Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TTC7B Gene

protein-coding   GIFtS: 43
GCID: GC14M091006

Tetratricopeptide Repeat Domain 7B

(Previous name: tetratricopeptide repeat domain 7 like 1)
(Previous symbol: TTC7L1)
  Search for TTC7B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tetratricopeptide Repeat Domain 7B1 2     TPR Repeat Protein 7-Like-12 3
TTC7L11 2 3     TPR Repeat Protein 7B2 3
Tetratricopeptide Repeat Domain 7 Like 11 2     c14_56852
Tetratricopeptide Repeat Protein 7-Like-12 3     Tetratricopeptide Repeat Protein 7B2

External Ids:    HGNC: 198581   Entrez Gene: 1455672   Ensembl: ENSG000001659147   UniProtKB: Q86TV63   

Export aliases for TTC7B gene to outside databases

Previous GC identifers: GC14M088997 GC14M090076 GC14M071182


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TTC7B Gene: 
TTC7B (tetratricopeptide repeat domain 7B) is a protein-coding gene. An important paralog of this gene is TTC7A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TTC7B gene promoter:
         TBP   Bach1   USF1   TFIID   FOXD3   MyoD   USF-1:USF-2   Cdc5   LCR-F1   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTTC7B promoter sequence
   Search SABiosciences Chromatin IP Primers for TTC7B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTC7B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.11   Ensembl cytogenetic band:  14q32.11   HGNC cytogenetic band: 14q32.12

TTC7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTC7B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M091006:  view genomic region     (about GC identifiers)

Start:
91,006,932 bp from pter      End:
91,282,823 bp from pter
Size:
275,892 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TTC7B_HUMAN, Q86TV6 (See protein sequence)
Recommended Name: Tetratricopeptide repeat protein 7B  
Size: 843 amino acids; 94179 Da
Sequence caution: Sequence=CAI46128.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAI46128.1; Type=Frameshift; Positions=718;
Secondary accessions: Q86U24 Q86VT3
Alternative splicing: 2 isoforms:  Q86TV6-1   Q86TV6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TTC7B: NX_Q86TV6

Explore proteomics data for TTC7B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86TV6

  • TTC7B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TTC7B Protein Expression
    REFSEQ proteins: NP_001010854.1  
    ENSEMBL proteins: 
     ENSP00000451825   ENSP00000336127   ENSP00000451440   ENSP00000452594   ENSP00000452031  
     ENSP00000450520   ENSP00000451928   ENSP00000451238   ENSP00000451201   ENSP00000349564  

    Human Recombinant Protein Products for TTC7B: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TTC7B
    GenScript Custom Purified and Recombinant Proteins Services for TTC7B
    Novus Biologicals TTC7B Protein
    Novus Biologicals TTC7B Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TTC7B 


    TTC7B Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TTC7B
    GenScript Custom Superior Antibodies Services for TTC7B
    Novus Biologicals TTC7B Antibody
    Abcam antibodies for TTC7B
    Cloud-Clone Corp. Antibodies for TTC7B 
    Search ThermoFisher Antibodies for TTC7B
    Search LSBio for Antibodies for TTC7B 

    Assay Products for TTC7B: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TTC7B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TTC7B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TTC7B 
    Cloud-Clone Corp. CLIAs for TTC7B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TTC: Tetratricopeptide (TTC) repeat domain containing

    5 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR013105 TPR_2
     IPR026900 Ttc7
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q86TV6

    ProtoNet protein and cluster: Q86TV6

    UniProtKB/Swiss-Prot: TTC7B_HUMAN, Q86TV6
    Similarity: Contains 11 TPR repeats


    TTC7B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    TTC7B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TTC7B:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TTC7B 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TTC7B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TTC7B 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTC7B 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTC7B
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate TTC7B (see all 13):
    hsa-miR-206 hsa-miR-130a* hsa-miR-183 hsa-miR-1 hsa-miR-23c hsa-miR-146a* hsa-miR-23b hsa-miR-493*
    SwitchGear 3'UTR luciferase reporter plasmidTTC7B 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TTC7B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTC7B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TTC7B
    Sirion Biotech Customized adenovirus for overexpression of TTC7B

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TTC7B (see all 5)
    OriGene ORF clones in mouse, rat for TTC7B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TTC7B (NM_001010854)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC7B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7B
    Sirion Biotech Customized lentivirus for stable overexpression of TTC7B 
                         Customized lentivirus expression plasmids for stable overexpression of TTC7B 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TTC7B
    Search LifeMap BioReagents cell lines for TTC7B
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTC7B

