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Aliases for TTC13 Gene

Aliases for TTC13 Gene

  • Tetratricopeptide Repeat Domain 13 2 3
  • TPR Repeat Protein 13 4

External Ids for TTC13 Gene

Previous GeneCards Identifiers for TTC13 Gene

  • GC01M228076
  • GC01M227348
  • GC01M229108
  • GC01M231041
  • GC01M201526

Summaries for TTC13 Gene

GeneCards Summary for TTC13 Gene

TTC13 (Tetratricopeptide Repeat Domain 13) is a Protein Coding gene. An important paralog of this gene is TTC6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TTC13 Gene

Genomics for TTC13 Gene

Regulatory Elements for TTC13 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TTC13 Gene

230,906,241 bp from pter
230,978,875 bp from pter
72,635 bases
Minus strand

Genomic View for TTC13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TTC13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC13 Gene

Proteins for TTC13 Gene

  • Protein details for TTC13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tetratricopeptide repeat protein 13
    Protein Accession:
    Secondary Accessions:
    • B1AQI1
    • B1AQI2
    • Q8IVP8
    • Q8NBI0
    • Q8ND20

    Protein attributes for TTC13 Gene

    860 amino acids
    Molecular mass:
    96813 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TTC13 Gene


neXtProt entry for TTC13 Gene

Proteomics data for TTC13 Gene at MOPED

Post-translational modifications for TTC13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TTC13 Gene

Domains & Families for TTC13 Gene

Gene Families for TTC13 Gene

Protein Domains for TTC13 Gene

Suggested Antigen Peptide Sequences for TTC13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 7 TPR repeats.
  • Contains 7 TPR repeats.
genes like me logo Genes that share domains with TTC13: view

Function for TTC13 Gene

Gene Ontology (GO) - Molecular Function for TTC13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TTC13: view

Phenotypes for TTC13 Gene

GenomeRNAi human phenotypes for TTC13:
genes like me logo Genes that share phenotypes with TTC13: view

Animal Model Products

miRNA for TTC13 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC13

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for TTC13 Gene

Localization for TTC13 Gene

Subcellular locations from

Jensen Localization Image for TTC13 Gene COMPARTMENTS Subcellular localization image for TTC13 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TTC13 Gene

Pathways & Interactions for TTC13 Gene

SuperPathways for TTC13 Gene

No Data Available

Interacting Proteins for TTC13 Gene

Gene Ontology (GO) - Biological Process for TTC13 Gene


No data available for Pathways by source and SIGNOR curated interactions for TTC13 Gene

Drugs & Compounds for TTC13 Gene

No Compound Related Data Available

Transcripts for TTC13 Gene

Unigene Clusters for TTC13 Gene

Tetratricopeptide repeat domain 13:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TTC13

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC13 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22 ^ 23 ^
SP1: - -
SP2: - - - -

ExUns: 24

Relevant External Links for TTC13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TTC13 Gene

mRNA expression in normal human tissues for TTC13 Gene

Protein differential expression in normal tissues from HIPED for TTC13 Gene

This gene is overexpressed in Placenta (50.6) and Adipocyte (13.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TTC13 Gene

SOURCE GeneReport for Unigene cluster for TTC13 Gene Hs.424788

genes like me logo Genes that share expression patterns with TTC13: view

Protein tissue co-expression partners for TTC13 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TTC13 Gene

Orthologs for TTC13 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TTC13 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TTC13 35
  • 93.04 (n)
  • 99.27 (a)
TTC13 36
  • 98 (a)
(Canis familiaris)
Mammalia TTC13 35
  • 93.29 (n)
  • 98.25 (a)
TTC13 36
  • 97 (a)
(Mus musculus)
Mammalia Ttc13 35
  • 85.67 (n)
  • 96.98 (a)
Ttc13 16
Ttc13 36
  • 87 (a)
(Pan troglodytes)
Mammalia TTC13 35
  • 99.88 (n)
  • 99.88 (a)
TTC13 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Ttc13 35
  • 86.07 (n)
  • 96.85 (a)
(Monodelphis domestica)
Mammalia TTC13 36
  • 91 (a)
(Ornithorhynchus anatinus)
Mammalia TTC13 36
  • 90 (a)
(Gallus gallus)
Aves TTC13 35
  • 81.36 (n)
  • 91.01 (a)
TTC13 36
  • 86 (a)
(Anolis carolinensis)
Reptilia TTC13 36
  • 79 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc13 35
  • 75.29 (n)
  • 84.92 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15150 35
(Danio rerio)
Actinopterygii Dr.17426 35
ttc13 35
  • 72.4 (n)
  • 79.83 (a)
ttc13 36
  • 77 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons SRFR1 35
  • 44.15 (n)
  • 30.71 (a)
(Oryza sativa)
Liliopsida Os07g0113700 35
  • 43.96 (n)
  • 30.86 (a)
Species with no ortholog for TTC13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TTC13 Gene

Gene Tree for TTC13 (if available)
Gene Tree for TTC13 (if available)

Paralogs for TTC13 Gene

Paralogs for TTC13 Gene

(1) SIMAP similar genes for TTC13 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with TTC13: view

Variants for TTC13 Gene

Sequence variations from dbSNP and Humsavar for TTC13 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs950029 -- 230,928,865(-) tggca(C/T)gctac intron-variant
rs1343674 -- 230,928,800(-) agcat(A/G)ctatc intron-variant
rs1890351 -- 230,933,906(+) TGTTA(A/C)AATTG intron-variant
rs1890352 -- 230,934,068(+) AAATA(C/T)GAGCC intron-variant
rs1890355 -- 230,946,344(+) ATCTA(C/T)TGTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TTC13 Gene

Variant ID Type Subtype PubMed ID
esv270056 CNV Insertion 20981092
esv272542 CNV Insertion 20981092

Variation tolerance for TTC13 Gene

Residual Variation Intolerance Score: 8.46% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.36; 81.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TTC13 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTC13 Gene

Disorders for TTC13 Gene

Relevant External Links for TTC13

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TTC13: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TTC13 Gene

Publications for TTC13 Gene

  1. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 67
  2. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 67
  3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67

Products for TTC13 Gene

Sources for TTC13 Gene

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