Aliases for TTLL3 Gene
External Ids for TTLL3 Gene
Previous GeneCards Identifiers for TTLL3 Gene
GeneCards Summary for TTLL3 Gene
TTLL3 (Tubulin Tyrosine Ligase-Like Family Member 3) is a Protein Coding gene. Diseases associated with TTLL3 include colorectal cancer. Among its related pathways are Fcgamma receptor (FCGR) dependent phagocytosis and Fcgamma receptor (FCGR) dependent phagocytosis. GO annotations related to this gene include protein-glycine ligase activity and protein-glycine ligase activity, initiating. An important paralog of this gene is TTLL8.
UniProtKB/Swiss-Prot for TTLL3 Gene
Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.