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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TTLL7 Gene

protein-coding GIFtS: 45
GCID: GC01M084330

tubulin tyrosine ligase-like family, member 7

Explore 2 diseases affiliated with
TTLL7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tubulin Tyrosine Ligase-Like Family, Member 7¹ ²		RP5-836J3.2²
Testis Development Protein NYD-SP30² ³		Tubulin Polyglutamylase TTLL7²
Tubulin--Tyrosine Ligase-Like Protein 7² ³		EC 6.-.-.-³
FLJ23033¹

External Ids:	HGNC: 26242¹	Entrez Gene: 79739²	Ensembl: ENSG00000137941⁷	UniProtKB: Q6ZT98³

Export aliases for TTLL7 gene to outside databases

Previous GC identifers: GC01M084048 GC01M082451

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TTLL7_HUMAN, Q6ZT98

Function: Polyglutamylase which preferentially modifies beta-tubulin. Involved in the side-chain initiation step of the

polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TTLL7 gene promoter:
FOXF2 POU2F2 NF-AT POU2F2C POU2F1 NF-AT2 POU2F1a STAT3 POU2F2B NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TTLL7 promoter sequence

Search SABiosciences Chromatin IP Primers for TTLL7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTLL7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.1 Ensembl cytogenetic band: 1p31.1 HGNC cytogenetic band: 1p31.1

TTLL7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTLL7 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M084330: view genomic region (about GC identifiers)

Start:	84,330,711 bp from pter	End:	84,464,833 bp from pter
Size:	134,123 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TTLL7_HUMAN, Q6ZT98 (See protein sequence)

Recommended Name: Tubulin polyglutamylase TTLL7

Size: 887 amino acids; 102999 Da

Subcellular location: Cell projection, cilium (By similarity). Cytoplasm, cytoskeleton, cilium basal body (By

similarity). Cell projection, dendrite (By similarity). Perikaryon (By similarity). Note=In cells with primary cilia,

found in both cilia and basal bodies. In neuronal cells, found in dendrites and perikaryon (By similarity)

Secondary accessions: Q5TAX8 Q5TAX9 Q6P990 Q86YS1 Q9H5U4

Alternative splicing: 3 isoforms: Q6ZT98-1 Q6ZT98-2 Q6ZT98-3

Explore the universe of human proteins at neXtProt for TTLL7: NX_Q6ZT98

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZT98

TTLL7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_078962.4

ENSEMBL proteins:

ENSP00000260505 ENSP00000434146 ENSP00000435334 ENSP00000432921

Human Recombinant Protein Products:

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	Uscn Proteins for TTLL7

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005929	cilium	IEA	--
GO:0005932	microtubule basal body	IEA	--
GO:0030425	dendrite	IEA	--
GO:0043204	perikaryon	IEA	--

TTLL7 for ontologies About GeneDecksing

TTLL7 Antibody Products:

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	Uscn Antibodies for TTLL7
	Search ThermoFisher Antibodies for TTLL7

Assay Products for TTLL7:

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	GenScript Custom Assay Services for TTLL7
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	Uscn ELISAs and CLIAs for TTLL7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TTLL7 for domains About GeneDecksing

1 InterPro domain/family:

IPR004344 Tub_tyr_ligase

Graphical View of Domain Structure for InterPro Entry Q6ZT98

ProtoNet protein and cluster: Q6ZT98

1 Blocks protein family: IPB004344 Tubulin-tyrosine ligase

UniProtKB/Swiss-Prot: TTLL7_HUMAN, Q6ZT98

Similarity: Belongs to the tubulin--tyrosine ligase family

Similarity: Contains 1 TTL domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TTLL7_HUMAN, Q6ZT98

Function: Polyglutamylase which preferentially modifies beta-tubulin. Involved in the side-chain initiation step of the

polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity)

Enzyme Number (IUBMB): EC 6.-.-.-¹

miRNA Products:		OriGene 3'-UTR Clone: TTLL7 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL7
		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate TTLL7 (see all 11):
		hsa-miR-30c hsa-miR-548p hsa-miR-200a hsa-miR-545 hsa-miR-30d hsa-miR-141 hsa-miR-1184 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: TTLL7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTLL7 OriGene shRNA RFP: TTLL7 OriGene siRNA: TTLL7
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Gene Editing
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TTLL7
		Search LifeMap BioReagents cell lines for TTLL7

