Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TTLL8 Gene

protein-coding   GIFtS: 31
GCID: GC22M050453

Tubulin Tyrosine Ligase-Like Family, Member 8

  Search for TTLL8
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tubulin Tyrosine Ligase-Like Family, Member 81 2
Tubulin--Tyrosine Ligase-Like Protein 82 3
Protein Monoglycylase TTLL82
EC 6.3.2.-3

External Ids:    HGNC: 340001   Entrez Gene: 1647142   Ensembl: ENSG000001388927   UniProtKB: A6PVC23   

Export aliases for TTLL8 gene to outside databases

Previous GC identifers: GC22M048795 GC22M033351


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TTLL8 Gene: 
TTLL8 (tubulin tyrosine ligase-like family, member 8) is a protein-coding gene. GO annotations related to this gene include tubulin-tyrosine ligase activity and protein-glycine ligase activity, initiating. An important paralog of this gene is TTLL4.

UniProtKB/Swiss-Prot: TTLL8_HUMAN, A6PVC2
Function: Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on
the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a
preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A,
ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single
glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation
reaction (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TTLL8 gene promoter:
         Max   Max1   p53   HNF-1   PPAR-gamma2   Cdc5   HNF-1A   En-1   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TTLL8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTLL8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.33   Ensembl cytogenetic band:  22q13.33   HGNC cytogenetic band: 22q13.33

TTLL8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTLL8 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M050453:  view genomic region     (about GC identifiers)

Start:
50,453,552 bp from pter      End:
50,495,364 bp from pter
Size:
41,813 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TTLL8_HUMAN, A6PVC2 (See protein sequence)
Recommended Name: Protein monoglycylase TTLL8  
Size: 850 amino acids; 94676 Da
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cell projection, cilium (By similarity). Cytoplasm,
cytoskeleton, cilium axoneme (By similarity)

Explore the universe of human proteins at neXtProt for TTLL8: NX_A6PVC2

Explore proteomics data for TTLL8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A6PVC2

  • TTLL8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TTLL8 Protein Expression

    ENSEMBL proteins: 
     ENSP00000392252   ENSP00000266182   ENSP00000387509  

    Human Recombinant Protein Products for TTLL8: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TTLL8
    GenScript Custom Purified and Recombinant Proteins Services for TTLL8
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TTLL8 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005874microtubule IEA--
    GO:0005929cilium ISS--
    GO:0015630microtubule cytoskeleton ISS--
    GO:0035085cilium axoneme ISS--

    TTLL8 for ontologies           About GeneDecksing



    TTLL8 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TTLL8
    GenScript Custom Superior Antibodies Services for TTLL8
    Novus Biologicals TTLL8 Antibody
    Abcam antibodies for TTLL8
    Cloud-Clone Corp. Antibodies for TTLL8 
    Search ThermoFisher Antibodies for TTLL8
    Search LSBio for Antibodies for TTLL8 

    Assay Products for TTLL8: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TTLL8
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TTLL8
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TTLL8 
    Cloud-Clone Corp. CLIAs for TTLL8


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TTLL: Tubulin tyrosine ligase-like family

    1 InterPro protein domain:
     IPR004344 Tub_tyr_ligase

    Graphical View of Domain Structure for InterPro Entry A6PVC2

    ProtoNet protein and cluster: A6PVC2

    UniProtKB/Swiss-Prot: TTLL8_HUMAN, A6PVC2
    Similarity: Contains 1 TTL domain


    TTLL8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TTLL8_HUMAN, A6PVC2
    Function: Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on
    the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a
    preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A,
    ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single
    glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation
    reaction (By similarity)

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004835tubulin-tyrosine ligase activity ----
    GO:0016989sigma factor antagonist activity ----
    GO:0070735protein-glycine ligase activity ISS--
    GO:0070736protein-glycine ligase activity, initiating ISS--
         
    TTLL8 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TTLL8:
     Large cells 

         1 MGI phenotypic allele for Ttll8 (no phenotypes)

    TTLL8 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ttll8tm1Lex for TTLL8

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TTLL8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TTLL8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TTLL8 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTLL8 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL8
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TTLL8
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TTLL8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTLL8

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TTLL8
    Sirion Biotech Customized adenovirus for overexpression of TTLL8

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TTLL8 (see all 3)
    OriGene ORF clones in mouse, rat for TTLL8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for TTLL8
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTLL8
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TTLL8
    Sirion Biotech Customized lentivirus for stable overexpression of TTLL8 
                         Customized lentivirus expression plasmids for stable overexpression of TTLL8 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TTLL8
    Search LifeMap BioReagents cell lines for TTLL8
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTLL8

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006464cellular protein modification process ----
    GO:0018094protein polyglycylation ISS--

    TTLL8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TTLL8

    Search CenterWatch for drugs/clinical trials and news about TTLL8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TTLL8 gene: 
    NM_001080447.1  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000433387 ENST00000477219 ENST00000266182 ENST00000440475
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL8
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TTLL8
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TTLL8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTLL8
    Clone
    Products:
         
    OriGene clones in human, mouse for TTLL8 (see all 3)
    OriGene ORF clones in mouse, rat for TTLL8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for TTLL8
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTLL8
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TTLL8
    Sirion Biotech Customized lentivirus for stable overexpression of TTLL8 
                         Customized lentivirus expression plasmids for stable overexpression of TTLL8 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TTLL8
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTLL8
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTLL8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTLL8