    4 Interacting proteins for TTC7B (Q86TV63) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GLI2P100703I2D: score=2 
    HGSO149643I2D: score=2 
    SRP68Q9UHB93I2D: score=1 
    UVRAGQ9P2Y53I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TTC7B

    Search CenterWatch for drugs/clinical trials and news about TTC7B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TTC7B gene: 
    NM_001010854.1  

    Unigene Cluster for TTC7B:

    Tetratricopeptide repeat domain 7B
    Hs.655697  [show with all ESTs]
    Unigene Representative Sequence: NM_001010854
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000555005(uc010ats.3) ENST00000328459(uc001xyp.3) ENST00000553972
    ENST00000554654 ENST00000555894 ENST00000557292 ENST00000556960 ENST00000557059
    ENST00000555239 ENST00000556490 ENST00000556749 ENST00000554462 ENST00000557766
    ENST00000553948 ENST00000557187 ENST00000357056(uc001xyo.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTC7B
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate TTC7B (see all 13):
    hsa-miR-206 hsa-miR-130a* hsa-miR-183 hsa-miR-1 hsa-miR-23c hsa-miR-146a* hsa-miR-23b hsa-miR-493*
    SwitchGear 3'UTR luciferase reporter plasmidTTC7B 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TTC7B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTC7B
    Clone
    Products:
         
    OriGene clones in human, mouse for TTC7B (see all 5)
    OriGene ORF clones in mouse, rat for TTC7B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TTC7B (NM_001010854)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC7B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7B
    Sirion Biotech Customized lentivirus for stable overexpression of TTC7B 
                         Customized lentivirus expression plasmids for stable overexpression of TTC7B 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TTC7B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTC7B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC7B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC7B

    Additional mRNA sequence: 

    AK126571.1 AL832848.1 BC048270.2 BX247966.1 BX248275.1 

    8 DOTS entries:

    DT.101982255  DT.455650  DT.100804970  DT.100784649  DT.100728936  DT.120753851  DT.40254590  DT.95157652 

    24/146 AceView cDNA sequences (see all 146):

    AI022911 AW572451 BU628337 H88622 C00831 AA128356 AI198357 BM127247 
    CR624723 AL707304 AW079694 BC035865 BX388694 BM718654 BU623692 CA430758 
    BF436104 AW207629 BF594721 CR602568 BX248275 AW130805 BE503574 BU783916 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TTC7B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b · 15c
    SP1:                                                                                -                                       
    SP2:                                                                          -     -                                       
    SP3:                                                                          -     -           -     -                     
    SP4:                                                                                                                        


    ECgene alternative splicing isoforms for TTC7B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TTC7B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAGATGAT
    TTC7B Expression
    About this image


    See TTC7B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TTC7B

    SOURCE GeneReport for Unigene cluster: Hs.655697
        SABiosciences Custom PCR Arrays for TTC7B
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TTC7B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTC7B
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC7B
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC7B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TTC7B gene from 8/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ttc7b1 , 5 tetratricopeptide repeat domain 7B1, 5 90.19(n)1
    97.15(a)1
      12 (50.43 cM)5
    1047181  NM_001033213.11  NP_001028385.11 
     1003007715 
    chicken
    (Gallus gallus)
    Aves TTC7B1 tetratricopeptide repeat domain 7B 80.98(n)
    93.7(a)
      423407  NM_001006484.1  NP_001006484.1 
    lizard
    (Anolis carolinensis)
    Reptilia TTC7B6
    Uncharacterized protein
    91(a)
    1 ↔ 1
    1(12278404-12398464)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.39212 Xenopus laevis transcribed sequence with weak similarity to protein spQ9ULT0 (H.sapiens) YB40_HUMAN Hypothetical protein KIAA1140 less 76.12(n)    BU914718.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570931222   -- 76.03(n)    57093122 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)k147101 lethal (2) k14710 47.62(n)
    37.61(a)
      48387  NM_143806.3  NP_652063.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y39A3CR.31 Protein Y39A3CR.3 41.74(n)
    29.64(a)
      175332  NM_065067.4  NP_497468.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NPGR11 no pollen germination related 1 protein 41.24(n)
    28.5(a)
      839637  NM_102510.1  NP_564285.1 


    ENSEMBL Gene Tree for TTC7B (if available)
    TreeFam Gene Tree for TTC7B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TTC7B gene
    TTC7A2  
    1 SIMAP similar gene for TTC7B using alignment to 8 protein entries:     TTC7B_HUMAN (see all proteins):
    TTC7A

    TTC7B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TTC7B
    PGOHUM00000247849


