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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TUBA3E Gene

protein-coding GIFtS: 49
GCID: GC02M130949

tubulin, alpha 3e

Explore 2 diseases affiliated with
TUBA3E via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tubulin, Alpha 3e¹ ²
Alpha-Tubulin 3E² ³
Tubulin Alpha-3E Chain²

External Ids:	HGNC: 20765¹	Entrez Gene: 112714²	Ensembl: ENSG00000152086⁷	UniProtKB: Q6PEY2³

Export aliases for TUBA3E gene to outside databases

Previous GC identifers: GC02M130666 GC02M123234

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TBA3E_HUMAN, Q6PEY2

Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on

the beta chain and one at a non-exchangeable site on the alpha chain (By similarity)

summary for TUBA3E:

Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in

turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits

are exposed (-) and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine

cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires

motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end

of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the

spindle fibers for separating chromosomes during mitosis.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022135.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TUBA3E gene promoter:
Sox5 Sp1 NRSF form 1 CUTL1 XBP-1 NRSF form 2 Arnt E47 Roaz RORalpha1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TUBA3E promoter sequence

Search SABiosciences Chromatin IP Primers for TUBA3E

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TUBA3E

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q21.1 Ensembl cytogenetic band: 2q21.1 HGNC cytogenetic band: 2q21.1

TUBA3E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TUBA3E gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M130949: view genomic region (about GC identifiers)

Start:	130,949,318 bp from pter	End:	130,956,034 bp from pter
Size:	6,717 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TBA3E_HUMAN, Q6PEY2 (See protein sequence)

Recommended Name: Tubulin alpha-3E chain

Size: 450 amino acids; 49859 Da

Subunit: Dimer of alpha and beta chains (By similarity)

Subcellular location: Cytoplasm, cytoskeleton (By similarity)

Explore the universe of human proteins at neXtProt for TUBA3E: NX_Q6PEY2

Post-translational modifications:

Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by

the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively (By similarity)¹

Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate

residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated

due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into

axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the

mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation

levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but

they regulate the assembly and dynamics of axonemal microtubules (Probable)¹

Acetylation of alpha chains at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule

motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle

progression or cell differentiation to intracellular trafficking and signaling (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6PEY2

TUBA3E Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_997195.1

ENSEMBL proteins:

ENSP00000318197

Human Recombinant Protein Products for TUBA3E:

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	Browse Proteins at Uscn

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005874	microtubule	IEA	--
GO:0005881	cytoplasmic microtubule	--	--
GO:0015630	microtubule cytoskeleton	IDA	--

TUBA3E for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TUBA3E for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR002452 Alpha_tubulin

IPR000217 Tubulin

IPR003008 Tubulin_FtsZ_GTPase

IPR023123 Tubulin_C

IPR008280 Tub_FtsZ_C

Graphical View of Domain Structure for InterPro Entry Q6PEY2

ProtoNet protein and cluster: Q6PEY2

1 Blocks protein family: IPB002452 Alpha tubulin signature

UniProtKB/Swiss-Prot: TBA3E_HUMAN, Q6PEY2

Similarity: Belongs to the tubulin family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: TBA3E_HUMAN, Q6PEY2

Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on

the beta chain and one at a non-exchangeable site on the alpha chain (By similarity)

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003924	GTPase activity	IEA	--
GO:0005198	structural molecule activity	IEA	--
GO:0005200	structural constituent of cytoskeleton	--	--
GO:0005525	GTP binding	IEA	--
GO:0019904	protein domain specific binding	--	--

TUBA3E for ontologies About GeneDecksing

Phenotypes:
6 GenomeRNAi human phenotypes for TUBA3E:

Cell division defect	Decreased cell number, increas	Decreased viability of wild-ty	Increased cell number in G2M,
Increased gamma-H2AX phosphory	Increased number of mitotic ce

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TUBA3E

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBA3E

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Pathogenic Escherichia coli infection

Pathogenic Escherichia coli infection

1.00

Pathogenic Escherichia coli infection

0.98

wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)

wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)

1.00

Regulation of CFTR activity (norm and CF)

