TTPA Gene
protein-coding GIFtS: 55
GCID: GC08M064022
|
|
tocopherol (alpha) transfer protein(Previous name: ataxia (Friedreich-like) with vitamin E deficiency )
(Previous symbol: AVED)
| |
Aliases
for TTPA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tocopherol (Alpha) Transfer Protein1 2 | | Alpha-Tocopherol Transfer Protein2 | | AVED1 2 5 | | AlphaTTP1 | | TTP12 5 | | Tocopherol (Alpha) Transfer Protein (Ataxia (Friedreich-Like) With Vitamin EDeficiency)2 | | Ataxia (Friedreich-Like) With Vitamin E Deficiency1 | | Alpha-TTP3 | | ATTP2 | | TPP13 | | Alpha-TTP3 | | |
Export aliases for TTPA gene to outside databasesPrevious GC identifers: GC08M063337 GC08M063913 GC08M063695 GC08M064134 GC08M059459 |
Summaries
for TTPA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TTPA:
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity andaffinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin Ebetween membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins.Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitispigmentosa. (provided by RefSeq, Nov 2009)
UniProtKB/Swiss-Prot: TTPA_HUMAN, P49638Function: Binds alpha-tocopherol and enhances its transfer between separate membranes
Gene Wiki entry for TTPA (Alpha-tocopherol transfer protein)
|
Genomic Views
for TTPA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008183.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TTPA gene promoter:
LHX3b/Lhx3b FOXD1 MEF-2A PPAR-alpha FAC1 Cart-1 LHX3a/Lhx3a aMEF-2 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for TTPA
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTPA |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q12.3 Ensembl cytogenetic band: 8q12.3 HGNC cytogenetic band: 8q12.3TTPA Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M064022: view genomic region
(about GC identifiers)
Start:
|
63,961,112 bp from pter |
End:
|
63,998,612 bp from pter |
Size:
|
37,501 bases |
Orientation:
|
minus strand |
|
Proteins
for TTPA gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TTPA_HUMAN, P49638 (See
protein sequence)Recommended Name: Alpha-tocopherol transfer protein Size: 278 amino acids; 31750 Da
Subcellular location: Cytoplasm
3 PDB 3D structures from  and Proteopedia  for TTPA:1OIP (3D)
1OIZ (3D)
1R5L (3D)
Secondary accessions: Q71V64Explore the universe of human proteins at neXtProt for TTPA: NX_P49638
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49638
TTPA Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000361.1
ENSEMBL proteins: ENSP00000260116
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
TTPA for ontologies About GeneDecksing
TTPA Antibody Products:
Assay Products for TTPA: |
Protein
Domains /
Families
for TTPA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TTPA for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49638ProtoNet protein and cluster: P49638 3 Blocks protein families: IPB001071 Cellular retinaldehyde-binding protein signature IPB001251 Cellular retinaldehyde-binding (CRAL)/Triple function domain (TRIO) IPB008273 Cellular retinaldehyde-binding/triple function
UniProtKB/Swiss-Prot: TTPA_HUMAN, P49638Similarity: Contains 1 CRAL-TRIO domain |
Function
for TTPA gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TTPA_HUMAN, P49638Function: Binds alpha-tocopherol and enhances its transfer between separate membranes Genatlas biochemistry entry for TTPA:alpha-tocopherol transfer protein
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTPA (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTPA
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTPA |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TTPA for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Ttpatm1Hsz for TTPA
8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Ttpa):
TTPA for phenotypes About GeneDecksing
|
Pathways & Interactions
for TTPA gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTPA
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
3 Interacting proteins for TTPA (P496383 ENSP000002601164) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
TTPA for ontologies About GeneDecksing
|
Drugs & Compounds
for TTPA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TTPA for compounds About GeneDecksing
 Browse Tocris compounds for TTPA
1 HMDB Compound for TTPA About this table
2 DrugBank Compounds for TTPA About this table
10/13 Novoseek chemical compound relationships for TTPA gene (see all 13) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| alpha tocopherol |