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL7

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004835	tubulin-tyrosine ligase activity	IEA	--

TTLL7 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for TTLL7:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TTLL7

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006464	cellular protein modification process	IEA	--
GO:0007399	nervous system development	IEA	--
GO:0030154	cell differentiation	IEA	--

TTLL7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TTLL7
Search CenterWatch for drugs/clinical trials and news about TTLL7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TTLL7 gene:

NM_024686.4

Unigene Cluster for TTLL7:

Tubulin tyrosine ligase-like family, member 7

Hs.445826 [show with all ESTs]

Unigene Representative Sequence: NM_024686

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000260505(uc001djc.3) ENST00000474957(uc001djf.3) ENST00000477524(uc001djd.3 uc001djg.3)

ENST00000488014(uc001dje.3) ENST00000480174(uc001djb.3) ENST00000472688

ENST00000480533 ENST00000472937 ENST00000485638 ENST00000464289 ENST00000474702

ENST00000482783 ENST00000467670

miRNA Products:		OriGene 3'-UTR Clone: TTLL7 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL7
		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate TTLL7 (see all 11):
		hsa-miR-30c hsa-miR-548p hsa-miR-200a hsa-miR-545 hsa-miR-30d hsa-miR-141 hsa-miR-1184 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: TTLL7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTLL7 OriGene shRNA RFP: TTLL7 OriGene siRNA: TTLL7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTLL7

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTLL7 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTLL7 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TTLL7 (NM_024686)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTLL7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTLL7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTLL7 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTLL7

Additional cDNA sequence:

AK026686.1 AK094174.1 AK126792.1 AK225574.1

15 DOTS entries:

DT.210355 DT.101963397 DT.101981583 DT.99997248 DT.99930437 DT.95196105 DT.100000988 DT.121416140

DT.91638479 DT.92420183 DT.100781135 DT.101981584 DT.121416125 DT.40279508 DT.91744409

24/102 AceView cDNA sequences (see all 102):

AA626351 BC048970 AA339154 CA433870 AI298905 AA322804 AA234693 Z43975

BU167859 BX103262 AI374651 CA503234 AL118758 BF514197 AA417343 AK126792

Z44270 BC032829 AA461320 AY170843 BC028350 N62893 Z40034 Z40229

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TTLL7 (see all 8) About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20	^	21a	·
SP1:			-		-		-		-		-		-		-		-		-
SP2:					-								-
SP3:																																															-		-
SP4:													-
SP5:

ExUns:	21b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for TTLL7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TTLL7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAAAATTGT

About this image

TTLL7 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TTLL7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TTLL7

SOURCE GeneReport for Unigene cluster: Hs.445826

UniProtKB/Swiss-Prot: TTLL7_HUMAN, Q6ZT98

Tissue specificity: Highly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus

and cerebellum

SABiosciences Custom PCR Arrays for TTLL7

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTLL7

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for TTLL7 gene from 3/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	TTLL7¹	tubulin tyrosine ligase-like family, member 7	75.39(n) 76.56(a)		424543 XM_422380.3 XP_422380.2
lizard (Anolis carolinensis)	Reptilia	TTLL7⁶	--	73(a)	1 ↔ 1	GL343194.1(9217251-9296375)
zebrafish (Danio rerio)	Actinopterygii	ttll7¹	tubulin tyrosine ligase-like family, member 7	70.6(n) 80.2(a)		565243 NM_001080595.1 NP_001074064.1

ENSEMBL Gene Tree for TTLL7 (if available)
TreeFam Gene Tree for TTLL7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TTLL7 gene

