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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TTC7A Gene

protein-coding GIFtS: 48
GCID: GC02P047143

tetratricopeptide repeat domain 7A

(Previous name: tetratricopeptide repeat domain 7 )
(Previous symbol: TTC7)

Explore 5 diseases affiliated with
TTC7A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tetratricopeptide Repeat Domain 7A¹ ²
TTC7¹ ² ³ ⁵
KIAA1140¹ ³ ⁵
TPR Repeat Protein 7A² ³
Tetratricopeptide Repeat Domain 7¹
Tetratricopeptide Repeat Protein 7A²

External Ids:	HGNC: 19750¹	Entrez Gene: 57217²	Ensembl: ENSG00000068724⁷	OMIM: 609332⁵	UniProtKB: Q9ULT0³

Export aliases for TTC7A gene to outside databases

Previous GC identifers: GC02P047079 GC02P047021 GC02P046906

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TTC7A:

The tetratricopeptide repeat (TPR) domain is defined by a degenerate consensus sequence of 34 amino acids. TPR

domain-containing proteins, such as TTC7A, have diverse functions in cell cycle control, protein transport, phosphate

turnover, and protein trafficking or secretion, and they can act as chaperones or scaffolding proteins (White et al.,

2005 (PubMed 15718100)).(supplied by OMIM, Mar 2008)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TTC7A gene promoter:
NF-1 NF-1/L AML1a GATA-3 Egr-1 Lmo2 Egr-4 CREB deltaCREB MRF-2
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for TTC7A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTC7A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2p16.3

TTC7A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTC7A gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P047143: view genomic region (about GC identifiers)

Start:	47,143,296 bp from pter	End:	47,303,276 bp from pter
Size:	159,981 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TTC7A_HUMAN, Q9ULT0 (See protein sequence)

Recommended Name: Tetratricopeptide repeat protein 7A

Size: 858 amino acids; 96185 Da

Sequence caution: Sequence=BAA86454.2; Type=Erroneous translation; Note=Wrong choice of CDS;

Secondary accessions: Q6PIX4 Q8ND67 Q9BUS3

Alternative splicing: 2 isoforms: Q9ULT0-1 Q9ULT0-3 (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for TTC7A: NX_Q9ULT0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9ULT0

TTC7A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065191.2

ENSEMBL proteins:

ENSP00000386307 ENSP00000316699 ENSP00000378320 ENSP00000393022 ENSP00000386521

ENSP00000401467 ENSP00000445265 ENSP00000263737

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TTC7A

TTC7A Antibody Products:

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	Novus Biologicals TTC7A Antibodies
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	Uscn Antibodies for TTC7A
	Search ThermoFisher Antibodies for TTC7A

Assay Products for TTC7A:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for TTC7A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for TTC7A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TTC7A for domains About GeneDecksing

5 InterPro domains/families:

IPR001440 TPR-1

IPR011990 TPR-like_helical

IPR026900 Ttc7

IPR013026 TPR-contain_dom

IPR019734 TPR_repeat

Graphical View of Domain Structure for InterPro Entry Q9ULT0

ProtoNet protein and cluster: Q9ULT0

UniProtKB/Swiss-Prot: TTC7A_HUMAN, Q9ULT0

Similarity: Contains 9 TPR repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		miRTarBase miRNAs that target TTC7A: hsa-mir-124 (MIRT002709)

		OriGene 3'-UTR Clone: TTC7A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTC7A
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate TTC7A (see all 21):
		hsa-miR-362-3p hsa-miR-125a-5p hsa-miR-331-3p hsa-miR-3692 hsa-miR-3171 hsa-miR-1184 hsa-miR-124 hsa-miR-125b

		SwitchGear 3'UTR luciferase reporter plasmid: TTC7A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTC7A (see all 7) OriGene shRNA RFP: TTC7A OriGene siRNA: TTC7A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTC7A

Gene Editing
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DNA2.0 Custom Protein Engineering Service for TTC7A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: TTC7A (NM_020458)
		Browse Sino Biological Human cDNA Clones
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TTC7A
		Search LifeMap BioReagents cell lines for TTC7A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7A

1 GenomeRNAi human phenotype for TTC7A:

Decreased nuclei size in G2M

Animal Models:
13 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Ttc7):

cardiovascular system	digestive/alimentary	growth/size	hematopoietic system	homeostasis/metabolism
immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging
pigmentation	renal/urinary system	tumorigenesis

