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TTC7B Gene

protein-coding   GIFtS: 46
GCID: GC14M091006

Tetratricopeptide Repeat Domain 7B

(Previous name: tetratricopeptide repeat domain 7 like 1)
(Previous symbol: TTC7L1)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tetratricopeptide Repeat Domain 7B1 2     TPR Repeat Protein 7-Like-12 3
TTC7L11 2 3     TPR Repeat Protein 7B2 3
Tetratricopeptide Repeat Domain 7 Like 11 2     c14_56852
Tetratricopeptide Repeat Protein 7-Like-12 3     Tetratricopeptide Repeat Protein 7B2

External Ids:    HGNC: 198581   Entrez Gene: 1455672   Ensembl: ENSG000001659147   UniProtKB: Q86TV63   

Export aliases for TTC7B gene to outside databases

Previous GC identifers: GC14M088997 GC14M090076 GC14M071182


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TTC7B Gene:
TTC7B (tetratricopeptide repeat domain 7B) is a protein-coding gene. Diseases associated with TTC7B include malaria. An important paralog of this gene is TTC7A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TTC7B gene promoter:
         TBP   Bach1   USF1   TFIID   FOXD3   MyoD   USF-1:USF-2   Cdc5   LCR-F1   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTTC7B promoter sequence
   Search Chromatin IP Primers for TTC7B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TTC7B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.11   Ensembl cytogenetic band:  14q32.11   HGNC cytogenetic band: 14q32.12

TTC7B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTC7B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M091006:  view genomic region     (about GC identifiers)

Start:
91,006,932 bp from pter      End:
91,282,823 bp from pter
Size:
275,892 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TTC7B_HUMAN, Q86TV6 (See protein sequence)
Recommended Name: Tetratricopeptide repeat protein 7B  
Size: 843 amino acids; 94179 Da
Sequence caution: Sequence=CAI46128.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAI46128.1; Type=Frameshift; Positions=718;
Secondary accessions: Q86U24 Q86VT3
Alternative splicing: 2 isoforms:  Q86TV6-1   Q86TV6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TTC7B: NX_Q86TV6

Explore proteomics data for TTC7B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TTC7B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001010854.1  
    ENSEMBL proteins: 
     ENSP00000451825   ENSP00000336127   ENSP00000451440   ENSP00000452594   ENSP00000452031  
     ENSP00000450520   ENSP00000451928   ENSP00000451238   ENSP00000451201   ENSP00000349564  

    TTC7B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TTC7B

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    Abcam antibodies for TTC7B
    Cloud-Clone Corp. Antibodies for TTC7B
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    Search LSBio for Antibodies for TTC7B

    TTC7B Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. CLIAs for TTC7B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TTC: Tetratricopeptide (TTC) repeat domain containing

    5 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR013105 TPR_2
     IPR026900 Ttc7
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q86TV6

    ProtoNet protein and cluster: Q86TV6

    UniProtKB/Swiss-Prot: TTC7B_HUMAN, Q86TV6
    Similarity: Contains 11 TPR repeats


    TTC7B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    TTC7B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TTC7B:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TTC7B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TTC7B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTC7B

    miRNA
    Products:
        
    miRTarBase miRNAs that target TTC7B:
    hsa-mir-375 (MIRT020039), hsa-mir-92a-3p (MIRT049562), hsa-mir-9-5p (MIRT021405)

    Block miRNA regulation of human, mouse, rat TTC7B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TTC7B (see all 13):
    hsa-miR-206 hsa-miR-130a* hsa-miR-183 hsa-miR-1 hsa-miR-23c hsa-miR-146a* hsa-miR-23b hsa-miR-493*
    SwitchGear 3'UTR luciferase reporter plasmidTTC7B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TTC7B
    Predesigned siRNA for gene silencing in human, mouse, rat TTC7B

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for TTC7B (see all 6)
    OriGene ORF clones in mouse, rat for TTC7B
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    GenScript: all cDNA clones in your preferred vector: TTC7B (NM_001010854)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7B

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TTC7B
    Interactions:

        Search GeneGlobe Interaction Network for TTC7B

    4 Interacting proteins for TTC7B (Q86TV63) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GLI2P100703I2D: score=2 
    HGSO149643I2D: score=2 
    SRP68Q9UHB93I2D: score=1 
    UVRAGQ9P2Y53I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TTC7B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TTC7B gene: 
    NM_001010854.1  

    Unigene Cluster for TTC7B:

    Tetratricopeptide repeat domain 7B
    Hs.655697  [show with all ESTs]
    Unigene Representative Sequence: NM_001010854
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000555005(uc010ats.3) ENST00000328459(uc001xyp.3) ENST00000553972
    ENST00000554654 ENST00000555894 ENST00000557292 ENST00000556960 ENST00000557059
    ENST00000555239 ENST00000556490 ENST00000556749 ENST00000554462 ENST00000557766
    ENST00000553948 ENST00000557187 ENST00000357056(uc001xyo.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TTC7B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TTC7B (see all 13):
    hsa-miR-206 hsa-miR-130a* hsa-miR-183 hsa-miR-1 hsa-miR-23c hsa-miR-146a* hsa-miR-23b hsa-miR-493*
    SwitchGear 3'UTR luciferase reporter plasmidTTC7B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TTC7B
    Predesigned siRNA for gene silencing in human, mouse, rat TTC7B
    Clone
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    OriGene clones in human, mouse for TTC7B (see all 6)
    OriGene ORF clones in mouse, rat for TTC7B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TTC7B (NM_001010854)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC7B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7B
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TTC7B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TTC7B
      QuantiTect SYBR Green Assays in human, mouse, rat TTC7B
      QuantiFast Probe-based Assays in human, mouse, rat TTC7B

