Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TUBA1A Gene

protein-coding   GIFtS: 67
GCID: GC12M049578

Tubulin, Alpha 1a

  See TUBA1A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Tubulin, Alpha 1a1 2     tubulin1
TUBA32 3 5     B-ALPHA-12
Tubulin Alpha-3 Chain2 3     hum-a-tub12
Tubulin B-Alpha-12 3     hum-a-tub22
LIS32 5     Tubulin Alpha-1A Chain2
alpha1     Tubulin, Alpha, Brain-Specific2
brain-specific1     Alpha-Tubulin 33

External Ids:    HGNC: 207661   Entrez Gene: 78462   Ensembl: ENSG000001675527   OMIM: 6025295   UniProtKB: Q71U363   

Export aliases for TUBA1A gene to outside databases

Previous GC identifers: GC12M047865 GC12M046609


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for TUBA1A Gene:
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a
heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin
superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families
are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while
gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta
tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to
the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly
found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a
cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition
characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal
migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. (provided by
RefSeq, Jul 2012)

GeneCards Summary for TUBA1A Gene:
TUBA1A (tubulin, alpha 1a) is a protein-coding gene. Diseases associated with TUBA1A include lissencephaly 3, and distal hereditary motor neuropathy, type ii. GO annotations related to this gene include structural molecule activity and GTP binding. An important paralog of this gene is TUBA3C.

UniProtKB/Swiss-Prot: TBA1A_HUMAN, Q71U36
Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site
on the beta chain and one at a non-exchangeable site on the alpha chain

summary for TUBA1A Gene:
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in
turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits
are exposed (-) and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine
cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires
motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end
of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the
spindle fibers for separating chromosomes during mitosis.

Gene Wiki entry for TUBA1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the TUBA1A gene promoter:
         RelA   Roaz   GATA-1   HNF-1A   PPAR-gamma1   CP2   HNF-1   SEF-1 (1)   PPAR-gamma2   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTUBA1A promoter sequence
   Search Chromatin IP Primers for TUBA1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TUBA1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.12

TUBA1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TUBA1A gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M049578:  view genomic region     (about GC identifiers)

Start:
49,578,579 bp from pter      End:
49,583,107 bp from pter
Size:
4,529 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TBA1A_HUMAN, Q71U36 (See protein sequence)
Recommended Name: Tubulin alpha-1A chain  
Size: 451 amino acids; 50136 Da
Subunit: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer
diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form
protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule
plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different
protofilament numbers can be found in some organisms and specialized cells
Secondary accessions: A8K0B8 G3V1U9 P04687 P05209
Alternative splicing: 2 isoforms:  Q71U36-1   Q71U36-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TUBA1A: NX_Q71U36

Explore proteomics data for TUBA1A at MOPED

Post-translational modifications: 

  • Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue
    by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively (By
    similarity)1
  • Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate
    residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not
    polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin
    incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles,
    axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and
    lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such
    modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules (Probable)1
  • Acetylation of alpha chains at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule
    motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle
    progression or cell differentiation to intracellular trafficking and signaling (By similarity)1
  • Ubiquitination2 at Lys60, Lys96, Lys112, Lys163, Lys280, Lys304, Lys311, Lys326, Lys336, Lys338,
                                 Lys352, Lys370, Lys394, Lys401
  • Glycosylation2 at Asn380
  • Modification sites at PhosphoSitePlus

  • See TUBA1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001257328.1  NP_001257329.1  NP_006000.2  

    ENSEMBL proteins: 
     ENSP00000301071   ENSP00000439020   ENSP00000446637   ENSP00000450268   ENSP00000446613  
     ENSP00000448725   ENSP00000449016  
    Reactome Protein details: Q71U36

    TUBA1A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TUBA1A
    OriGene Protein Over-expression Lysate for TUBA1A
    OriGene MassSpec for TUBA1A
    OriGene Custom Protein Services for TUBA1A
    GenScript Custom Purified and Recombinant Proteins Services for TUBA1A
    Novus Biologicals TUBA1A Proteins
    Novus Biologicals TUBA1A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for TUBA1A 

     
    antibodies-online proteins for TUBA1A (12 products) 

     
    antibodies-online peptides for TUBA1A

    TUBA1A Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of TUBA1A
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for TUBA1A 
    OriGene Antibodies for TUBA1A
    OriGene Custom Antibody Services for TUBA1A
    Novus Biologicals TUBA1A Antibodies
    Abcam antibodies for TUBA1A (Q71U36, P68366, Q13748)
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for TUBA1A
    antibodies-online antibodies for TUBA1A (53 products) 