TTC7A for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TTC7A

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for TTC7A (ENSP00000316699⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006879	cellular iron ion homeostasis	IEA	--
GO:0030097	hemopoiesis	IEA	--

TTC7A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TTC7A
Search CenterWatch for drugs/clinical trials and news about TTC7A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TTC7A gene:

NM_020458.2

Unigene Clusters for TTC7A:

Tetratricopeptide repeat domain 7A

Hs.370603 [show with all ESTs], Hs.736871 [show with all ESTs]

Unigene Representative Sequences: NM_020458, BC027457

14 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000409245 ENST00000319190(uc002rvn.1 uc002rvm.3 uc002rvo.3 uc010fbb.3 uc010fbc.3)

ENST00000461601 ENST00000394850 ENST00000441914 ENST00000409825(uc002rvp.3 uc002rvq.3 uc002rvr.3)

ENST00000474321 ENST00000491786 ENST00000484061 ENST00000440051 ENST00000484337

ENST00000496991 ENST00000536057 ENST00000263737

miRNA Products:		OriGene 3'-UTR Clone: TTC7A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TTC7A
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate TTC7A (see all 21):
		hsa-miR-362-3p hsa-miR-125a-5p hsa-miR-331-3p hsa-miR-3692 hsa-miR-3171 hsa-miR-1184 hsa-miR-124 hsa-miR-125b

		SwitchGear 3'UTR luciferase reporter plasmid: TTC7A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTC7A (see all 7) OriGene shRNA RFP: TTC7A OriGene siRNA: TTC7A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTC7A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTC7A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTC7A OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TTC7A (NM_020458)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC7A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC7A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTC7A Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC7A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC7A

Additional cDNA sequence:

AL117512.1 BC027457.2

18 DOTS entries:

DT.444751 DT.95256027 DT.100813457 DT.100641842 DT.95256014 DT.97808830 DT.95256011 DT.120932738

DT.95256008 DT.95256030 DT.91848849 DT.95256005 DT.95256026 DT.104046 DT.95256003 DT.95256013

DT.120932816 DT.97827439

3 AceView cDNA sequences:

AI418397 BF431723 BQ709930

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TTC7A (see all 7) About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7a	·	7b	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20	^	21	^	22	^
SP1:																	-						-																				-						-
SP2:							-						-				-						-																				-						-
SP3:																							-																				-						-
SP4:																																			-		-						-						-
SP5:																																																	-

ExUns:	23	^	24a	·	24b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for TTC7A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TTC7A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGGGACCT

About this image
See TTC7A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TTC7A

SOURCE GeneReport for Unigene clusters: Hs.370603 Hs.736871

SABiosciences Custom PCR Arrays for TTC7A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTC7A Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC7A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC7A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC7A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for TTC7A gene from 7/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	TTC7A¹	tetratricopeptide repeat domain 7A	69.67(n) 72.81(a)		421414 NM_001031055.1 NP_001026226.1
lizard (Anolis carolinensis)	Reptilia	-- --	--	73(a) 65(a)	1 ↔ many 1 ↔ many	2(143277551-143314871) 2(143136898-143186636)
zebrafish (Danio rerio)	Actinopterygii	ttc7a¹	tetratricopeptide repeat domain 7A	59.66(n) 54.57(a)		559345 XM_001921194.3 XP_001921229.3
fruit fly (Drosophila melanogaster)	Insecta	l(2)k14710⁶	lethal (2) k14710	32(a)	1 → many	2R(2097287-2101623)
worm (Caenorhabditis elegans)	Secernentea	Y39A3CR.3⁶	--	22(a)	1 → many	III(1860420-1877106)
thale cress (Arabidopsis thaliana)	eudicotyledons	NPG1¹	tetratricopeptide repeat-containing protein	41.01(n) 29.53(a)		818906 NM_180051.2 NP_850382.1
rice (Oryza sativa)	Liliopsida	Os11g0689300¹	hypothetical protein	39.26(n) 27.03(a)		4351154 NM_001075021.1 NP_001068489.1

ENSEMBL Gene Tree for TTC7A (if available)
TreeFam Gene Tree for TTC7A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TTC7A gene