    1 AceView cDNA sequence:

    H55115 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TTLL8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TTLL8 Expression
    About this image


    See TTLL8 Protein Expression from SPIRE MOPED and PaxDB    SABiosciences Custom PCR Arrays for TTLL8
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TTLL8
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTLL8
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTLL8
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTLL8
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TTLL8 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ttll81 , 5 tubulin tyrosine ligase-like family, member 81, 5 73.08(n)1
    66.84(a)1
      15 (44.39 cM)5
    2395911  NM_172818.31  NP_766406.21 
     888906335 
    lizard
    (Anolis carolinensis)
    Reptilia TTLL86
    Uncharacterized protein
    64(a)
    1 ↔ 1
    GL344581.1(308-6057)
    fruit fly
    (Drosophila melanogaster)
    Insecta TTLL3B6
    TTLL3A6
    Tubulin tyrosine ligase-like 3A
    23(a)
    21(a)
    many ↔ many
    many ↔ many
    2L(6732866-6736149)
    2L(6736449-6740176)


    ENSEMBL Gene Tree for TTLL8 (if available)
    TreeFam Gene Tree for TTLL8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TTLL8 gene
    TTLL42  TTLL102  ENSG000002611472  TTLL32  TTLL12  TTLL52  TTLL112  TTLL92  
    TTLL72  TTLL62  TTL2  TTLL22  TTLL132  ARPC4-TTLL32  
    1 SIMAP similar gene for TTLL8 using alignment to 3 protein entries:     TTLL8_HUMAN (see all proteins):
    TTLL3

    TTLL8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1052 SNPs in TTLL8 are shown (see all 1052)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58459121,2
    C--33369361(+) GCCCAC/-CGCAC 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs716493341,2
    C--33373378(+) TTAAC-/TTTTTT 1 -- int10--------
    rs96283151,2,4
    C,F,A,H--33377848(+) GTCCTC/TCACGG 2 K E mis1 ese332Minor allele frequency- N:0.00EA NA NS CSA WA EU 3958
    rs345001801,2
    C--33384284(+) AAAAA-/GTGTGTG 1 -- int10--------
    rs1394178781,2
    C--33394721(+) GGTGCA/GCGCCA 1 -- us2k10--------
    rs1851565331,2
    C--33394776(+) GCTGCA/GGCCCC 1 -- us2k10--------
    rs1810524261,2
    --34408261(+) GGTGCA/GCGCCT 1 -- ds50010--------
    rs1509321711,2
    C--34408438(+) ATCCCA/GACACT 1 -- ds50010--------
    rs1392923781,2
    --34408480(+) CTTAGA/GAGTTT 1 -- ds50010--------
    rs1387962501,2
    C--34408612(+) GAACCC/TGGGAT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for TTLL8 (50453552 - 50495364 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TTLL8: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TTLL8
    DNA2.0 Custom Variant and Variant Library Synthesis for TTLL8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TTLL8 for disorders           About MalaCards

    TTLL8 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TTLL8

    Export disorders for TTLL8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TTLL8 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TTLL8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Tubulin polyglutamylase enzymes are members of the TTL domain protein family. (PubMed id 15890843)1, 3 Janke C.... Edde B. (2005)
    2. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    3. The DNA sequence of human chromosome 22. (PubMed id 10591208)2 Dunham I....O'Brien K.P. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 164714 HGNC: 34000 AceView: LOC164714.2 Ensembl:ENSG00000138892 euGenes: HUgn164714
    ECgene: TTLL8 H-InvDB: TTLL8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TTLL8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TTLL8 gene:
    Search GeneIP for patents involving TTLL8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TTLL8  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TTLL8  
     OriGene qSTAR qPCR primer pairs in human, mouse for TTLL8   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TTLL8   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TTLL8   OriGene Custom Protein Services for TTLL8  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TTLL8
     QIAGEN SeqTarget long-range PCR primers for resequencing TTLL8
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTLL8
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTLL8
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTLL8
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTLL8
     GenScript Custom Purified and Recombinant Proteins Services for TTLL8 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TTLL8
     GenScript Custom Assay Services for TTLL8 GenScript Custom Superior Antibodies Services for TTLL8
     GenScript Custom overexpressing Cell Line Services for TTLL8 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TTLL8 promoter
     Search Chromatin IP Primers for TTLL8
     RT2 qPCR Primer Assay in human, mouse, rat TTLL8
     Search GNC Networks for TTLL8
     SABiosciences Custom PCR Arrays for TTLL8
     Search Tocris compounds for TTLL8
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TTLL8 antibodies
     Antibodies for TTLL8
     See all of Abcam's Antibodies, Kits and Proteins for TTLL8
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for TTLL8
     Antibodies for TTLL8
     ELISAs for TTLL8
     CLIAs for TTLL8
     Search LifeMap BioReagents cell lines for TTLL8
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL8
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TTLL8
     Browse SwitchGear Promoter luciferase reporter plasmids for TTLL8
     Search ThermoFisher Antibodies for TTLL8
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TTLL8
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TTLL8
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TTLL8
    Customized:
     lentivirus for stable overexpression of TTLL8
     lentivirus expression plasmids for stable overexpression of TTLL8
     adenovirus for overexpression of TTLL8
     Search LSBio for Antibodies for TTLL8
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TTLL8 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4