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Aliases for TTC23L Gene

Aliases for TTC23L Gene

  • Tetratricopeptide Repeat Domain 23-Like 2 3
  • Tetratricopeptide Repeat Protein 23-Like 3
  • MC25-1 3

External Ids for TTC23L Gene

Summaries for TTC23L Gene

GeneCards Summary for TTC23L Gene

TTC23L (Tetratricopeptide Repeat Domain 23-Like) is a Protein Coding gene. An important paralog of this gene is TTC23.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC23L Gene

Genomics for TTC23L Gene

Genomic Location for TTC23L Gene

Start:
34,838,833 bp from pter
End:
34,899,488 bp from pter
Size:
60,656 bases
Orientation:
Plus strand

Genomic View for TTC23L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC23L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC23L Gene

Regulatory Elements for TTC23L Gene

Proteins for TTC23L Gene

  • Protein details for TTC23L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PF05-TT23L_HUMAN
    Recommended name:
    Tetratricopeptide repeat protein 23-like
    Protein Accession:
    Q6PF05
    Secondary Accessions:
    • Q6RGS4
    • Q8N7R3
    • Q96LJ2

    Protein attributes for TTC23L Gene

    Size:
    361 amino acids
    Molecular mass:
    40837 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AK097766; Type=Frameshift; Positions=52; Evidence={ECO:0000305};

    Alternative splice isoforms for TTC23L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TTC23L Gene

Proteomics data for TTC23L Gene at MOPED

Post-translational modifications for TTC23L Gene

No Post-translational modifications

Other Protein References for TTC23L Gene

No data available for DME Specific Peptides for TTC23L Gene

Domains for TTC23L Gene

Protein Domains for TTC23L Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TTC23L: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TTC23L Gene

Function for TTC23L Gene

Gene Ontology (GO) - Molecular Function for TTC23L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22458338
genes like me logo Genes that share ontologies with TTC23L: view
genes like me logo Genes that share phenotypes with TTC23L: view

miRNA for TTC23L Gene

miRTarBase miRNAs that target TTC23L

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TTC23L Gene

Localization for TTC23L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TTC23L Gene COMPARTMENTS Subcellular localization image for TTC23L gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for TTC23L Gene

Pathways for TTC23L Gene

SuperPathways for TTC23L Gene

No Data Available

Gene Ontology (GO) - Biological Process for TTC23L Gene

None

No data available for Pathways by source for TTC23L Gene

Transcripts for TTC23L Gene

Unigene Clusters for TTC23L Gene

Tetratricopeptide repeat domain 23-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TTC23L Gene

No ASD Table

Relevant External Links for TTC23L Gene

GeneLoc Exon Structure for
TTC23L
ECgene alternative splicing isoforms for
TTC23L

Expression for TTC23L Gene

mRNA expression in normal human tissues for TTC23L Gene

mRNA differential expression in normal tissues according to GTEx for TTC23L Gene

This gene is overexpressed in Testis (18.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TTC23L Gene

SOURCE GeneReport for Unigene cluster for TTC23L Gene Hs.435742

genes like me logo Genes that share expressions with TTC23L: view

Orthologs for TTC23L Gene

This gene was present in the common ancestor of chordates.

Orthologs for TTC23L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TTC23L 36
  • 97.96 (n)
  • 96.1 (a)
TTC23L 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TTC23L 36
  • 79.38 (n)
  • 71.1 (a)
TTC23L 37
  • 51 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TTC23L 36
  • 86.72 (n)
  • 83.29 (a)
TTC23L 37
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ttc23l 36
  • 79.25 (n)
  • 72.57 (a)
Ttc23l 16
Ttc23l 37
  • 54 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TTC23L 37
  • 39 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ttc23l 36
  • 80.66 (n)
  • 75.21 (a)
lizard
(Anolis carolinensis)
Reptilia TTC23L 37
  • 28 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc23l 36
  • 56.61 (n)
  • 46.44 (a)
Species with no ortholog for TTC23L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TTC23L Gene

ENSEMBL:
Gene Tree for TTC23L (if available)
TreeFam:
Gene Tree for TTC23L (if available)

Paralogs for TTC23L Gene

Paralogs for TTC23L Gene

genes like me logo Genes that share paralogs with TTC23L: view

Variants for TTC23L Gene

Sequence variations from dbSNP and Humsavar for TTC23L Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs153012 -- 34,890,623(-) gggTT(C/T)TGGAG intron-variant
rs153013 -- 34,885,110(+) CAGTG(C/T)ATACT intron-variant
rs153017 -- 34,891,003(-) GAAAG(C/T)ACTAA intron-variant
rs163123 -- 34,846,539(+) cgggc(C/T)gacaa intron-variant
rs163233 -- 34,859,120(-) ATGAG(C/T)GGACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TTC23L Gene

Variant ID Type Subtype PubMed ID
nsv522144 CNV Loss 19592680
esv2730057 CNV Deletion 23290073
esv2235962 CNV Deletion 18987734
esv4902 CNV Deletion 18987735
nsv327644 CNV Loss 16902084
esv2664297 CNV Deletion 23128226
esv1002836 CNV Deletion 20482838
esv2730058 CNV Deletion 23290073
dgv1020e199 CNV Deletion 23128226

Relevant External Links for TTC23L Gene

HapMap Linkage Disequilibrium report
TTC23L

Disorders for TTC23L Gene

Relevant External Links for TTC23L

Genetic Association Database (GAD)
TTC23L
Human Genome Epidemiology (HuGE) Navigator
TTC23L
genes like me logo Genes that share disorders with TTC23L: view

No data available for UniProtKB/Swiss-Prot for TTC23L Gene

Publications for TTC23L Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. (PMID: 22458338) Simonis N. … Twizere J.C. (Retrovirology 2012) 3
  5. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3

Products for TTC23L Gene

Sources for TTC23L Gene

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