92.5 |
321 |
20368946 (5), 14531858 (5), 20187127 (4), 9356467 (4) (see all 99) |
| tocopherol |
91.1 |
56 |
18458085 (3), 15318806 (2), 15753136 (2), 15753158 (2) (see all 28) |
| vitamin-e |
88.6 |
139 |
10082886 (3), 10727494 (3), 20368946 (3), 18458085 (3) (see all 57) |
| delta-tocopherol |
75.3 |
1 |
16491383 (1) |
| alpha-tocopherol quinone |
64.6 |
3 |
9801162 (2) |
| lipid |
31.2 |
6 |
19458973 (1), 12767229 (1), 18458085 (1), 16430203 (1) |
| phosphatidylinositol |
25.7 |
3 |
11226224 (1), 12767229 (1) |
| cholesterol |
13.9 |
3 |
9356467 (1), 20387845 (1), 10540874 (1) |
| atp |
0 |
1 |
17252538 (1) |
| oxygen |
0 |
3 |
10867030 (1), 18511174 (1) |
Search CenterWatch for drugs/clinical trials and news about TTPA
|
Transcripts
for TTPA gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TTPA gene: NM_000370.3 Unigene Cluster for TTPA: Tocopherol (alpha) transfer protein Hs.69049 [show with all ESTs]Unigene Representative Sequence: NM_0003702 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000521138 ENST00000260116(uc003xux.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTPA (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTPA
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TTPA (NM_000370) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TTPA | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTPA |
Additional cDNA sequence: BC041784.1 BC058000.1 D49488.1 U21938.1 2 DOTS entries: DT.101976708 DT.204951 18 AceView cDNA sequences: D49488 BM463341 BC058000 BX283648 NM_000370 BG614543 BX101071 AL119672 BC041784 AW043604 U21938 H68464 BE971379 BG427807 N56849 H68830 AA703331 BG400921
GeneLoc Exon Structure
|
Expression
for TTPA gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TTPA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTCACAAA
About this image
See TTPA Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TTPA
SOURCE GeneReport for Unigene cluster: Hs.69049
SABiosciences Custom PCR Arrays for TTPA
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTPA
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTPA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTPA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTPA | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTPA |
Orthologs
for TTPA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TTPA gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ttpa1 , 5 |
tocopherol (alpha) transfer protein1, 5 |
86.57(n)1
89.21(a)1 |
|
4 (7.76 cM)5
505001 NM_015767.31 NP_056582.11
200079385 |
chicken
(Gallus gallus) |
Aves |
TTPA1 |
tocopherol (alpha) transfer protein |
74.43(n)
73.66(a) |
|
771074 XM_001234375.1 XP_001234376.1 |
lizard
(Anolis carolinensis) |
Reptilia |
TTPA6 |
-- |
68(a) |
1 ↔ 1 |
4(29431059-29450489) |
zebrafish
(Danio rerio) |
Actinopterygii |
wufd44e052 |
wufd44e05 |
76.8(n) |
|
325906 BC055617.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG102373 |
retinal binding |
32(a) |
|
37E1 -- |
ENSEMBL Gene Tree for TTPA (if available)
TreeFam Gene Tree for TTPA (if available) |
Paralogs
for TTPA gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TTPA gene
- TTPAL2 RLBP12 CLVS22 CLVS12
5 SIMAP similar genes for TTPA using alignment to 1 protein entry: TTPA_HUMAN:CLVS1 CLVS2 RLBP1 DKFZp686E0870 TTPAL
TTPA for paralogs About GeneDecksing
|
Genomic Variants
for TTPA gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TTPA (63961112 - 63998612 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TTPA: --
Human Gene Mutation Database (HGMD): TTPA
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTPA |
|
Disorders
/ Diseases
for TTPA gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TTPA for disorders About GeneDecksing
OMIM gene information: 600415
OMIM disorders: 277460
UniProtKB/Swiss-Prot: TTPA_HUMAN, P49638
Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED) [MIM:277460]. AVED is anautosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathythat resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E
20/31  diseases for TTPA (see all 31): About MalaCardsataxia retinitis pigmentosa ataxia with isolated vitamin e deficiency distal hereditary motor neuropathy
spinocerebellar ataxia type 8 retinitis spinocerebellar ataxia friedreich ataxia
abetalipoproteinemia autosomal recessive disease apraxia myocardial infarction
acute myocardial infarction spinocerebellar degeneration cerebellar ataxia ataxia telangiectasia