    TUBA1A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TUBA1A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TUBA1A
    Cell Signaling Technology (CST) Sandwich ELISA Kits for TUBA1A
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for TUBA1A 
    antibodies-online kits for TUBA1A (12 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    TUB: Tubulins

    Selected InterPro protein domains (see all 7):
     IPR002452 Alpha_tubulin
     IPR000217 Tubulin
     IPR003008 Tubulin_FtsZ_GTPase
     IPR023123 Tubulin_C
     IPR018316 Tubulin/FtsZ_2-layer-sand-dom

    Graphical View of Domain Structure for InterPro Entry Q71U36

    ProtoNet protein and cluster: Q71U36

    1 Blocks protein domain: IPB002452 Alpha tubulin signature

    UniProtKB/Swiss-Prot: TBA1A_HUMAN, Q71U36
    Similarity: Belongs to the tubulin family


    Find genes that share domains with TUBA1A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TBA1A_HUMAN, Q71U36
    Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site
    on the beta chain and one at a non-exchangeable site on the alpha chain

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity IEA--
    GO:0005198structural molecule activity TAS12090300
    GO:0005200structural constituent of cytoskeleton IEA--
    GO:0005515protein binding IPI19893491
    GO:0005525GTP binding IEA--
         
    Find genes that share ontologies with TUBA1A           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for TUBA1A:
     Decreased cell number, increas  Decreased viability of wild-ty  Increased number of mitotic ce 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Tuba1a):
     behavior/neurological  cellular  growth/size/body  nervous system 

    Find genes that share phenotypes with TUBA1A           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TUBA1A

    miRNA
    Products:
        
    miRTarBase miRNAs that target TUBA1A:
    hsa-mir-124-3p (MIRT022850), hsa-mir-16-5p (MIRT051216), hsa-mir-10a-5p (MIRT047713), hsa-mir-877-3p (MIRT037050), hsa-mir-30a-3p (MIRT001765), hsa-mir-744-5p (MIRT037731), hsa-mir-615-3p (MIRT040369), hsa-mir-324-5p (MIRT043046)

    Block miRNA regulation of human, mouse, rat TUBA1A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TUBA1A (see all 10):
    hsa-miR-15a hsa-miR-3065-3p hsa-miR-497 hsa-miR-339-5p hsa-miR-424 hsa-miR-670 hsa-miR-195 hsa-miR-16
    SwitchGear 3'UTR luciferase reporter plasmidTUBA1A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TUBA1A
    Predesigned siRNA for gene silencing in human, mouse, rat TUBA1A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TUBA1A

    Clone
    Products:
         
    OriGene clones in human, mouse for TUBA1A (see all 6)
    OriGene ORF clones in mouse, rat for TUBA1A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TUBA1A (NM_006009)
    Sino Biological Human cDNA Clone for TUBA1A
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TUBA1A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TUBA1A
    Addgene plasmids for TUBA1A 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TUBA1A
    Browse ESI BIO Cell Lines and PureStem Progenitors for TUBA1A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBA1A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TBA1A_HUMAN, Q71U36: Cytoplasm, cytoskeleton
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol4
    golgi apparatus2
    nucleus2
    plasma membrane2
    endoplasmic reticulum1
    extracellular1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005874microtubule TAS12090300
    GO:0005881cytoplasmic microtubule IEA--
    GO:0015630microtubule cytoskeleton ----
    GO:0043234protein complex ----

    Find genes that share ontologies with TUBA1A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for TUBA1A About   (see all 16)  
    See pathways by source

