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TTC4 Gene

protein-coding   GIFtS: 49
GCID: GC01P055181

Tetratricopeptide Repeat Domain 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tetratricopeptide Repeat Domain 41 2
TPR Repeat Protein 42 3
Tetratricopeptide Repeat Protein 42

External Ids:    HGNC: 123941   Entrez Gene: 72682   Ensembl: ENSG000002437257   OMIM: 6067535   UniProtKB: O958013   

Export aliases for TTC4 gene to outside databases

Previous GC identifers: GC01P055018 GC01P054008 GC01P054466 GC01P054551 GC01P054893 GC01P053295


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TTC4 Gene:
This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein
interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90.
Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs
from upstream gene MROH (maestro heat-like repeat family member 7) to this gene. (provided by RefSeq, Apr 2014)

GeneCards Summary for TTC4 Gene:
TTC4 (tetratricopeptide repeat domain 4) is a protein-coding gene. Diseases associated with TTC4 include sporadic breast cancer, and hepatitis c virus.

Gene Wiki entry for TTC4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TTC4 gene promoter:
         Bach2   Pax-2   Lmo2   Pax-2a   GATA-1   Evi-1   FAC1   POU2F1   POU2F1a   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTTC4 promoter sequence
   Search Chromatin IP Primers for TTC4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TTC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p32

TTC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTC4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P055181:  view genomic region     (about GC identifiers)

Start:
55,181,495 bp from pter      End:
55,208,330 bp from pter
Size:
26,836 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TTC4_HUMAN, O95801 (See protein sequence)
Recommended Name: Tetratricopeptide repeat protein 4  
Size: 387 amino acids; 44679 Da
Sequence caution: Sequence=AAD19853.1; Type=Frameshift; Positions=322;
Secondary accessions: Q53Y95 Q5TA96 Q9H3I2

Explore the universe of human proteins at neXtProt for TTC4: NX_O95801

Explore proteomics data for TTC4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys227
  • Modification sites at PhosphoSitePlus

  • See TTC4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001278262.1  NP_004614.3  

    ENSEMBL proteins: 
     ENSP00000360329  

    TTC4 Human Recombinant Protein Products:

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    TTC4 Assay Products:

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    Cloud-Clone Corp. ELISAs for TTC4
    Cloud-Clone Corp. CLIAs for TTC4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TTC: Tetratricopeptide (TTC) repeat domain containing

    3 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry O95801

    ProtoNet protein and cluster: O95801

    UniProtKB/Swiss-Prot: TTC4_HUMAN, O95801
    Similarity: Belongs to the TTC4 family
    Similarity: Contains 3 TPR repeats


    TTC4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for TTC4:
    tetratricopeptide-repeat containing gene isoform 4,ubiquitously expressed,localized within critical region,deleted
    in sporadic breast cancer

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    TTC4 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for TTC4:
     Decreased POU5F1-GFP protein e  Decreased number of cells in m  Increased cell death in HCC-19 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TTC4
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TTC4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTC4

    miRNA
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    Block miRNA regulation of human, mouse, rat TTC4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TTC4 (see all 9):
    hsa-miR-647 hsa-miR-1321 hsa-miR-3166 hsa-miR-1205 hsa-miR-1207-3p hsa-miR-145 hsa-miR-802 hsa-miR-216a
    SwitchGear 3'UTR luciferase reporter plasmidTTC4 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TTC4
    Predesigned siRNA for gene silencing in human, mouse, rat TTC4

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: TTC4 (NM_004623)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC4

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    mitochondrion2
    nucleus2
    cytoskeleton1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TTC4
    Interactions:

        Search GeneGlobe Interaction Network for TTC4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TTC4 (O958013 ENSP000003603294) via UniProtKB, MINT, STRING, and/or I2D (see all 42)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HSP90AA1P079003, ENSP000003351534I2D: score=3 STRING: ENSP00000335153
    TCOF1Q134283, ENSP000004068884I2D: score=1 STRING: ENSP00000406888
    RNF219Q5W0B13, ENSP000002820034I2D: score=1 STRING: ENSP00000282003
    AK6Q9Y3D83I2D: score=2 
    GRAMD1CQ8IYS03I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TTC4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TTC4 gene (2 alternative transcripts): 
    NM_001291333.1  NM_004623.4  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371281(uc001cxx.4 uc001cxv.3) ENST00000486621 ENST00000371284
    ENST00000486091
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TTC4 (see all 9):
    hsa-miR-647 hsa-miR-1321 hsa-miR-3166 hsa-miR-1205 hsa-miR-1207-3p hsa-miR-145 hsa-miR-802 hsa-miR-216a
    SwitchGear 3'UTR luciferase reporter plasmidTTC4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TTC4
    Predesigned siRNA for gene silencing in human, mouse, rat TTC4
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    OriGene ORF clones in mouse, rat for TTC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TTC4 (NM_004623)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TTC4
    OriGene qSTAR qPCR primer pairs in human, mouse for TTC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TTC4
      QuantiTect SYBR Green Assays in human, mouse, rat TTC4
      QuantiFast Probe-based Assays in human, mouse, rat TTC4

    Selected AceView cDNA sequences (see all 214):