0.38

Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway

Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway

0.93

Parkin-Ubiquitin Proteasomal System pathway

0.93

Cell cycle_Spindle assembly and chromosome separation

Cell cycle_Spindle assembly and chromosome separation

1.00

Cytoskeleton remodeling_Reverse signaling by ephrin B

Cytoskeleton remodeling_Reverse signaling by ephrin B

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

5/10 GeneGo (Thomson Reuters) Pathways for TUBA3E (see all 10)

	Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
	Cell cycle Spindle assembly and chromosome separation
	Regulation of CFTR activity (norm and CF)
	Neurophysiological process Receptor-mediated axon growth repulsion
	Cytoskeleton remodeling Keratin filaments

2 BioSystems Pathways for TUBA3E

	Pathogenic Escherichia coli infection
	Parkin-Ubiquitin Proteasomal System pathway

3 Kegg Pathways (Kegg details for TUBA3E):

	Phagosome
	Gap junction
	Pathogenic Escherichia coli infection

TUBA3E for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TUBA3E

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/583 Interacting proteins for TUBA3E (Q6PEY2^{2, 3} ENSP00000318197⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 583)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PFDN5	Q99471³, ENSP00000334188⁴	I2D: score=2 STRING: ENSP00000334188
PFDN6	O15212³, ENSP00000363734⁴	I2D: score=2 STRING: ENSP00000363734
TIMM50	Q3ZCQ8³, ENSP00000318115⁴	I2D: score=2 STRING: ENSP00000318115
VBP1	P61758³, ENSP00000286428⁴	I2D: score=2 STRING: ENSP00000286428
AIFM1	O95831³, ENSP00000287295⁴	I2D: score=1 STRING: ENSP00000287295

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000226	microtubule cytoskeleton organization	--	--
GO:0007018	microtubule-based movement	IEA	--
GO:0051258	protein polymerization	IEA	--

TUBA3E for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for TUBA3E available from Tocris Bioscience About this table

Compound	Action	CAS #
XRP44X	Ras-Net pathway inhibitor	[729605-21-4]
Taxol	Promotes assembly and inhibits disassembly of microtubules	[33069-62-4]
Vincristine sulfate	Disrupts microtubules	[2068-78-2]
Vinblastine sulfate	Disrupts microtubules	[143-67-9]
Nocodazole	Microtubule inhibitor	[31430-18-9]

1 HMDB Compound for TUBA3E About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

Search CenterWatch for drugs/clinical trials and news about TUBA3E / TBA3E

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TUBA3E gene:

NM_207312.2

Unigene Cluster for TUBA3E:

Tubulin, alpha 3e

Hs.433336 [show with all ESTs]

Unigene Representative Sequence: BC057811

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000312988(uc002tqv.3)

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Additional cDNA sequence:

AK131043.1 BC057811.1

3 DOTS entries:

DT.101980613 DT.99992113 DT.86993860

24/27 AceView cDNA sequences (see all 27):

BG704041 BG721652 AK131043 BI562424 NM_207312 BV196273 BG722213 BI559662

BX282342 BG722455 BG722138 BC057811 BG720572 AI016802 AA977217 AA397983

BX106685 BV204607 BV204609 BV204611 BG717561 T19364 BV204612 T19365

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TUBA3E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

TUBA3E expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Sox17-GFP genetically modified stem cells (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TUBA3E Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.433336

SABiosciences Custom PCR Arrays for TUBA3E

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for TUBA3E gene from 6/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	F1N9J7_CHICK⁶	Uncharacterized protein	98(a)	1 → many	9(25514489-25520697)
lizard (Anolis carolinensis)	Reptilia	TUBA3D⁶	--	98(a)	1 → many	3(28271222-28274672)
zebrafish (Danio rerio)	Actinopterygii	tuba8l4¹	tubulin, alpha 8 like 4	81.7(n) 94.22(a)		393154 NM_200185.1 NP_956479.1
fruit fly (Drosophila melanogaster)	Insecta	alphaTub85E⁶	alpha-Tubulin at 85E	94(a)	possible ortholog	3R(5556943-5558987)
thale cress (Arabidopsis thaliana)	eudicotyledons	TUA6⁶ TUA4⁶ (see all 6)	tubulin alpha-2/alpha-4 chain (see all 6)	82(a) 82(a) (see all 6)	possible ortholog possible ortholog (see all 6)	4(8548492-8550453) 1(1356191-1358386)
rice (Oryza sativa)	Liliopsida	-- -- (see all 4)	tubulin/FtsZ domain containing protein, putative, ... tubulin/FtsZ domain containing protein, putative, ... (see all 4)	82(a) 81(a) (see all 4)	possible ortholog possible ortholog (see all 4)	3(29519151-29522158) 7(23242800-23246249)

