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TTC14 Gene

protein-coding   GIFtS: 50
GCID: GC03P180319

Tetratricopeptide Repeat Domain 14

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tetratricopeptide Repeat Domain 141 2
TPR Repeat Protein 142 3
DRDL58132
PRO196302
Tetratricopeptide Repeat Protein 142
KIAA19803

External Ids:    HGNC: 246971   Entrez Gene: 1516132   Ensembl: ENSG000001637287   UniProtKB: Q96N463   

Export aliases for TTC14 gene to outside databases

Previous GC identifers: GC03P181640 GC03P181802 GC03P177724


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TTC14 Gene:
TTC14 (tetratricopeptide repeat domain 14) is a protein-coding gene. Diseases associated with TTC14 include malaria. GO annotations related to this gene include RNA binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TTC14 gene promoter:
         AML1a   AP-1   Tal-1   LUN-1   Cdc5   YY1   E47   Nkx6-1   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTTC14 promoter sequence
   Search Chromatin IP Primers for TTC14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TTC14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.33   Ensembl cytogenetic band:  3q26.33   HGNC cytogenetic band: 3q27.2

TTC14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TTC14 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P180319:  view genomic region     (about GC identifiers)

Start:
180,319,918 bp from pter      End:
180,335,616 bp from pter
Size:
15,699 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TTC14_HUMAN, Q96N46 (See protein sequence)
Recommended Name: Tetratricopeptide repeat protein 14  
Size: 770 amino acids; 88319 Da
Secondary accessions: G5E9X0 Q6UWJ7 Q8TF22
Alternative splicing: 3 isoforms:  Q96N46-1   Q96N46-2   Q96N46-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TTC14: NX_Q96N46

Explore proteomics data for TTC14 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys287
  • Modification sites at PhosphoSitePlus

  • See TTC14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001036066.1  NP_001275511.1  NP_597719.1  

    ENSEMBL proteins: 
     ENSP00000296015   ENSP00000420652   ENSP00000413743   ENSP00000420732   ENSP00000419562  
     ENSP00000372027   ENSP00000420278   ENSP00000418126   ENSP00000417415  

    TTC14 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TTC14
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TTC14
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    Novus Biologicals TTC14 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TTC14

    TTC14 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TTC14
    Novus Biologicals TTC14 Antibodies
    Abcam antibodies for TTC14
    Cloud-Clone Corp. Antibodies for TTC14
    ThermoFisher Antibodies for TTC14
    LSBio Antibodies in human, mouse, rat for TTC14

    TTC14 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TTC14
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TTC14
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TTC14
    Cloud-Clone Corp. CLIAs for TTC14


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TTC: Tetratricopeptide (TTC) repeat domain containing

    Selected InterPro protein domains (see all 6):
     IPR003029 Rbsml_prot_S1_RNA-bd_dom
     IPR011990 TPR-like_helical
     IPR012340 NA-bd_OB-fold
     IPR022967 RNA-binding_domain_S1
     IPR013026 TPR-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q96N46

    ProtoNet protein and cluster: Q96N46

    1 Blocks protein domain: IPB003029 RNA binding S1

    UniProtKB/Swiss-Prot: TTC14_HUMAN, Q96N46
    Similarity: Belongs to the TTC14 family
    Similarity: Contains 1 S1 motif domain
    Similarity: Contains 4 TPR repeats


    TTC14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0005515protein binding ----
         
    TTC14 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TTC14
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TTC14

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TTC14
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TTC14

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TTC14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TTC14 (see all 41):
    hsa-miR-15a hsa-miR-25 hsa-miR-29a hsa-miR-16-1* hsa-miR-570 hsa-miR-424 hsa-miR-3908 hsa-miR-497*
    SwitchGear 3'UTR luciferase reporter plasmidTTC14 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TTC14
    Predesigned siRNA for gene silencing in human, mouse, rat TTC14

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TTC14

    Clone
    Products:
         
    OriGene clones in human, mouse for TTC14 (see all 12)
    OriGene ORF clones in mouse, rat for TTC14
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TTC14 (NM_001042601)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC14

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TTC14
    Browse ESI BIO Cell Lines and PureStem Progenitors for TTC14 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TTC14
    Interactions:

        Search GeneGlobe Interaction Network for TTC14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for TTC14 (Q96N462, 3 ENSP000002960154) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158343, ENSP000003116954I2D: score=3 STRING: ENSP00000311695
    DGCR14Q96DF82, ENSP000002521374MINT-8338190 STRING: ENSP00000252137
    NKAPQ8N5F72, ENSP000003604644MINT-8339411 STRING: ENSP00000360464
    SF3B2Q134352, ENSP000003188614MINT-8333713 STRING: ENSP00000318861
    SNIP1Q8TAD82, ENSP000002962154MINT-8337332 STRING: ENSP00000296215
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TTC14



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TTC14 gene (3 alternative transcripts): 
    NM_001042601.2  NM_001288582.1  NM_133462.3  

    Unigene Cluster for TTC14:

    Tetratricopeptide repeat domain 14
    Hs.43213  [show with all ESTs]
    Unigene Representative Sequence: NM_001042601
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296015(uc003fkk.3) ENST00000491380 ENST00000412756(uc003fkl.3)
    ENST00000465065 ENST00000470669 ENST00000382584(uc003fkm.2) ENST00000462895
    ENST00000492617 ENST00000495660 ENST00000465625 ENST00000487397
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TTC14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TTC14 (see all 41):
    hsa-miR-15a hsa-miR-25 hsa-miR-29a hsa-miR-16-1* hsa-miR-570 hsa-miR-424 hsa-miR-3908 hsa-miR-497*
    SwitchGear 3'UTR luciferase reporter plasmidTTC14 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TTC14
    Predesigned siRNA for gene silencing in human, mouse, rat TTC14
    Clone
    Products:
         
