:																	-		-												-		-		-
SP4:																	-		-
SP5:											-		-						-

ECgene alternative splicing isoforms for TUBD1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TUBD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
See TUBD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TUBD1

SOURCE GeneReport for Unigene cluster: Hs.463638

SABiosciences Custom PCR Arrays for TUBD1

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TUBD1 gene from 6/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	TUBD1¹	tubulin, delta 1	73.88(n) 75.06(a)		417636 XM_415881.3 XP_415881.1
lizard (Anolis carolinensis)	Reptilia	TUBD1⁶	--	71(a)	1 ↔ 1	GL343470.1(217252-220417)
African clawed frog (Xenopus laevis)	Amphibia	tubd1-A-prov²	delta-tubulin	75.72(n)		AF430839.1
zebrafish (Danio rerio)	Actinopterygii	tubd1¹	tubulin, delta 1	62.78(n) 60.76(a)		415183 NM_001002093.1 NP_001002093.1
honey bee (Apis mellifera)	Insecta	--	--	33(a)	1 ↔ 1	GroupUn.621(1663-3000)
worm (Caenorhabditis elegans)	Secernentea	tbg-1⁶	Tubulin gamma chain	19(a)	possible ortholog	III(9625949-9629072)

ENSEMBL Gene Tree for TUBD1 (if available)
TreeFam Gene Tree for TUBD1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TUBD1 gene

TUBG1² TUBG2²

8 SIMAP similar genes for TUBD1 using alignment to 7 protein entries: TBD_HUMAN (see all proteins):

TUBA1 TUBB2B TUBB6 TUBB2A TUBA1A TUBG1

TUBE1 TUBB3

TUBD1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs202071934^1,2	C	--	57936398(+)	`TCATTC/TTTTTT`	6	--	int¹		0	--	--	--	--
rs7223057^1,2	C,F,	--	57936438(+)	`cacccG/Cggctg`	6	--	int¹		7		NA WA EA	366
rs187967796^1,2		--	57936490(+)	`CCCAGA/GCTCAA`	6	--	int¹		0	--	--	--	--
rs111837192^1,2		--	57936491(+)	`CCAGGG/CTCAAG`	6	--	int¹		1		CSA	1
rs181952381^1,2		--	57936497(+)	`TCAAGG/TGATCC`	6	--	int¹		0	--	--	--	--
rs139297143^1,2		--	57936651(+)	`TCCCAC/TTTTGC`	6	--	int¹		0	--	--	--	--
rs141801504^1,2		--	57936828(+)	`AAGTAC/TACATT`	6	--	int¹		0	--	--	--	--
rs147085726^1,2		--	57936863(+)	`CATAAC/GCATTT`	6	--	ut3¹		0	--	--	--	--
rs1298276^1,2	C	--	57936909(-)	`CCACTC/TTAAGC`	6	--	ut3¹ ese³		6		EA NA MN	238
rs148228579^1,2		--	57936965(+)	`AGCATC/TTGACA`	6	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TUBD1 (57936840 - 57970306 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TUBD1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TUBD1

DNA2.0 Custom Variant and Variant Library Synthesis for TUBD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TUBD1 for disorders           About GeneDecksing

OMIM gene information: 607344    OMIM disorders: --

5 diseases for TUBD1:    About MalaCards

prostatic hypertrophy breast cancer neuroblastoma prostatitis

malaria

1 disease from the University of Copenhagen DISEASES database for TUBD1:

Prostatic hypertrophy

Human Genome Epidemiology (HuGE) Navigator: TUBD1 (5 documents)

Export disorders for TUBD1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TUBD1 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with TUBD1)

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Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. (PubMed id 10620804)^{1, 2, 3, 9} Chang P. and Stearns T. (2000)
Delta-tubulin is a component of intercellular bridges and both the early and mature perinuclear rings during spermatogenesis. (PubMed id 15081367)^{1, 2, 9} Kato A.... Todokoro K. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Centrosome-related genes, genetic variation, and risk of breast cancer. (PubMed id 20508983)¹ Olson J.E....Couch F.J. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 51174	HGNC: 16811	AceView: TUBD1	Ensembl:ENSG00000108423	euGenes: HUgn51174
ECgene: TUBD1	H-InvDB: TUBD1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TUBD1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TUBD1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TUBD1 gene:
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tubulin, delta 1

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TUBD1 Gene

tubulin, delta 1

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