    BM673384 CR620756 AK090964 AL043872 BC029191 AX746706 BX443464 Z39270 
    AI038486 AW027531 AK127008 CD244242 AL045710 AA382618 NM_198547 CR607810 
    BX281957 BX116560 BX282263 CR616622 AU280033 CR606917 AL117640 CR599311 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TTC4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGGTTGTT
    TTC4 Expression
    About this image

    TTC4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TTC4 Protein Expression
        Custom PCR Arrays for TTC4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TTC4
    OriGene qSTAR qPCR primer pairs in human, mouse for TTC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TTC4
    QuantiTect SYBR Green Assays in human, mouse, rat TTC4
    QuantiFast Probe-based Assays in human, mouse, rat TTC4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TTC4 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ttc41 , 5 tetratricopeptide repeat domain 41, 5 84.59(n)1
    82.6(a)1
      4 (49.68 cM)5
    723541  NM_028209.21  NP_082485.11 
     1066622565 
    chicken
    (Gallus gallus)
    Aves TTC41 tetratricopeptide repeat domain 4 64.36(n)
    62.6(a)
      429109  XM_426665.4  XP_426665.3 
    lizard
    (Anolis carolinensis)
    Reptilia TTC46
    tetratricopeptide repeat domain 4
    64(a)
    1 ↔ 1
    4(104501098-104513748)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.190662 Xenopus laevis transcribed sequence with weak similarity more 76.22(n)    AW644008.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc564112 similar to tetratricopeptide repeat domain 4 75.03(n)   393981  BC049428.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dpit471 , 3 DNA polymerase interacting tpr containing protein of more1 35(a)3
    44.63(n)1
    33.33(a)1
      42C33
    355651  NM_001273800.11  NP_001260729.11 
    worm
    (Caenorhabditis elegans)
    Secernentea C17G10.21 , 3 TPR domain3
    C17G10.21
    34(a)3
    46.84(n)1
    35.41(a)1
      II(5594708-5596310)3
    1739461  NM_062686.31  NP_495087.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CNS1(YBR155W)4
    CNS11
    TPR-containing co-chaperone; binds both Hsp82p (Hsp9 more4
    CNS11
    43.12(n)1
    31.16(a)1
      2(549771-550928)4
    8524521, 4  NP_009713.11, 4 


    ENSEMBL Gene Tree for TTC4 (if available)
    TreeFam Gene Tree for TTC4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TTC4 gene

    TTC4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TTC4
    PGOHUM00000232681


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TTC4 (see all 776)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1460676471,2
    C--53313403(+) TCTAC-/AAAAAA 1 -- int10--------
    rs2004716691,2
    --53316326(+) AGAGA-/GAGAGA 1 -- int10--------
    rs1497337961,2
    C--55201838(+) AGAGA-/AAGA  
     AAGAAAG
    GAGAG
    1 -- int10--------
    rs37534001,2
    C--55255895(+) CTTAGG/CTTCCC 1 -- us2k15Minor allele frequency- C:0.14WA NA EA 362
    rs1389870031,2
    --55255898(+) AGGTTA/CCCCTA 1 -- us2k10--------
    rs1867511471,2
    --55255943(+) GTTCTA/TATGGG 1 -- us2k10--------
    rs2020001231,2
    --55255959(+) ATGAG-/AAAAAA 1 -- us2k10--------
    rs1914384091,2
    --55256080(+) TGGAAA/CAGGAG 1 -- us2k10--------
    rs729079781,2
    C--55256115(+) GCTAGG/TACCAG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs120673951,2
    C,F--55256195(+) CCATGC/TGCCAT 1 -- us2k15Minor allele frequency- T:0.14WA NA EA 362

    HapMap Linkage Disequilibrium report for TTC4 (55181495 - 55208330 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for TTC4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv829904CNV Loss17160897
    nsv817614CNV Gain22305530
    nsv461561CNV Gain19166990
    nsv461594CNV Gain19166990
    dgv229n71CNV Gain21882294
    esv259828OTHER Complex20981092
    esv259647OTHER Complex20981092

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TTC4
    DNA2.0 Custom Variant and Variant Library Synthesis for TTC4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606753    OMIM disorders: --

    6 diseases for TTC4:    
    About MalaCards
    sporadic breast cancer    hepatitis c virus    hepatitis c    breast cancer
    hepatitis    malaria


    TTC4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TTC4

    Export disorders for TTC4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TTC4 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with TTC4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TTC4, a novel human gene containing the tetratricopeptide repeat and mapping to the region of chromosome 1p31 that is frequently deleted in sporadic breast cancer. (PubMed id 9933562)1, 2, 3 Su G.... Cowell J.K. (Genomics 1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    5. Molecular cochaperones: tumor growth and cancer treatment. (PubMed id 24278769)1 Calderwood S.K. (Scientifica (Cairo) 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)1 Liu B....Wang L.S. (J. Proteome Res. 2012)
    10. Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5. (PubMed id 21360678)1 Skarra D.V....Honkanen R.E. (Proteomics 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7268 HGNC: 12394 AceView: TTC4andFLJ46354 Ensembl:ENSG00000243725 euGenes: HUgn7268
    ECgene: TTC4 H-InvDB: TTC4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TTC4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TTC4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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