    OriGene clones in human, mouse for TTC14 (see all 12)
    OriGene ORF clones in mouse, rat for TTC14
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TTC14 (NM_001042601)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TTC14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TTC14
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TTC14
    OriGene qSTAR qPCR primer pairs in human, mouse for TTC14
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TTC14
      QuantiTect SYBR Green Assays in human, mouse, rat TTC14
      QuantiFast Probe-based Assays in human, mouse, rat TTC14

    Additional mRNA sequence: 

    AB075860.2 AK055984.1 AL832052.1 AL832310.1 AL833086.2 AL833103.1 AY358762.1 BC027990.1 
    BC065823.1 

    14 DOTS entries:

    DT.120923989  DT.100824293  DT.120924016  DT.100824291  DT.100029373  DT.100000864  DT.441820  DT.91913111 
    DT.100029372  DT.100677196  DT.100824292  DT.86841139  DT.120923990  DT.91691197 

    Selected AceView cDNA sequences (see all 219):

    BX648669 AL040341 AV731023 BM967266 CA313297 AA496955 AL833103 BU963670 
    AI275998 BF111817 BU683419 CA313266 AI493256 AB075860 CA311556 AI866223 
    BM740270 CF541236 AI276522 AI800804 AW072640 BQ002349 AI088990 CA405596 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TTC14 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16
    SP1:              -     -                 -           -                                                               
    SP2:              -     -                 -                                                                           
    SP3:                    -                 -           -                                                               
    SP4:                                                                                            -                     
    SP5:              -     -                                                                                             


    ECgene alternative splicing isoforms for TTC14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TTC14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCAAAGATA
    TTC14 Expression
    About this image


    TTC14 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Limb (Muscoskeletal System)
    TTC14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TTC14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.43213
        Custom PCR Arrays for TTC14
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TTC14
    OriGene qSTAR qPCR primer pairs in human, mouse for TTC14
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TTC14
    QuantiTect SYBR Green Assays in human, mouse, rat TTC14
    QuantiFast Probe-based Assays in human, mouse, rat TTC14
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TTC14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TTC14 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ttc141 , 5 tetratricopeptide repeat domain 141, 5 87.91(n)1
    88.44(a)1
      3 (16.32 cM)5
    671201  NM_027619.31  NP_081895.21 
     337999555 
    chicken
    (Gallus gallus)
    Aves TTC141 tetratricopeptide repeat domain 14 68.46(n)
    64.09(a)
      424970  NM_001006552.1  NP_001006552.1 
    lizard
    (Anolis carolinensis)
    Reptilia TTC146
    tetratricopeptide repeat domain 14
    66(a)
    1 ↔ 1
    3(1646472-1660097)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ065688.12   -- 72.61(n)    BJ065688.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ttc141 tetratricopeptide repeat domain 14 55.83(n)
    55.33(a)
      541501  NM_001014314.1  NP_001014336.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG66216
    --
    21(a)
    1 ↔ 1
    3R(6715490-6719252)


    ENSEMBL Gene Tree for TTC14 (if available)
    TreeFam Gene Tree for TTC14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TTC14 gene
    3 SIMAP similar genes for TTC14 using alignment to 6 protein entries:     TTC14_HUMAN (see all proteins):
    DKFZp451L0319    FLJ00166    DKFZp313K2110

    TTC14 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TTC14
    PGOHUM00000233542


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TTC14 (see all 273)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1837703071,2
    --180317997(+) ATGAGA/GTGGGG 2 -- us2k10--------
    rs1880047701,2
    --180318003(+) TGGGGA/GAGGGT 2 -- us2k10--------
    rs1142023301,2
    C,F--180318014(+) TATCCT/CAGTGT 2 -- us2k11Minor allele frequency- C:0.02NA 120
    rs1924795341,2
    C--180318224(+) GTCTAA/TAATAA 2 -- us2k10--------
    rs1400502271,2
    --180318392(+) GGAGTC/TTCCCT 2 -- us2k10--------
    rs743423931,2
    C,F--180318450(+) CCCCCG/ACCTCC 2 -- us2k11Minor allele frequency- A:0.17WA 118
    rs1419767721,2
    C--180318552(+) AGAGAC/TGGGGT 2 -- us2k10--------
    rs1139735951,2
    C,F--180318601(+) CTCAAG/CTGATC 2 -- us2k12Minor allele frequency- C:0.10WA 120
    rs1463138331,2
    C--180318694(+) TGTTTA/GTTGCA 2 -- us2k10--------
    rs1394961271,2
    --180318735(+) TGCCTC/GGGTTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TTC14 (180319918 - 180335616 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TTC14: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TTC14
    DNA2.0 Custom Variant and Variant Library Synthesis for TTC14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for TTC14:    
    About MalaCards
    malaria


    TTC14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TTC14
    Human Genome Epidemiology (HuGE) Navigator: TTC14 (1 document)

    Export disorders for TTC14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TTC14 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with TTC14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Dynamic protein-protein interaction wiring of the human spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (Mol. Cell 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 151613 HGNC: 24697 AceView: TTC14 Ensembl:ENSG00000163728 euGenes: HUgn151613
    ECgene: TTC14 H-InvDB: TTC14

    (According to HUGE)
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    HUGE: KIAA1980

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TTC14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TTC14 gene:
    Search GeneIP for patents involving TTC14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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