    SuperPathContained pathways About
    1Development Slit Robo signaling
    Development Slit Robo signaling0.92
    Pathogenic Escherichia coli infection0.41
    Cytoskeleton remodeling Slit Robo signaling0.92
    Neurophysiological process Receptor mediated axon growth repulsion0.41
    Pathogenic Escherichia coli infection0.43
    2Parkin-Ubiquitin Proteasomal System pathway
    Proteolysis Role of Parkin in the Ubiquitin Proteasomal Pathway0.89
    Parkin-Ubiquitin Proteasomal System pathway0.89
    3Cytoplasmic microtubules
    Cytoplasmic microtubules0.32
    Cytoskeleton remodeling Neurofilaments0.32
    4Regulation of PLK1 Activity at G2/M Transition
    Recruitment of mitotic centrosome proteins and complexes0.86
    Regulation of PLK1 Activity at G2/M Transition0.77
    Loss of Nlp from mitotic centrosomes0.86
    G2/M Transition0.70
    Centrosome maturation0.86
    Mitotic G2-G2/M phases0.69
    Loss of proteins required for interphase microtubule organizationfrom the centrosome0.86
    5Protein folding
    Chaperonin-mediated protein folding0.91
    Post-chaperonin tubulin folding pathway0.00
    Protein folding0.91


    Find genes that share SuperPaths with TUBA1A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for TUBA1A
        Cytoskeletal Signaling

    Selected GeneGo (Thomson Reuters) Pathways for TUBA1A (see all 10)
        Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
    Cell cycle Spindle assembly and chromosome separation
    Regulation of CFTR activity (norm and CF)
    Neurophysiological process Receptor-mediated axon growth repulsion
    Cytoskeleton remodeling Keratin filaments

    2 BioSystems Pathways for TUBA1A
        Parkin-Ubiquitin Proteasomal System pathway
    Pathogenic Escherichia coli infection


    Selected Reactome Pathways for TUBA1A (see all 17)
        Resolution of Sister Chromatid Cohesion
    Prefoldin mediated transfer of substrate to CCT/TriC
    Mitotic Prometaphase
    Recruitment of mitotic centrosome proteins and complexes
    Recruitment of NuMA to mitotic centrosomes


    3 Kegg Pathways  (Kegg details for TUBA1A):
        Phagosome
    Gap junction
    Pathogenic Escherichia coli infection

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TUBA1A
    Interactions:

        Search GeneGlobe Interaction Network for TUBA1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TUBA1A (Q71U361, 2, 3 ENSP000003010714) via UniProtKB, MINT, STRING, and/or I2D (see all 269)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000232421P074372, 3, ENSP000004108294MINT-7220149 I2D: score=1 STRING: ENSP00000410829
    CYLDQ9NQC71, 2, 3, ENSP000003089284EBI-302552,EBI-2117940 MINT-7562676 MINT-7561617 MINT-7563186 MINT-7623764 MINT-7679557 MINT-7561703 MINT-7679902 I2D: score=2 STRING: ENSP00000308928
    ENSG00000183311P074372, 3MINT-7220149 I2D: score=1 
    ENSG00000224156P074372, 3MINT-7220149 I2D: score=1 
    ENSG00000227739P074372, 3MINT-7220149 I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle TAS--
    GO:0000226microtubule cytoskeleton organization ----
    GO:0000278mitotic cell cycle TAS--
    GO:0006184GTP catabolic process ----
    GO:0006457protein folding TAS--

    Find genes that share ontologies with TUBA1A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
    9 ApexBio Compounds for TUBA1A     About this table
    CompoundAction CAS #
    7-xylosyltaxoltaxol (Paclitaxel) derivative[90332-66-4]
    ColchicineColchicine, a tubulin Inhibitor[64-86-8]
    D-64131novel inhibitor of Tubulin polymerization[74588-78-6]
    Docetaxel Trihydrateinhibitor of depolymerisation of microtubules[148408-66-6]
    Mc-MMADPotent tubulin inhibitor[1401963-15-2]
    MMADPotent tubulin inhibitor[203849-91-6]
    Monomethyl auristatin EAntimitotic agent[474645-27-7]
    PodophyllotoxinActions Inhibits microtubule assembly[518-28-5]
    Vc-MMADantibody drug conjugate[1401963-17-4]

    Compounds for TUBA1A available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Vinorelbine ditartrateSelective mitotic microtubule antagonist[125317-39-7]
    DocetaxelMicrotubule stabilizer[114977-28-5]
    Vinblastine sulfateDisrupts microtubules[143-67-9]
    ColchicineInhibitor of tubulin[64-86-8]
    Epothilone BMicrotubule stabilization agent; promotes tubulin polymerization[152044-54-7]