TTC7B²

5 SIMAP similar genes for TTC7A using alignment to 9 protein entries: TTC7A_HUMAN (see all proteins):

L3MBTL2 TTC7B ADCY7 PAM16 PSEN1

TTC7A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs143089887^1,2		--	47166317(+)	`CAGGAC/GCTAAA`	8	--	us2k¹ int¹		0	--	--	--	--
rs192108801^1,2		--	47166374(+)	`TACAAC/TAGCCT`	8	--	us2k¹ int¹		0	--	--	--	--
rs13392448^1,2	C,F,A,	--	47166410(+)	`TAAAAT/CTGGCC`	8	--	us2k¹ int¹ tfbs³		7		NA WA EA	366
rs183955586^1,2		--	47166419(+)	`CCAGGC/TGCAGT`	8	--	us2k¹ int¹		0	--	--	--	--
rs147475335^1,2		--	47166618(+)	`TCCCCA/TCACTC`	8	--	us2k¹ int¹		0	--	--	--	--
rs148511486^1,2		--	47166715(+)	`TACAAC/TCTGGG`	8	--	us2k¹ int¹		0	--	--	--	--
rs187624199^1,2		--	47166769(+)	`GGTCTC/TATTTC`	8	--	us2k¹ int¹		0	--	--	--	--
rs13430346^1,2	C,	--	47166822(+)	`CTGCCC/TCAGGG`	8	--	int¹ us2k¹		3		WA NA	240
rs142751547^1,2		--	47166881(+)	`GGTCAC/TCCTAA`	8	--	us2k¹ int¹		0	--	--	--	--
rs13407588^1,2	C,	--	47167133(+)	`TGCCCA/GCCAAA`	8	--	us2k¹ int¹ tfbs³		3		WA NA	240

HapMap Linkage Disequilibrium report for TTC7A (47143296 - 47303276 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TTC7A
1 CNV: 50509
1 Indel: 50508

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTC7A

DNA2.0 Custom Variant and Variant Library Synthesis for TTC7A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TTC7A for disorders           About GeneDecksing

OMIM gene information: 609332    OMIM disorders: --

5 diseases for TTC7A:    About MalaCards

rheumatoid arthritis arthritis prostate cancer anemia

prostatitis

Human Genome Epidemiology (HuGE) Navigator: TTC7A (1 document)

Export disorders for TTC7A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TTC7A gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with TTC7A)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)^{1, 2, 3} Hirosawa M.... Ohara O. (1999)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{1, 2} Nakajima D.... Nagase T. (2002)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Genome-wide association of lipid-lowering response to statins in combined study populations. (PubMed id 20339536)¹ Barber M.J....Krauss R.M. (2010)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Genome-wide association study to identify single nucl eotide polymorphisms (SNPs) associated with the development of erectile dysfunc tion in African-American men after radiotherapy for prostate cancer. (PubMed id 20932654)¹ Kerns S.L....Rosenstein B.S. (2010)
Genetic variants at CD28, PRDM1 and CD2/CD58 are asso ciated with rheumatoid arthritis risk. (PubMed id 19898481)¹ Raychaudhuri S....Plenge R.M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57217	HGNC: 19750	AceView: TTC7A.1	Ensembl:ENSG00000068724	euGenes: HUgn57217
ECgene: TTC7A	H-InvDB: TTC7A

(According to HUGE)
About This Section

HUGE: KIAA1140

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TTC7A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TTC7A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TTC7A gene:
Search GeneIP for patents involving TTC7A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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TTC7A Gene

tetratricopeptide repeat domain 7A

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TTC7A Gene

tetratricopeptide repeat domain 7A

Aliasesfor TTC7A gene

Summariesfor TTC7A gene

Genomic Viewsfor TTC7A gene

Proteinsfor TTC7A gene

Protein Domains /Familiesfor TTC7A gene

Functionfor TTC7A gene

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Transcriptsfor TTC7A gene

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Orthologsfor TTC7A gene

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Genomic Variantsfor TTC7A gene

Disorders / Diseasesfor TTC7A gene

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External Searches for TTC7A gene

Genome Databases showing TTC7A gene

Other Databases showing TTC7A gene

Specialized Databases showing TTC7A gene

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Aliases
for TTC7A gene

Summaries
for TTC7A gene

Genomic Views
for TTC7A gene

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for TTC7A gene

Protein Domains /
Families
for TTC7A gene

Function
for TTC7A gene

Pathways & Interactions
for TTC7A gene

Drugs & Compounds
for TTC7A gene

Transcripts
for TTC7A gene

Expression
for TTC7A gene

Orthologs
for TTC7A gene

Paralogs
for TTC7A gene

Genomic Variants
for TTC7A gene

Disorders / Diseases
for TTC7A gene

Publications
for TTC7A gene

Intellectual Property
for TTC7A gene

Products
for TTC7A gene