ENSEMBL Gene Tree for TUBA3E (if available)
TreeFam Gene Tree for TUBA3E (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TUBA3E gene

TUBA3C² TUBA4A² TUBA1C² TUBA3D² TUBA1B² TUBAL3² TUBA1A² TUBA8²

18/29 SIMAP similar genes for TUBA3E using alignment to 1 protein entry: TBA3E_HUMAN(see all similar genes):

TUBA2 TUBA3C TUBA3D TUBA4A TUBA1 TUBA1A

DKFZp686L04275 TUBA8 TUBA4B TUBA1B TUBA1C TUBAL3

MGC16703 TUBB2A TUBB2B TUBB3 TUBB4Q XTP3TPATP1

TUBA3E for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for TUBA3E
PGOHUM00000235213

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs147121945^1,2		--	130948849(+)	`GTTACC/TGTGGA`	1	--	int¹		0	--	--	--	--
rs1811500^1,2	C,F,A,H	--	130948850(+)	`TTACCG/ATGGAG`	1	--	int¹		9		EA NA WA	452
rs181569170^1,2		--	130948917(+)	`AACTCA/GGTTAA`	1	--	int¹		0	--	--	--	--
rs145725761^1,2		--	130948939(+)	`CCTCT-/AAAATG`	1	--	int¹		0	--	--	--	--
rs184291873^1,2		--	130948977(+)	`CTTTAC/GAGACT`	1	--	int¹		0	--	--	--	--
rs190022637^1,2		--	130949034(+)	`TTTAGC/GCAGCA`	1	--	int¹		0	--	--	--	--
rs115270667^1,2	F	--	130949219(+)	`CCCCAC/TGCCAG`	1	--	int¹		1		WA	118
rs10200523^1,2	C,F	--	130949303(+)	`CTGCAT/CGACAC`	1	--	int¹		7		NA WA EA	366
rs181195557^1,2		--	130949315(+)	`CAGAGA/GTCTTG`	1	--	int¹		0	--	--	--	--
rs143269025^1,2		--	130949351(+)	`AACAAC/GTTGAA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TUBA3E (130949318 - 130956034 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for TUBA3E
7 CNVs: 0269 3393 74253 9430 53632 2408 8387
1 Indel: 33701

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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TUBA3E for disorders About GeneDecksing

2 diseases for TUBA3E: About MalaCards

malaria neuronitis

Export disorders for TUBA3E gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TUBA3E gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with TUBA3E)

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Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Proteomic dissection of the von Hippel-Lindau (VHL) i nteractome. (PubMed id 21942715)¹ Lai Y....Shiio Y. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)¹ Lopitz-Otsoa F....Rodriguez M.S. (2011)
Huwe1, a novel cellular interactor of Gag-Pol through integrase binding, negatively influences HIV-1 infectivity. (PubMed id 21167302)¹ Yamamoto S.P....Suzuki Y. (2011)
Identification of SUMOylated proteins in neuroblastoma cells after treatment with hydrogen peroxide or ascorbate. (PubMed id 21110914)¹ Grant M.M. (2010)
Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)¹ Hutchins J.R....Peters J.M. (2010)
Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. (PubMed id 19524510)² Rogowski K....Janke C. (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 112714	HGNC: 20765	AceView: LOC112714	Ensembl:ENSG00000152086	euGenes: HUgn112714
ECgene: TUBA3E	Kegg: 112714	H-InvDB: TUBA3E

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TUBA3E	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TUBA3E gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TUBA3E gene:
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