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Aliases for TTC33 Gene

Aliases for TTC33 Gene

  • Tetratricopeptide Repeat Domain 33 2 3
  • Osmosis Responsive Factor 2 3
  • Osmosis-Responsive Factor 3 4
  • TPR Repeat Protein 33 3 4
  • Tetratricopeptide Repeat Protein 33 3
  • OSRF 3

External Ids for TTC33 Gene

Summaries for TTC33 Gene

GeneCards Summary for TTC33 Gene

TTC33 (Tetratricopeptide Repeat Domain 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC33 Gene

Genomics for TTC33 Gene

Genomic Location for TTC33 Gene

Start:
40,711,576 bp from pter
End:
40,755,975 bp from pter
Size:
44,400 bases
Orientation:
Minus strand

Genomic View for TTC33 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC33 Gene

Regulatory Elements for TTC33 Gene

Proteins for TTC33 Gene

  • Protein details for TTC33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PID6-TTC33_HUMAN
    Recommended name:
    Tetratricopeptide repeat protein 33
    Protein Accession:
    Q6PID6
    Secondary Accessions:
    • B2R6G0
    • O95105

    Protein attributes for TTC33 Gene

    Size:
    262 amino acids
    Molecular mass:
    29411 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TTC33 Gene

Proteomics data for TTC33 Gene at MOPED

Post-translational modifications for TTC33 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys179

Other Protein References for TTC33 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TTC33 Gene

Domains for TTC33 Gene

Gene Families for TTC33 Gene

HGNC:
  • TTC :Tetratricopeptide (TTC) repeat domain containing

Protein Domains for TTC33 Gene

UniProtKB/Swiss-Prot:

TTC33_HUMAN
Similarity:
  • Contains 3 TPR repeats.:
    • Q6PID6
genes like me logo Genes that share domains with TTC33: view

Function for TTC33 Gene

Gene Ontology (GO) - Molecular Function for TTC33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TTC33: view

Phenotypes for TTC33 Gene

GenomeRNAi human phenotypes for TTC33:
genes like me logo Genes that share phenotypes with TTC33: view

miRNA for TTC33 Gene

miRTarBase miRNAs that target TTC33

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TTC33 Gene

Localization for TTC33 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TTC33 Gene COMPARTMENTS Subcellular localization image for TTC33 gene
Compartment Confidence
cytosol 2
golgi apparatus 2
nucleus 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for TTC33 Gene

Pathways for TTC33 Gene

SuperPathways for TTC33 Gene

No Data Available

Interacting Proteins for TTC33 Gene

Gene Ontology (GO) - Biological Process for TTC33 Gene

None

No data available for Pathways by source for TTC33 Gene

Transcripts for TTC33 Gene

mRNA/cDNA for TTC33 Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TTC33 Gene

Tetratricopeptide repeat domain 33:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TTC33 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: -
SP2:
SP3: - -
SP4: - - -

Relevant External Links for TTC33 Gene

GeneLoc Exon Structure for
TTC33
ECgene alternative splicing isoforms for
TTC33

Expression for TTC33 Gene

mRNA expression in normal human tissues for TTC33 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TTC33 Gene

SOURCE GeneReport for Unigene cluster for TTC33 Gene Hs.348915

genes like me logo Genes that share expressions with TTC33: view

Orthologs for TTC33 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TTC33 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TTC33 36
  • 99.87 (n)
  • 99.62 (a)
TTC33 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TTC33 36
  • 91.98 (n)
  • 93.89 (a)
TTC33 37
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TTC33 36
  • 91.98 (n)
  • 93.89 (a)
TTC33 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ttc33 36
  • 81.81 (n)
  • 82.06 (a)
Ttc33 16
Ttc33 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TTC33 37
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TTC33 37
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ttc33 36
  • 83.46 (n)
  • 83.21 (a)
chicken
(Gallus gallus)
Aves TTC33 36
  • 78.16 (n)
  • 76.63 (a)
TTC33 37
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TTC33 37
  • 72 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.14643 36
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc33 36
  • 63.32 (n)
  • 59.46 (a)
zebrafish
(Danio rerio)
Actinopterygii ttc33 36
  • 60.15 (n)
  • 55.56 (a)
ttc33 37
  • 53 (a)
OneToOne
Species with no ortholog for TTC33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TTC33 Gene

ENSEMBL:
Gene Tree for TTC33 (if available)
TreeFam:
Gene Tree for TTC33 (if available)

Paralogs for TTC33 Gene

No data available for Paralogs for TTC33 Gene

Variants for TTC33 Gene

Sequence variations from dbSNP and Humsavar for TTC33 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs29742 -- 40,756,406(+) CAGCC(A/T)GAACG upstream-variant-2KB
rs29743 -- 40,755,178(+) AACTG(G/T)CGACG intron-variant
rs29744 -- 40,753,883(-) TTGTA(A/G)TTTAC intron-variant
rs168730 -- 40,738,435(+) taaaa(A/C/T)ataaa intron-variant
rs171605 -- 40,741,021(-) ggaca(A/G)agaga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TTC33 Gene

Variant ID Type Subtype PubMed ID
nsv880539 CNV Loss 21882294
esv2668589 CNV Deletion 23128226
esv2730119 CNV Deletion 23290073
dgv6040n71 CNV Loss 21882294
nsv880438 CNV Loss 21882294

Relevant External Links for TTC33 Gene

HapMap Linkage Disequilibrium report
TTC33

Disorders for TTC33 Gene

No disorders were found for TTC33 Gene.

No data available for UniProtKB/Swiss-Prot for TTC33 Gene

Publications for TTC33 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for TTC33 Gene

Sources for TTC33 Gene

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