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Aliases for TTC39A Gene

Aliases for TTC39A Gene

  • Tetratricopeptide Repeat Domain 39A 2 3
  • Differentially Expressed In MCF7 With Estradiol Protein 6 3 4
  • TPR Repeat Protein 39A 3 4
  • C1orf34 3 4
  • DEME-6 3 4
  • Tetratricopeptide Repeat Protein 39A 3
  • Chromosome 1 Open Reading Frame 34 2
  • KIAA0452 4

External Ids for TTC39A Gene

Previous HGNC Symbols for TTC39A Gene

  • C1orf34

Previous GeneCards Identifiers for TTC39A Gene

  • GC01M051526
  • GC01M051752
  • GC01M049870

Summaries for TTC39A Gene

GeneCards Summary for TTC39A Gene

TTC39A (Tetratricopeptide Repeat Domain 39A) is a Protein Coding gene. An important paralog of this gene is TTC39C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC39A Gene

Genomics for TTC39A Gene

Regulatory Elements for TTC39A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TTC39A Gene

Start:
51,287,258 bp from pter
End:
51,345,116 bp from pter
Size:
57,859 bases
Orientation:
Minus strand

Genomic View for TTC39A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC39A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC39A Gene

Proteins for TTC39A Gene

  • Protein details for TTC39A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SRH9-TT39A_HUMAN
    Recommended name:
    Tetratricopeptide repeat protein 39A
    Protein Accession:
    Q5SRH9
    Secondary Accessions:
    • B7Z782
    • E7EQY9
    • G3XAF8
    • O43417
    • O75040
    • Q5SRH5
    • Q5SRH6
    • Q5SRH7
    • Q5SRH8
    • Q5SRI0
    • Q5SRI1
    • Q5SRI2
    • Q5T7S1
    • Q6PIU8
    • Q9BT24

    Protein attributes for TTC39A Gene

    Size:
    613 amino acids
    Molecular mass:
    69778 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH28374.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA32297.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA32297.1; Type=Frameshift; Positions=373; Evidence={ECO:0000305};

    Alternative splice isoforms for TTC39A Gene

neXtProt entry for TTC39A Gene

Proteomics data for TTC39A Gene at MOPED

Post-translational modifications for TTC39A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TTC39A Gene

Domains for TTC39A Gene

Gene Families for TTC39A Gene

HGNC:
  • TTC :Tetratricopeptide (TTC) repeat domain containing

Protein Domains for TTC39A Gene

Suggested Antigen Peptide Sequences for TTC39A Gene

Graphical View of Domain Structure for InterPro Entry

Q5SRH9

UniProtKB/Swiss-Prot:

TT39A_HUMAN :
  • Q5SRH9
Family:
  • Belongs to the TTC39 family.
Similarity:
  • Contains 3 TPR repeats.
genes like me logo Genes that share domains with TTC39A: view

Function for TTC39A Gene

Gene Ontology (GO) - Molecular Function for TTC39A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TTC39A: view

Phenotypes for TTC39A Gene

GenomeRNAi human phenotypes for TTC39A:
genes like me logo Genes that share phenotypes with TTC39A: view

Animal Model Products

CRISPR Products

miRNA for TTC39A Gene

miRTarBase miRNAs that target TTC39A

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC39A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TTC39A Gene

Localization for TTC39A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TTC39A Gene COMPARTMENTS Subcellular localization image for TTC39A gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for TTC39A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with TTC39A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TTC39A Gene

Pathways for TTC39A Gene

SuperPathways for TTC39A Gene

No Data Available

Interacting Proteins for TTC39A Gene

Gene Ontology (GO) - Biological Process for TTC39A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TTC39A: view

No data available for Pathways by source for TTC39A Gene

Transcripts for TTC39A Gene

Unigene Clusters for TTC39A Gene

Tetratricopeptide repeat domain 39A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC39A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC39A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^
SP1: - - - -
SP2: - - - - -
SP3: - - - - -
SP4: - - -
SP5: -
SP6: -
SP7: - -

ExUns: 22a · 22b · 22c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:

Relevant External Links for TTC39A Gene

GeneLoc Exon Structure for
TTC39A
ECgene alternative splicing isoforms for
TTC39A

Expression for TTC39A Gene

mRNA expression in normal human tissues for TTC39A Gene

mRNA differential expression in normal tissues according to GTEx for TTC39A Gene

This gene is overexpressed in Testis (7.9) and Kidney - Cortex (5.8).

Protein differential expression in normal tissues for TTC39A Gene

This gene is overexpressed in Stomach (20.5), Lung (18.8), and Islet of Langerhans (12.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TTC39A Gene

SOURCE GeneReport for Unigene cluster for TTC39A Gene Hs.112949

genes like me logo Genes that share expressions with TTC39A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for TTC39A Gene

Orthologs for TTC39A Gene

This gene was present in the common ancestor of animals.

Orthologs for TTC39A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TTC39A 35
  • 92.15 (n)
  • 93.98 (a)
TTC39A 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TTC39A 35
  • 88.68 (n)
  • 89.77 (a)
TTC39A 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ttc39a 35
  • 89.24 (n)
  • 93.65 (a)
Ttc39a 16
Ttc39a 36
  • 92 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TTC39A 35
  • 99.06 (n)
  • 99.25 (a)
TTC39A 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100910316 35
  • 89.26 (n)
  • 93.98 (a)
oppossum
(Monodelphis domestica)
Mammalia TTC39A 36
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TTC39A 36
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves TTC39A 35
  • 71.44 (n)
  • 77.72 (a)
TTC39A 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TTC39A 36
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.9518 35
ttc39a 35
  • 70.64 (n)
  • 75.27 (a)
zebrafish
(Danio rerio)
Actinopterygii ttc39a 35
  • 68.31 (n)
  • 70.13 (a)
ttc39a 36
  • 60 (a)
OneToMany
TTC39A (2 of 2) 36
  • 79 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C32D5.6 36
  • 36 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 40 (a)
OneToMany
Species with no ortholog for TTC39A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TTC39A Gene

ENSEMBL:
Gene Tree for TTC39A (if available)
TreeFam:
Gene Tree for TTC39A (if available)

Paralogs for TTC39A Gene

Paralogs for TTC39A Gene

Selected SIMAP similar genes for TTC39A Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with TTC39A: view

Variants for TTC39A Gene

Sequence variations from dbSNP and Humsavar for TTC39A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs635590 -- 51,288,140(+) AGCCC(A/G)GAACT utr-variant-3-prime
rs944230 -- 51,298,515(+) CACAG(A/G)CAGCT intron-variant, upstream-variant-2KB
rs1123308 -- 51,298,013(+) tcctg(C/T)gctcc intron-variant, upstream-variant-2KB
rs1539038 -- 51,325,891(+) CAGAC(A/G)GGCAC intron-variant
rs1547787 -- 51,322,578(+) TAAAT(A/G)AATGA upstream-variant-2KB, intron-variant

Relevant External Links for TTC39A Gene

HapMap Linkage Disequilibrium report
TTC39A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TTC39A Gene

Disorders for TTC39A Gene

Relevant External Links for TTC39A

Genetic Association Database (GAD)
TTC39A

No disorders were found for TTC39A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for TTC39A Gene

Publications for TTC39A Gene

  1. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PMID: 9455484) Seki N. … Ohara O. (DNA Res. 1997) 2 3 4
  2. Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor- positive breast carcinoma cell line. (PMID: 9461476) Kuang W.W. … Weigel R.J. (Nucleic Acids Res. 1998) 2 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TTC39A Gene

Sources for TTC39A Gene

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