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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TTLL3 Gene

protein-coding GIFtS: 44
GCID: GC03P009851

tubulin tyrosine ligase-like family, member 3

Search for TTLL3
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tubulin Tyrosine Ligase-Like Family, Member 3¹ ²
HOTTL¹ ² ³
Tubulin--Tyrosine Ligase-Like Protein 3² ³
DKFZP434B103¹
Tubulin Monoglycylase TTLL3²
EC 6.3.2.-³

External Ids:	HGNC: 24483¹	Entrez Gene: 26140²	Ensembl: ENSG00000214021⁷	UniProtKB: Q9Y4R7³

Export aliases for TTLL3 gene to outside databases

Previous GC identifers: GC03P009836 GC03P009810 GC03P009811 GC03P009749 GC03P009813 GC03P009850 GC03P009788

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TTLL3_HUMAN, Q9Y4R7

Function: Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl

groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the

side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side

chains. Not involved in elongation step of the polyglycylation reaction

Gene Wiki entry for TTLL3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_022517.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TTLL3 gene promoter:
NF-1 p300 HEN1 AREB6 E2F-1 E2F COMP1 SEF-1 (1) TGIF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TTLL3 promoter sequence

Search SABiosciences Chromatin IP Primers for TTLL3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTLL3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.3 Ensembl cytogenetic band: 3p25.3 HGNC cytogenetic band: 3p25.3

TTLL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTLL3 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P009851: view genomic region (about GC identifiers)

Start:	9,849,770 bp from pter	End:	9,896,822 bp from pter
Size:	47,053 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TTLL3_HUMAN, Q9Y4R7 (See protein sequence)

Recommended Name: Tubulin monoglycylase TTLL3

Size: 772 amino acids; 87414 Da

Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cell projection, cilium (By similarity). Cytoplasm,

cytoskeleton, cilium axoneme (By similarity)

Secondary accessions: Q4KMS8 Q6AWA3 Q6ZU95 Q8NDN8 Q96GG8 Q9H876 Q9UI99

Alternative splicing: 4 isoforms: Q9Y4R7-1 Q9Y4R7-2 Q9Y4R7-5 Q9Y4R7-6 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TTLL3: NX_Q9Y4R7

TTLL3 Protein expression data from MOPED and PaxDb: --

REFSEQ proteins: NP_001021100.3

ENSEMBL proteins:

ENSP00000399930 ENSP00000399782 ENSP00000401686 ENSP00000414965 ENSP00000408128

ENSP00000394481 ENSP00000400462 ENSP00000402197 ENSP00000395912 ENSP00000392549

ENSP00000389904 ENSP00000398996 ENSP00000412915 ENSP00000396606 ENSP00000312148

ENSP00000399191 ENSP00000398097 ENSP00000373338 ENSP00000430051 ENSP00000409632

ENSP00000409246 ENSP00000403874 ENSP00000446659 ENSP00000380416 ENSP00000394462

Human Recombinant Protein Products for TTLL3:

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	Novus Biologicals TTLL3 Protein Novus Biologicals TTLL3 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TTLL3

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	--	--
GO:0005874	microtubule	IEA	--
GO:0005929	cilium	ISS	--
GO:0015630	microtubule cytoskeleton	ISS	--
GO:0035085	cilium axoneme	ISS	--

TTLL3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for TTLL3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TTLL3 for domains About GeneDecksing

1 InterPro domain/family:

IPR004344 Tub_tyr_ligase

Graphical View of Domain Structure for InterPro Entry Q9Y4R7

ProtoNet protein and cluster: Q9Y4R7

1 Blocks protein family: IPB004344 Tubulin-tyrosine ligase

UniProtKB/Swiss-Prot: TTLL3_HUMAN, Q9Y4R7

Similarity: Contains 1 TTL domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: TTLL3_HUMAN, Q9Y4R7

Function: Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl

groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the

side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side

chains. Not involved in elongation step of the polyglycylation reaction

Enzyme Number (IUBMB): EC 6.3.2.-¹

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004835	tubulin-tyrosine ligase activity	IEA	--
GO:0005524	ATP binding	--	--
GO:0070735	protein-glycine ligase activity	IDA	19524510
GO:0070736	protein-glycine ligase activity, initiating	ISS	--

