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Aliases for TTC39C Gene

Aliases for TTC39C Gene

  • Tetratricopeptide Repeat Domain 39C 2 3
  • TPR Repeat Protein 39C 3 4
  • C18orf17 3 4
  • Tetratricopeptide Repeat Protein 39C 3
  • Chromosome 18 Open Reading Frame 17 2
  • HsT2697 3

External Ids for TTC39C Gene

Previous Symbols for TTC39C Gene

  • C18orf17

Summaries for TTC39C Gene

GeneCards Summary for TTC39C Gene

TTC39C (Tetratricopeptide Repeat Domain 39C) is a Protein Coding gene. An important paralog of this gene is TTC39A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC39C Gene

Genomics for TTC39C Gene

Genomic Location for TTC39C Gene

Start:
23,992,773 bp from pter
End:
24,135,610 bp from pter
Size:
142,838 bases
Orientation:
Plus strand

Genomic View for TTC39C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC39C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC39C Gene

Regulatory Elements for TTC39C Gene

Proteins for TTC39C Gene

  • Protein details for TTC39C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N584-TT39C_HUMAN
    Recommended name:
    Tetratricopeptide repeat protein 39C
    Protein Accession:
    Q8N584
    Secondary Accessions:
    • B7WP63
    • J3QRR1
    • Q0VAJ2
    • Q8N284

    Protein attributes for TTC39C Gene

    Size:
    583 amino acids
    Molecular mass:
    65870 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH32684.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for TTC39C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TTC39C Gene

Proteomics data for TTC39C Gene at MOPED

Post-translational modifications for TTC39C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TTC39C Gene

Domains for TTC39C Gene

Gene Families for TTC39C Gene

HGNC:
  • TTC :Tetratricopeptide (TTC) repeat domain containing

Protein Domains for TTC39C Gene

UniProtKB/Swiss-Prot:

TT39C_HUMAN
Family:
  • Belongs to the TTC39 family.:
    • Q8N584
Similarity:
  • Contains 3 TPR repeats.:
    • Q8N584
genes like me logo Genes that share domains with TTC39C: view

Function for TTC39C Gene

Phenotypes for TTC39C Gene

GenomeRNAi human phenotypes for TTC39C:
genes like me logo Genes that share phenotypes with TTC39C: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TTC39C Gene

Localization for TTC39C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TTC39C Gene COMPARTMENTS Subcellular localization image for TTC39C gene
Compartment Confidence
cytosol 2
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for TTC39C Gene

Pathways for TTC39C Gene

SuperPathways for TTC39C Gene

No Data Available

Interacting Proteins for TTC39C Gene

Gene Ontology (GO) - Biological Process for TTC39C Gene

None

No data available for Pathways by source for TTC39C Gene

Transcripts for TTC39C Gene

Unigene Clusters for TTC39C Gene

Tetratricopeptide repeat domain 39C:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TTC39C Gene

No ASD Table

Relevant External Links for TTC39C Gene

GeneLoc Exon Structure for
TTC39C
ECgene alternative splicing isoforms for
TTC39C

Expression for TTC39C Gene

mRNA expression in normal human tissues for TTC39C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TTC39C Gene

This gene is overexpressed in Liver (10.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TTC39C Gene

SOURCE GeneReport for Unigene cluster for TTC39C Gene Hs.128576

genes like me logo Genes that share expressions with TTC39C: view

Orthologs for TTC39C Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TTC39C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100614628 36
  • 99.31 (n)
  • 99.31 (a)
TTC39C 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TTC39C 36
  • 93.66 (n)
  • 98.1 (a)
TTC39C 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TTC39C 36
  • 93.55 (n)
  • 98.08 (a)
TTC39C 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ttc39c 36
  • 89.31 (n)
  • 94.31 (a)
Ttc39c 16
Ttc39c 37
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TTC39C 37
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TTC39C 37
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia MGC125239 36
  • 88.76 (n)
  • 94.25 (a)
chicken
(Gallus gallus)
Aves TTC39C 36
  • 83.97 (n)
  • 90.28 (a)
TTC39C 37
  • 90 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TTC39C 37
  • 89 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17945 36
ttc39c 36
  • 80.69 (n)
  • 88.99 (a)
zebrafish
(Danio rerio)
Actinopterygii ttc39c 36
  • 68.73 (n)
  • 75.41 (a)
ttc39c 37
  • 73 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001215 36
  • 48.67 (n)
  • 39.79 (a)
worm
(Caenorhabditis elegans)
Secernentea C32D5.6 37
  • 20 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 39
Species with no ortholog for TTC39C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TTC39C Gene

ENSEMBL:
Gene Tree for TTC39C (if available)
TreeFam:
Gene Tree for TTC39C (if available)

Paralogs for TTC39C Gene

Paralogs for TTC39C Gene

Pseudogenes.org Pseudogenes for TTC39C Gene

genes like me logo Genes that share paralogs with TTC39C: view

Variants for TTC39C Gene

Sequence variations from dbSNP and Humsavar for TTC39C Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs10052 -- 24,020,079(+) GACGA(C/T)AGGAG intron-variant, utr-variant-3-prime
rs185825 -- 24,095,519(+) catgg(C/G/T)gaaac intron-variant
rs185826 -- 24,096,326(+) AATGT(A/G)TAATA intron-variant
rs192542 -- 24,110,931(+) TGGCA(A/C)TAAGT intron-variant
rs767931 -- 24,069,182(-) CCATA(G/T)AGGGG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for TTC39C Gene

Variant ID Type Subtype PubMed ID
nsv909459 CNV Gain 21882294
esv259739 OTHER Complex 20981092
nsv828189 CNV Gain 20364138
esv2678806 CNV Deletion 23128226
esv2641358 CNV Deletion 19546169
nsv909460 CNV Gain 21882294

Relevant External Links for TTC39C Gene

HapMap Linkage Disequilibrium report
TTC39C

Disorders for TTC39C Gene

No disorders were found for TTC39C Gene.

No data available for UniProtKB/Swiss-Prot for TTC39C Gene

Publications for TTC39C Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. DNA sequence and analysis of human chromosome 18. (PMID: 16177791) Nusbaum C. … Lander E.S. (Nature 2005) 3 4
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 3

Products for TTC39C Gene

Sources for TTC39C Gene

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