External Ids for TTC1 Gene
Previous GeneCards Identifiers for TTC1 Gene
This gene encodes a protein that belongs to the tetratrico peptide repeat superfamily of proteins. The encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneCards Summary for TTC1 Gene
TTC1 (Tetratricopeptide Repeat Domain 1) is a Protein Coding gene. Diseases associated with TTC1 include major depressive disorder and accelerated response to antidepressant drug treatment. GO annotations related to this gene include unfolded protein binding. An important paralog of this gene is SPAG1.