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5735 SNPs in TTC7B are shown (see all 5735)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1178618291,2
    C,F--91006452(+) AAACAC/TGTCCC 1 -- int11Minor allele frequency- T:0.03NA 120
    rs785427561,2
    C,F--91006453(+) AACACG/ATCCCT 1 -- int13Minor allele frequency- A:0.09WA NA EA 358
    rs1509159661,2
    --91006568(+) TTCAGA/GACCAG 1 -- int10--------
    rs1397567481,2
    --91006751(+) TGGGAA/CACAGA 1 -- int10--------
    rs1423823851,2
    --91006958(+) TATTAA/TCATCA 1 -- ut310--------
    rs1922717111,2
    --91007175(+) AGGACA/GGTAAT 1 -- ut310--------
    rs1847039681,2
    --91007485(+) GAACAA/CTGTCA 1 -- ut310--------
    rs1999943851,2
    C--91007519(+) CTGGC-/AAAAAA 1 -- ut310--------
    rs1890764071,2
    --91007582(+) GTTCAC/TTGTGG 1 -- ut310--------
    rs12945721,2
    C,F,O,H--91007618(+) CAGTGC/TGGCAG 1 -- ut31 ese317Minor allele frequency- T:0.02NA WA CSA EA 525

    HapMap Linkage Disequilibrium report for TTC7B (91006932 - 91256932 bp, first 250kb of TTC7B)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for TTC7B (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2659108CNV Deletion23128226
    esv2749010CNV Deletion23290073
    esv2660016CNV Deletion23128226
    esv2657236CNV Deletion23128226
    esv270875CNV Insertion20981092
    esv1610604CNV Insertion17803354
    esv272559CNV Insertion20981092
    esv1131124CNV Insertion17803354
    nsv84673CNV Loss16902084
    nsv832855CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TTC7B
    DNA2.0 Custom Variant and Variant Library Synthesis for TTC7B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TTC7B for disorders           About MalaCards

    TTC7B for disorders           About GeneDecksing

    Genetic Association Database (GAD): TTC7B

    Export disorders for TTC7B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TTC7B gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with TTC7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study does not reveal major ge netic determinants for anti-cytomegalovirus antibody response. (PubMed id 21993531)1, 4 Kuparinen T....Hurme M. (2012)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
    4. TTC7B emerges as a novel risk factor for ischemic stro ke through the convergence of several genome-wide approaches. (PubMed id 22453632)1 Krug T....Oliveira S.A. (2012)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 145567 HGNC: 19858 AceView: TTC7B Ensembl:ENSG00000165914 euGenes: HUgn145567
    ECgene: TTC7B H-InvDB: TTC7B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TTC7B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TTC7B gene:
    Search GeneIP for patents involving TTC7B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TTC7B  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TTC7B  
     OriGene qSTAR qPCR primer pairs in human, mouse for TTC7B   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TTC7B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TTC7B   OriGene Custom Protein Services for TTC7B  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TTC7B
     QIAGEN SeqTarget long-range PCR primers for resequencing TTC7B
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTC7B
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTC7B
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC7B
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC7B
     GenScript Custom Purified and Recombinant Proteins Services for TTC7B GenScript cDNA clones with any tag delivered in your preferred vector for TTC7B
     GenScript Custom Assay Services for TTC7B GenScript Custom Superior Antibodies Services for TTC7B
     GenScript Custom overexpressing Cell Line Services for TTC7B CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TTC7B promoter
     Search Chromatin IP Primers for TTC7B
     RT2 qPCR Primer Assay in human, mouse, rat TTC7B
     Search GNC Networks for TTC7B
     SABiosciences Custom PCR Arrays for TTC7B
     Search Tocris compounds for TTC7B
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TTC7B antibodies
     TTC7B proteins
     TTC7B lysates
     Antibodies for TTC7B
     See all of Abcam's Antibodies, Kits and Proteins for TTC7B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for TTC7B
     Antibodies for TTC7B
     ELISAs for TTC7B
     CLIAs for TTC7B
     Search LifeMap BioReagents cell lines for TTC7B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7B
     SwitchGear 3'UTR luciferase reporter plasmids for TTC7B
     SwitchGear Promoter luciferase reporter plasmids for TTC7B
     Search ThermoFisher Antibodies for TTC7B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7B
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TTC7B
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TTC7B
    Customized:
     lentivirus for stable overexpression of TTC7B
     lentivirus expression plasmids for stable overexpression of TTC7B
     adenovirus for overexpression of TTC7B
     Search LSBio for Antibodies for TTC7B
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TTC7B gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4