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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TUBB7P Gene

pseudogene   GIFtS: 31
GCID: GC04M190906

tubulin, beta 7, pseudogene

(Previous names: tubulin, beta polypeptide 4, member Q, tubulin, beta polypeptide...)
(Previous symbol: TUBB4Q)
  Search for TUBB7P
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Biological research products
for TUBB7P    

Aliases
for TUBB7P gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tubulin, Beta 7, Pseudogene1 2
TUBB4Q1 2
Tubulin, Beta Polypeptide 4, Member Q1
Tubulin, Beta Polypeptide 4, Member Q, Pseudogene1

External Ids:    HGNC: 124131   Entrez Gene: 566042   Ensembl: ENSG000002512977   

Export aliases for TUBB7P gene to outside databases


Summaries
for TUBB7P gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for TUBB7P gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TUBB7P
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TUBB7P

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TUBB7P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q35   Ensembl cytogenetic band:  4q35.2   HGNC cytogenetic band: 4q35.2

TUBB7P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TUBB7P gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M190906:  view genomic region     (about GC identifiers)

Start:
 190,903,678 bp from pter      End:
 190,906,026 bp from pter
Size:
 2,349 bases      Orientation:
 minus strand

Proteins
for TUBB7P gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB: --
Post-translational modifications:
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_

    • TUBB7P Protein expression data from MOPED and PaxDb: --

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    Protein Domains /
    Families
    for TUBB7P gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    		   --

    Function
    for TUBB7P gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
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    Pathways & Interactions
    for TUBB7P gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Pathogenic Escherichia coli infection
    		Pathogenic Escherichia coli infection1.00
    		Pathogenic Escherichia coli infection0.98
    2wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)
    		wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)1.00
    		Regulation of CFTR activity (norm and CF)0.38
    3Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
    		Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway0.93
    		Parkin-Ubiquitin Proteasomal System pathway0.93
    4Cell cycle_Spindle assembly and chromosome separation
    		Cell cycle_Spindle assembly and chromosome separation1.00
    5Cytoskeleton remodeling_Reverse signaling by ephrin B
    		Cytoskeleton remodeling_Reverse signaling by ephrin B1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/10 GeneGo (Thomson Reuters) Pathways for TUBB7P (see all 10)
        Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
    Cell cycle Spindle assembly and chromosome separation
    Regulation of CFTR activity (norm and CF)
    Neurophysiological process Receptor-mediated axon growth repulsion
    Cytoskeleton remodeling Keratin filaments

    2 BioSystems Pathways for TUBB7P 
        Parkin-Ubiquitin Proteasomal System pathway
    Pathogenic Escherichia coli infection


    3         Kegg Pathways  (Kegg details for TUBB7P):
        Phagosome
    Gap junction
    Pathogenic Escherichia coli infection


    TUBB7P for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TUBB7P

    Drugs & Compounds
    for TUBB7P gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for TUBB7P
    Search CenterWatch for drugs/clinical trials and news about TUBB7P 

    Transcripts
    for TUBB7P gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section
    REFSEQ mRNAs for TUBB7P gene: 
    NM_020040.3  

    Unigene Cluster for TUBB7P:

    Tubulin, beta 7, pseudogene
    Hs.351544
    Unigene Representative Sequence: U83110
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000428444(uc011clg.2)

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    Inhib. RNA
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    Additional cDNA sequence: U83110.1 

    2 DOTS entries:

    DT.40120573  DT.91732871 

    3 AceView cDNA sequences:

    AH004935 U83111 NM_020040 

    GeneLoc Exon Structure


    Expression
    for TUBB7P gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TUBB7P expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACGACTTGG
    TUBB7P Expression
    About this image

    TUBB7P expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryAntral FollicleSecondary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    Genevestigator expression for TUBB7P

    SOURCE GeneReport for Unigene cluster: Hs.351544
        SABiosciences Custom PCR Arrays for TUBB7P
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    In Situ
    Assay Products:     
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    Orthologs
    for TUBB7P gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    		   --

    ENSEMBL Gene Tree for TUBB7P (if available)
    TreeFam Gene Tree for TUBB7P (if available) 

    Paralogs
    for TUBB7P gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for TUBB7P gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for TUBB7P gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Publications
    for TUBB7P gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TUBB7P gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TUBB7P)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel beta-tubulin subfamily with one member (TUBB4Q) located near the telomere of chromosome region 4q35. (PubMed id 10828619)1, 3 van Geel M.... Frants R.R. (2000)
    2. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1 Meierhofer D.... Kaiser P. (2008)
    5. Large-scale analysis of the human ubiquitin-related p roteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (2005)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. A cascade of complex subtelomeric duplications during the evolution of the hominoid and Old World monkey genomes. (PubMed id 11731935)1 van Geel M.... de Jong P.J. (2002)
    8. The FSHD region on human chromosome 4q35 contains potential coding regions among pseudogenes and a high density of repeat elements. (PubMed id 10512680)1 van Geel M....de Jong P.J. (1999)

    External Searches for TUBB7P gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TUBB7P gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56604 HGNC: 12413 AceView: TUBB4Q Ensembl:ENSG00000251297 euGenes: HUgn56604
    ECgene: TUBB7P Kegg: 56604 H-InvDB: TUBB7P

    Other Databases showing TUBB7P gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TUBB7P gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TUBB7P Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TUBB7P gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TUBB7P gene:
    Search GeneIP for patents involving TUBB7P

    GeneCards and IP:
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     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TUBB7P
    Sirion Biotech Customized:
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    VWF
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    von Willebrand factor
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