    1 HMDB Compound for TUBA1A    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    6 DrugBank Compounds for TUBA1A    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Mebendazole-- 31431-39-7targetinhibitor12099434 11444621 15500920 8139621 17662615 10592235
    Vinblastine-- 865-21-4targetadduct14619954 9664292 1818332 15579115 18220533
    Albendazole-- 54965-21-8targetinhibitor11343808 19846910 10592235
    Epothilone BEPO 906 (see all 3)152044-54-7target--17139284 17016423
    Epothilone D-- 189453-10-9target--17139284 17016423
    2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TUBA1A gene (3 alternative transcripts): 
    NM_001270399.1  NM_001270400.1  NM_006009.3  

    Unigene Cluster for TUBA1A:

    Tubulin, alpha 1a
    Hs.654422  [show with all ESTs]
    Unigene Representative Sequence: NM_001270399
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000301071(uc001rtp.3) ENST00000295766(uc009zlf.3) ENST00000550767
    ENST00000547939 ENST00000546918 ENST00000552924 ENST00000548363 ENST00000550254
    ENST00000550811
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TUBA1A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TUBA1A (see all 10):
    hsa-miR-15a hsa-miR-3065-3p hsa-miR-497 hsa-miR-339-5p hsa-miR-424 hsa-miR-670 hsa-miR-195 hsa-miR-16
    SwitchGear 3'UTR luciferase reporter plasmidTUBA1A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TUBA1A
    Predesigned siRNA for gene silencing in human, mouse, rat TUBA1A
    Clone
    Products:
         
    OriGene clones in human, mouse for TUBA1A (see all 6)
    OriGene ORF clones in mouse, rat for TUBA1A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TUBA1A (NM_006009)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TUBA1A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TUBA1A
    Addgene plasmids for TUBA1A 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TUBA1A
    OriGene qSTAR qPCR primer pairs in human, mouse for TUBA1A
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TUBA1A
      QuantiTect SYBR Green Assays in human, mouse, rat TUBA1A
      QuantiFast Probe-based Assays in human, mouse, rat TUBA1A

    Additional mRNA sequence: 

    AF141347.1 AF141348.1 AK057842.1 AK289483.1 AK297775.1 AK298838.1 BC006468.1 BC050637.2 
    BC057823.1 K00557.1 

    Selected DOTS entries (see all 192):

    DT.91979576  DT.100744535  DT.92475435  DT.95174349  DT.97808025  DT.100744483  DT.99926623  DT.100744508 
    DT.100744455  DT.95174340  DT.100772180  DT.100744390  DT.100803172  DT.100862201  DT.100856626  DT.95174563 
    DT.100744449  DT.100744501  DT.121136681  DT.121135196  DT.100744539  DT.121135985  DT.95174557  DT.95174282 

    Selected AceView cDNA sequences (see all 302):

    CR607886 CR602196 CR597522 CR617729 CR623665 CR624173 CR593877 CR610649 
    CR607938 CR624073 CR621713 CR603752 CR614113 CR592123 CR594062 CR593163 
    CR625134 CR592146 CR604014 CR601913 CR604076 CR602040 CR598989 CR626641 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TUBA1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATGCTTTGT
    TUBA1A Expression
    About this image


    TUBA1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 18) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)
             Oviduct
     
     Cartilage (Muscoskeletal System)
             Intervertebral Disc Nucleus Pulposus Cells Nucleus Pulposus
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Bone (Muscoskeletal System)
             Bone Marrow
    TUBA1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TUBA1A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654422

    UniProtKB/Swiss-Prot: TBA1A_HUMAN, Q71U36
    Tissue specificity: Expressed at a high level in fetal brain

        Custom PCR Arrays for TUBA1A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TUBA1A
    OriGene qSTAR qPCR primer pairs in human, mouse for TUBA1A
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TUBA1A
    QuantiTect SYBR Green Assays in human, mouse, rat TUBA1A
    QuantiFast Probe-based Assays in human, mouse, rat TUBA1A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBA1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TUBA1A gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tuba1a1 , 5 tubulin, alpha 1A1, 5 93.64(n)1
    100(a)1
      15 (55.29 cM)5
    221421  NM_011653.21  NP_035783.11 
     989498415 
    chicken
    (Gallus gallus)
    Aves TUBA3E1 tubulin, alpha 3e 80.66(n)
    95.56(a)
      421169  XM_419249.4  XP_419249.3 
    lizard
    (Anolis carolinensis)
    Reptilia TUBA1A6
    tubulin, alpha 1a
    100(a)
    1 ↔ 1
    GL343198.1(2591245-2598398)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tuba1b1 tubulin, alpha 1b 87.8(n)
    100(a)
      100038123  XM_002935108.2  XP_002935154.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tuba1l21 tubulin, alpha 1, like 2 85.66(n)
    99.78(a)
      573216  NM_001190982.1  NP_001177911.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tba-51 tba-5 69.48(n)
    84.74(a)
      184569  NM_059867.1  NP_492268.1 
    barley
    (Hordeum vulgare)
    Liliopsida Hv.40302 Hordeum vulgare mRNA for alpha-tubulin 3 79.49(n)    AJ132399.1 


