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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TTLL11 Gene

protein-coding   GIFtS: 45
GCID: GC09M124584

Tubulin Tyrosine Ligase-Like Family, Member 11

(Previous name: chromosome 9 open reading frame 20)
(Previous symbol: C9orf20)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tubulin Tyrosine Ligase-Like Family, Member 111 2     bA244O19.12
C9orf201 2 3     Tubulin Polyglutamylase TTLL112
Tubulin--Tyrosine Ligase-Like Protein 112 3     EC 6.-.-.-3
Chromosome 9 Open Reading Frame 201     

External Ids:    HGNC: 181131   Entrez Gene: 1581352   Ensembl: ENSG000001757647   UniProtKB: Q8NHH13   

Export aliases for TTLL11 gene to outside databases

Previous GC identifers: GC09M121664 GC09M123624 GC09M123791 GC09M094322


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TTLL11 Gene: 
TTLL11 (tubulin tyrosine ligase-like family, member 11) is a protein-coding gene. Diseases associated with TTLL11 include cleft lip. GO annotations related to this gene include tubulin-tyrosine ligase activity. An important paralog of this gene is TTLL4.

UniProtKB/Swiss-Prot: TTL11_HUMAN, Q8NHH1
Function: Polyglutamase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of
the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP
localization to both spindle and cilia microtubules




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008470.19  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TTLL11 gene promoter:
         GR   Pbx1a   p53   Meis-1b   CP2   HOXA5   Meis-1a   GR-alpha   ATF6   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TTLL11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTLL11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q33.2   Ensembl cytogenetic band:  9q33.2   HGNC cytogenetic band: 9q34.11

TTLL11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTLL11 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M124584:  view genomic region     (about GC identifiers)

Start:
124,584,204 bp from pter      End:
124,855,885 bp from pter
Size:
271,682 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TTL11_HUMAN, Q8NHH1 (See protein sequence)
Recommended Name: Tubulin polyglutamylase TTLL11  
Size: 538 amino acids; 58035 Da
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body (By similarity)

Explore the universe of human proteins at neXtProt for TTLL11: NX_Q8NHH1

Explore proteomics data for TTLL11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NHH1

  • TTLL11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TTLL11 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001132914.1  NP_919228.2  

    ENSEMBL proteins: 
     ENSP00000362881   ENSP00000321346  

    Human Recombinant Protein Products for TTLL11: 
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    Cloud-Clone Corp. Proteins for TTLL11 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005929cilium IEA--
    GO:0005932microtubule basal body IEA--

    TTLL11 for ontologies           About GeneDecksing



    TTLL11 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for TTLL11


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TTLL: Tubulin tyrosine ligase-like family

    1 InterPro protein domain:
     IPR004344 Tub_tyr_ligase

    Graphical View of Domain Structure for InterPro Entry Q8NHH1

    ProtoNet protein and cluster: Q8NHH1

    1 Blocks protein domain: IPB004344 Tubulin-tyrosine ligase

    UniProtKB/Swiss-Prot: TTL11_HUMAN, Q8NHH1
    Similarity: Belongs to the tubulin--tyrosine ligase family
    Similarity: Contains 1 TTL domain


    TTLL11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TTL11_HUMAN, Q8NHH1
    Function: Polyglutamase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of
    the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP
    localization to both spindle and cilia microtubules

         Enzyme Number (IUBMB): EC 6.-.-.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004835tubulin-tyrosine ligase activity ----
    GO:0016874ligase activity IEA--
         
    TTLL11 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TTLL11:
     Cell cycle / mitosis defect 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TTLL11 
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTLL11 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTLL11
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TTLL11:
    hsa-miR-495 hsa-miR-7-1* hsa-miR-7-2*
    SwitchGear 3'UTR luciferase reporter plasmidTTLL11 3' UTR sequence
    Inhib. RNA
    Products:
        
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTLL11

    1 Interacting protein for TTLL11 (Q8NHH12) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    --P310162MINT-8108126
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006464cellular protein modification process IEA--
    GO:0018095protein polyglutamylation ----
    GO:0051013microtubule severing ----

    TTLL11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TTLL11 (TTL11)

    Search CenterWatch for drugs/clinical trials and news about TTLL11 / TTL11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TTLL11 gene (2 alternative transcripts): 
    NM_001139442.1  NM_194252.2  

    Unigene Cluster for TTLL11:

    Tubulin tyrosine ligase-like family, member 11
    Hs.640663  [show with all ESTs]
    Unigene Representative Sequence: NM_001139442
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486362 ENST00000373778 ENST00000474723 ENST00000487468 ENST00000373776(uc004blt.1 uc004blu.1)
    ENST00000321582(uc011lym.1 uc011lyl.2 uc004blr.3)
    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TTLL11:
    hsa-miR-495 hsa-miR-7-1* hsa-miR-7-2*
    SwitchGear 3'UTR luciferase reporter plasmidTTLL11 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTLL11
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTLL11

    Additional mRNA sequence: 

    AF521886.1 AF521887.1 BC089452.1 BC171751.1 

    4 DOTS entries:

    DT.99947626  DT.40265942  DT.208691  DT.99947228 

    24/36 AceView cDNA sequences (see all 36):

