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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TTTY9B Gene

RNA gene   GIFtS: 21
GCID: GC0YM020746

Testis-Specific Transcript, Y-Linked 9B (Non-Protein Coding)

(Previous names: testis-specific transcript, Y-linked 9B)
  Search for TTTY9B
at
MalaCards
 

Aliases
for TTTY9B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section
Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 5

Aliases
Testis-Specific Transcript, Y-Linked 9B (Non-Protein Coding)1 2     TTTY92
Non-Protein Coding RNA 1321     TTTY9A2
Testis-Specific Transcript, Y-Linked 9B1     TTY92
NCRNA001322     

External Ids:    HGNC: 324251   Entrez Gene: 4250572   Ensembl: ENSG000001310077   
ORGUL members:    fRNAdb10:FR345733      
NCBI13:AF332238    
NONCODE14:n405326      
RNAdb15:LIT2245    

Export aliases for TTTY9B gene to outside databases

Previous GC identifers: GC0YU900277 GC0YM019202 GC0YM020744


Summaries
for TTTY9B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TTTY9B Gene:
This gene is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in
a palindromic region (P4) on chromosome Y. This record represents the more centromeric copy. (provided by RefSeq,
Jul 2008)

GeneCards Summary for TTTY9B Gene: 
TTTY9B (testis-specific transcript, Y-linked 9B (non-protein coding)) is an RNA gene, and is affiliated with the lncRNA class.



fRNAdb sequence ontology for TTTY9B:
antisense_RNA - Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA.

Genomic Views
for TTTY9B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000024.9  NT_011875.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TTTY9B gene promoter:
         IRF-1   STAT5A   Cdc5   NF-E2 p45   E47   SRY   POU2F1   POU2F1a   Hand1   NF-E2   
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTTY9B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Yq11.221   Ensembl cytogenetic band:  Yq11.222   HGNC cytogenetic band: Yq11.221

TTTY9B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTTY9B gene location

GeneLoc information about chromosome Y         GeneLoc Exon Structure

GeneLoc location for GC0YM020746:  view genomic region     (about GC identifiers)

Start:
 20,743,092 bp from pter      End:
 20,752,407 bp from pter
Size:
 9,316 bases      Orientation:
 minus strand

Proteins
for TTTY9B gene

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section
UniProtKB: --

Protein Domains /
Families
for TTTY9B gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
 HGNC Gene Families: 
LNCRNA: Long non-coding RNAs

  --

Function
for TTTY9B gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section
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Pathways & Interactions
for TTTY9B gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTTY9B

Drugs & Compounds
for TTTY9B gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
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Transcripts
for TTTY9B gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for TTTY9B:

Testis-specific transcript, Y-linked 9B (non-protein coding)
Hs.724282  [show with all ESTs]
Unigene Representative Sequence: AF332238
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000433794(uc004fts.1) ENST00000545582
miRNA
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Additional mRNA sequence: 

AF332238.1 NR_002159.1 

2 DOTS entries:

DT.120654305  DT.86855794 

GeneLoc Exon Structure


Expression
for TTTY9B gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for TTTY9B:RNAdb

TTTY9B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
TTTY9B Expression
About this image


Genevestigator expression for TTTY9B

SOURCE GeneReport for Unigene cluster: Hs.724282
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In Situ
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Orthologs
for TTTY9B gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
   --

ENSEMBL Gene Tree for TTTY9B (if available)
TreeFam Gene Tree for TTTY9B (if available)

Paralogs
for TTTY9B gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for TTTY9B gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

2 SNPs in TTTY9B are shown    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr Y posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1997520241,2
----20753329(+) GGCTGC/GAGCTG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for TTTY9B (20743092 - 20752407 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for TTTY9B:    About this table     
Variant IDTypeSubtypePubMed ID
dgv2500e1CNV Complex17122850
esv1670141OTHER Inversion17803354

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Disorders / Diseases
for TTTY9B gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Publications
for TTTY9B gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TTTY9B gene integrated from 9 sources:
(articles sorted by number of sources associating them with TTTY9B)		    Utopia: connect your pdf to the dynamic
world of online information

  1. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. (PubMed id 12815422)1, 3 Skaletsky H.... Page D.C. (2003)
  2. Discrimination of non-protein-coding transcripts from protein-coding mRNA. (PubMed id 17114936)1 Frith M.C.... Mattick J.S. (2006)
  3. (PubMed id 15608161)10 

External Searches for TTTY9B gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing TTTY9B gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 425057 HGNC: 32425 Ensembl:ENSG00000131007 euGenes: HUgn425057 ECgene: TTTY9B
H-InvDB: TTTY9B

Other Databases showing TTTY9B gene

(According to HUGE)
About This Section
   --

Specialized Databases showing TTTY9B gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for TTTY9B Pharmacogenomics, SNPs, Pathways

Intellectual Property
for TTTY9B gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for TTTY9B gene:
Search GeneIP for patents involving TTTY9B

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
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