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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TTTY10 Gene

RNA gene GIFtS: 27
GCID: GC0YM022628

testis-specific transcript, Y-linked 10 (non-protein coding)

(Previous names: testis-specific transcript, Y-linked 10 )

Search for TTTY10
in

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 5

Aliases
Testis-Specific Transcript, Y-Linked 10 (Non-Protein Coding)¹ ²
NCRNA00133¹ ²
TTY10² ³
Testis-Specific Transcript, Y-Linked 10¹

External Ids:	HGNC: 18491¹	Entrez Gene: 246119²	Ensembl: ENSG00000229236⁷	UniProtKB: Q9BZA0³

ORGUL members:	fRNAdb¹⁰:FR028487
	NCBI:AF332239
	NONCODE:n385892
	RNAdb:LIT2238

Export aliases for TTTY10 gene to outside databases

Previous GC identifers: GC0YM021783 GC0YU900012 GC0YM021472 GC0YM020969 GC0YM021036 GC0YM016211

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

fRNAdb sequence ontology for TTTY10:
mature_transcript - A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000024.9 NT_011875.12

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for TTTY10
Other transcription factors

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Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTTY10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Yq11.221 Ensembl cytogenetic band: Yq11.223 HGNC cytogenetic band: Yq11.221

TTTY10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTTY10 gene location

GeneLoc information about chromosome Y GeneLoc Exon Structure

GeneLoc location for GC0YM022628: view genomic region (about GC identifiers)

Start:	22,627,554 bp from pter	End:	22,681,114 bp from pter
Size:	53,561 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TTY10_HUMAN, Q9BZA0 (See protein sequence)

Recommended Name: Putative transcript Y 10 protein

Size: 68 amino acids; 7782 Da

Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for TTTY10: NX_Q9BZA0

TTTY10 Protein expression data from MOPED and PaxDb: --

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q9BZA0

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TTTY10

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

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Search CenterWatch for drugs/clinical trials and news about TTTY10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

Unigene Cluster for TTTY10:

Testis-specific transcript, Y-linked 10 (non-protein coding)

Hs.461175 [show with all ESTs]

Unigene Representative Sequence: NR_001542

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000439472(lincRNA) ENST00000455084(lincRNA)(uc004fuj.1)

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Additional cDNA sequence: NR_001542.1

2 DOTS entries:

DT.97782978 DT.100644829

4 AceView cDNA sequences:

AF332239 NR_001542 BX279861 AA244317

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for TTTY10:RNAdb

TTTY10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
Genevestigator expression for TTTY10

SOURCE GeneReport for Unigene cluster: Hs.461175

SABiosciences Custom PCR Arrays for TTTY10

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for TTTY10 (if available)
TreeFam Gene Tree for TTTY10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr Y pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs9785892^1,2	C,F	--	22634764(+)	`CATTTC/AGCAGA`	1	--	int¹		2		NA WA	4
rs79478142^1,2	C,F	--	22639623(-)	`TGCCTT/GTTGTT`	1	--	int¹		3		NA	8
rs80012685^1,2	C	--	22640541(+)	`CAAATA/CTACGT`	1	--	int¹		0	--	--	--	--
rs78100714^1,2	C	--	22640545(-)	`TCAAAT/CGTGGA`	1	--	int¹		1		NA	4
rs77204100^1,2	C	--	22640554(-)	`ATACTC/GCAAAT`	1	--	int¹		1		NA	4
rs77351526^1,2	C	--	22642054(+)	`AACACA/TTTCAA`	1	--	int¹		0	--	--	--	--
rs77324321^1,2	C	--	22644406(+)	`AGAATA/GGCGAT`	1	--	int¹		0	--	--	--	--
rs76594600^1,2	C	--	22644568(+)	`GCCATA/CCCATT`	1	--	int¹		0	--	--	--	--
rs13303907^1,2	C	--	22644662(+)	`TAGCAA/GAGACT`	1	--	int¹		1		NA	2
rs9786892^1,2	C,F	--	22646728(+)	`CTAACG/ATTATC`	1	--	int¹		2		NA WA	4

HapMap Linkage Disequilibrium report for TTTY10 (22627554 - 22681114 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TTTY10
1 CNV: 31588

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TTTY10 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TTTY10)

Utopia: connect your pdf to the dynamic
world of online information

The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. (PubMed id 12815422)^{1, 2} Skaletsky H.... Page D.C. (2003)
(PubMed id 15608161)¹⁰

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 246119	HGNC: 18491	AceView: TTTY10	Ensembl:ENSG00000229236	euGenes: HUgn246119
ECgene: TTTY10	H-InvDB: TTTY10

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TTTY10	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TTTY10 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TTTY10 gene:
Search GeneIP for patents involving TTTY10

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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TTTY10 Gene

testis-specific transcript, Y-linked 10 (non-protein coding)

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TTTY10 Gene

testis-specific transcript, Y-linked 10 (non-protein coding)

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