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Aliases for TTC24 Gene

Aliases for TTC24 Gene

  • Tetratricopeptide Repeat Domain 24 2 3
  • TPR Repeat Protein 24 4

External Ids for TTC24 Gene

Previous GeneCards Identifiers for TTC24 Gene

  • GC01P153365
  • GC01P154817
  • GC01P127907

Summaries for TTC24 Gene

GeneCards Summary for TTC24 Gene

TTC24 (Tetratricopeptide Repeat Domain 24) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC24 Gene

Genomics for TTC24 Gene

Regulatory Elements for TTC24 Gene

Genomic Location for TTC24 Gene

Start:
156,579,727 bp from pter
End:
156,586,770 bp from pter
Size:
7,044 bases
Orientation:
Plus strand

Genomic View for TTC24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC24 Gene

Proteins for TTC24 Gene

  • Protein details for TTC24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2A3L6-TTC24_HUMAN
    Recommended name:
    Tetratricopeptide repeat protein 24
    Protein Accession:
    A2A3L6
    Secondary Accessions:
    • Q5T3H7

    Protein attributes for TTC24 Gene

    Size:
    582 amino acids
    Molecular mass:
    63396 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TTC24 Gene

Proteomics data for TTC24 Gene at MOPED

Post-translational modifications for TTC24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TTC24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TTC24 Gene

Domains for TTC24 Gene

Gene Families for TTC24 Gene

HGNC:
  • TTC :Tetratricopeptide (TTC) repeat domain containing

Protein Domains for TTC24 Gene

Suggested Antigen Peptide Sequences for TTC24 Gene

Graphical View of Domain Structure for InterPro Entry

A2A3L6

UniProtKB/Swiss-Prot:

TTC24_HUMAN :
  • A2A3L6
Similarity:
  • Contains 8 TPR repeats.
genes like me logo Genes that share domains with TTC24: view

Function for TTC24 Gene

Gene Ontology (GO) - Molecular Function for TTC24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TTC24: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TTC24 Gene

Localization for TTC24 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TTC24 Gene COMPARTMENTS Subcellular localization image for TTC24 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TTC24 Gene

Pathways for TTC24 Gene

SuperPathways for TTC24 Gene

No Data Available

Interacting Proteins for TTC24 Gene

Gene Ontology (GO) - Biological Process for TTC24 Gene

None

No data available for Pathways by source for TTC24 Gene

Transcripts for TTC24 Gene

mRNA/cDNA for TTC24 Gene

(10) Selected AceView cDNA sequences:
(5) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TTC24 Gene

Tetratricopeptide repeat domain 24:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC24

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC24 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: -
SP2: -
SP3: - -

Relevant External Links for TTC24 Gene

GeneLoc Exon Structure for
TTC24
ECgene alternative splicing isoforms for
TTC24

Expression for TTC24 Gene

mRNA expression in normal human tissues for TTC24 Gene

mRNA differential expression in normal tissues according to GTEx for TTC24 Gene

This gene is overexpressed in Spleen (13.5), Small Intestine - Terminal Ileum (7.0), and Whole Blood (5.0).

Protein differential expression in normal tissues for TTC24 Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TTC24 Gene

SOURCE GeneReport for Unigene cluster for TTC24 Gene Hs.447851

genes like me logo Genes that share expressions with TTC24: view

Expression partners for TTC24 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TTC24 Gene

Orthologs for TTC24 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TTC24 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TTC24 35
  • 83.24 (n)
  • 77.08 (a)
TTC24 36
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TTC24 35
  • 83.14 (n)
  • 75.98 (a)
TTC24 36
  • 71 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ttc24 35
  • 73.9 (n)
  • 63.86 (a)
Ttc24 16
Ttc24 36
  • 63 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TTC24 35
  • 98.35 (n)
  • 98.05 (a)
TTC24 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ttc24 35
  • 75.43 (n)
  • 66.93 (a)
oppossum
(Monodelphis domestica)
Mammalia TTC24 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TTC24 36
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc24 35
  • 54.71 (n)
  • 47.84 (a)
Species with no ortholog for TTC24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TTC24 Gene

ENSEMBL:
Gene Tree for TTC24 (if available)
TreeFam:
Gene Tree for TTC24 (if available)

Paralogs for TTC24 Gene

No data available for Paralogs for TTC24 Gene

Variants for TTC24 Gene

Sequence variations from dbSNP and Humsavar for TTC24 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1970531 -- 156,587,162(+) GCTCA(G/T)GCCCC downstream-variant-500B
rs4661186 -- 156,581,300(+) AAGGG(G/T)GTCCT intron-variant
rs4661187 -- 156,581,440(+) AGAAG(A/G)AAAGA reference, missense
rs6679324 -- 156,581,075(+) GTGCT(A/G)TGGGA intron-variant
rs6679425 -- 156,581,176(+) CAGGA(A/C)GTTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TTC24 Gene

Variant ID Type Subtype PubMed ID
nsv523181 CNV Loss 19592680
nsv872472 CNV Loss 21882294
esv272218 CNV Insertion 20981092

Relevant External Links for TTC24 Gene

HapMap Linkage Disequilibrium report
TTC24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTC24 Gene

Disorders for TTC24 Gene

No disorders were found for TTC24 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TTC24 Gene

Publications for TTC24 Gene

  1. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4

Products for TTC24 Gene

Sources for TTC24 Gene

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