TTLL3 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TTLL3

miRNA Products:		OriGene 3'-UTR Clone: TTLL3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL3
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate TTLL3:
		hsa-miR-3607-3p hsa-miR-3154 hsa-miR-513a-5p
		SwitchGear 3'UTR luciferase reporter plasmid: TTLL3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTLL3 (see all 7) OriGene shRNA RFP: TTLL3 OriGene siRNA: TTLL3
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTLL3 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTLL3 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TTLL3 (NM_001025930)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TTLL3

3 Interacting proteins for TTLL3 (Q9Y4R7^{2, 3}) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ARPC5L	Q9BPX5²^,³	MINT-65307 I2D: score=1
NELFCD	Q8IXH7²^,³	MINT-64863 I2D: score=1
RNF130	Q86XS8²^,³	MINT-64838 I2D: score=1

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006464	cellular protein modification process	--	--
GO:0018094	protein polyglycylation	IDA	19524510
GO:0035082	axoneme assembly	ISS	--
GO:0042384	cilium assembly	ISS	--

TTLL3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TTLL3
Search CenterWatch for drugs/clinical trials and news about TTLL3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TTLL3 gene (2 alternative transcripts):

NM_015644.3 NM_001025930.3

Unigene Cluster for TTLL3:

Tubulin tyrosine ligase-like family, member 3

Hs.726435 [show with all ESTs]

Unigene Representative Sequence: NR_037162

18/35 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 35):

ENST00000414814 ENST00000452597 ENST00000419081 ENST00000438596 ENST00000459758

ENST00000417065 ENST00000439814 ENST00000418745 ENST00000430718 ENST00000427220(uc003btf.4)

ENST00000426895 ENST00000426827 ENST00000431204 ENST00000422738 ENST00000430390

ENST00000483051(uc003bth.4 uc011atj.2) ENST00000310252 ENST00000496526(uc010hco.1)

miRNA Products:		OriGene 3'-UTR Clone: TTLL3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL3
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate TTLL3:
		hsa-miR-3607-3p hsa-miR-3154 hsa-miR-513a-5p
		SwitchGear 3'UTR luciferase reporter plasmid: TTLL3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTLL3 (see all 7) OriGene shRNA RFP: TTLL3 OriGene siRNA: TTLL3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTLL3
		Sirion Biotech Custom design and validation of potent shRNA sequences against TTLL3

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		GenScript: all cDNA clones in your preferred vector: TTLL3 (NM_001025930)
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Additional cDNA sequence:

AF078842.1 AK023960.1 AK297289.1 AK315140.1 BC028169.1 BC113824.1 NR_037162.1

24/34 DOTS entries (see all 34):

DT.120858267 DT.97862294 DT.120858167 DT.100816487 DT.95198356 DT.91761091 DT.91807281 DT.99974535

DT.120858189 DT.92389612 DT.95209709 DT.97862293 DT.100816484 DT.120858275 DT.425915 DT.86790120

DT.95148959 DT.120858163 DT.120858268 DT.97783976 DT.97861105 DT.100736995 DT.120858175 DT.120858220

24/645 AceView cDNA sequences (see all 645):

CR609636 BM449575 BM845194 CA488436 BX357758 BM925196 BQ641790 CB135971

CR614179 BI768100 CA313820 CR617543 BE243485 BQ424109 BU541432 AI864496

BE859023 AW204341 AA996151 BM553110 CR608569 BQ069395 BX419672 BQ707699

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TTLL3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGAAACCGT

About this image

TTLL3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Somite

Lumbar Vertebral Body

Somite

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Genevestigator expression for TTLL3

SOURCE GeneReport for Unigene cluster: Hs.726435

SABiosciences Custom PCR Arrays for TTLL3

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TTLL3 gene from 3/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	TTLL3⁶	--	58(a)	1 → many	2(191298565-191314384)
zebrafish (Danio rerio)	Actinopterygii	ttll3¹	tubulin tyrosine ligase-like family, member 3	57.37(n) 51.44(a)		724000 NM_001045305.1 NP_001038770.1
fruit fly (Drosophila melanogaster)	Insecta	TTLL3A¹	Tubulin tyrosine ligase-like 3A	49.97(n) 39.23(a)		33947 NM_135225.1 NP_609069.1

ENSEMBL Gene Tree for TTLL3 (if available)
TreeFam Gene Tree for TTLL3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TTLL3 gene