TTLL10² TTLL4² TTLL3² TTLL1² TTLL5² TTLL11² TTLL9² TTLL6²

TTL² TTLL8² TTLL2² TTLL13² ARPC4-TTLL3²

3 SIMAP similar genes for TTLL7 using alignment to 5 protein entries: TTLL7_HUMAN (see all proteins):

TTLL11 TTLL13 TTLL6

TTLL7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs67743726^1,2	C	--	82550005(+)	`TTCTC-/AA ACTTGAATGT`	1	--	int¹		0	--	--	--	--
rs144673121^1,2		--	84334666(+)	`TTATTA/TTTTTT`	1	--	ds500¹		0	--	--	--	--
rs183653754^1,2		--	84334705(+)	`CCAGGC/GTAGAA`	1	--	ds500¹		0	--	--	--	--
rs189094077^1,2		--	84334740(+)	`TGCAAC/TCTCCG`	1	--	ds500¹		0	--	--	--	--
rs6666984^1,2	C,F,H,	--	84334804(+)	`CAAGCG/ACTTAC`	1	--	ds500¹		9		NA WA CSA EA	369
rs12127657^1,2		--	84334938(+)	`acaggC/Tgtgag`	1	--	ds500¹ ese³		0	--	--	--	--
rs6701191^1,2	C,	--	84334956(+)	`gcccaC/GccTGT`	1	--	ds500¹ ese³		0	--	--	--	--
rs116174042^1,2		--	84334986(+)	`TATGAT/CCTCAC`	1	--	ds500¹		1		NA	120
rs151213831^1,2		--	84335165(+)	`CTAAAC/TCTTTT`	1	--	ut3¹		0	--	--	--	--
rs192886025^1,2		--	84335235(+)	`TTTCAA/GGTCAA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TTLL7 (84330711 - 84464833 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TTLL7
3 Indels: 84340 74550 64096

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTLL7

DNA2.0 Custom Variant and Variant Library Synthesis for TTLL7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TTLL7 for disorders About GeneDecksing

2 diseases for TTLL7: About MalaCards

malaria neuronitis

Export disorders for TTLL7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TTLL7 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with TTLL7)

Utopia: connect your pdf to the dynamic
world of online information

The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
Tubulin polyglutamylase enzymes are members of the TTL domain protein family. (PubMed id 15890843)^{1, 3} Janke C.... Edde B. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Genome-wide scan of copy number variation in late-onse t Alzheimer's disease. (PubMed id 20061627)¹ Heinzen E.L....Goldstein D.B. (2010)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)
TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites. (PubMed id 16901895)² Ikegami K....Setou M. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 79739	HGNC: 26242	AceView: FLJ23033	Ensembl:ENSG00000137941	euGenes: HUgn79739
ECgene: TTLL7	H-InvDB: TTLL7

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TTLL7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TTLL7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TTLL7 gene:
Search GeneIP for patents involving TTLL7

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
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	Browse OriGene Antibodies		OriGene shRNA RFP for TTLL7
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTLL7		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTLL7
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TTLL7
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTLL7
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	GenScript Custom Purified and Recombinant Proteins Services for TTLL7		GenScript cDNA clones with any tag delivered in your preferred vector for TTLL7
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL7

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTLL7

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes TTLL7 gene at Home site.

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TTLL7 Gene

tubulin tyrosine ligase-like family, member 7

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for TTLL7 gene

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for TTLL7 gene

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for TTLL7 gene

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TTLL7 Gene

tubulin tyrosine ligase-like family, member 7

Aliasesfor TTLL7 gene

Summariesfor TTLL7 gene

Genomic Viewsfor TTLL7 gene

Proteinsfor TTLL7 gene

Protein Domains /Familiesfor TTLL7 gene

Functionfor TTLL7 gene

Pathways & Interactionsfor TTLL7 gene

Drugs & Compoundsfor TTLL7 gene

Transcriptsfor TTLL7 gene

Expression for TTLL7 gene

Orthologsfor TTLL7 gene

Paralogsfor TTLL7 gene

Genomic Variantsfor TTLL7 gene

Disorders / Diseasesfor TTLL7 gene

Publicationsfor TTLL7 gene

External Searches for TTLL7 gene

Genome Databases showing TTLL7 gene

Other Databases showing TTLL7 gene

Specialized Databases showing TTLL7 gene

Intellectual Propertyfor TTLL7 gene

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Aliases
for TTLL7 gene

Summaries
for TTLL7 gene

Genomic Views
for TTLL7 gene

Proteins
for TTLL7 gene

Protein Domains /
Families
for TTLL7 gene

Function
for TTLL7 gene

Pathways & Interactions
for TTLL7 gene

Drugs & Compounds
for TTLL7 gene

Transcripts
for TTLL7 gene

Expression
for TTLL7 gene

Orthologs
for TTLL7 gene

Paralogs
for TTLL7 gene

Genomic Variants
for TTLL7 gene

Disorders / Diseases
for TTLL7 gene

Publications
for TTLL7 gene

Intellectual Property
for TTLL7 gene

Products
for TTLL7 gene