    ENSEMBL Gene Tree for TUBA1A (if available)
    TreeFam Gene Tree for TUBA1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TUBA1A gene
    TUBA3C2  TUBA4A2  TUBA1B2  TUBA3E2  TUBA1C2  TUBA82  TUBA3D2  
    Selected SIMAP similar genes for TUBA1A using alignment to 5 protein entries:     TBA1A_HUMAN (see all proteins) (see all similar genes):
    TUBA2    TUBA3C    TUBA3D    TUBA1    TUBA3E    TUBA4A
    TUBA8    TUBA1C    TUBA4B    TUBA1B    DKFZp686L04275    TUBAL3
    MGC16703    TUBB6    TUBB3    TUBB2A    TUBB4A    TUBB2B

    Find genes that share paralogs with TUBA1A           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for TUBA1A (see all 6)
    PGOHUM00000247823 PGOHUM00000261180 PGOHUM00000261294 PGOHUM00000246251 PGOHUM00000246419


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TUBA1A (see all 189)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0393374
    Lissencephaly 3 (LIS3)4--see VAR_0393372 R H mis40--------
    VAR_0393334
    Lissencephaly 3 (LIS3)4--see VAR_0393332 P T mis40--------
    VAR_0393364
    Lissencephaly 3 (LIS3)4--see VAR_0393362 R C mis40--------
    VAR_0393344
    Lissencephaly 3 (LIS3)4--see VAR_0393342 R C mis40--------
    VAR_0393384
    Lissencephaly 3 (LIS3)4--see VAR_0393382 S L mis40--------
    VAR_0393354
    Lissencephaly 3 (LIS3)4--see VAR_0393352 L F mis40--------
    VAR_0393324
    Lissencephaly 3 (LIS3)4--see VAR_0393322 I L mis40--------
    rs122961891,2
    C,F--49411073(+) gaggcC/Tgaggc 3 -- ds50012Minor allele frequency- T:0.50WA CSA 4
    rs122962651,2
    C,F--49411083(+) caagcG/Agatca 3 -- ds50012Minor allele frequency- A:0.50WA CSA 4
    rs79531691,2
    C,F,A,H--49411127(+) TCATGG/ATGAAA 3 -- ds50015Minor allele frequency- A:0.34NA WA CSA 127

    HapMap Linkage Disequilibrium report for TUBA1A (49578579 - 49583107 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TUBA1A: --
    Human Gene Mutation Database (HGMD): TUBA1A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TUBA1A
    DNA2.0 Custom Variant and Variant Library Synthesis for TUBA1A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 602529   
    OMIM disorders: 611603  
    UniProtKB/Swiss-Prot: TBA1A_HUMAN, Q71U36
  • Lissencephaly 3 (LIS3) [MIM:611603]: A classic type lissencephaly associated with psychomotor retardation
    and seizures. Features include agyria or pachygyria or laminar heterotopia, severe mental retardation, motor
    delay, variable presence of seizures, and abnormalities of corpus callosum, hippocampus, cerebellar vermis and
    brainstem. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 6 diseases for TUBA1A:    
    About MalaCards
    lissencephaly 3    distal hereditary motor neuropathy, type ii    treacher collins syndrome 2    pachygyria
    treacher collins syndrome    lissencephaly

    1 disease from the University of Copenhagen DISEASES database for TUBA1A:
    Lissencephaly

    Find genes that share disorders with TUBA1A           About GenesLikeMe

    Genetic Association Database (GAD): TUBA1A
    Human Genome Epidemiology (HuGE) Navigator: TUBA1A (2 documents)

