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Aliases for TTC23L Gene

Aliases for TTC23L Gene

  • Tetratricopeptide Repeat Domain 23-Like 2 3
  • Tetratricopeptide Repeat Protein 23-Like 3
  • MC25-1 3

External Ids for TTC23L Gene

Previous GeneCards Identifiers for TTC23L Gene

  • GC05P034876
  • GC05P034840
  • GC05P034787

Summaries for TTC23L Gene

GeneCards Summary for TTC23L Gene

TTC23L (Tetratricopeptide Repeat Domain 23-Like) is a Protein Coding gene. An important paralog of this gene is TTC23.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC23L Gene

Genomics for TTC23L Gene

Regulatory Elements for TTC23L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TTC23L Gene

34,838,833 bp from pter
34,899,488 bp from pter
60,656 bases
Plus strand

Genomic View for TTC23L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC23L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC23L Gene

Proteins for TTC23L Gene

  • Protein details for TTC23L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tetratricopeptide repeat protein 23-like
    Protein Accession:
    Secondary Accessions:
    • Q6RGS4
    • Q8N7R3
    • Q96LJ2

    Protein attributes for TTC23L Gene

    361 amino acids
    Molecular mass:
    40837 Da
    Quaternary structure:
    No Data Available
    • Sequence=AK097766; Type=Frameshift; Positions=52; Evidence={ECO:0000305};

    Alternative splice isoforms for TTC23L Gene


neXtProt entry for TTC23L Gene

Proteomics data for TTC23L Gene at MOPED

Post-translational modifications for TTC23L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TTC23L Gene

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for TTC23L

No data available for DME Specific Peptides for TTC23L Gene

Domains for TTC23L Gene

Protein Domains for TTC23L Gene


Suggested Antigen Peptide Sequences for TTC23L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TTC23L: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TTC23L Gene

Function for TTC23L Gene

Gene Ontology (GO) - Molecular Function for TTC23L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22458338
genes like me logo Genes that share ontologies with TTC23L: view
genes like me logo Genes that share phenotypes with TTC23L: view

Animal Model Products

CRISPR Products

miRNA for TTC23L Gene

miRTarBase miRNAs that target TTC23L

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC23L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TTC23L Gene

Localization for TTC23L Gene

Subcellular locations from

Jensen Localization Image for TTC23L Gene COMPARTMENTS Subcellular localization image for TTC23L gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TTC23L Gene

Pathways for TTC23L Gene

SuperPathways for TTC23L Gene

No Data Available

Gene Ontology (GO) - Biological Process for TTC23L Gene


No data available for Pathways by source for TTC23L Gene

Transcripts for TTC23L Gene

Unigene Clusters for TTC23L Gene

Tetratricopeptide repeat domain 23-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC23L

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC23L Gene

No ASD Table

Relevant External Links for TTC23L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TTC23L Gene

mRNA expression in normal human tissues for TTC23L Gene

mRNA differential expression in normal tissues according to GTEx for TTC23L Gene

This gene is overexpressed in Testis (18.2).

Protein differential expression in normal tissues for TTC23L Gene

This gene is overexpressed in Fetal Brain (49.2) and Platelet (19.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TTC23L Gene

SOURCE GeneReport for Unigene cluster for TTC23L Gene Hs.435742

genes like me logo Genes that share expressions with TTC23L: view

Expression partners for TTC23L Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TTC23L Gene

Orthologs for TTC23L Gene

This gene was present in the common ancestor of chordates.

Orthologs for TTC23L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TTC23L 35
  • 79.38 (n)
  • 71.1 (a)
TTC23L 36
  • 51 (a)
(Canis familiaris)
Mammalia TTC23L 35
  • 86.72 (n)
  • 83.29 (a)
TTC23L 36
  • 63 (a)
(Mus musculus)
Mammalia Ttc23l 35
  • 79.25 (n)
  • 72.57 (a)
Ttc23l 16
Ttc23l 36
  • 54 (a)
(Pan troglodytes)
Mammalia TTC23L 35
  • 97.96 (n)
  • 96.1 (a)
TTC23L 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Ttc23l 35
  • 80.66 (n)
  • 75.21 (a)
(Monodelphis domestica)
Mammalia TTC23L 36
  • 39 (a)
(Anolis carolinensis)
Reptilia TTC23L 36
  • 28 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc23l 35
  • 56.61 (n)
  • 46.44 (a)
Species with no ortholog for TTC23L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TTC23L Gene

Gene Tree for TTC23L (if available)
Gene Tree for TTC23L (if available)

Paralogs for TTC23L Gene

Paralogs for TTC23L Gene

genes like me logo Genes that share paralogs with TTC23L: view

Variants for TTC23L Gene

Sequence variations from dbSNP and Humsavar for TTC23L Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs153012 -- 34,890,623(-) gggTT(C/T)TGGAG intron-variant
rs153013 -- 34,885,110(+) CAGTG(C/T)ATACT intron-variant
rs153017 -- 34,891,003(-) GAAAG(C/T)ACTAA intron-variant
rs163123 -- 34,846,539(+) cgggc(C/T)gacaa intron-variant
rs163233 -- 34,859,120(-) ATGAG(C/T)GGACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TTC23L Gene

Variant ID Type Subtype PubMed ID
nsv522144 CNV Loss 19592680
esv2730057 CNV Deletion 23290073
esv2235962 CNV Deletion 18987734
esv4902 CNV Deletion 18987735
nsv327644 CNV Loss 16902084
esv2664297 CNV Deletion 23128226
esv1002836 CNV Deletion 20482838
esv2730058 CNV Deletion 23290073
dgv1020e199 CNV Deletion 23128226

Relevant External Links for TTC23L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTC23L Gene

Disorders for TTC23L Gene

Relevant External Links for TTC23L

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for TTC23L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for TTC23L Gene

Publications for TTC23L Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. (PMID: 22458338) Simonis N. … Twizere J.C. (Retrovirology 2012) 3
  5. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3

Products for TTC23L Gene

Sources for TTC23L Gene

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