peripheral neuropathy protein s deficiency neurodegenerative disease hereditary ataxia
5 diseases from the University of Copenhagen DISEASES database for TTPA:Friedreich ataxia Abetalipoproteinemia Cerebellar ataxia Apraxia
DOID:4019 10/15 Novoseek disease relationships for TTPA gene (see all 15) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| vitamin e deficiency |
96.6 |
56 |
10082886 (3), 15300460 (2), 18458655 (2), 20368946 (2) (see all 34) |
| friedreich ataxia |
78.3 |
8 |
10996881 (1), 9463307 (1), 12470185 (1), 17112370 (1) (see all 5) |
| abetalipoproteinemia |
71.7 |
2 |
10082886 (1) |
| spinocerebellar ataxias |
57.6 |
2 |
10082886 (1), 16491383 (1) |
| retinitis pigmentosa |
56.3 |
10 |
9189046 (2), 11754917 (2), 10727494 (2), 8965888 (1) (see all 5) |
| protein deficiency |
53.6 |
2 |
9645052 (1), 9931538 (1) |
| neurodegenerative diseases |
44.2 |
9 |
12470185 (1), 15300460 (1), 17628170 (1), 10082886 (1) (see all 5) |
| apraxias |
31.9 |
2 |
17112370 (1) |
| neurodegeneration |
29.1 |
2 |
14642382 (1), 17628171 (1) |
| neurological disorders |
29.1 |
3 |
15753133 (1), 20368946 (1), 16819822 (1) |
GeneTests: TTPA
Ataxia with Vitamin E Deficiency
Human Genome Epidemiology (HuGE) Navigator: TTPA (55 documents)
Export disorders for TTPA gene to outside databases
|
Publications
for TTPA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TTPA gene, integrated from 9 sources (see all 129):
(articles sorted by number of sources associating them with TTPA) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. (PubMed id 7887897)1, 2, 3, 9 Arita M.... Inoue K. (1995)
- Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. (PubMed id 7719340)1, 2, 3, 9 Ouahchi K.... Koenig M. (1995)
- Human alpha-tocopherol transfer protein: gene structure and mutations in familial vitamin E deficiency. (PubMed id 8602747)1, 2, 9 Hentati A.... Siddique T. (1996)
- Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein. (PubMed id 7566022)1, 2, 9 Gotoda T.... Yamada N. (1995)
- The molecular basis of vitamin E retention: structure of human alpha- tocopherol transfer protein. (PubMed id 12899840)1, 2, 9 Meier R.... Stocker A. (2003)
- Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPA gene in Italian families. (PubMed id 15300460)1, 2, 9 Mariotti C.... Di Donato S. (2004)
- Ataxia with isolated vitamin E deficiency: heterogeneity of mutations and phenotypic variability in a large number of families. (PubMed id 9463307)1, 2, 9 Cavalier L.... Koenig M. (1998)
- Molecular determinants of heritable vitamin E deficiency. (PubMed id 15065857)1, 2, 9 Morley S.... Manor D. (2004)
- Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency. (PubMed id 14657365)1, 2, 9 Min K.C.... Hendrickson W.A. (2003)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for TTPA gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TTPA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TTPA gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TTPA gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TTPA | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/TTPA |
|
| | |
About This Section
| Patent Information for TTPA gene:
Search GeneIP for patents involving TTPA
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TTPA gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TTPA | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTPA | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTPA | | | OriGene Protein Over-expression Lysate for TTPA | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TTPA | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTPA | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTPA | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TTPA | | OriGene Custom Protein Services for TTPA | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TTPA | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTPA | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTPA | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTPA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTPA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTPA |
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| | | | Search Tocris compounds for TTPA |
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 | | | TTPA Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTPA |
|  |  |  | | | | Search ThermoFisher Antibodies for TTPA |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTPA |
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