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Aliases for TTLL13P Gene

Aliases for TTLL13P Gene

  • Tubulin Tyrosine Ligase-Like Family Member 13, Pseudogene 2 3
  • Tubulin Tyrosine Ligase-Like Family, Member 13 2 3
  • Tubulin--Tyrosine Ligase-Like Protein 13 3 4
  • TTLL13 3 4
  • Tubulin Tyrosine Ligase-Like Family Member 13 Pseudogene 4
  • Tubulin Polyglutamylase TTLL13 3
  • EC 6.-.-.- 4

External Ids for TTLL13P Gene

Previous HGNC Symbols for TTLL13P Gene

  • TTLL13

Summaries for TTLL13P Gene

GeneCards Summary for TTLL13P Gene

TTLL13P (Tubulin Tyrosine Ligase-Like Family Member 13, Pseudogene) is a Pseudogene. An important paralog of this gene is TTLL8.

UniProtKB/Swiss-Prot for TTLL13P Gene

  • Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTLL13P Gene

Genomics for TTLL13P Gene

Genomic Location for TTLL13P Gene

Start:
90,249,530 bp from pter
End:
90,265,482 bp from pter
Size:
15,953 bases
Orientation:
Plus strand

Genomic View for TTLL13P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTLL13P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTLL13P Gene

No data available for Regulatory Elements for TTLL13P Gene

Proteins for TTLL13P Gene

  • Protein details for TTLL13P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNM8-TTL13_HUMAN
    Recommended name:
    Tubulin polyglutamylase TTLL13P
    Protein Accession:
    A6NNM8
    Secondary Accessions:

    Protein attributes for TTLL13P Gene

    Size:
    815 amino acids
    Molecular mass:
    93645 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BC036668; Type=Frameshift; Positions=298; Evidence={ECO:0000305};

    Alternative splice isoforms for TTLL13P Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TTLL13P Gene

Proteomics data for TTLL13P Gene at MOPED

Post-translational modifications for TTLL13P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TTLL13P Gene

Domains for TTLL13P Gene

Gene Families for TTLL13P Gene

HGNC:
  • TTLL :Tubulin tyrosine ligase-like family

Protein Domains for TTLL13P Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A6NNM8

UniProtKB/Swiss-Prot:

TTL13_HUMAN :
  • A6NNM8
Domain:
  • Contains 1 TTL domain.
Family:
  • Belongs to the tubulin--tyrosine ligase family.
genes like me logo Genes that share domains with TTLL13P: view

No data available for Suggested Antigen Peptide Sequences for TTLL13P Gene

Function for TTLL13P Gene

Molecular function for TTLL13P Gene

UniProtKB/Swiss-Prot Function: Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity).

Enzyme Numbers (IUBMB) for TTLL13P Gene

Gene Ontology (GO) - Molecular Function for TTLL13P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016874 ligase activity IEA --
genes like me logo Genes that share ontologies with TTLL13P: view

Animal Model Products

miRNA for TTLL13P Gene

miRTarBase miRNAs that target TTLL13P

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTLL13P

In Situ Assay Products

Flow Cytometry Products

No data available for Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TTLL13P Gene

Localization for TTLL13P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TTLL13P Gene

Pathways for TTLL13P Gene

SuperPathways for TTLL13P Gene

No Data Available

Interacting Proteins for TTLL13P Gene

Gene Ontology (GO) - Biological Process for TTLL13P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006464 cellular protein modification process IEA --
genes like me logo Genes that share ontologies with TTLL13P: view

No data available for Pathways by source for TTLL13P Gene

Transcripts for TTLL13P Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTLL13P

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TTLL13P
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTLL13P Gene

No ASD Table

Relevant External Links for TTLL13P Gene

GeneLoc Exon Structure for
TTLL13P
ECgene alternative splicing isoforms for
TTLL13P

Expression for TTLL13P Gene

mRNA expression in normal human tissues for TTLL13P Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TTLL13P Gene

genes like me logo Genes that share expressions with TTLL13P: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TTLL13P Gene

Orthologs for TTLL13P Gene

This gene was present in the common ancestor of animals.

Orthologs for TTLL13P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 56 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 49 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Ttll13 16
Ttll13 36
  • 49 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 46 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 54 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 74 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 51 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG16716 36
  • 21 (a)
ManyToMany
CG5987 36
  • 29 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 66 (a)
OneToMany
Species with no ortholog for TTLL13P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TTLL13P Gene

ENSEMBL:
Gene Tree for TTLL13P (if available)
TreeFam:
Gene Tree for TTLL13P (if available)

Paralogs for TTLL13P Gene

genes like me logo Genes that share paralogs with TTLL13P: view

Variants for TTLL13P Gene

Relevant External Links for TTLL13P Gene

HapMap Linkage Disequilibrium report
TTLL13P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TTLL13P Gene

Disorders for TTLL13P Gene

No disorders were found for TTLL13P Gene.

No data available for UniProtKB/Swiss-Prot for TTLL13P Gene

Publications for TTLL13P Gene

  1. Tubulin polyglutamylase enzymes are members of the TTL domain protein family. (PMID: 15890843) Janke C. … Edde B. (Science 2005) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TTLL13P Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate TTLL13P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TTLL13P
    • Block miRNA regulation of TTLL13P using miScript Target Protectors

    Sources for TTLL13P Gene

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