Aliases for TTYH2 Gene
External Ids for TTYH2 Gene
Previous GeneCards Identifiers for TTYH2 Gene
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TTYH2 Gene
TTYH2 (Tweety Family Member 2) is a Protein Coding gene. Diseases associated with TTYH2 include Renal Cell Carcinoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. GO annotations related to this gene include chloride channel activity. An important paralog of this gene is TTYH3.
UniProtKB/Swiss-Prot for TTYH2 Gene
Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.