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Aliases for TTC9C Gene

Aliases for TTC9C Gene

  • Tetratricopeptide Repeat Domain 9C 2 3
  • TPR Repeat Protein 9C 4

External Ids for TTC9C Gene

Previous GeneCards Identifiers for TTC9C Gene

  • GC11P062254
  • GC11P062495
  • GC11P058825

Summaries for TTC9C Gene

GeneCards Summary for TTC9C Gene

TTC9C (Tetratricopeptide Repeat Domain 9C) is a Protein Coding gene. An important paralog of this gene is TTC9B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC9C Gene

Genomics for TTC9C Gene

Regulatory Elements for TTC9C Gene

Genomic Location for TTC9C Gene

62,728,069 bp from pter
62,740,293 bp from pter
12,225 bases
Plus strand

Genomic View for TTC9C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC9C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC9C Gene

Proteins for TTC9C Gene

  • Protein details for TTC9C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tetratricopeptide repeat protein 9C
    Protein Accession:
    Secondary Accessions:
    • Q8WYY7

    Protein attributes for TTC9C Gene

    171 amino acids
    Molecular mass:
    20013 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TTC9C Gene


neXtProt entry for TTC9C Gene

Proteomics data for TTC9C Gene at MOPED

Post-translational modifications for TTC9C Gene

  • Ubiquitination at Lys12
  • Modification sites at PhosphoSitePlus

Other Protein References for TTC9C Gene

No data available for DME Specific Peptides for TTC9C Gene

Domains for TTC9C Gene

Gene Families for TTC9C Gene

  • TTC :Tetratricopeptide (TTC) repeat domain containing

Protein Domains for TTC9C Gene

Suggested Antigen Peptide Sequences for TTC9C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8N5M4
  • Belongs to the TTC9 family.
  • Contains 3 TPR repeats.
genes like me logo Genes that share domains with TTC9C: view

Function for TTC9C Gene

Gene Ontology (GO) - Molecular Function for TTC9C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TTC9C: view

Phenotypes for TTC9C Gene

genes like me logo Genes that share phenotypes with TTC9C: view

Animal Model Products

CRISPR Products

miRNA for TTC9C Gene

miRTarBase miRNAs that target TTC9C

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC9C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TTC9C Gene

Localization for TTC9C Gene

Subcellular locations from

Jensen Localization Image for TTC9C Gene COMPARTMENTS Subcellular localization image for TTC9C gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TTC9C Gene

Pathways for TTC9C Gene

SuperPathways for TTC9C Gene

No Data Available

Gene Ontology (GO) - Biological Process for TTC9C Gene


No data available for Pathways by source for TTC9C Gene

Transcripts for TTC9C Gene

Unigene Clusters for TTC9C Gene

Tetratricopeptide repeat domain 9C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC9C

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC9C Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP2: - -
SP3: -
SP4: - - - - - -
SP5: -

Relevant External Links for TTC9C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TTC9C Gene

mRNA expression in normal human tissues for TTC9C Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TTC9C Gene

SOURCE GeneReport for Unigene cluster for TTC9C Gene Hs.31704

genes like me logo Genes that share expressions with TTC9C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TTC9C Gene

Orthologs for TTC9C Gene

This gene was present in the common ancestor of chordates.

Orthologs for TTC9C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TTC9C 35
  • 99.42 (n)
  • 100 (a)
TTC9C 36
  • 100 (a)
(Bos Taurus)
Mammalia -- 36
  • 92 (a)
-- 36
  • 92 (a)
TTC9C 35
  • 90.64 (n)
  • 94.15 (a)
TTC9C 36
  • 94 (a)
(Canis familiaris)
Mammalia TTC9C 35
  • 89.86 (n)
  • 94.74 (a)
TTC9C 36
  • 95 (a)
(Mus musculus)
Mammalia Ttc9c 35
  • 88.3 (n)
  • 95.91 (a)
Ttc9c 16
Ttc9c 36
  • 96 (a)
(Monodelphis domestica)
Mammalia TTC9C 36
  • 85 (a)
(Rattus norvegicus)
Mammalia Ttc9c 35
  • 89.28 (n)
  • 97.08 (a)
(Anolis carolinensis)
Reptilia TTC9C 36
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc9c 35
  • 57.12 (n)
  • 54.97 (a)
(Danio rerio)
Actinopterygii ttc9c 35
  • 58.43 (n)
  • 51.76 (a)
ttc9c 36
  • 40 (a)
Species with no ortholog for TTC9C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TTC9C Gene

Gene Tree for TTC9C (if available)
Gene Tree for TTC9C (if available)

Paralogs for TTC9C Gene

Paralogs for TTC9C Gene

Selected SIMAP similar genes for TTC9C Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with TTC9C: view

Variants for TTC9C Gene

Sequence variations from dbSNP and Humsavar for TTC9C Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2861 -- 62,738,525(-) AAGTA(A/G)TGAAG utr-variant-3-prime
rs6675 -- 62,738,292(-) ACGTT(A/C/G)GCATC reference, synonymous-codon
rs506088 -- 62,731,680(+) TTTTA(A/T)TTTTC intron-variant
rs514401 -- 62,733,032(-) CCTGT(A/G)CTGAT intron-variant
rs516168 -- 62,732,829(-) ttctc(C/T)tgcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TTC9C Gene

Variant ID Type Subtype PubMed ID
nsv897623 CNV Loss 21882294
nsv348 CNV Loss 18451855

Relevant External Links for TTC9C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTC9C Gene

Disorders for TTC9C Gene

No disorders were found for TTC9C Gene.

No data available for UniProtKB/Swiss-Prot for TTC9C Gene

Publications for TTC9C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. (PMID: 19165527) Martins-de-Souza D. … Turck C.W. (Eur Arch Psychiatry Clin Neurosci 2009) 3
  3. Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. (PMID: 19738201) Humphries J.D. … Humphries M.J. (Sci Signal 2009) 3
  4. A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. (PMID: 19875381) Gano J.J. … Simon J.A. (Mol. Cell. Proteomics 2010) 3
  5. Identification of FBXO25-interacting proteins using an integrated proteomics approach. (PMID: 20473970) Teixeira F.R. … Gomes M.D. (Proteomics 2010) 3

Products for TTC9C Gene

Sources for TTC9C Gene

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