TTI1 Gene
protein-coding GIFtS: 48
GCID: GC20M036612
|
|
TELO2 interacting protein 1(Previous names: KIAA0406, Tel2 interacting protein 1 homolog (S. pombe)...)
(Previous symbol: KIAA0406)
| |
Aliases
for TTI1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| TELO2 Interacting Protein 11 2 | | Tel2 Interacting Protein 1 Homolog2 | | KIAA04061 2 3 | | TEL2-Interacting Protein 1 Homolog2 | | Smg-101 | | TELO2-Interacting Protein 1 Homolog2 | | Tel2 Interacting Protein 1 Homolog (S. Pombe)1 | | SMG103 | | Smg-10 Homolog, Nonsense Mediated MRNA Decay Factor2 | | Protein SMG103 | | Tel Two Interacting Protein 12 | | |
Export aliases for TTI1 gene to outside databasesPrevious GC identifer: GC20M033347 |
Summaries
for TTI1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: TTI1_HUMAN, O43156Function: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize proteinlevels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involvedin the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growthand survival in response to nutrient and hormonal signals
|
Genomic Views
for TTI1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TTI1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TTI1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTI1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q11.23 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q11.23TTI1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M036612: view genomic region
(about GC identifiers)
Start:
|
36,611,409 bp from pter |
End:
|
36,661,870 bp from pter |
Size:
|
50,462 bases |
Orientation:
|
minus strand |
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Proteins
for TTI1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TTI1_HUMAN, O43156 (See
protein sequence)Recommended Name: TELO2-interacting protein 1 homolog Size: 1089 amino acids; 122069 Da
Subunit: Component of the TTT complex composed of TELO2, TTI1 and TTI2. Interacts with ATM, ATR, MTOR, PRKDC, SMG1,TELO2, TRRAP AND TTI2. Component of the mTORC1 and mTORC2 complexes
Subcellular location: Cytoplasm
Sequence caution: Sequence=BAA23702.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q5JX67 Q96A38 Q9BR47 Q9H4K0Explore the universe of human proteins at neXtProt for TTI1: NX_O43156
Post-translational modifications:
Phosphorylated at Ser-828 by CK2 following growth factor deprivation, leading to its subsequent ubiquitination by theSCF(FBXO9) complex. Phosphorylation by CK2 only takes place when TELO2 is bound to mTORC1, not mTORC2; leading toselective ubiquitination of mTORC1-associated protein1
Ubiquitinated by the SCF(FBXO9) complex following phosphorylation by CK2 in response to growth factor deprivation,leading to its degradation by the proteasome. Only mTORC1-associated protein is ubiquitinated and degraded, leading toselective inactivation of mTORC1 to restrain cell growth and protein translation, while mTORC2 is activated due to therelief of feedback inhibition by mTORC11
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43156
TTI1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055472.1
ENSEMBL proteins: ENSP00000362547 ENSP00000362546 ENSP00000407270
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
TTI1 for ontologies About GeneDecksing
TTI1 Antibody Products:
Assay Products for TTI1: |
Protein
Domains /
Families
for TTI1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TTI1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43156ProtoNet protein and cluster: O43156 1 Blocks protein family: IPB000357 HEAT repeat
UniProtKB/Swiss-Prot: TTI1_HUMAN, O43156Similarity: Belongs to the tti1 family |
Function
for TTI1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TTI1_HUMAN, O43156Function: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize proteinlevels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involvedin the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growthand survival in response to nutrient and hormonal signals
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTI1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTI1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TTI1 (NM_014657) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TTI1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTI1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTI1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
TTI1 for ontologies About GeneDecksing
|
Pathways & Interactions
for TTI1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTI1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/19 Interacting proteins for TTI1 (O431561, 3 ENSP000003625464) via UniProtKB, MINT, STRING, and/or I2D (see all 19)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| TELO2 | Q9Y4R81, 3, ENSP000002623194 | EBI-1055680,EBI-1047721 I2D:
score=1 STRING: ENSP00000262319 | | ATM | Q133151, 3, ENSP000002786164 | EBI-1055680,EBI-1059333 I2D:
score=1 STRING: ENSP00000278616 | | ATR | Q135351, 3, ENSP000003437414 | EBI-1055680,EBI-968983 I2D:
score=1 STRING: ENSP00000343741 | | PRKDC | P785273, ENSP000003134204 | I2D:
score=1 STRING: ENSP00000313420 | | PTP4A3 | O753653, ENSP000003322744 | I2D:
score=1 STRING: ENSP00000332274 |
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0032006 | regulation of TOR signaling cascade |
IMP | -- |
TTI1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TTI1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TTI1
Search CenterWatch for drugs/clinical trials and news about TTI1
|
Transcripts
