TTC24 Gene
protein-coding GIFtS: 34
GCID: GC01P156551
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tetratricopeptide repeat domain 24
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Aliases
for TTC24 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tetratricopeptide Repeat Domain 241 2 | | TPR Repeat Protein 242 3 | | Tetratricopeptide Repeat Protein 242 |
Export aliases for TTC24 gene to outside databasesPrevious GC identifers: GC01P153365 GC01P154817 GC01P127907 |
Summaries
for TTC24 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TTC24 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TTC24 gene promoter:
STAT5B STAT1 NF-1 RFX1 AML1a STAT1beta YY1 STAT1alpha Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for TTC24
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTC24 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q23.1 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q22TTC24 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P156551: view genomic region
(about GC identifiers)
Start:
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156,549,519 bp from pter |
End:
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156,556,562 bp from pter |
Size:
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7,044 bases |
Orientation:
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plus strand |
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Proteins
for TTC24 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TTC24_HUMAN, A2A3L6 (See
protein sequence)Recommended Name: Tetratricopeptide repeat protein 24 Size: 582 amino acids; 63396 Da
Secondary accessions: Q5T3H7Explore the universe of human proteins at neXtProt for TTC24: NX_A2A3L6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A2A3L6
TTC24 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001099139.2
ENSEMBL proteins: ENSP00000357220 ENSP00000339487 ENSP00000400414 ENSP00000357219
Human Recombinant Protein Products:
TTC24 Antibody Products:
Assay Products for TTC24: |
Protein
Domains /
Families
for TTC24 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TTC24 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A2A3L6ProtoNet protein and cluster: A2A3L6 UniProtKB/Swiss-Prot: TTC24_HUMAN, A2A3L6Similarity: Contains 8 TPR repeats |
Function
for TTC24 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTC24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTC24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TTC24 (NM_001105669) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TTC24 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TTC24 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC24 |
|
Pathways & Interactions
for TTC24 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TTC24
2 Interacting proteins for TTC24 (A2A3L63) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for TTC24 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TTC24
Search CenterWatch for drugs/clinical trials and news about TTC24
|
Transcripts
for TTC24 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TTC24 gene: NM_001105669.2 Unigene Cluster for TTC24: Tetratricopeptide repeat domain 24 Hs.447851 [show with all ESTs]Unigene Representative Sequence: NM_0011056697 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000368237 ENST00000340086 ENST00000495690 ENST00000413282 ENST00000478081
ENST00000462049 ENST00000368236(uc021pbf.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTC24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTC24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TTC24 (NM_001105669) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TTC24 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TTC24 |
3 DOTS entries: DT.95151110 DT.100862266 DT.40309534 10 AceView cDNA sequences: BQ216668 BM454588 BX414790 AW628680 BQ708417 BQ223352 AA256753 BG757011 AA504723 BG759602
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for TTC24 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 |
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| SP1: | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for TTC24
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Expression
for TTC24 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TTC24 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAAATGAGG
About this image
See TTC24 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.447851
SABiosciences Custom PCR Arrays for TTC24
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTC24
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TTC24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC24 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC24 |
Orthologs
for TTC24 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TTC24 gene from 2/10 species (see all 10) About this table
ENSEMBL Gene Tree for TTC24 (if available)
TreeFam Gene Tree for TTC24 (if available) |
Paralogs
for TTC24 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TTC24 gene
- TTC282 GPSM22 GPSM12
TTC24 for paralogs About GeneDecksing
|
Genomic Variants
for TTC24 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TTC24 (156549519 - 156556562 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TTC24: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTC24 |
|
Disorders
/ Diseases
for TTC24 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TTC24 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TTC24 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TTC24) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)
|
External Searches for TTC24 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TTC24 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TTC24 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TTC24 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TTC24 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TTC24 gene:
Search GeneIP for patents involving TTC24
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TTC24 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TTC24 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TTC24 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TTC24 | | | OriGene Protein Over-expression Lysate for TTC24 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TTC24 | | OriGene 3'-UTR Clone for TTC24 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TTC24 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TTC24 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TTC24 | | OriGene Custom Protein Services for TTC24 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TTC24 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TTC24 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TTC24 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TTC24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TTC24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TTC24 |
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 |  |  |  | |
| | | | Search Tocris compounds for TTC24 |
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 | | | TTC24 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC24 |
|  |  |  | | | | Search ThermoFisher Antibodies for TTC24 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TTC24 |
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