    Additional mRNA sequence: 

    AK126571.1 AL832848.1 BC048270.2 BX247966.1 BX248275.1 

    8 DOTS entries:

    DT.101982255  DT.455650  DT.100804970  DT.100784649  DT.100728936  DT.120753851  DT.40254590  DT.95157652 

    Selected AceView cDNA sequences (see all 146):

    AW130805 BE503574 BU783916 AI587596 BX247966 BU158411 AW206083 BI964078 
    CR624723 AL707304 AW079694 BC035865 BX388694 BM718654 BU623692 BU628337 
    BF436104 CA430758 AI022911 AW572451 H88622 C00831 AA128356 AI198357 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TTC7B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b · 15c
    SP1:                                                                                -                                       
    SP2:                                                                          -     -                                       
    SP3:                                                                          -     -           -     -                     
    SP4:                                                                                                                        


    ECgene alternative splicing isoforms for TTC7B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TTC7B expression in normal human tissues (normalized intensities)      TTC7B embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAGATGAT
    TTC7B Expression
    About this image


    TTC7B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    TTC7B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TTC7B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655697
        Custom PCR Arrays for TTC7B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TTC7B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ttc7b1 , 5 tetratricopeptide repeat domain 7B1, 5 90.19(n)1
    97.15(a)1
      12 (50.43 cM)5
    1047181  NM_001033213.11  NP_001028385.11 
     1003007715 
    chicken
    (Gallus gallus)
    Aves TTC7B1 tetratricopeptide repeat domain 7B 80.98(n)
    93.7(a)
      423407  NM_001006484.1  NP_001006484.1 
    lizard
    (Anolis carolinensis)
    Reptilia TTC7B6
    tetratricopeptide repeat domain 7B
    91(a)
    1 ↔ 1
    1(12278404-12398464)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.39212 Xenopus laevis transcribed sequence with weak similarity more 76.12(n)    BU914718.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570931222   -- 76.03(n)    57093122 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)k147101 lethal (2) k14710 47.57(n)
    37.38(a)
      48387  NM_143806.4  NP_652063.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y39A3CR.31 Y39A3CR.3 42.78(n)
    31.04(a)
      175332  NM_001267916.1  NP_001254845.1 


    ENSEMBL Gene Tree for TTC7B (if available)
    TreeFam Gene Tree for TTC7B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TTC7B gene
    TTC7A2  
    1 SIMAP similar gene for TTC7B using alignment to 8 protein entries:     TTC7B_HUMAN (see all proteins):
    TTC7A

    TTC7B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TTC7B
    PGOHUM00000247849


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TTC7B (see all 5735)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1178618291,2
    C,F--91006452(+) AAACAC/TGTCCC 1 -- int11Minor allele frequency- T:0.03NA 120
    rs785427561,2
    C,F--91006453(+) AACACG/ATCCCT 1 -- int13Minor allele frequency- A:0.09WA NA EA 358
    rs1509159661,2
    --91006568(+) TTCAGA/GACCAG 1 -- int10--------
    rs1397567481,2
    --91006751(+) TGGGAA/CACAGA 1 -- int10--------
    rs1423823851,2
    --91006958(+) TATTAA/TCATCA 1 -- ut310--------
    rs1922717111,2
    --91007175(+) AGGACA/GGTAAT 1 -- ut310--------
    rs1847039681,2
    --91007485(+) GAACAA/CTGTCA 1 -- ut310--------
    rs1999943851,2
    C--91007519(+) CTGGC-/AAAAAA 1 -- ut310--------
    rs1890764071,2
    --91007582(+) GTTCAC/TTGTGG 1 -- ut310--------
    rs12945721,2
    C,F,O,H--91007618(+) CAGTGC/TGGCAG 1 -- ut31 ese317Minor allele frequency- T:0.02NA WA CSA EA 525

    HapMap Linkage Disequilibrium report for TTC7B (91006932 - 91256932 bp, first 250kb of TTC7B)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TTC7B (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2659108CNV Deletion23128226
    esv2749010CNV Deletion23290073
    esv2660016CNV Deletion23128226
    esv2657236CNV Deletion23128226
    esv270875CNV Insertion20981092
    esv1610604CNV Insertion17803354
    esv272559CNV Insertion20981092
    esv1131124CNV Insertion17803354
    nsv84673CNV Loss16902084
    nsv832855CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TTC7B
    DNA2.0 Custom Variant and Variant Library Synthesis for TTC7B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for TTC7B:    About MalaCards
    malaria


    TTC7B for disorders           About GeneDecksing

    Genetic Association Database (GAD): TTC7B

    Export disorders for TTC7B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TTC7B gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with TTC7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response. (PubMed id 21993531)1, 4 Kuparinen T....Hurme M. (Genes Immun. 2012)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (Nature 2003)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. TTC7B emerges as a novel risk factor for ischemic stroke through the convergence of several genome-wide approaches. (PubMed id 22453632)1 Krug T....Oliveira S.A. (J. Cereb. Blood Flow Metab. 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    8. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 145567 HGNC: 19858 AceView: TTC7B Ensembl:ENSG00000165914 euGenes: HUgn145567
    ECgene: TTC7B H-InvDB: TTC7B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TTC7B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for TTC7B gene:
    Search GeneIP for patents involving TTC7B

    GeneCards and IP:
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