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Aliases for TTC29 Gene

Aliases for TTC29 Gene

  • Tetratricopeptide Repeat Domain 29 2 3
  • Testis Development Protein NYD-SP14 3 4
  • TPR Repeat Protein 29 3 4
  • Protein TBPP2A 4
  • NYD-SP14 3
  • TBPP2A 3

External Ids for TTC29 Gene

Previous GeneCards Identifiers for TTC29 Gene

  • GC04M147847
  • GC04M147628
  • GC04M143355

Summaries for TTC29 Gene

GeneCards Summary for TTC29 Gene

TTC29 (Tetratricopeptide Repeat Domain 29) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC29 Gene

Genomics for TTC29 Gene

Regulatory Elements for TTC29 Gene

Genomic Location for TTC29 Gene

146,706,638 bp from pter
146,945,882 bp from pter
239,245 bases
Minus strand

Genomic View for TTC29 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC29 Gene

Proteins for TTC29 Gene

  • Protein details for TTC29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tetratricopeptide repeat protein 29
    Protein Accession:
    Secondary Accessions:
    • A4GU95
    • Q9BXB6

    Protein attributes for TTC29 Gene

    475 amino acids
    Molecular mass:
    55082 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAK29064.1; Type=Frameshift; Positions=467; Evidence={ECO:0000305};

    Alternative splice isoforms for TTC29 Gene


neXtProt entry for TTC29 Gene

Proteomics data for TTC29 Gene at MOPED

Post-translational modifications for TTC29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TTC29 Gene

Domains & Families for TTC29 Gene

Gene Families for TTC29 Gene

Protein Domains for TTC29 Gene

Suggested Antigen Peptide Sequences for TTC29 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 TPR repeats.
  • Contains 5 TPR repeats.
genes like me logo Genes that share domains with TTC29: view

Function for TTC29 Gene

Gene Ontology (GO) - Molecular Function for TTC29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TTC29: view
genes like me logo Genes that share phenotypes with TTC29: view

Animal Model Products

miRNA for TTC29 Gene

miRTarBase miRNAs that target TTC29

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC29

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for TTC29 Gene

Localization for TTC29 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TTC29 Gene

Pathways & Interactions for TTC29 Gene

SuperPathways for TTC29 Gene

No Data Available

Interacting Proteins for TTC29 Gene

Gene Ontology (GO) - Biological Process for TTC29 Gene


No data available for Pathways by source and SIGNOR curated interactions for TTC29 Gene

Drugs & Compounds for TTC29 Gene

No Compound Related Data Available

Transcripts for TTC29 Gene

Unigene Clusters for TTC29 Gene

Tetratricopeptide repeat domain 29:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC29

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC29 Gene

No ASD Table

Relevant External Links for TTC29 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TTC29 Gene

mRNA expression in normal human tissues for TTC29 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TTC29 Gene

This gene is overexpressed in Testis (x42.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TTC29 Gene

SOURCE GeneReport for Unigene cluster for TTC29 Gene Hs.378893

genes like me logo Genes that share expression patterns with TTC29: view

Protein tissue co-expression partners for TTC29 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TTC29 Gene

Orthologs for TTC29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TTC29 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TTC29 35
  • 87.52 (n)
  • 85.02 (a)
TTC29 36
  • 83 (a)
(Canis familiaris)
Mammalia TTC29 35
  • 89.19 (n)
  • 85.05 (a)
TTC29 36
  • 85 (a)
(Mus musculus)
Mammalia Ttc29 35
  • 77.92 (n)
  • 74.95 (a)
Ttc29 16
Ttc29 36
  • 74 (a)
(Pan troglodytes)
Mammalia TTC29 35
  • 99.3 (n)
  • 98.95 (a)
TTC29 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ttc29 35
  • 77.64 (n)
  • 75.58 (a)
(Monodelphis domestica)
Mammalia TTC29 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia TTC29 36
  • 59 (a)
(Gallus gallus)
Aves TTC29 35
  • 66.52 (n)
  • 51.78 (a)
TTC29 36
  • 48 (a)
(Anolis carolinensis)
Reptilia TTC29 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc29 35
  • 63.35 (n)
  • 51.81 (a)
(Danio rerio)
Actinopterygii si:ch211-256m12.5 35
  • 52.72 (n)
  • 40.72 (a)
TTC29 36
  • 35 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
-- 36
  • 24 (a)
Species with no ortholog for TTC29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TTC29 Gene

Gene Tree for TTC29 (if available)
Gene Tree for TTC29 (if available)

Paralogs for TTC29 Gene

No data available for Paralogs for TTC29 Gene

Variants for TTC29 Gene

Sequence variations from dbSNP and Humsavar for TTC29 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_033179 -
VAR_033180 -
VAR_033181 -

Structural Variations from Database of Genomic Variants (DGV) for TTC29 Gene

Variant ID Type Subtype PubMed ID
nsv461675 CNV Gain 19166990
nsv830107 CNV Gain 17160897
esv2728498 CNV Deletion 23290073
nsv880239 CNV Loss 21882294
esv2667709 CNV Deletion 23128226
esv2456671 CNV Deletion 19546169
esv2677680 CNV Deletion 23128226

Variation tolerance for TTC29 Gene

Residual Variation Intolerance Score: 90.35% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.87; 96.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TTC29 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTC29 Gene

Disorders for TTC29 Gene

Relevant External Links for TTC29

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TTC29: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TTC29 Gene

Publications for TTC29 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. ABCE1 is a highly conserved RNA silencing suppressor. (PMID: 25659154) KAorblane K. … Sarmiento C. (PLoS ONE 2015) 67
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  4. A genome-wide association meta-analysis of plasma AI^ peptides concentrations in the elderly. (PMID: 24535457) Chouraki V. … Lambert J.C. (Mol. Psychiatry 2014) 67
  5. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. (PMID: 21378988) (Nat. Genet. 2011) 67

Products for TTC29 Gene

Sources for TTC29 Gene

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