    Export disorders for TUBA1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TUBA1A gene, integrated from 10 sources (see all 190):
    (articles sorted by number of sources associating them with TUBA1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site. (PubMed id 11504633)1, 2, 3 Crabtree D.V.... Adler A.J. (Bioorg. Med. Chem. 2001)
    2. Structural features and restricted expression of a human alpha- tubulin gene. (PubMed id 3839072)1, 2, 3 Hall J.L. and Cowan N.J. (Nucleic Acids Res. 1985)
    3. Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses. (PubMed id 19251251)1, 4 Tomppo L....Peltonen L. (Biol. Psychiatry 2009)
    4. Refining the phenotype of alpha-1a Tubulin (TUBA1A) mutation in patients with classical lissencephaly. (PubMed id 18954413)1, 4 Morris-Rosendahl D.J....Uyanik G. (Clin. Genet. 2008)
    5. Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). (PubMed id 17584854)1, 2 Poirier K.... Chelly J. (Hum. Mutat. 2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions. (PubMed id 6646120)1, 2 Cowan N.J.... Cleveland D.W. (Mol. Cell. Biol. 1983)
    8. Human fibrillarin forms a sub-complex with splicing factor 2- associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes. (PubMed id 14583623)1, 9 Yanagida M.... Takahashi N. (J. Biol. Chem. 2004)
    9. Expanding the spectrum of TUBA1A-related cortical dysgenesis to Polymicrogyria. (PubMed id 22948023)1 Poirier K....Bahi-Buisson N. (Eur. J. Hum. Genet. 2013)
    10. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. (PubMed id 23184937)1 Xie Y....Cong F. (J. Biol. Chem. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 7846 HGNC: 20766 AceView: TUBA3 Ensembl:ENSG00000167552 euGenes: HUgn7846
    ECgene: TUBA1A Kegg: 7846 H-InvDB: TUBA1A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TUBA1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TUBA1A gene:
    Search GeneIP for patents involving TUBA1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of TUBA1A
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for TUBA1A   OriGene RNAi products in human, mouse, rat for TUBA1A  
     OriGene qPCR primer pairs and template standards for TUBA1A   OriGene Protein Over-expression Lysate for TUBA1A  
     OriGene MassSpec for TUBA1A   OriGene clones in human, mouse for TUBA1A  
     OriGene qSTAR qPCR primer pairs in human, mouse for TUBA1A   OriGene Purified Protein for TUBA1A  
     OriGene ORF clones in mouse, rat for TUBA1A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TUBA1A   OriGene Custom Protein Services for TUBA1A  

     
     
     Block miRNA regulation of human, mouse, rat TUBA1A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TUBA1A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TUBA1A Predesigned siRNA for gene silencing in human, mouse, rat TUBA1A
     QuantiFast Probe-based Assays in human, mouse, rat TUBA1A QuantiTect SYBR Green Assays in human, mouse, rat TUBA1A
     Custom PCR Arrays for TUBA1A Search Chromatin IP Primers for TUBA1A
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TUBA1A Search GeneGlobe Interaction Network for TUBA1A
     Regulatory tfbs in TUBA1A promoter
     GenScript Custom Purified and Recombinant Proteins Services for TUBA1A GenScript cDNA clones with any tag delivered in your preferred vector for TUBA1A
     GenScript Custom Assay Services for TUBA1A GenScript Custom overexpressing Cell Line Services for TUBA1A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Antibodies & Assays for TUBA1A 

     Tocris compounds for TUBA1A
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for TUBA1A
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TUBA1A antibodies
     TUBA1A proteins
     TUBA1A lysates
     Antibodies for TUBA1A
     See all of Abcam's Antibodies, Kits and Proteins for TUBA1A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for TUBA1A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TUBA1A
     SwitchGear 3'UTR luciferase reporter plasmids for TUBA1A
     SwitchGear Promoter luciferase reporter plasmids for TUBA1A
     ThermoFisher Antibody for TUBA1A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TUBA1A
     ApexBio compounds for TUBA1A
     Addgene plasmids for TUBA1A
      Search eBioscience for proteins for TUBA1A
      Search eBioscience for elisas for TUBA1A
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for TUBA1A
     antibodies-online antibodies for TUBA1A (53 products)
     antibodies-online kits for TUBA1A (12 products)
     antibodies-online peptides for TUBA1A
     antibodies-online proteins for TUBA1A (12 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TUBA1A gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4