TTLL10² TTLL4² TTLL1² TTLL5² TTLL11² TTLL9² TTLL7² TTLL6²

TTL² TTLL8² TTLL2² TTLL13² ARPC4-TTLL3²

2 SIMAP similar genes for TTLL3 using alignment to 20 protein entries: TTLL3_HUMAN (see all proteins):

ARPC4-TTLL3 TTLL8

TTLL3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs34481871^1,2	C	--	9809145(+)	`TTTTT-/TGTCTC`	1	--	int¹		1		NA	2
rs78093735^1,2	C	--	9849653(+)	`TGTGTA/GAAAGG`	3	--	us2k¹ int¹		3		CSA WA EA	239
rs183164026^1,2		--	9849658(+)	`AAAAGC/GTTCAC`	3	--	int¹ us2k¹		0	--	--	--	--
rs75905397^1,2		--	9849814(+)	`ATGGGG/TTGGAC`	3	--	int¹ us2k¹		0	--	--	--	--
rs149291569^1,2		--	9849862(+)	`TGGAAC/TAGCTA`	3	--	us2k¹ int¹		0	--	--	--	--
rs9879678^1,2	C	--	9849889(+)	`CCCCCT/CTTTTT`	3	--	us2k¹ int¹		4		WA NA CSA	7
rs61239646^1,2	C	--	9849890(+)	`CCCCCC/TTTTTT`	3	--	us2k¹ int¹		0	--	--	--	--
rs113807171^1,2	C	--	9849916(+)	`ACAGGA/G/TTCTCG`	3	--	int¹ us2k¹		1		WA	2
rs187023409^1,2		--	9849936(+)	`CCAGGC/GTGGAG`	3	--	us2k¹ int¹		0	--	--	--	--
rs191913344^1,2		--	9850058(+)	`GCTAAC/TTTTTT`	3	--	us2k¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TTLL3 (9849770 - 9896822 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TTLL3
1 CNV: 6156
1 Indel: 59154

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTLL3

DNA2.0 Custom Variant and Variant Library Synthesis for TTLL3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TTLL3 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with TTLL3)

Utopia: connect your pdf to the dynamic
world of online information

Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. (PubMed id 19524510)^{1, 2} Rogowski K....Janke C. (2009)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1. (PubMed id 11054573)^{1, 3} Trichet V.... De Sario A. (2000)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)² Sjoeblom T.... Velculescu V.E. (2006)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)¹ Suzuki Y.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 26140	HGNC: 24483	AceView: ARPC4andTTLL3	Ensembl:ENSG00000214021	euGenes: HUgn26140
ECgene: TTLL3	H-InvDB: TTLL3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TTLL3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TTLL3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TTLL3 gene:
Search GeneIP for patents involving TTLL3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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TTLL3 Gene

tubulin tyrosine ligase-like family, member 3

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TTLL3 Gene

tubulin tyrosine ligase-like family, member 3

Aliasesfor TTLL3 gene

Summariesfor TTLL3 gene

Genomic Viewsfor TTLL3 gene

Proteinsfor TTLL3 gene

Protein Domains /Familiesfor TTLL3 gene

Functionfor TTLL3 gene

Pathways & Interactionsfor TTLL3 gene

Drugs & Compoundsfor TTLL3 gene

Transcriptsfor TTLL3 gene

Expression for TTLL3 gene

Orthologsfor TTLL3 gene

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Genomic Variantsfor TTLL3 gene

Disorders / Diseasesfor TTLL3 gene

Publicationsfor TTLL3 gene

External Searches for TTLL3 gene

Genome Databases showing TTLL3 gene

Other Databases showing TTLL3 gene

Specialized Databases showing TTLL3 gene

Intellectual Propertyfor TTLL3 gene

Productsfor TTLL3 gene

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Aliases
for TTLL3 gene

Summaries
for TTLL3 gene

Genomic Views
for TTLL3 gene

Proteins
for TTLL3 gene

Protein Domains /
Families
for TTLL3 gene

Function
for TTLL3 gene

Pathways & Interactions
for TTLL3 gene

Drugs & Compounds
for TTLL3 gene

Transcripts
for TTLL3 gene

Expression
for TTLL3 gene

Orthologs
for TTLL3 gene

Paralogs
for TTLL3 gene

Genomic Variants
for TTLL3 gene

Disorders / Diseases
for TTLL3 gene

Publications
for TTLL3 gene

Intellectual Property
for TTLL3 gene

Products
for TTLL3 gene