    CF128404 BM929722 AA609430 AI571330 AK125178 AF521886 AI741070 NM_194252 
    AI150621 AW629275 AF521887 BF108868 BF594279 AA861826 AA676222 AI472951 
    BF439913 BG771772 AI185724 BX282469 BX092305 AI769213 AW015518 BQ103840 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TTLL11    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                    -                             -     -     -                     
    SP2:                                                                                    
    SP3:                                                              -                     
    SP4:                                                                                    


    ECgene alternative splicing isoforms for TTLL11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TTLL11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TTLL11 Expression
    About this image


    See TTLL11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TTLL11

    SOURCE GeneReport for Unigene cluster: Hs.640663
        SABiosciences Custom PCR Arrays for TTLL11
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTLL11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TTLL11 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ttll111 , 5 tubulin tyrosine ligase-like family, member 111, 5 82.58(n)1
    80.79(a)1
      2 (23.90 cM)5
    744101  NM_028921.21  NP_083197.21 
     357512415 
    chicken
    (Gallus gallus)
    Aves TTLL111 tubulin tyrosine ligase-like family, member 11 75.53(n)
    79.97(a)
      417115  XM_415399.3  XP_415399.3 
    lizard
    (Anolis carolinensis)
    Reptilia TTLL116
    Uncharacterized protein
    69(a)
    1 ↔ 1
    AAWZ02037732(1273-13830)
    zebrafish
    (Danio rerio)
    Actinopterygii ttll111 tubulin tyrosine ligase-like family, member 11 65.66(n)
    70.69(a)
      558156  NM_001077375.1  NP_001070843.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ttll-111 Protein TTLL-11 47(n)
    39.2(a)
      177677  NM_171405.3  NP_741471.2 


    ENSEMBL Gene Tree for TTLL11 (if available)
    TreeFam Gene Tree for TTLL11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TTLL11 gene
    TTLL42  TTLL102  ENSG000002611472  TTLL32  TTLL12  TTLL52  TTLL92  TTLL72  
    TTLL62  TTL2  TTLL82  TTLL22  TTLL132  ARPC4-TTLL32  
    5 SIMAP similar genes for TTLL11 using alignment to 4 protein entries:     TTL11_HUMAN (see all proteins):
    TTLL6    TTLL13    TTLL7    TTLL5    TTLL4

    TTLL11 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3976 SNPs in TTLL11 are shown (see all 3976)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1168559821,2
    C,F--124583952(+) CCTGAC/ACCTGG 1 -- int11Minor allele frequency- A:0.02NA 120
    rs70238591,2
    C,F--124584261(+) ATTAAT/CTTTTT 1 -- ut311Minor allele frequency- C:0.03WA 118
    rs1507091541,2
    C--124584414(+) CGGAAC/TGGGCG 1 -- ut310--------
    rs78690451,2
    C,F--124584495(+) CACTCG/AGCTTC 1 -- ut31 ese36Minor allele frequency- A:0.12NA WA 246
    rs1391129861,2
    C--124584560(+) AGATTC/TGCCCC 1 -- ut310--------
    rs1885812911,2
    --124584809(+) TGGGGC/TGCTCC 1 -- ut310--------
    rs1928009461,2
    --124584833(+) GCTCTC/TGTCTT 1 -- ut310--------
    rs1825230011,2
    --124585093(+) AAGTGG/TCAGCA 2 T P mis10--------
    rs1440222961,2
    --124585202(+) TGCCCC/TACGCT 1 -- int10--------
    rs1459821831,2
    C--124585208(+) ACGCTA/GCCCTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for TTLL11 (124584204 - 124834204 bp, first 250kb of TTLL11)

    Structural Variations
         Database of Genomic Variants (DGV) 10/27 variations for TTLL11 (see all 27):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2739012CNV Deletion23290073
    esv2739007CNV Deletion23290073
    esv4168CNV Deletion18987735
    esv997735CNV Deletion20482838
    esv2739011CNV Deletion23290073
    esv2671139CNV Deletion23128226
    esv2675052CNV Deletion23128226
    esv2739009CNV Deletion23290073
    esv1964984CNV Deletion18987734
    esv3570CNV Deletion18987735


    Human Gene Mutation Database (HGMD): TTLL11
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TTLL11
    DNA2.0 Custom Variant and Variant Library Synthesis for TTLL11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TTLL11:    About MalaCards
    cleft lip    


    TTLL11 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TTLL11
    Human Genome Epidemiology (HuGE) Navigator: TTLL11 (2 documents)

    Export disorders for TTLL11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TTLL11 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with TTLL11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PubMed id 20583170)1, 4 Letra A....Vieira A.R. (2010)
    3. Tubulin polyglutamylase enzymes are members of the TTL domain protein family. (PubMed id 15890843)1, 3 Janke C.... Edde B. (2005)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. Genome-wide association study of periodontal pathogen colonization. (PubMed id 22699663)1 Divaris K....Offenbacher S. (2012)
    6. CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development. (PubMed id 22493317)2 Backer C.B.... Cheeseman I.M. (2012)
    7. The SH3 domain of postsynaptic density 95 mediates inf lammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (2010)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 158135 HGNC: 18113 AceView: C9orf20 Ensembl:ENSG00000175764 euGenes: HUgn158135
    ECgene: TTLL11 H-InvDB: TTLL11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TTLL11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TTLL11 gene:
    Search GeneIP for patents involving TTLL11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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