for TTI1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TTI1 gene: NM_014657.1 Unigene Cluster for TTI1: TELO2 interacting protein 1 Hs.655481 [show with all ESTs]Unigene Representative Sequence: BC0131215 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373448(uc002xhl.3) ENST00000373447(uc002xhm.3) ENST00000473288
ENST00000487362 ENST00000449821
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTI1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTI1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TTI1 (NM_014657) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TTI1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTI1 |
Additional cDNA sequence: AB007866.2 AK095451.1 AK308164.1 BC013121.1 BC013755.1 BC107778.1 BC131759.1 8 DOTS entries: DT.101961860 DT.100694288 DT.212821 DT.100027212 DT.91687949 DT.120818872 DT.100684749 DT.95217085 24/140 AceView cDNA sequences (see all 140): CR607862 BG774398 AX748262 NM_014657 AA346191 CR596340 CB164765 AA046746 BU539305 AL559273 BU172334 AU132144 BQ064449 BU684997 AA355808 BX279765 AW294732 BM464983 BE883532 BC013755 CB125949 BX482228 BU170769 BC013121
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TTI1 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TTI1
|
Expression
for TTI1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TTI1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACGTGATGG
About this image
See TTI1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TTI1
SOURCE GeneReport for Unigene cluster: Hs.655481
UniProtKB/Swiss-Prot: TTI1_HUMAN, O43156Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for TTI1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTI1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTI1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTI1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTI1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTI1 |
Orthologs
for TTI1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TTI1 gene from 7/21 species (see all 21) About this table
ENSEMBL Gene Tree for TTI1 (if available)
TreeFam Gene Tree for TTI1 (if available) |
Paralogs
for TTI1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TTI1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TTI1 (36611409 - 36661870 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TTI1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTI1 |
|
Disorders
/ Diseases
for TTI1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 TTI1 for disorders About MalaCards
TTI1 for disorders About GeneDecksing
OMIM gene information: 614425
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: TTI1 (1 document)
Export disorders for TTI1 gene to outside databases
|
Publications
for TTI1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TTI1 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with TTI1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Tti1 and Tel2 are critical factors in mammalian targe t of rapamycin complex assembly. (PubMed id 20427287)1, 2, 3 Kaizuka T....Mizushima N. (2010)
- AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activ ity and function in nonsense-mediated mRNA decay. (PubMed id 20371770)1, 2, 3 Izumi N....Ohno S. (2010)
- Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2, 3 Ishikawa K....Ohara O. (1997)
- Tel2 structure and function in the Hsp90-dependent ma turation of mTOR and ATR complexes. (PubMed id 20801936)1, 2 Takai H....Pavletich N.P. (2010)
- A genetic screen identifies the Triple T complex requ ired for DNA damage signaling and ATM and ATR stability. (PubMed id 20810650)1, 2 Hurov K.E....Elledge S.J. (2010)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- SCF(Fbxo9) and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma. (PubMed id 23263282)2 Fernandez-Saiz V....Bassermann F. (2013)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for TTI1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TTI1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TTI1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing TTI1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TTI1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TTI1 gene:
Search GeneIP for patents involving TTI1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TTI1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TTI1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTI1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTI1 | | | OriGene Protein Over-expression Lysate for TTI1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TTI1 | | OriGene 3'-UTR Clone for TTI1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTI1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTI1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TTI1 | | OriGene Custom Protein Services for TTI1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TTI1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTI1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTI1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTI1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTI1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTI1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TTI1 |
| |  |  |  |  | | | | |
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 |
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 | | | TTI1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTI1 |
|  |  |  | | | | ThermoFisher Antibodies for TTI1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTI1 |
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